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Permalink for 'A Modified Dose of Rabbit Anti-thymocyte Globulin (rATG) in Children and Adults Receiving Treatment to Help Prepare Their Bodies for a Bone Marrow Transplant'

A Modified Dose of Rabbit Anti-thymocyte Globulin (rATG) in Children and Adults Receiving Treatment to Help Prepare Their Bodies for a Bone Marrow Transplant

Posted: May 4th, 2021, 2:00pm GMT

Conditions: Acute Myeloid Leukemia (AML); Acute Lymphoid Leukemia (ALL); Myelodysplastic Syndromes (MDS)
Interventions: Other: Personalized rATG (P-rATG); Radiation: Hyper fractionated total body irradiation; Drug: Thiotepa; Drug: Cyclophosphamide; Drug: GCSF; Drug: Busulfan; Drug: Melphalan; Drug: Fludarabine
Sponsor: Memorial Sloan Kettering Cancer Center
Recruiting

Permalink for 'Individualized Response Assessment to Heated Intraperitoneal Chemotherapy (HIPEC) for the Treatment of Peritoneal Carcinomatosis From Ovarian, Colorectal, Appendiceal, or Peritoneal Mesothelioma Histologies'

Individualized Response Assessment to Heated Intraperitoneal Chemotherapy (HIPEC) for the Treatment of Peritoneal Carcinomatosis From Ovarian, Colorectal, Appendiceal, or Peritoneal Mesothelioma Histologies

Posted: April 15th, 2021, 2:00pm GMT

Conditions: Peritoneal Carcinomatosis; Peritoneal Mesothelioma; Ovarian Cancer; Gastrointestinal Cancer; Appendiceal Cancer
Interventions: Drug: Mitomycin C; Drug: Cisplatin; Procedure: Heated Intraperitonial Chemotherapy; Drug: Doxorubicin; Drug: Oxaliplatin; Drug: 5-Fluorouracil; Drug: Sodium Thiosulfate
Sponsor: National Cancer Institute (NCI)
Not yet recruiting

Full-thickness Laparo-endoscopic Excision vs Laparoscopic Resection of Colon Tumors

Posted: March 17th, 2021, 2:00pm GMT

Condition: Colorectal Neoplasms, Benign
Interventions: Procedure: full-thickness laparo-endoscopic colon adenomas excision; Procedure: laparoscopic colon resection
Sponsor: State Scientific Centre of Coloproctology, Russian Federation
Recruiting

Flat Dose vs. Weight-based IP Chemotherapy for CRS/HIPEC

Posted: March 3rd, 2021, 3:00pm GMT

Condition: Peritoneal Carcinomatosis
Interventions: Drug: Mitomycin C, flat dose 40 mg; Drug: Mitomycin C, weight-based dose 12.5 mg/m2
Sponsor: Prakash Pandalai
Recruiting

Improving Cancer Outcomes Through Personalized Care Planning and Symptom Management.

Posted: February 26th, 2021, 3:00pm GMT

Conditions: Lung Cancer; Breast Cancer; Gynecologic Cancer
Intervention: Other: Carevive PROmpt™
Sponsor: Carevive Systems, Inc.
Not yet recruiting

Permalink for 'LUMINOS-103: A Basket Trial Evaluating the Safety and Efficacy of PVSRIPO and PVSRIPO in Combination With Anti-PD-1/L1 Checkpoint Inhibitors in Patients With Advanced Solid Tumors'

LUMINOS-103: A Basket Trial Evaluating the Safety and Efficacy of PVSRIPO and PVSRIPO in Combination With Anti-PD-1/L1 Checkpoint Inhibitors in Patients With Advanced Solid Tumors

Posted: December 31st, 2020, 3:00pm GMT

Conditions: Solid Tumor; Bladder Cancer
Interventions: Biological: PVSRIPO; Biological: Anti-PD-1 / L1
Sponsor: Istari Oncology, Inc.
Not yet recruiting

Anti-PD1-antibody and Pulsed HHI for Advanced BCC

Posted: December 22nd, 2020, 3:00pm GMT

Condition: Basal Cell Carcinoma
Intervention: Drug: Cemiplimab Injection [Libtayo]
Sponsors: Reinhard Dummer; Sanofi; Sun Pharmaceutical Industries Ltd
Recruiting

Afatinib in Advanced NRG1-Rearranged Malignancies

Posted: June 1st, 2020, 2:00pm GMT

Condition: Metastatic and Locally Advanced NRG1-rearranged Malignancies
Intervention: Drug: Afatinib 40 MG
Sponsors: German Cancer Research Center; German Consortium for Translational Cancer Research
Not yet recruiting

The Registry of Oncology Outcomes Associated With Testing and Treatment

Posted: July 22nd, 2019, 2:00pm GMT

Conditions: Adenocarcinoma; Adenocystic Carcinoma; Anal Cancer; Appendix Cancer; Brain Tumor; Glioblastoma; Astrocytoma; Bile Duct Cancer; Cholangiocarcinoma; Bladder Cancer; Bone Cancer; Synovial Sarcoma; Chondrosarcoma; Liposarcoma; Sarcoma, Kaposi; Sarcoma,Soft Tissue; Sarcoma; Osteosarcoma; CNS Cancer; Brain Stem Neoplasms; Breast Cancer; Cervical Cancer; Colorectal Cancer; Rectal Cancer; Colon Cancer; Esophageal Cancer; Esophagus Cancer; Cancer of Colon; Pancreatic Cancer; Cancer of Pancreas; Testis Cancer; Testicular Cancer; Ureter Cancer; Renal Cell Carcinoma; Kidney Cancer; Gestational Trophoblastic Tumor; Head and Neck Neoplasms; Parotid Tumor; Larynx Cancer; Tongue Cancer; Pharynx Cancer; Salivary Gland Cancer; Acute Myeloid Leukemia; Chronic Myeloid Leukemia; Acute Lymphoblastic Leukemia; Multiple Myeloma; Non Hodgkin Lymphoma; Carcinoid Tumor; Lung Cancer; Neuroendocrine Tumors; Mesothelioma; Thyroid Cancer; Parathyroid Neoplasms; Adrenal Cancer; Small Bowel Cancer; Stomach Cancer; Liver Cancer; Hepatic Cancer; Melanoma; Skin Cancer; Unknown Primary Tumors; Uterine Cancer; Fallopian Tube Cancer; Ovarian Cancer; Prostate Cancer; Vaginal Cancer; Penile Cancer; Vulvar Cancer; Waldenstrom Macroglobulinemia; Cancer, Advanced; Thymus Cancer; Nasopharyngeal Carcinoma; Multiple Endocrine Neoplasia; Pheochromocytoma; Small Cell Carcinoma; Pulmonary Carcinoma
Interventions: Diagnostic Test: Biomarker Testing (L); Drug: Systemic Treatment (T); Other: Patient Reported Outcomes (P)
Sponsor: Taproot Health
Not yet recruiting

Myeloma XIV: Frailty-adjusted Therapy in Transplant Non-Eligible Patients With Newly Diagnosed Multiple Myeloma

Posted: October 25th, 2018, 2:00pm GMT

Condition: Multiple Myeloma
Interventions: Drug: R1: Ixazomib, Lenalidomide, Dexamethasone (IRD) induction therapy - reactive arm; Drug: R1: Ixazomib, Lenalidomide, Dexamethasone (IRD) induction therapy - adaptive arm; Drug: R2: Lenalidomide plus placebo maintenance; Drug: R2: Lenalidomide + ixazomib maintenance
Sponsors: University of Leeds; Cancer Research UK; Takeda; Celgene
Recruiting

A Study of Carboplatin and Paclitaxel Chemotherapy With Nivolumab With or Without Ipilimumab in Patients With Ovarian Cancer

Posted: August 10th, 2017, 2:00pm GMT

Conditions: High Grade Serous Ovarian; Fallopian Tube; Primary Peritoneal Cancer
Interventions: Drug: Carboplatin and Paclitaxel; Drug: Nivolumab; Procedure: Cytoreductive surgery; Drug: Ipilimumab
Sponsors: Memorial Sloan Kettering Cancer Center; Bristol-Myers Squibb
Recruiting

Prevention of Irinotecan Induced Diarrhea by Probiotics

Posted: June 30th, 2016, 2:00pm GMT

Conditions: Diarrhea; Cancer
Interventions: Drug: PROBIO-FIX INUM®; Drug: Placebo
Sponsors: S&D Pharma SK s.r.o.; National Cancer Institute, Slovakia
Recruiting

18F-MFBG Imaging for Evaluation of Neuroendocrine Malignancies

Posted: January 28th, 2015, 3:00pm GMT

Condition: Neuroendocrine Tumors
Interventions: Radiation: 18F-MFBG (meta-fluoro benzylguanidine); Device: Positron emission tomography (PET) imaging; Other: Blood draws
Sponsor: Memorial Sloan Kettering Cancer Center
Recruiting

Development of Psychotherapeutic Interventions for Parents Who Lost a Child

Posted: June 3rd, 2014, 2:00pm GMT

Condition: Parents Who Have Lost a Child
Interventions: Behavioral: Meaning-Centered Grief Therapy (MCGT); Behavioral: Supportive Psychotherapy (SP); Behavioral: questionnaires assessments
Sponsors: Memorial Sloan Kettering Cancer Center; University of Memphis; University of Hawaii; Adelphi University; Weill Medical College of Cornell University; University of Southern California; The New School for Social Research; Monash University
Recruiting

Electronic Skin Surface Brachytherapy for Cutaneous Basal Cell and Squamous Cell Carcinoma

Posted: May 6th, 2014, 2:00pm GMT

Conditions: Cutaneous Basal Cell; Squamous Cell Carcinoma
Interventions: Radiation: Electronic Skin Surface Brachytherapy; Behavioral: Quality of life assessment
Sponsors: Memorial Sloan Kettering Cancer Center; Lynn Cancer Institute
Recruiting

Permalink for 'ICARuS Post-operative Intraperitoneal Chemotherapy (EPIC) and Hyperthermic Intraperitoneal Chemotherapy (HIPEC) After Optimal Cytoreductive Surgery (CRS) for Neoplasms of the Appendix, Colon or Rectum With Isolated Peritoneal Metastasis'

ICARuS Post-operative Intraperitoneal Chemotherapy (EPIC) and Hyperthermic Intraperitoneal Chemotherapy (HIPEC) After Optimal Cytoreductive Surgery (CRS) for Neoplasms of the Appendix, Colon or Rectum With Isolated Peritoneal Metastasis

Posted: March 21st, 2013, 2:00pm GMT

Conditions: Appendix Cancer; Colorectal Cancer
Interventions: Procedure: Cytoreductive Surgery; Drug: HIPEC with Mitomycin-C; Drug: EPIC with FUDR and Leucovorin
Sponsors: Memorial Sloan Kettering Cancer Center; The Cleveland Clinic; Brigham and Women's Hospital; University of Miami; University of Pittsburgh Medical Center; Washington University School of Medicine
Recruiting

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Trial - Appendix Cancer (16 unread)