Conditions: Soft Tissue Sarcoma; Adult Soft Tissue Sarcoma; Resectable Soft Tissue Sarcoma
Interventions: Radiation: Neoadjuvant RT; Other: Pre-radiotherapy mpMRI; Other: Post-radiotherapy mpMRI; Procedure: Tumor resection
Sponsor: Centre Leon Berard
Not yet recruiting
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Multiparametric Quantitative MRI and Response to Neoadjuvant Radiotherapy for Soft-tissue Sarcoma
Posted: January 13th, 2023, 3:00pm GMT
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A Study to Test the Addition of the Drug Cabozantinib to Chemotherapy in Patients With Newly Diagnosed Osteosarcoma
Posted: January 13th, 2023, 3:00pm GMT
Conditions: Localized Osteosarcoma; Metastatic Osteosarcoma; Resectable Osteosarcoma; Unresectable Osteosarcoma
Interventions: Drug: Cabozantinib S-malate; Drug: Methotrexate; Drug: Doxorubicin Hydrochloride; Drug: Cisplatin; Procedure: X-Ray Imaging; Procedure: Computed Tomography; Procedure: Magnetic Resonance Imaging; Procedure: Bone Scan
Sponsors: Children's Oncology Group; National Cancer Institute (NCI)
Not yet recruiting -
Pazopanib With or Without Pembrolizumab for Metastatic Soft Tissue Sarcoma
Posted: January 11th, 2023, 3:00pm GMT
Condition: Soft Tissue Sarcoma
Intervention: Drug: pembrolizumab, pazopanib
Sponsor: Yonsei University
Not yet recruiting -
Multi-parametric Biomarker Development to Predict Malignant Conversion in Patients With Neurofibromatosis Type 1
Posted: January 10th, 2023, 3:00pm GMT
Conditions: Neurofibromatosis 1; Malignant Peripheral Nerve Sheath Tumor (MPNST) of Soft Tissue (Diagnosis); Atypical Neurofibroma
Intervention: Diagnostic Test: Whole Body Magnetic Resonance Imaging
Sponsor: Johns Hopkins University
Recruiting -
Collecting Blood and Tissue Sample Donations for Research for HIV/AIDS-Related Cancers
Posted: December 23rd, 2022, 3:00pm GMT
Conditions: Anal Carcinoma; Hematopoietic and Lymphoid Cell Neoplasm; HIV Infection; Kaposi Sarcoma; Lymphoma; Malignant Solid Neoplasm; Multicentric Castleman Disease; Plasmablastic Lymphoma; Recurrent Kaposi Sarcoma; Recurrent Lymphoma; Recurrent Plasmablastic Lymphoma; Transplant-Related Kaposi Sarcoma
Intervention: Procedure: Biospecimen Collection
Sponsors: AIDS Malignancy Consortium; National Cancer Institute (NCI)
Not yet recruiting -
A Phase I/II Study of RNA-lipid Particle (RNA-LP) Vaccines for Recurrent Pulmonary Osteosarcoma (OSA)
Posted: December 21st, 2022, 3:00pm GMT
Condition: Pulmonary Osteosarcoma
Intervention: Biological: RNA-LP vaccine
Sponsors: University of Florida; The V Foundation for Cancer Research
Not yet recruiting -
Cadonilimab in the Treatment of Advanced Soft Tissue Sarcoma
Posted: December 19th, 2022, 3:00pm GMT
Condition: Soft Tissue Sarcoma
Intervention: Device: Cadonilimab
Sponsor: Peking University Cancer Hospital & Institute
Not yet recruiting -
TAS-116 Plus Palbociclib in Breast and Rb-null Cancer
Posted: December 19th, 2022, 3:00pm GMT
Conditions: Advanced Breast Cancer; Treatment-Refractory Solid Tumors; Retinoblastoma Deficiency; SCLC; Soft Tissue Sarcoma; Endometrial Cancer; Bladder Cancer
Interventions: Drug: Palbociclib Oral Product; Drug: TAS-116
Sponsors: Brown University; Taiho Oncology, Inc.
Not yet recruiting -
Metastatic Leiomyosarcoma Biomarker Protocol
Posted: December 16th, 2022, 3:00pm GMT
Condition: Leiomyosarcoma
Intervention: Other: Plasma Collection
Sponsors: University of Michigan Rogel Cancer Center; National Cancer Institute (NCI)
Not yet recruiting -
Undifferentiated Embryonal Sarcoma of the Liver: Evaluation of the Relapse Profile According to the Therapies Administered
Posted: December 7th, 2022, 3:00pm GMT
Condition: Hepatic Sarcoma
Intervention:
Sponsor: University Hospital, Strasbourg, France
Recruiting -
Study of NY-ESO-1 TCR-T in Advanced Soft Tissue Sarcoma
Posted: November 17th, 2022, 3:00pm GMT
Condition: Advanced Soft-tissue Sarcoma
Intervention: Biological: NY-ESO-1 TCR-T
Sponsor: Shenzhen University General Hospital
Recruiting -
The Effects of Observer Presence and Type on Patients' Perception of Exercise in Patients With Soft Tissue Sarcoma
Posted: October 27th, 2022, 2:00pm GMT
Condition: Soft Tissue Sarcoma
Intervention: Other: Supervised Exercise by a physiotherapist via face to face
Sponsor: Istanbul Medeniyet University
Not yet recruiting -
Phase II Study of TAEST16001 in Soft Tissue Sarcoma
Posted: September 22nd, 2022, 2:00pm GMT
Condition: Soft Tissue Sarcoma
Intervention: Biological: NY-ESO-1(TCR Affinity Enhancing Specific T cell Therapy)
Sponsors: Sun Yat-sen University; Guangdong Xiangxue Precision Medical Technology Co., Ltd.
Recruiting -
A Study of Niraparib in People With Soft Tissue Sarcoma Who Have Changes in Their Tumor DNA
Posted: August 25th, 2022, 2:00pm GMT
Conditions: Sarcoma,Soft Tissue; Sarcoma Uterus
Intervention: Drug: Niraparib
Sponsors: Memorial Sloan Kettering Cancer Center; GlaxoSmithKline
Recruiting -
Chiauranib for Advanced or Unresectable Soft Tissue Sarcoma(STS)
Posted: August 11th, 2022, 2:00pm GMT
Condition: Soft Tissue Sarcoma
Intervention: Drug: Chiauranib
Sponsor: Chipscreen Biosciences, Ltd.
Recruiting -
Study on Clinical Features, Treatment Mode and Survival of Sarcoma
Posted: July 12th, 2022, 2:00pm GMT
Condition: Sarcoma
Intervention: Other: No intervention
Sponsor: Henan Cancer Hospital
Recruiting -
Theranostics in Soft Tissue Sarcoma Using a Vascular Disruption Approach
Posted: June 15th, 2022, 2:00pm GMT
Condition: Soft Tissue Sarcoma
Interventions: Drug: Ga-68-PSMA-11 PET/CT; Drug: Lu-177-ITG-PSMA-1
Sponsor: John O. Prior
Not yet recruiting -
Registration Study Sarcoma
Posted: May 13th, 2022, 2:00pm GMT
Condition: Sarcoma
Intervention: Other: Surgery
Sponsors: Radboud University Medical Center; Radiotherapiegroep
Recruiting -
Global collaboRAtion on CIC-DUX4, BCOR-CCN3, High-grade Undifferentiated Round Cell Sarcoma (URCS) Project
Posted: May 3rd, 2022, 2:00pm GMT
Condition: Undifferentiated Round Cell Sarcoma
Intervention: Other: data collection and analysis on Formalin-fixed paraffin embedded tissue and/or frozen tumoral tissue
Sponsor: Istituto Ortopedico Rizzoli
Recruiting -
A Study to Assess the Safety and Tolerability of CFT8634 in Locally Advanced or Metastatic SMARCB1-Perturbed Cancers, Including Synovial Sarcoma and SMARCB1-Null Tumors
Posted: May 2nd, 2022, 2:00pm GMT
Conditions: Synovial Sarcoma; Soft Tissue Sarcoma
Intervention: Drug: CFT8634
Sponsor: C4 Therapeutics, Inc.
Recruiting -
Habitat Escalated Adaptive Therapy (HEAT), With Neoadjuvant Radiation for Soft Tissue Sarcoma
Posted: March 29th, 2022, 2:00pm GMT
Condition: High Grade Sarcoma
Interventions: Radiation: Intensity Modulated Radiation Therapy (IMRT); Diagnostic Test: MRI
Sponsors: H. Lee Moffitt Cancer Center and Research Institute; Viewray Inc.
Recruiting -
A Study of LY2880070 and Gemcitabine in People With Ewing Sarcoma or Ewing-Like Sarcoma
Posted: March 11th, 2022, 3:00pm GMT
Conditions: Ewing Sarcoma; Ewing-Like Sarcoma
Interventions: Drug: LY2880070; Drug: Gemcitabine
Sponsor: Memorial Sloan Kettering Cancer Center
Recruiting -
Economic Evaluation of Sarcoma Patients Management in France
Posted: March 9th, 2022, 3:00pm GMT
Condition: Sarcoma
Intervention: Other: NETSARC network
Sponsors: Centre Leon Berard; École nationale supérieure des Mines Saint-Etienne France; Rennes University Hospital; Assistance Publique - Hôpitaux de Paris
Recruiting -
Clinical Trial of TQB2858 Injection in the Treatment of Advanced High-grade Sarcoma
Posted: March 2nd, 2022, 3:00pm GMT
Condition: Advanced High-grade Sarcoma
Intervention: Drug: TQB2858 injection
Sponsor: Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., Ltd.
Not yet recruiting -
Disulfiram With Copper Gluconate and Liposomal Doxorubicin in Treatment-Refractory Sarcomas
Posted: January 27th, 2022, 3:00pm GMT
Condition: Relapsed Sarcomas
Interventions: Drug: Disulfiram; Drug: Copper Gluconate; Drug: Liposomal Doxorubicin (Doxil)
Sponsor: Case Comprehensive Cancer Center
Recruiting -
A Phase II Study for 609A in the Treatment of Advanced Undifferentiated Pleomorphic Sarcoma
Posted: January 14th, 2022, 3:00pm GMT
Condition: Sarcoma, Soft Tissue
Intervention: Drug: Recombinant anti-PD-1 humanized monoclonal antibody injection
Sponsor: Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd.
Not yet recruiting -
Albumin-bound Paclitaxel Plus Camrelizumab for Advanced Soft Tissue Sarcoma.
Posted: January 12th, 2022, 3:00pm GMT
Condition: Soft Tissue Sarcoma
Interventions: Drug: Albumin-Bound Paclitaxel; Drug: Camrelizumab
Sponsor: Henan Cancer Hospital
Recruiting -
Predictive Models of Treatment Responses and Survival Outcomes in Patients With Soft Tissue Sarcoma
Posted: December 28th, 2021, 3:00pm GMT
Condition: Soft Tissue Sarcoma
Intervention: Other: Prediction model
Sponsor: West China Hospital
Recruiting -
Fruquintinib in the Treatment of Soft Tissue Sarcoma
Posted: December 2nd, 2021, 3:00pm GMT
Condition: Soft Tissue Sarcoma
Intervention: Drug: Fruquintinib
Sponsor: Fudan University
Recruiting -
A Phase 2 Clinical Study of Evaluation of Recombinant Anti-PD-1 Humanized Monoclonal Antibody Injection (609A) Combined With Doxorubicin Hydrochloride in the Treatment of Metastatic/Unresectable Non-specific Soft Tissue Sarcoma
Posted: November 30th, 2021, 3:00pm GMT
Condition: Sarcoma, Soft Tissue
Interventions: Drug: 609A; Drug: doxorubicin hydrochloride
Sponsor: Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd.
Not yet recruiting -
A Clinical Trial to Evaluate the Efficacy and Safety of Anotinib Hydrochloride Capsule Combined With Epirubicin Hydrochloride Versus Placebo Combined With Epirubicin Hydrochloride in First-line Treatment of Advanced Soft Tissue Sarcoma
Posted: November 16th, 2021, 3:00pm GMT
Condition: Soft Tissue Sarcoma
Interventions: Drug: Anlotinib hydrochloride capsule; Drug: Epirubicin; Drug: Arotinib hydrochloride capsule placebo
Sponsor: Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
Recruiting -
Sarcomas and DDR-Inhibition; a Combined Modality Study
Posted: November 10th, 2021, 3:00pm GMT
Condition: Soft Tissue Sarcoma Adult
Interventions: Combination Product: AZD1390 + radiotherapy; Combination Product: AZD7648 + radiotherapy
Sponsors: The Netherlands Cancer Institute; Leiden University Medical Center; University Medical Center Nijmegen
Recruiting -
Hypofractionated vs Conventional Fractionated RT in Soft Tissue Sarcomas
Posted: November 5th, 2021, 2:00pm GMT
Condition: Soft Tissue Sarcoma
Interventions: Radiation: Conventional Fractionated; Radiation: Hypofractionated
Sponsor: University of Wisconsin, Madison
Recruiting -
Surufatinib in Patients With Osteosarcoma and Soft Tissue Sarcoma
Posted: November 4th, 2021, 2:00pm GMT
Condition: Sarcoma
Intervention: Drug: Surufatinib
Sponsor: Sun Yat-sen University
Recruiting -
A Study of NOX66 Plus Doxorubicin in Anthracycline-naïve, Adult Patients With Soft Tissue Sarcoma
Posted: October 29th, 2021, 2:00pm GMT
Condition: Metastatic Soft-tissue Sarcoma
Interventions: Drug: NOX66; Drug: Doxorubicin
Sponsor: Noxopharm Limited
Recruiting -
Wide Excision of Soft Tissue Sarcomas in Combination With Interstitial Radiation Therapy
Posted: September 27th, 2021, 2:00pm GMT
Conditions: Sarcoma; Soft Tissue Sarcoma
Interventions: Radiation: Interstitial radiation therapy; Radiation: Postoperative external beam therapy
Sponsor: Blokhin's Russian Cancer Research Center
Recruiting -
Patient-Specific Computational Walking Models in Improving Surgical and Rehabilitation Treatment in Patients With Pelvic Sarcomas
Posted: September 23rd, 2021, 2:00pm GMT
Condition: Pelvic Sarcoma
Interventions: Other: Functional Assessment; Procedure: X-Ray Imaging
Sponsors: M.D. Anderson Cancer Center; National Cancer Institute (NCI)
Recruiting -
A Clinical Study of TK216 in Patients With Relapsed or Refractory Ewing's Sarcoma
Posted: September 16th, 2021, 2:00pm GMT
Condition: Sarcoma, Ewing
Intervention: Biological: TK216+Vincristin
Sponsor: Shanghai Pharmaceuticals Holding Co., Ltd
Not yet recruiting -
Neoadjuvant Chemotherapy and Retifanlimab in Patients With Selected Sarcomas (TORNADO)
Posted: July 20th, 2021, 2:00pm GMT
Condition: Resectable Sarcoma
Interventions: Drug: Doxorubicin; Drug: Ifosfamide; Drug: INCMGA00012
Sponsors: Institut Bergonié; Incyte Biosciences International Sàrl
Recruiting -
FHD-609 in Subjects With Advanced Synovial Sarcoma or Advanced SMARCB1-Loss Tumors
Posted: July 16th, 2021, 2:00pm GMT
Condition: Advanced Synovial Sarcoma
Intervention: Drug: FHD-609
Sponsor: Foghorn Therapeutics Inc.
Recruiting -
Neoadjuvant Irradiation of Extremity Soft Tissue Sarcoma With Ions
Posted: June 30th, 2021, 2:00pm GMT
Condition: Soft Tissue Sarcoma
Interventions: Radiation: Protons; Radiation: carbon ions
Sponsor: University Hospital Heidelberg
Recruiting -
Abemaciclib in Patients With HIV-associated and HIV-negative Kaposi Sarcoma
Posted: June 28th, 2021, 2:00pm GMT
Condition: Kaposi Sarcoma
Intervention: Drug: Abemaciclib
Sponsor: National Cancer Institute (NCI)
Recruiting -
Exercise and Soft Tissue Sarcoma
Posted: June 10th, 2021, 2:00pm GMT
Condition: Soft Tissue Sarcoma
Intervention: Other: neoadjuvant exercise therapy
Sponsors: Duke University; University of North Carolina, Chapel Hill
Recruiting -
Bintrafusp Alfa and Doxorubicin Hydrochloride in Treating Patients With Advanced Sarcoma
Posted: May 5th, 2021, 2:00pm GMT
Conditions: Advanced Soft-tissue Sarcoma; Metastatic Soft-tissue Sarcoma
Interventions: Drug: Bintrafusp alfa; Drug: Doxorubicin
Sponsors: Institut Bergonié; Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany
Recruiting -
Observational Study on Skeletal Ewing's Sarcoma
Posted: April 15th, 2021, 2:00pm GMT
Condition: Ewing Sarcoma of Bone
Intervention: Other: Treatment of Ewings Sarcoma of bone according clinical practice (includes drugs, surgery, radiotherapy or any other received treatments)
Sponsor: Italian Sarcoma Group
Recruiting -
Study of Adoptive Immunotherapy in Relapsed and Non-resectable Sarcomas After Multimodal Treatment.
Posted: March 17th, 2021, 2:00pm GMT
Condition: Sarcoma
Intervention: Drug: Autologous CIK
Sponsor: Prof. Franca Fagioli
Recruiting -
Lenvatinib and Pembrolizumab in People With Advanced Soft Tissue Sarcoma
Posted: March 5th, 2021, 3:00pm GMT
Condition: Advanced Sarcoma
Interventions: Drug: Lenvatinib; Drug: Pembrolizumab
Sponsors: Memorial Sloan Kettering Cancer Center; Merck Sharp & Dohme LLC; Parker Institute for Cancer Immunotherapy
Recruiting -
Sequential Neoadjuvant Chemotherapy in Soft Tissue Sarcoma
Posted: March 1st, 2021, 3:00pm GMT
Condition: Soft Tissue Sarcoma
Interventions: Drug: Ifosfamide; Drug: Doxorubicin
Sponsors: Oslo University Hospital; Haukeland University Hospital
Recruiting -
Study on Clinical Features and Outcomes of Breast Sarcoma
Posted: February 11th, 2021, 3:00pm GMT
Condition: Breast Sarcoma
Intervention: Other: Treatment of Breast Sarcoma according clinical practice (includes drugs, surgery or any other received treatments)
Sponsor: Italian Sarcoma Group
Recruiting -
Efficacy of the Combination of Nivolumab and Ipilimumab as a Treatment in Patients With Sarcoma of Rare Subtype
Posted: February 5th, 2021, 3:00pm GMT
Condition: Sarcoma
Interventions: Drug: Nivolumab and IPILIMUMAB; Drug: Pazopanib Oral Tablet [Votrient]
Sponsor: Centre Leon Berard
Recruiting -
Low Dose Continuous Cyclophosphamide vs Standard Doxorubicin in Advanced Sarcoma Elderly Patients
Posted: December 7th, 2020, 3:00pm GMT
Condition: Soft Tissue Sarcoma Adult
Interventions: Drug: Cyclophosphamide; Drug: Doxorubicin
Sponsors: Istituto Oncologico Veneto IRCCS; Ministry of Health, Italy
Recruiting -
Pre-operative RadiothErapy for Soft Tissue SarcOmas
Posted: November 5th, 2020, 3:00pm GMT
Condition: Soft Tissue Sarcoma Adult
Intervention: Radiation: Hypofractionation
Sponsor: McGill University Health Centre/Research Institute of the McGill University Health Centre
Recruiting -
Pemetrexed, Cisplatin With Soft Tissue Sarcoma
Posted: October 28th, 2020, 2:00pm GMT
Condition: Sarcoma,Soft Tissue
Intervention: Drug: pemetrexed+cisplatin
Sponsor: Yonsei University
Recruiting -
Study of Camrelizumab in Combination With Neoadjuvant Chemotherapy in the Treatment of High-risk Soft Tissue Sarcoma
Posted: October 28th, 2020, 2:00pm GMT
Condition: Soft Tissue Sarcoma
Intervention: Drug: Camrelizumab in Combination With Neoadjuvant Chemotherapy
Sponsors: Sun Yat-sen University; Jiangsu HengRui Medicine Co., Ltd.
Recruiting -
TVEC and Preop Radiation for Sarcoma (8 ml Dose)
Posted: October 22nd, 2020, 2:00pm GMT
Condition: Soft Tissue Sarcoma
Interventions: Drug: Talimogene Laherparepvec; Radiation: Radiotherapy
Sponsors: Varun Monga, MD; Amgen
Recruiting -
Pomalidomide Treatment in Patients With Kaposi Sarcoma
Posted: October 8th, 2020, 2:00pm GMT
Condition: Skin Kaposi Sarcoma
Intervention: Drug: Pomalidomide
Sponsor: National Cancer Institute (NCI)
Recruiting -
GALLANT: Metronomic Gemcitabine, Doxorubicin, Docetaxel and Nivolumab for Advanced Sarcoma
Posted: September 2nd, 2020, 2:00pm GMT
Condition: Sarcoma
Interventions: Drug: Gemcitabine; Drug: Doxorubicin; Drug: Docetaxel; Drug: Nivolumab
Sponsor: Sarcoma Oncology Research Center, LLC
Recruiting -
Efficacy of Pre-operative Prehabilitation in Patients With Limb Sarcoma
Posted: August 17th, 2020, 2:00pm GMT
Condition: Sarcoma
Intervention: Other: Surgical prehabilitation program.
Sponsor: Institut Claudius Regaud
Recruiting -
Hypofractionated Radiotherapy Followed by Immediate Surgical Resection in the Treatment of Soft Tissue Sarcomas
Posted: August 10th, 2020, 2:00pm GMT
Condition: Soft Tissue Sarcomas
Intervention: Radiation: Hypofractionated Radiotherapy
Sponsor: Vanderbilt-Ingram Cancer Center
Recruiting -
Enhanced Recovery After Surgery in Extremity Sarcoma
Posted: July 8th, 2020, 2:00pm GMT
Condition: Sarcoma
Intervention: Procedure: Enhanced Recovery After Surgery
Sponsor: Joshua Lawrenz
Recruiting -
Short Course Of Preoperative Radiotherapy in Head and Neck-, Trunk- and Extremity Soft Tissue Sarcomas
Posted: June 11th, 2020, 2:00pm GMT
Condition: Soft Tissue Sarcomas
Intervention: Radiation: pre-operative radiotherapy
Sponsors: The Netherlands Cancer Institute; Leiden University Medical Center
Recruiting -
The Combination of Sintilimab and AI (Doxorubicin, ADM/Ifosfamide, IFO) for the First Line Treatment of Select Type of Metastatic/Unresectable Soft Tissue Sarcoma
Posted: April 22nd, 2020, 2:00pm GMT
Condition: Sarcoma, Soft Tissue
Interventions: Drug: Sintilimab; Drug: Doxorubicin Hydrochloride; Drug: Ifosfamide
Sponsors: Fudan University; Zhejiang Cancer Hospital; Tongji Hospital; Xijing Hospital; Shanghai Zhongshan Hospital
Recruiting -
Interest of Peri Operative CHemotherapy In Patients With CINSARC High-risk Localized Soft Tissue Sarcoma
Posted: March 13th, 2020, 2:00pm GMT
Condition: Soft Tissue Sarcoma
Interventions: Drug: Standard of care + chemotherapy; Other: Standard of care
Sponsor: Institut Claudius Regaud
Recruiting -
NHS-IL12 Monotherapy and in Combination With M7824 in Advanced Kaposi Sarcoma
Posted: March 10th, 2020, 2:00pm GMT
Condition: Kaposi Sarcoma
Interventions: Drug: NHS-IL12; Drug: M7824
Sponsor: National Cancer Institute (NCI)
Recruiting -
Swiss Sarcoma Network: Prediction Model for Patient Selection in Sarcoma Care
Posted: March 9th, 2020, 2:00pm GMT
Condition: Sarcoma
Intervention:
Sponsors: Kantonsspital Winterthur KSW; SwissSarcomaNetwork
Recruiting -
Dose Reduction of Postoperative Radiation for Soft Tissue Sarcoma of the Arms and Legs
Posted: February 28th, 2020, 3:00pm GMT
Condition: Soft Tissue Sarcoma
Intervention: Radiation: Intensity-modulated radiation therapy (IMRT)
Sponsors: Memorial Sloan Kettering Cancer Center; National Institutes of Health (NIH)
Recruiting -
Study on TSR-042 in Advanced Clear Cell Sarcoma
Posted: February 18th, 2020, 3:00pm GMT
Condition: Sarcoma, Clear Cell
Intervention: Drug: TSR-042
Sponsors: Italian Sarcoma Group; GlaxoSmithKline
Recruiting -
The PET- Retroperitoneal Sarcoma Study
Posted: January 13th, 2020, 3:00pm GMT
Condition: Retroperitoneal Sarcoma
Intervention: Device: PET MRI scan
Sponsor: University Health Network, Toronto
Recruiting -
Neoadjuvant Irradiation of Retroperitoneal Soft Tissue Sarcoma With Ions Retro-Ion
Posted: January 6th, 2020, 3:00pm GMT
Condition: Sarcoma,Soft Tissue
Interventions: Radiation: Proton radiation; Radiation: Carbon Ion radiation
Sponsor: University Hospital Heidelberg
Recruiting -
Repeat or Single Quadratus Lumborum Block for the Reduction of Opioid Prescriptions After Surgery in Retroperitoneal Sarcoma Patients ("RESQU-SARC" Trial)
Posted: December 6th, 2019, 3:00pm GMT
Condition: Retroperitoneal Sarcoma
Interventions: Drug: Liposomal Bupivacaine; Drug: Quadratus Lumborum Block; Other: Questionnaire Administration
Sponsors: M.D. Anderson Cancer Center; National Cancer Institute (NCI)
Recruiting -
Anlotinib Combined With Toripalimab in Refractory and Advanced Soft-tissue Sarcoma
Posted: November 21st, 2019, 3:00pm GMT
Condition: Sarcoma,Soft Tissue
Intervention: Drug: anlotinib and toripalimab
Sponsor: Sun Yat-sen University
Recruiting -
Focused Ultrasound to Promote Immune Responses for Undifferentiated Pleomorphic Sarcoma
Posted: October 11th, 2019, 2:00pm GMT
Condition: Undifferentiated Pleomorphic Sarcoma
Intervention: Device: ExAblate 2000/2100 Magnetic Resonance-guided Focused Ultrasound (MRgFUS)
Sponsors: Matthew Bucknor; Focused Ultrasound Foundation
Recruiting -
Assessing Health-related Quality of Life in Sarcoma Patients
Posted: August 28th, 2019, 2:00pm GMT
Condition: Sarcoma
Intervention:
Sponsors: The Netherlands Cancer Institute; Radboud University Medical Center; Leiden University Medical Center; Centre Leon Berard; University Hospital Carl Gustav Carus; Heidelberg University; Johannes Gutenberg University Mainz; Fondazione IRCCS Istituto Nazionale dei Tumori, Milano; National Cancer Institute, Naples; Maria Sklodowska-Curie National Research Institute of Oncology; Hospital San Carlos, Madrid; Royal Marsden NHS Foundation Trust; Beatson West of Scotland Cancer Centre; University Hospital Southampton NHS Foundation Trust; Royal National Orthopaedic Hospital NHS Trust; Bank of Cyprus Oncology Centre; Institut Català d'Oncologia; University of Adelaide; King Hussein Cancer Center; Oslo University Hospital; Erasmus Medical Center; University Medical Center Groningen; Centre Oscar Lambret; Aretaieio Hospital; Hospital Universitario Fundación Jiménez Díaz; The Christie NHS Foundation Trust; Ain Shams University; Prince of Wales Hospital, Shatin, Hong Kong; Sheba Medical Center
Recruiting -
BIOmarker Driven Trial of VEGFR2 Inhibitor in Advanced Sarcoma
Posted: August 28th, 2019, 2:00pm GMT
Condition: Sarcoma
Intervention: Drug: Apatinib monotherapy
Sponsor: Ruijin Hospital
Recruiting -
Phase II Multicenter Study of Talimogene Laherparepvec in Classic or Endemic Kaposi Sarcoma
Posted: August 22nd, 2019, 2:00pm GMT
Condition: Kaposi Sarcoma
Intervention: Drug: Talimogene laherparepvec
Sponsor: Assistance Publique - Hôpitaux de Paris
Recruiting -
Gemcitabine and Docetaxel With Radiation in Adults With Soft Tissue Sarcoma of the Extremities
Posted: July 30th, 2019, 2:00pm GMT
Condition: Soft Tissue Sarcoma
Interventions: Drug: Gemcitabine; Drug: Docetaxel; Radiation: Radiation; Procedure: Surgical Resection; Other: Blood draws
Sponsors: Wake Forest University Health Sciences; National Cancer Institute (NCI)
Recruiting -
Registry of Sarcoma Patients Treated With Permanently Implantable LDR CivaSheet®
Posted: July 25th, 2019, 2:00pm GMT
Condition: Sarcoma
Intervention: Device: CivaSheet
Sponsors: CivaTech Oncology; TAB Clinical
Recruiting -
A Single-arm, Open, Phase II Study of Chidamide Combined With Toripalimab in Refractory and Advanced Soft-tissue Sarcoma
Posted: July 19th, 2019, 2:00pm GMT
Condition: Sarcoma
Intervention: Drug: chidamide and toripalimab
Sponsor: Sun Yat-sen University
Recruiting -
Apatinib Mesylate Combined With Doxorubicin and Ifosfamide in Advanced Soft-tissue Sarcoma
Posted: July 9th, 2019, 2:00pm GMT
Condition: Soft Tissue Sarcoma
Intervention: Drug: Apatinib Mesylate, doxorubicin, ifosfamide
Sponsors: Sun Yat-sen University; Jiangsu HengRui Medicine Co., Ltd.
Recruiting -
A Study of sEphB4-HSA in Kaposi Sarcoma
Posted: June 20th, 2019, 2:00pm GMT
Condition: Kaposi Sarcoma
Intervention: Drug: sEphB4-HSA
Sponsor: Vasgene Therapeutics, Inc
Recruiting -
National Clinical and Biological Sarcoma Database : An Initiative of the French Sarcoma Group
Posted: June 6th, 2019, 2:00pm GMT
Condition: Sarcoma
Interventions: Drug: Chemotherapy; Drug: Immunotherapeutic Agent; Drug: target treatment; Procedure: Surgery; Radiation: Radiotherapy
Sponsors: Institut Bergonié; French Sarcoma Group
Recruiting -
Recognition of Circulating Tumor DNA in Soft Tissue Sarcoma
Posted: April 1st, 2019, 2:00pm GMT
Condition: Sarcoma
Interventions: Device: Preoperative RT; Device: Postoperative RT; Drug: Chemotherapy; Other: Surgery
Sponsor: Medical College of Wisconsin
Recruiting -
Anlotinib Hydrochloride for Soft Tissue Sarcoma Patients.
Posted: March 26th, 2019, 2:00pm GMT
Condition: Soft Tissue Sarcoma
Intervention: Drug: Anlotinib Hydrochloride
Sponsors: Sun Yat-sen University; Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
Recruiting -
Talimogene Laherparepvec, Nivolumab and Trabectedin for Sarcoma
Posted: March 22nd, 2019, 2:00pm GMT
Condition: Sarcoma
Interventions: Drug: Talimogene Laherparepvec 100000000 PFU/1 ML Injection Suspension [IMLYGIC]; Drug: Nivolumab IV Soln 100 MG/10ML; Drug: Trabectedin 0.25 MG/1 VIAL Intravenous Powder for Solution
Sponsor: Sarcoma Oncology Research Center, LLC
Recruiting -
Randomized Trial in Advanced, Metastatic or Unresectable Soft Tissue Sarcoma After Failure of Standard Treatments.
Posted: February 12th, 2019, 3:00pm GMT
Condition: Advanced Soft Tissue Sarcoma
Interventions: Drug: Standard arm: Trabectedin in monotherapy; Drug: Experimental arm: Trabectedin + Olaparib
Sponsors: Italian Sarcoma Group; PharmaMar; AstraZeneca
Recruiting -
REtroperitoneal SArcoma Registry: an International Prospective Initiative
Posted: February 12th, 2019, 3:00pm GMT
Condition: Retroperitoneal Sarcoma
Intervention:
Sponsors: Fondazione IRCCS Istituto Nazionale dei Tumori, Milano; TransAtlantic Retroperitoneal Sarcoma Working Group
Recruiting -
Study of Exosomes in Monitoring Patients With Sarcoma (EXOSARC)
Posted: January 11th, 2019, 3:00pm GMT
Condition: Sarcoma
Intervention: Biological: Blood samples
Sponsor: Centre Georges Francois Leclerc
Recruiting -
A Study of Pazopanib and Durvalumab for Metastatic Soft Tissue Sarcoma
Posted: January 9th, 2019, 3:00pm GMT
Condition: Sarcoma
Intervention: Drug: Durvalumab, pazopanib
Sponsor: Yonsei University
Recruiting -
Radical Resection and HIPEC for Recurrent Retroperitoneal Sarcoma
Posted: January 3rd, 2019, 3:00pm GMT
Condition: Retroperitoneal Sarcoma
Intervention: Drug: Doxorubicin
Sponsor: National Cancer Centre, Singapore
Recruiting -
Molecular Profiling of Advanced Soft-tissue Sarcomas
Posted: December 21st, 2018, 3:00pm GMT
Condition: Soft Tissue Sarcoma
Interventions: Drug: Nilotinib; Drug: Ceritinib; Drug: Capmatinib; Drug: Lapatinib; Drug: Trametinib; Combination Product: Trametinib and Dabrafenib; Combination Product: Olaparib and Durvalumab; Drug: Palbociclib; Drug: Glasdegib; Drug: TAS-120; Other: Next Generation sequencing exome
Sponsors: Institut National de la Santé Et de la Recherche Médicale, France; Commissariat A L'energie Atomique; Institut Bergonié; Plateforme labellisée Inca - Institut Bergonié, Bordeaux; Plateforme labellisée Inca - Hôpital Européen Georges Pompidou, Paris; EUCLID Clinical Trial Platform
Recruiting -
SM-88 as Maintenance Therapy for Advanced Ewing's Sarcoma Patients and as Salvage Therapy for Sarcoma Patients
Posted: December 19th, 2018, 3:00pm GMT
Conditions: Sarcoma, Ewing; Sarcoma
Intervention: Drug: Combination metyrosine-derivative, low-dose methoxsalen, phenytoin and sirolimus (MPS)
Sponsors: Sarcoma Oncology Research Center, LLC; Joseph Ahmed Foundation; Tyme, Inc
Recruiting -
APX005M and Doxorubicin in Advanced Sarcoma
Posted: October 25th, 2018, 2:00pm GMT
Condition: Soft Tissue Sarcoma
Interventions: Drug: Doxorubicin; Drug: APX005M
Sponsors: Columbia University; Apexigen, Inc.
Recruiting -
NY-ESO-1-specific T Cell Receptor (TCR) T Cell in Sarcoma
Posted: March 12th, 2018, 2:00pm GMT
Conditions: Bone Sarcoma; Soft Tissue Sarcoma
Intervention: Biological: NY-ESO-1（TCR Affinity Enhancing Specific T cell Therapy）
Sponsors: Sun Yat-sen University; Guangdong Xiangxue Precision Medical Technology Co., Ltd.
Recruiting -
FAZA PET/MRI Sarcoma
Posted: February 1st, 2018, 3:00pm GMT
Condition: Sarcoma
Interventions: Drug: 18F-FAZA; Drug: Pimonidazole
Sponsor: University Health Network, Toronto
Recruiting -
Irinotecan and Temozolomide for Ewing Sarcoma
Posted: December 2nd, 2017, 3:00pm GMT
Condition: Ewing Sarcoma
Interventions: Drug: Vincristine; Drug: Temozolomide
Sponsor: Peking University People's Hospital
Recruiting -
An Observational Study on Epithelioid Sarcoma
Posted: April 4th, 2017, 2:00pm GMT
Condition: Epithelioid Sarcoma
Intervention: Other: Treatment for Epitheloid Sarcoma
Sponsor: Italian Sarcoma Group
Recruiting -
Impact of Locoregional Treatment of Soft Tissue Sarcoma on Status of Patients Aged 70 Years and Over
Posted: March 10th, 2017, 3:00pm GMT
Condition: Soft Tissue Sarcoma Adult
Intervention: Procedure: Geriatric assessment
Sponsors: Institut Bergonié; Ministry of Health, France
Recruiting -
sEphB4-HSA in Treating Patients With Kaposi Sarcoma
Posted: June 15th, 2016, 2:00pm GMT
Condition: Skin Kaposi Sarcoma
Interventions: Other: Laboratory Biomarker Analysis; Other: Pharmacological Study; Behavioral: Quality-of-Life Assessment; Biological: Recombinant EphB4-HSA Fusion Protein
Sponsors: AIDS Malignancy Consortium; National Cancer Institute (NCI); Vasgene Therapeutics, Inc; The Emmes Company, LLC; University of Arkansas
Recruiting -
CINSARC Signature and Correlation With Hemotherapy Efficacy in Soft-tissue Sarcomas. A Biomarker Study.
Posted: June 3rd, 2016, 2:00pm GMT
Condition: Soft-tissue Sarcomas
Intervention: Other: Procedure/Surgery
Sponsors: Institut Bergonié; National Cancer Institute, France; Ministry of Health, France
Recruiting -
A Study of Olaparib With Concomitant Radiotherapy in Locally Advanced/Unresectable Soft-tissue Sarcoma
Posted: June 1st, 2016, 2:00pm GMT
Condition: Soft-tissue Sarcoma
Interventions: Drug: Olaparib; Radiation: Concomitant Radiotherapy
Sponsors: Institut Bergonié; National Cancer Institute, France
Recruiting
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