Condition: Breast Cancer
Interventions: Diagnostic Test: MRI; Diagnostic Test: Lumbar puncture
Sponsor: Memorial Sloan Kettering Cancer Center
Not yet recruiting
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5250 items (5250 unread) in 74 feeds
Acinar Cell Carcinoma
(12 unread)
Acinic Cell Carcinoma
(18 unread)
Adenoid Cystic Carcinoma
(90 unread)
Adrenal Gland Cancer
(452 unread)
Ampulla Of Vater
(60 unread)
Anal Cancer
(494 unread)
Angiosarcoma
(130 unread)
Appendix Cancer
(85 unread)
Bile Duct Cancer
(664 unread)
Brain and CNS
(597 unread)
Carcinoid
(153 unread)
Endocrine/Neuroendocrine
(652 unread)
Gall Bladder Cancer
(338 unread)
Hemangioendothelioma
(117 unread)
Hepatoblastoma
(151 unread)
Pancreas
(60 unread)
Phyllodes
(26 unread)
PMP and Mucinous Tumors
(39 unread)
Rhabdomyosarcoma
(187 unread)
Sarcoma
(925 unread)
Trial - Brain Tumor (41 unread)
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Monitoring for Cancer Spread to the Central Nervous System (CNS) in People With Breast Cancer
Posted: November 23rd, 2021, 3:00pm GMT
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The BurnAlong Pilot Study for Adolescent and Young Adult Cancer Survivors
Posted: November 23rd, 2021, 3:00pm GMT
Conditions: Cancer; Cancer Metastatic; Neoplasms; Breast Cancer; Lung Cancer; Thyroid Cancer; Lymphoma; Lymphoma, Non-Hodgkin; Hodgkin Lymphoma; Leukemia; Sarcoma; Skin Cancer; Bone Cancer; Gynecologic Cancer; Pancreas Cancer; Multiple Myeloma; Colorectal Cancer; Gastrointestinal Cancer; Prostate Cancer; Glioblastoma; Brain Cancer; Head and Neck Cancer
Intervention: Behavioral: Virtual group based physical activity (BurnAlong) and Social Media Discussion Board
Sponsors: Cedars-Sinai Medical Center; Walter Reed National Military Medical Center
Not yet recruiting -
Quantitative Assessment of Radiation-induced Neuroinflammation - A Proof of Principle Study
Posted: November 22nd, 2021, 3:00pm GMT
Conditions: Brain Tumor; Medulloblastoma
Intervention: Drug: [18F]DPA714
Sponsor: St. Jude Children's Research Hospital
Recruiting -
Re-TREAT: Re-irradiation for Relapsed Brain Metastases
Posted: November 19th, 2021, 3:00pm GMT
Conditions: Cancer; Brain Metastases, Adult
Intervention: Radiation: Repeated stereotactic radiosurgery
Sponsor: Rigshospitalet, Denmark
Recruiting -
REMASTer: REcurrent Brain Metastases After SRS Trial
Posted: November 18th, 2021, 3:00pm GMT
Conditions: Brain Metastases; Radiation Necrosis; Recurrent Tumor; Recurrent Metastases
Interventions: Procedure: Radiation Therapy; Drug: Steroid Therapy; Procedure: Laser Interstitial Thermal Therapy
Sponsor: Monteris Medical
Not yet recruiting -
A Phase 1/2 Study of SONALA-001 and Exablate 4000 Type 2 in Patients With DIPG
Posted: November 17th, 2021, 3:00pm GMT
Condition: Diffuse Intrinsic Pontine Glioma
Intervention: Combination Product: SONALA-001 (ALA) and MR-Guided Focused Ultrasound device (MRgFUS)
Sponsors: SonALAsense, Inc.; InSightec
Not yet recruiting -
Trial of Preoperative Radiosurgery Versus Postoperative Stereotactic Radiotherapy for Resectable Brain Metastases
Posted: November 17th, 2021, 3:00pm GMT
Condition: Brain Metastases, Adult
Interventions: Radiation: preoperative radiosurgery; Radiation: postoperative hypofractionated stereotactic radiotherapy
Sponsors: Susanne Rogers; University of Basel; Technische Universität München
Not yet recruiting -
A Phase 1a/1b Study to Determine the Recommended Phase 2 Dose, of Tepotinib in Participants With MET Alterations and Brain Tumors
Posted: November 16th, 2021, 3:00pm GMT
Condition: Brain Tumor
Interventions: Drug: tepotinib; Drug: tepotinib plus osimertinib
Sponsor: M.D. Anderson Cancer Center
Not yet recruiting -
Brain Imaging, Nutrition, and Cognition in Breast Cancer Survivors
Posted: November 16th, 2021, 3:00pm GMT
Condition: Breast Cancer
Intervention:
Sponsor: Ohio State University
Not yet recruiting -
Post Mortem Tissue Donation of Pediatric Tumor Tissues and Cells
Posted: November 15th, 2021, 3:00pm GMT
Condition: Pediatric Cancer
Intervention: Other: Collection of post mortem tissue donation
Sponsor: Ann & Robert H Lurie Children's Hospital of Chicago
Recruiting -
The Impact of Resistance ExerciSe on Muscle Mass in GlioblaSToma Survivors
Posted: November 10th, 2021, 3:00pm GMT
Conditions: Glioblastoma Multiforme of Brain; Brain Cancer
Intervention: Behavioral: Circuit-based resistance exercise (CRT)
Sponsors: Nova Scotia Health Authority; Canadian Cancer Society (CCS)
Not yet recruiting -
Study of Screening Brain MRIs in Stage IV Breast Cancer
Posted: November 10th, 2021, 3:00pm GMT
Conditions: Triple Negative Breast Cancer; HER2-positive Breast Cancer; Hormone Receptor-positive Breast Cancer
Intervention: Diagnostic Test: Magnetic Resonance Imaging
Sponsors: H. Lee Moffitt Cancer Center and Research Institute; Florida Breast Cancer Foundation
Recruiting -
Feasibility and Acceptability of a Virtual 'Coping With Brain Fog' Intervention for Young Adults With Cancer
Posted: November 10th, 2021, 3:00pm GMT
Conditions: Cancer; Cognitive Dysfunction; Cognitive Impairment; Adolescents; Young Adults
Intervention: Behavioral: 'Coping with Brain Fog' program
Sponsors: University of Manitoba; CancerCare Manitoba
Not yet recruiting -
Wearable Devices and Biomarkers Project
Posted: November 4th, 2021, 2:00pm GMT
Conditions: Brain Cancer; Neurological Disorder; Neurological Cancer
Intervention:
Sponsor: CureScience
Recruiting -
Radiomic and Pathomic Study of Pituitary Adenoma Using Machine Learning
Posted: November 4th, 2021, 2:00pm GMT
Condition: Pituitary Neoplasms
Intervention: Diagnostic Test: Artificial intelligence model
Sponsor: Huashan Hospital
Recruiting -
Chemo-immunotherapy Using Ibrutinib Plus Indoximod for Patients With Pediatric Brain Cancer
Posted: November 3rd, 2021, 2:00pm GMT
Conditions: Ependymoma; Medulloblastoma; Glioblastoma; Primitive Neuroectodermal Tumor (PNET)
Interventions: Drug: Ibrutinib; Drug: Indoximod; Drug: Cyclophosphamide; Drug: Etoposide
Sponsors: Theodore S. Johnson; Augusta University
Not yet recruiting -
Osimertinib Combined With Bevacizumab in Patients With Brain Metastasis Epidermal Growth Factor Receptor (EGFR) Mutation Positive Metastatic Non-Small Cell Lung Cancer
Posted: November 2nd, 2021, 2:00pm GMT
Condition: Carcinoma, Non-Small-Cell Lung
Intervention: Drug: osimertinib oral and bevazizumab intravenously
Sponsor: Qingdao Central Hospital
Recruiting -
The Role of 5-Aminolevulinic Acid Fluorescence-Guided Surgery in Head and Neck Cancers: a Pilot Trial
Posted: November 1st, 2021, 2:00pm GMT
Conditions: Neoplasm; Skull Base Neoplasm
Intervention: Drug: 5-Aminolevulinic acid Hydrochloride
Sponsors: Icahn School of Medicine at Mount Sinai; NX Development Corp
Recruiting -
Stereotactic Radiotherapy in Oligometastatic Brain Disease: a Randomised Phase III Study Comparing Hypofractionated Stereotactic Radiation Therapy (3*10 Gy) to the Historical Single-dose Radiosurgery (1*20 to 25 Gy) With Medico-economic Evaluation.
Posted: November 1st, 2021, 2:00pm GMT
Conditions: Brain Metastasis; Oligoprogression
Interventions: Radiation: Hypofractionated SRT (stereotactic radiotherapy); Radiation: Historical single-dose SRS (stereotactic radiosurgery)
Sponsors: Centre Francois Baclesse; Association de Neuro-Oncologues d'Expression Francaise
Not yet recruiting -
A Study of the Drug Selinexor With Radiation Therapy in Patients With Newly-Diagnosed Diffuse Intrinsic Pontine Glioma and H3 K27M-Mutant High-Grade Glioma
Posted: October 29th, 2021, 2:00pm GMT
Conditions: Anaplastic Astrocytoma; Diffuse Intrinsic Pontine Glioma; Diffuse Midline Glioma, H3 K27M-Mutant; Glioblastoma; Malignant Glioma
Interventions: Radiation: Radiation Therapy; Drug: Selinexor
Sponsor: National Cancer Institute (NCI)
Not yet recruiting -
Comparaison Between MRI Alone or Combined With Positron Emission Tomography for Brain Metastasis Diagnosis
Posted: October 27th, 2021, 2:00pm GMT
Condition: Brain Metastases, Adult
Intervention:
Sponsors: Centre de recherche du Centre hospitalier universitaire de Sherbrooke; Université de Sherbrooke
Recruiting -
Testing the Addition of the Chemotherapy Drug Lomustine (Gleostine®) to the Usual Treatment (Temozolomide and Radiation Therapy) for Newly Diagnosed MGMT Methylated Glioblastoma
Posted: October 27th, 2021, 2:00pm GMT
Conditions: Glioblastoma; Gliosarcoma
Interventions: Drug: Lomustine; Radiation: Photon Beam Radiation Therapy; Other: Quality-of-Life Assessment; Other: Questionnaire Administration; Drug: Temozolomide
Sponsors: NRG Oncology; National Cancer Institute (NCI)
Not yet recruiting -
Phase 2 Trial of PEP-CMV Vaccine Targeting CMV Antigen for Newly Diagnosed Pediatric HGG and DIPG and Recurrent Medulloblastoma
Posted: October 27th, 2021, 2:00pm GMT
Conditions: High Grade Glioma; Diffuse Intrinsic Pontine Glioma; Recurrent Medulloblastoma
Interventions: Biological: PEP-CMV; Drug: Temozolomide; Biological: Tetanus Diphtheria Vaccine
Sponsor: Nationwide Children's Hospital
Not yet recruiting -
Simulation-Free Hippocampal-Avoidance Whole Brain Radiotherapy Using Diagnostic MRI-Based and Cone Beam Computed Tomography-Guided On-Table Adaptive Planning in a Novel Ring Gantry Radiotherapy Device
Posted: October 27th, 2021, 2:00pm GMT
Condition: Intracranial Metastatic Disease From Any Solid Malignancy
Intervention: Device: Ethos Therapy
Sponsors: Washington University School of Medicine; Varian Medical Systems
Not yet recruiting -
The Efficacy of HLX208 (BRAF V600E Inhibitor) for Refractory Primary Brain Tumors With BRAF Mutation After First-line Treatment
Posted: October 26th, 2021, 2:00pm GMT
Condition: Brain Tumor, Primary
Intervention: Drug: HLX208
Sponsor: Shanghai Henlius Biotech
Recruiting -
AMG 193, Methylthioadensine (MTA) Cooperative Protein Arginine Methyltransferase 5 (PRMT5) Inhibitor, Alone and in Combination With Docetaxel in Advanced Methylthioadenosine Phosphorylase (MTAP)-Null Solid Tumors
Posted: October 26th, 2021, 2:00pm GMT
Condition: Advanced MTAP-null Solid Tumors
Interventions: Drug: AMG 193; Drug: Docetaxel
Sponsor: Amgen
Not yet recruiting -
Natural Progesterone for the Treatment of Recurrent Glioblastoma
Posted: October 25th, 2021, 2:00pm GMT
Conditions: Gliosarcoma; Recurrent Glioblastoma
Interventions: Other: Quality-of-Life Assessment; Other: Questionnaire Administration; Biological: Therapeutic Progesterone
Sponsor: Emory University
Recruiting -
Optimizing Neurocognition With Whole Brain Radiation Therapy (WBRT) Using Upfront Pulsed Reduced Dose-Rate (PRDR) Technique
Posted: September 16th, 2021, 2:00pm GMT
Condition: Brain Metastases
Interventions: Drug: Memantine -Twice Daily or Extended Release; Radiation: WBRT utilizing the PRDR technique
Sponsor: Medical College of Wisconsin
Recruiting -
Study of DSP-0390 in Patients With Recurrent High-Grade Glioma
Posted: August 26th, 2021, 2:00pm GMT
Conditions: High Grade Glioma; Glioblastoma Multiforme
Intervention: Drug: DSP-0390
Sponsor: Sumitomo Dainippon Pharma Oncology, Inc
Recruiting -
Toripalimab Combined With Anlotinib and SBRT in Patients With Untreated Brain Metastases of Driven Gene-negative NSCLC
Posted: August 25th, 2021, 2:00pm GMT
Condition: NSCLC
Interventions: Drug: Toripalimab; Drug: Anlotinib; Drug: SBRT 7Gy✖️5 QD
Sponsor: Hubei Cancer Hospital
Recruiting -
Patient Perceptions Around Quality of Care Through Telemedicine in Neuro-Oncology
Posted: August 3rd, 2021, 2:00pm GMT
Conditions: Central Nervous System Neoplasm; Leptomeningeal Neoplasm; Metastatic Malignant Neoplasm in the Brain; Primary Brain Neoplasm
Interventions: Other: Electronic Health Record Review; Other: Survey Administration
Sponsor: M.D. Anderson Cancer Center
Recruiting -
Durvalumab (MEDI4736) and Radiosurgery (fSRT vs. PULSAR) for the Treatment of Non-Small Cell Lung Cancer Brain Metastases
Posted: May 17th, 2021, 2:00pm GMT
Condition: Brain Metastases From Non-small Cell Lung Cancer
Interventions: Radiation: Stereotactic Radiation Therapy; Drug: Durvalumab
Sponsor: University of Texas Southwestern Medical Center
Not yet recruiting -
Fluorescence Detection of Adult Primary Central Nervous System Tumors With Tozuleristide and the Canvas System
Posted: February 8th, 2021, 3:00pm GMT
Condition: Central Nervous System Tumor
Interventions: Drug: tozuleristide; Device: Canvas imaging system; Procedure: Surgical resection of tumor
Sponsors: John Yu; Blaze Bioscience Inc.
Recruiting -
Neoepitope-based Personalized DNA Vaccine Approach in Pediatric Patients With Recurrent Brain Tumors
Posted: June 17th, 2019, 2:00pm GMT
Condition: Pediatric Recurrent Brain Tumor
Interventions: Biological: Personalized neoantigen DNA vaccine; Device: TDS-IM System; Procedure: Peripheral blood draw
Sponsors: Washington University School of Medicine; Children's Discovery Institute
Not yet recruiting -
Detection of Brain Metastasis by MRI in Metastatic Colorectal Cancer Patients
Posted: October 3rd, 2018, 2:00pm GMT
Condition: Metastatic Colon Cancer
Intervention: Device: Magnetic resonance imaging
Sponsor: Poitiers University Hospital
Recruiting -
A Phase 1b Study of PTC596 in Children With Newly Diagnosed Diffuse Intrinsic Pontine Glioma and High Grade Glioma
Posted: July 30th, 2018, 2:00pm GMT
Conditions: High Grade Glioma; Diffuse Intrinsic Pontine Glioma
Interventions: Drug: PTC596; Radiation: Radiotherapy
Sponsors: Nationwide Children's Hospital; PTC Therapeutics
Recruiting -
Feasibility and Preliminary Efficacy of a Mindfulness-based Intervention for Children and Young Adults With High Grade or High-Risk Cancer and Their Caregivers
Posted: May 29th, 2018, 2:00pm GMT
Conditions: Glioblastomas; Sarcoma; Astrocytoma; Brain Cancer; Leukemia
Interventions: Behavioral: Enhanced Mindfulness Intervention; Behavioral: Psychoeducation
Sponsor: National Cancer Institute (NCI)
Recruiting -
A Study to Assess the Safety and Tolerability of AZD1390 Given With Radiation Therapy in Patients With Brain Cancer
Posted: February 6th, 2018, 3:00pm GMT
Conditions: Recurrent Glioblastoma Multiforme; Primary Glioblastoma Multiforme; Brain Neoplasms, Malignant; Leptomeningeal Disease (LMD)
Interventions: Radiation: Radiation Therapy; Drug: AZD1390
Sponsor: AstraZeneca
Recruiting -
Cerebral Neuroinflammation During Major Depressive Episode
Posted: October 19th, 2017, 2:00pm GMT
Condition: Depressive Disorder
Intervention: Diagnostic Test: Cerebral neuroinflammation evaluation
Sponsors: University Hospital, Toulouse; Institut National de la Santé Et de la Recherche Médicale, France
Recruiting -
APL-101 Study of Subjects With NSCLC With c-Met EXON 14 Skip Mutations and c-Met Dysregulation Advanced Solid Tumors
Posted: June 5th, 2017, 2:00pm GMT
Conditions: Solid Tumor; Advanced Cancer; Renal Cancer; Gastric Cancer; Gastroesophageal Junction Adenocarcinoma; NSCLC; Lung Cancer; Brain Tumor; Glioblastoma Multiforme
Intervention: Drug: APL-101 Oral Capsules
Sponsor: Apollomics Inc.
Recruiting -
Testing the Ability of AMG 232 (KRT 232) to Get Into the Tumor in Patients With Brain Cancer
Posted: April 11th, 2017, 2:00pm GMT
Conditions: Glioblastoma; Gliosarcoma; MGMT-Unmethylated Glioblastoma; Recurrent Glioblastoma
Interventions: Other: Laboratory Biomarker Analysis; Drug: MDM2 Inhibitor KRT-232; Other: Pharmacological Study; Radiation: Radiation Therapy
Sponsor: National Cancer Institute (NCI)
Recruiting