Conditions: Astroblastoma; BCOR ITD Sarcoma; CNS Sarcoma; Unclassified Tumor, Malignant
Intervention:
Sponsor: Children's National Research Institute
Recruiting
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Acinar Cell Carcinoma
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International Rare Brain Tumor Registry
Posted: January 26th, 2023, 3:00pm GMT
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MRS of Glioma Genomics
Posted: January 26th, 2023, 3:00pm GMT
Condition: Glioma
Intervention: Diagnostic Test: MRI
Sponsor: Institut National de la Santé Et de la Recherche Médicale, France
Not yet recruiting -
A Study of Temodar With PCI-24781 for Patients With Recurrent Glioma
Posted: January 26th, 2023, 3:00pm GMT
Conditions: Recurrent High Grade Glioma; Anaplastic Astrocytoma; Anaplastic Oligodendroglioma; Glioblastoma; Gliosarcoma
Interventions: Drug: PCI 24781; Drug: Temozolomide
Sponsors: University of Nebraska; Xynomic Pharmaceuticals, Inc.
Not yet recruiting -
Phase II Trial of the PARP Inhibitor Niraparib and PD-1 Inhibitor Dostarlimab in Patients With Advanced Cancers With Active Progressing Brain Metastases (STARLET)
Posted: January 26th, 2023, 3:00pm GMT
Condition: Brain Metastases
Interventions: Drug: Niraparib; Drug: Dostarlimab
Sponsor: M.D. Anderson Cancer Center
Not yet recruiting -
GRETeL: Tumor Response to Standard Radiotherapy and TMZ Patients With GBM
Posted: January 24th, 2023, 3:00pm GMT
Conditions: Glioblastoma; Glioma, Malignant
Intervention:
Sponsors: Duke University; Personalis, Inc.
Not yet recruiting -
Reducing the Incidence of Symptomatic Brain Metastases With MRI Surveillance
Posted: January 20th, 2023, 3:00pm GMT
Conditions: Brain Metastases; Nonsmall Cell Lung Cancer Stage III
Interventions: Diagnostic Test: MRI of the Brain; Other: Blood draws; Other: Quality of Life Questionnaires
Sponsors: Wake Forest University Health Sciences; National Cancer Institute (NCI)
Not yet recruiting -
SILibinin in NSCLC and BC Patients With Single Brain METastasis (SILMET)
Posted: January 19th, 2023, 3:00pm GMT
Conditions: Brain Metastases, Adult; Non Small Cell Lung Cancer; Breast Cancer
Interventions: Dietary Supplement: Silibinin; Other: Placebo
Sponsor: Alessia Pellerino
Recruiting -
Microscopy Imaging of Whole-mount Stained Human Tissues
Posted: January 18th, 2023, 3:00pm GMT
Conditions: Tumor, Brain; Tumor, Breast; Tumor Skin
Intervention:
Sponsor: National Taiwan University Hospital
Not yet recruiting -
Brain Representation of Acquisition in Humans of Motor-Sensory Skills
Posted: January 18th, 2023, 3:00pm GMT
Conditions: Epilepsy; Cerebral Tumor
Intervention: Other: use of a theremin-type musical instrument
Sponsor: Fondation Ophtalmologique Adolphe de Rothschild
Not yet recruiting -
Adenovirus Mediated Suicide Gene Therapy With Radiotherapy in Progressive Astrocytoma.
Posted: January 16th, 2023, 3:00pm GMT
Conditions: Malignant Glioma of Brain; Astrocytoma; Malignant Astrocytoma; Brain Tumor; Glioma; Brain Cancer; Glioblastoma; Glioblastoma Multiforme; GBM
Intervention: Biological: Ad5-yCD/mutTKSR39rep-ADP adenovirus and fractionated stereotactic radiosurgery (fSRS)
Sponsor: Henry Ford Health System
Recruiting -
Study of Neoantigen-specific Adoptive T Cell Therapy for Newly Diagnosed o6-methylguanine-DNA-methyltransferase (MGMT) Negative Glioblastoma Multiforme (GBM)
Posted: January 13th, 2023, 3:00pm GMT
Condition: Glioblastoma Multiforme of Brain
Interventions: Biological: TVI-Brain-1; Procedure: Standard of Care; Radiation: Radiotherapy; Drug: Temozolomide
Sponsor: TVAX Biomedical
Not yet recruiting -
AssesSment of Early deteCtion basEd oN liquiD Biopsy in Intracranial Tumors
Posted: January 10th, 2023, 3:00pm GMT
Condition: Intracranial Tumors
Intervention: Device: early detection test
Sponsors: Zhujiang Hospital; Guangzhou Burning Rock Dx Co., Ltd.
Recruiting -
MeFAMP for Imaging System A Amino Acid Transport in Primary and Metastatic Brain Tumors
Posted: January 9th, 2023, 3:00pm GMT
Conditions: Healthy Volunteers; Recurrent Glioma; Brain Metastases From Extra-cranial Solid Tumors
Intervention: Drug: [F-18]MeFAMP PET
Sponsor: University of Alabama at Birmingham
Not yet recruiting -
A Phase II Study of Tucatinib and Ado-trastuzumab Emtansine (T-DM1) in Patients With HER2-positive Metastatic Solid Tumors and Metastases to Brain (TUCATEMEB)
Posted: January 6th, 2023, 3:00pm GMT
Conditions: Metastatic Solid Tumor; Brain Metastases
Interventions: Drug: Trastuzumab emtansine; Drug: Tucatinib
Sponsors: M.D. Anderson Cancer Center; Genentech, Inc.; Seagen Inc.
Not yet recruiting -
Genetic and Molecular Risk Profiles of Pediatric Malignant Brain Tumors in China
Posted: January 5th, 2023, 3:00pm GMT
Conditions: Medulloblastoma; Central Nervous System Tumor, Pediatric; Ependymoma; Germ Cell Tumor; Glioma; Brain Tumor, Pediatric
Intervention:
Sponsor: Beijing Tiantan Hospital
Recruiting -
Antisecretory Factor Glioblastoma Phase 2
Posted: January 2nd, 2023, 3:00pm GMT
Condition: Glioblastoma
Interventions: Dietary Supplement: Salovum; Dietary Supplement: Placebo egg yolk powder
Sponsors: Peter Siesjö; Lund University
Recruiting -
Evaluation of the Contribution of NODDI Protocol Tractography in Brain Tumor Surgery
Posted: December 30th, 2022, 3:00pm GMT
Condition: Malignant Brain Tumor
Intervention: Other: NODDI TRACT
Sponsor: GCS Ramsay Santé pour l'Enseignement et la Recherche
Not yet recruiting -
A Phase 1/2 Study of Oral IRAK-4 Inhibitor CA-4948 in Combination With Pembrolizumab Following Stereotactic Radiosurgery in Patients With Melanoma Brain Metastases
Posted: December 30th, 2022, 3:00pm GMT
Condition: Melanoma Metastatic in the Brain
Interventions: Drug: CA-4948; Drug: Pembrolizumab
Sponsors: University of Florida; Merck Sharp & Dohme LLC
Not yet recruiting -
A Phase 1b / 2 Drug Resistant Immunotherapy With Activated, Gene Modified Allogeneic or Autologous γδ T Cells (DeltEx) in Combination With Maintenance Temozolomide in Subjects With Recurrent or Newly Diagnosed Glioblastoma
Posted: December 23rd, 2022, 3:00pm GMT
Condition: Glioblastoma
Interventions: Biological: Autologous genetically modified gamma-delta T cells; Biological: Allogeneic genetically modified gamma-delta T cells
Sponsor: In8bio Inc.
Not yet recruiting -
Glutamate Inhibitors in Glioblastoma
Posted: December 23rd, 2022, 3:00pm GMT
Condition: Glioblastoma
Interventions: Drug: Gabapentin; Drug: Sulfasalazine; Drug: Memantine; Drug: Temozolomide; Radiation: Radiotherapy
Sponsors: University of Zurich; Swiss National Science Foundation
Not yet recruiting -
Assessment of the Presence of Symptoms of End-of-life Discomfort and Their Management in Children With a Primary Brain Tumor in the Grand Est Region Impact of the Development of Pediatric Palliative Care
Posted: December 21st, 2022, 3:00pm GMT
Condition: Primary Brain Tumor
Intervention:
Sponsor: University Hospital, Strasbourg, France
Recruiting -
Cognitive Outcomes After Brain Substructure-informed Radiation Planning in Pediatric Patients
Posted: December 21st, 2022, 3:00pm GMT
Conditions: Brain Tumor; Head and Neck Cancer
Interventions: Radiation: substructure informed planning; Other: Neurocognitive Testing; Diagnostic Test: MRI
Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Not yet recruiting -
Nasal Outcomes Using Saline Irrigations After Endonasal Pituitary Surgery
Posted: December 21st, 2022, 3:00pm GMT
Condition: Pituitary Tumor
Intervention: Other: Nasal saline irrigation
Sponsors: Nicole Hill; Barrow Brain and Spine
Recruiting -
Simultaneous Integrated Boost FDOPA PET Guided in Patients With Partially- or Non-operated Glioblastoma
Posted: December 16th, 2022, 3:00pm GMT
Condition: Glioblastoma Multiforme, Adult
Intervention: Procedure: Integrated boost technique (SIB) guided by PET FDOPA
Sponsor: Institut de cancérologie Strasbourg Europe
Not yet recruiting -
Contribution From PET-DOPA in Glioblastoma Re-irradiation
Posted: December 16th, 2022, 3:00pm GMT
Condition: Glioblastoma
Intervention: Radiation: Simultaneous-integrated boost with IMRT
Sponsors: Institut de cancérologie Strasbourg Europe; Centre Georges François Leclerc
Not yet recruiting -
PCI and Brain MRI Follow-up vs Brain MRI Follow-up Alone in Limited-stage SCLC Patients
Posted: December 15th, 2022, 3:00pm GMT
Condition: Small Cell Lung Cancer Limited Stage
Interventions: Radiation: Prophylactic cranial irradiation; Radiation: Thoracic radiotherapy; Drug: Chemotherapy
Sponsors: Zhejiang Cancer Hospital; Sun Yat-sen University; First Affiliated Hospital, Sun Yat-Sen University
Not yet recruiting -
Pilot Trial of Autologous Tumor Infiltrating Lymphocytes (LN-144) for Patients With Asymptomatic Melanoma Brain Metastases
Posted: December 7th, 2022, 3:00pm GMT
Condition: Metastatic Melanoma
Intervention: Biological: Lifileucel (LN-144)
Sponsors: Memorial Sloan Kettering Cancer Center; Iovance Biotherapeutics, Inc.
Recruiting -
A Window of Opportunity Study of Patritumab Deruxtecan in Patients With Brain Metastases
Posted: November 17th, 2022, 3:00pm GMT
Condition: Brain Metastases, Adult
Intervention: Drug: Patritumab deruxtecan
Sponsors: Mustafa Khasraw, MBChB, MD, FRCP, FRACP; Daiichi Sankyo, Inc.
Not yet recruiting -
Improving Exercise Capacity With a Tailored Physical Activity Intervention
Posted: October 27th, 2022, 2:00pm GMT
Conditions: Non Hodgkin Lymphoma; Heart; Functional Disturbance; Hodgkin Lymphoma; Quality of Life
Interventions: Other: Exercise with Trainerize application; Diagnostic Test: Cardiopulmonary exercise testing; Diagnostic Test: MRI scan; Behavioral: Quality of Life Questionnaires; Behavioral: Cognitive and Brain Function Questionnaires; Other: Blood draws
Sponsors: Wake Forest University Health Sciences; National Cancer Institute (NCI)
Recruiting -
Precision Medicine for Every Child With Cancer
Posted: August 17th, 2022, 2:00pm GMT
Conditions: Childhood Cancer; Childhood Solid Tumor; Childhood Brain Tumor; Childhood Leukemia; Refractory Cancer; Relapsed Cancer
Interventions: Genetic: Whole Genome Sequencing; Genetic: RNA seq; Genetic: DNA Methylation; Genetic: Targeted Panel Sequencing; Genetic: High Throughput Sequencing (in vitro); Genetic: Patient Derived Xenograft (PDX)(in vivo); Other: Liquid Biopsy
Sponsors: Australian & New Zealand Children's Haematology/Oncology Group; Children's Cancer Institute; Minderoo Foundation; Medical Research Future Fund
Recruiting -
Oral AMXT 1501 Dicaprate in Combination With IV DFMO
Posted: August 15th, 2022, 2:00pm GMT
Conditions: Cancer; Solid Tumor; Solid Carcinoma; Advanced Cancer; DIPG Brain Tumor; Ovary Cancer; Breast Cancer; Papillary Thyroid Cancer; Head and Neck Cancer; Gastric Cancer; Nsclc; Mesotheliomas Pleural; Mesothelioma Peritoneum; Esophageal Cancer; Diffuse Midline Glioma, H3 K27M-Mutant; Endometrial Cancer; Cervical Cancer; Melanoma; Colorectal Cancer
Interventions: Drug: AMXT1501; Drug: DFMO
Sponsor: Aminex Therapeutics, Inc.
Recruiting -
Post Market Clinical Follow-Up Study on the Performance and Safety of Lyoplant®
Posted: July 1st, 2022, 2:00pm GMT
Conditions: Tumor, Cerebral Ventricle; Tumor, Cerebellar; Aneurysm Cerebral; Trauma, Brain
Intervention: Device: Lyoplant®
Sponsor: Aesculap AG
Not yet recruiting -
Temporally-modulated Pulsed Radiation Therapy (TMPRT) After Prior EBRT for Recurrent IDH-mutant Gliomas
Posted: May 26th, 2022, 2:00pm GMT
Conditions: Astrocytoma; Oligodendroglioma, Adult; Glioma, Malignant
Intervention: Radiation: temporally-modulated pulsed radiotherapy (TMPRT)
Sponsor: Washington University School of Medicine
Recruiting -
Study of Abemaciclib and Elacestrant in Patients With Brain Metastasis Due to HR+/HER2- Breast Cancer
Posted: May 23rd, 2022, 2:00pm GMT
Conditions: Breast Neoplasms; Brain Neoplasms; Neoplasms by Site; Neoplasms; Breast Diseases; Central Nervous System Neoplasms; Brain Diseases; Central Nervous System Diseases
Interventions: Drug: Elacestrant; Drug: Abemaciclib
Sponsor: Stemline Therapeutics, Inc.
Recruiting -
Blood-Brain Barrier Disruption (BBBD) for Liquid Biopsy in Subjects With GlioBlastoma Brain Tumors
Posted: May 20th, 2022, 2:00pm GMT
Conditions: Glioblastoma; Glioma; Liquid Biopsy
Intervention: Device: Focused Ultrasound (Exablate Model 4000)
Sponsor: InSightec
Recruiting -
Combination Drug Therapy for Personalized Cancer Stem Cell High-Throughput Drug Screening for Glioblastoma
Posted: May 18th, 2022, 2:00pm GMT
Condition: Newly Diagnosed Glioblastoma
Intervention: Drug: combinations of up to 3 FDA approved drugs from a panel of compounds
Sponsor: Swedish Medical Center
Not yet recruiting -
Rare Tumors and Cancer Predisposition in Individuals and Families
Posted: April 28th, 2022, 2:00pm GMT
Conditions: Cancer; Hereditary Neoplasms; Genetic Predisposition to Cancer; Environment
Intervention:
Sponsor: National Cancer Institute (NCI)
Recruiting -
ETAPA I: Peptide-based Tumor Associated Antigen Vaccine in GBM
Posted: March 16th, 2022, 2:00pm GMT
Condition: Glioma, Malignant
Interventions: Biological: Tumor Associated Antigen Peptide Vaccine P30-EPS Vaccine; Drug: Hiltonol
Sponsors: Mustafa Khasraw, MBChB, MD, FRCP, FRACP; National Cancer Institute (NCI)
Not yet recruiting -
WBSI Guided Personalized Delivery of TTFields
Posted: October 21st, 2021, 2:00pm GMT
Conditions: GBM; Glioma Glioblastoma Multiforme; Tumor, Brain
Intervention: Diagnostic Test: Whole Brain Spectroscopy Imaging Array Mapping Layout
Sponsors: Abramson Cancer Center of the University of Pennsylvania; NovoCure Ltd.; National Institutes of Health (NIH); National Cancer Institute (NCI)
Recruiting -
Intra-Arterial Chemotherapy for Newly Diagnosed, Residual, or Recurrent Atypical Choroid Plexus Papilloma and Choroid Plexus Carcinoma Prior to Second-Look Surgery
Posted: August 6th, 2021, 2:00pm GMT
Conditions: Atypical Choroid Plexus Papilloma; Choroid Plexus Carcinoma
Interventions: Drug: Melphalan; Drug: Carboplatin; Drug: Topotecan
Sponsor: Weill Medical College of Cornell University
Recruiting -
Patient Perceptions Around Quality of Care Through Telemedicine in Neuro-Oncology
Posted: August 3rd, 2021, 2:00pm GMT
Conditions: Central Nervous System Neoplasm; Leptomeningeal Neoplasm; Metastatic Malignant Neoplasm in the Brain; Primary Brain Neoplasm
Interventions: Other: Electronic Health Record Review; Other: Survey Administration
Sponsor: M.D. Anderson Cancer Center
Recruiting -
Trial of Anti-PD-1 Immunotherapy and Stereotactic Radiation in Patients With Recurrent Glioblastoma
Posted: July 26th, 2021, 2:00pm GMT
Condition: Glioblastoma Multiforme
Interventions: Drug: Pembrolizumab; Radiation: Stereotactic Radiation Therapy; Procedure: Surgical Resection
Sponsors: Chirag G. Patil; Merck Sharp & Dohme LLC; National Cancer Institute (NCI)
Recruiting -
Cognitive Changes of IDH-mutant and IDH-wildtype Glioma Patients After Chemoradiotherapy With Radiation Dose to the Resting State Networks
Posted: July 23rd, 2021, 2:00pm GMT
Condition: Glioma
Intervention: Device: RS-fMRI
Sponsors: Washington University School of Medicine; The Foundation for Barnes-Jewish Hospital
Recruiting -
A Safety Study of Pharmacologic Ascorbate and Ferumoxytol in Addition to Standard of Care Chemoradiation in Glioblastoma
Posted: May 25th, 2021, 2:00pm GMT
Conditions: Glioblastoma; Glioblastoma Multiforme
Interventions: Drug: Ferumoxytol injection; Drug: Pharmacological ascorbate; Radiation: External beam radiation therapy; Drug: Temozolomide
Sponsors: Bryan Allen; Holden Comprehensive Cancer Center; National Cancer Institute (NCI)
Not yet recruiting -
WHOle Brain Irradiation or STEreotactic Radiosurgery for Five or More Brain Metastases (WHOBI-STER)
Posted: May 18th, 2021, 2:00pm GMT
Conditions: Neurocognitive Deficit; Quality of Life; Activities of Daily Living
Interventions: Radiation: Stereotactic RadioTherapy; Radiation: Whole Brain Irradiation
Sponsors: Mediterranean Institute of Oncology; University of Messina; University of Palermo
Recruiting -
Surgical Resection of Latent Brain Tumors Prior to Recurrence
Posted: March 23rd, 2021, 2:00pm GMT
Condition: Brain Neoplasm
Intervention: Procedure: Brain Surgery
Sponsors: Mayo Clinic; National Cancer Institute (NCI)
Recruiting -
Pilot Study to Investigate Magnetic Resonance (MR) Image Guided Focal Therapy in Prostate Cancer
Posted: March 22nd, 2021, 2:00pm GMT
Condition: Prostate Cancer
Intervention: Device: TULSA-PRO
Sponsor: National Cancer Institute (NCI)
Not yet recruiting -
Monocyte Antigen Carrier Cells for Newly Diagnosed GBM
Posted: February 5th, 2021, 3:00pm GMT
Conditions: Glioblastoma; Glioma, Malignant
Intervention: Biological: MT-201-GBM monocyte vaccine
Sponsors: Michael Gunn; National Cancer Institute (NCI)
Not yet recruiting -
TumorGlow Intraoperative Molecular Imaging (IMI)
Posted: January 26th, 2021, 3:00pm GMT
Condition: Tumor, Solid
Intervention: Drug: Indocyanine Green
Sponsor: University of Pennsylvania
Not yet recruiting -
Postoperative Risk Prediction Score After Elective Intracranial Neurosurgery Operation
Posted: October 14th, 2020, 2:00pm GMT
Conditions: Brain Tumor; Post-Op Complication; Anesthesia
Interventions: Other: Quality of Recovery-15; Other: Glasgow Result Scale; Other: Risk Factors
Sponsor: Trakya University
Recruiting -
A Study to Compare the Administration of Encorafenib + Binimetinib + Nivolumab Versus Ipilimumab + Nivolumab in BRAF-V600 Mutant Melanoma With Brain Metastases
Posted: August 12th, 2020, 2:00pm GMT
Conditions: Acral Lentiginous Melanoma; Clinical Stage IV Cutaneous Melanoma AJCC v8; Metastatic Cutaneous Melanoma; Metastatic Malignant Neoplasm in the Brain; Metastatic Melanoma; Metastatic Mucosal Melanoma; Pathologic Stage IV Cutaneous Melanoma AJCC v8
Interventions: Drug: Binimetinib; Drug: Encorafenib; Biological: Ipilimumab; Biological: Nivolumab
Sponsors: Southwest Oncology Group; National Cancer Institute (NCI)
Recruiting -
Pre- Versus Post-operative SRS for Resectable Brain Metastases
Posted: July 17th, 2020, 2:00pm GMT
Condition: Brain Metastases
Interventions: Procedure: Brain Surgery; Radiation: Stereotactic Radiosurgery
Sponsor: AHS Cancer Control Alberta
Recruiting -
Quality Improvement Project - "My Logbook! - I Know my Way Around!"; ("Mein Logbuch - Ich Kenne Mich Aus!")
Posted: July 17th, 2020, 2:00pm GMT
Conditions: Brain Tumor; Neurofibromatoses; Sarcoma; Leukemia; Hematologic Diseases; Neuroblastoma
Intervention: Other: "My Logbook! - I know my way around!"
Sponsors: Medical University of Vienna; St. Anna Kinderspital, Austria; Charite University, Berlin, Germany; Cnopfsche Kinderklinik, Nürnberg; Kepler University Hospital; University Hospital, Saarland; Hannover Medical School; Krankenhaus Bozen; University Hospital Frankfurt; Universitätsklinikum Hamburg-Eppendorf; Universitätsklinikum Leipzig; University Hospital Muenster; University Hospital Tuebingen; Salzburger Landeskliniken; Leuwaldhof St.Veit (Kinder- und Jugendreha); University Hospital, Essen; Medical University of Graz; University Hospital Erlangen; Wuerzburg University Hospital; Klinik Bad Oexen, Germany; Universitätsklinikum Köln; University Hospital Schleswig-Holstein; University Hospital Carl Gustav Carus; Universitätsmedizin Mannheim; University Hospital Regensburg; Luca-Dethlefsen-Hilfe e.V.; University Hospital Inselspital, Berne; Staedtisches Klinikum Karlsruhe
Recruiting -
Prospective Evaluation of High Resolution Dual Energy Computed Tomographic Imaging, Noninvasive (Liquid) Biopsies, and Minimally Invasive Surgical Surveillance for Early Detection of Mesotheliomas in Patients With BAP1 Tumor Predisposition Syndrome
Posted: June 16th, 2020, 2:00pm GMT
Conditions: Familial Cancer; BRCA1-Associated Protein-1 (BAP1) Mutations; Tumor Predisposition Syndrome (TPDS); Mesothelioma
Intervention:
Sponsor: National Cancer Institute (NCI)
Recruiting -
Dose Finding for Intraoperative Photodynamic Therapy of Glioblastoma
Posted: May 18th, 2020, 2:00pm GMT
Condition: Glioblastoma
Interventions: Drug: Gliolan; Device: Intraoperative PDT
Sponsors: University Hospital, Lille; Institut National de la Santé Et de la Recherche Médicale, France; Hemerion Therapeutics
Recruiting -
Dendritic Cell Vaccines Against Her2/Her3 and Pembrolizumab for the Treatment of Brain Metastasis From Triple Negative Breast Cancer or HER2+ Breast Cancer
Posted: April 16th, 2020, 2:00pm GMT
Conditions: Anatomic Stage IV Breast Cancer AJCC v8; Metastatic Malignant Neoplasm in the Brain; Metastatic Triple-Negative Breast Carcinoma; Prognostic Stage IV Breast Cancer AJCC v8
Interventions: Biological: Anti-HER2/HER3 Dendritic Cell Vaccine; Biological: Pembrolizumab
Sponsors: Roswell Park Cancer Institute; United States Department of Defense
Recruiting -
Electronic Social Network Assessment Program (eSNAP) + Caregiver Navigator
Posted: February 13th, 2020, 3:00pm GMT
Condition: Brain Cancer
Interventions: Behavioral: eSNAP; Behavioral: Caregiver Navigator
Sponsor: H. Lee Moffitt Cancer Center and Research Institute
Recruiting -
A Brain Metastases Research Platform to Tackle the Challenge of CNS Metastases in Solid Tumours
Posted: September 30th, 2019, 2:00pm GMT
Condition: CNS Metastases
Interventions: Other: Samples collection: Plasma; Other: Samples collection: CSF; Other: Samples collection: Non-CNS Metastatic Tumour Tissue; Other: Brain MRI; Other: Samples collection: Serum
Sponsors: Jules Bordet Institute; La Fondation contre le cancer, Belgique; Les Amis de l'Institut Bordet; Bristol-Myers Squibb; Fondation Cancer, Luxembourg
Recruiting -
C7R-GD2.CAR T Cells for Patients With GD2-expressing Brain Tumors (GAIL-B)
Posted: September 23rd, 2019, 2:00pm GMT
Conditions: Diffuse Intrinsic Pontine Glioma; High Grade Glioma; Embryonal Tumor; Ependymal Tumor
Interventions: Genetic: (C7R)-GD2.CART cells; Drug: Cyclophosphamide; Drug: Fludarabine
Sponsors: Baylor College of Medicine; Center for Cell and Gene Therapy, Baylor College of Medicine; The Faris Foundation
Recruiting -
Pre-operative SRS or Post-operative SRS in Treating Cancer Patients With Brain Metastases
Posted: November 15th, 2018, 3:00pm GMT
Conditions: Malignant Neoplasm; Metastatic Malignant Neoplasm in the Brain
Interventions: Other: Quality-of-Life Assessment; Other: Questionnaire Administration; Radiation: Stereotactic Radiosurgery
Sponsors: M.D. Anderson Cancer Center; National Cancer Institute (NCI)
Recruiting -
Feasibility of Endosphenoidal Coil Placement for Imaging of the Sella During Transsphenoidal Surgery
Posted: September 19th, 2018, 2:00pm GMT
Condition: Pituitary Neoplasm
Intervention: Other: ESC
Sponsor: National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting -
A Study to Assess the Safety and Tolerability of AZD1390 Given With Radiation Therapy in Patients With Brain Cancer
Posted: February 6th, 2018, 3:00pm GMT
Conditions: Recurrent Glioblastoma Multiforme; Primary Glioblastoma Multiforme; Brain Neoplasms, Malignant; Leptomeningeal Disease (LMD)
Interventions: Radiation: Radiation Therapy; Drug: AZD1390
Sponsor: AstraZeneca
Recruiting -
Evaluation of the Efficacy and Safety of Nal-IRI for Progressing Brain Metastases in Breast Cancer Patients
Posted: November 1st, 2017, 2:00pm GMT
Condition: Breast Cancer Metastatic
Intervention: Drug: Irinotecan Hydrochloride
Sponsor: MedSIR
Recruiting -
Laser Interstitial Thermotherapy (LITT) Combined With Checkpoint Inhibitor for Recurrent GBM (RGBM)
Posted: September 11th, 2017, 2:00pm GMT
Condition: Glioblastoma, Adult
Interventions: Drug: Pembrolizumab at 7 days prior; Drug: Pembrolizumab at 14 days post; Drug: Pembrolizumab at 35 days post; Procedure: Laser Interstitial Thermotherapy
Sponsor: Case Comprehensive Cancer Center
Recruiting -
Ion Therapy Patient Registry
Posted: February 9th, 2017, 3:00pm GMT
Condition: Ion Beam Radiation Therapy for Tumor Patients
Intervention: Radiation: Protons and Carbon Ions
Sponsor: EBG MedAustron GmbH
Recruiting -
Abemaciclib in Children With DIPG or Recurrent/Refractory Solid Tumors
Posted: December 31st, 2015, 3:00pm GMT
Conditions: Diffuse Intrinsic Pontine Glioma; Brain Tumor, Recurrent; Solid Tumor, Recurrent; Neuroblastoma, Recurrent, Refractory; Ewing Sarcoma, Recurrent, Refractory; Rhabdomyosarcoma, Recurrent, Refractory; Osteosarcoma, Recurrent, Refractory; Rhabdoid Tumor, Recurrent, Refractory
Intervention: Drug: Abemaciclib
Sponsor: Emory University
Recruiting -
Dopamine Agonist Treatment of Non-functioning Pituitary Adenomas
Posted: November 13th, 2014, 3:00pm GMT
Conditions: Pituitary Neoplasms; Adenoma
Intervention: Drug: cabergoline
Sponsors: St. Olavs Hospital; Norwegian University of Science and Technology
Recruiting