Rare Cancer News & Clinical Trials » Trial

Therapy Adapted for High Risk and Low Risk HIV-Associated Anal Cancer

Posted: June 17th, 2021, 2:00pm GMT

Conditions: AIDS-Related Anal Carcinoma; Anal Basaloid Carcinoma; Anal Canal Cloacogenic Carcinoma; Anal Squamous Cell Carcinoma; HIV Infection; Rectal Squamous Cell Carcinoma; Stage I Anal Cancer AJCC v8; Stage II Anal Cancer AJCC v8; Stage IIA Anal Cancer AJCC v8; Stage IIB Anal Cancer AJCC v8; Stage III Anal Cancer AJCC v8; Stage IIIA Anal Cancer AJCC v8; Stage IIIB Anal Cancer AJCC v8; Stage IIIC Anal Cancer AJCC v8
Interventions: Drug: Capecitabine; Drug: Fluorouracil; Radiation: Intensity-Modulated Radiation Therapy; Drug: Mitomycin; Biological: Nivolumab
Sponsor: National Cancer Institute (NCI)
Not yet recruiting

Neoadjuvant Chemoradiotherapy Plus Tislelizumab Followed by TME for LARC.

Posted: June 3rd, 2021, 2:00pm GMT

Condition: Colorectal Neoplasms
Intervention: Combination Product: long course radiotherapy + capecitabine + PD-1 monoclonal antibody treatment combinations
Sponsors: Beijing Friendship Hospital; Hangzhou New Horizon Health Technology Co., Ltd.; Beigene (Beijing) Biotechnology Co., Ltd; Beijing Chao Yang Hospital; Xuanwu Hospital, Beijing; Tianjin Medical University General Hospital; People's Hospital of Tianjin; Tianjin Medical University Cancer Institute & Hospital; China-Japan Friendship Hospital
Not yet recruiting

Permalink for 'Prevalence and Longitudinal Follow-up of Anal Lesions, HPV Infection and Associated Sexually Transmitted Infections Among Men Who Have Sex With Men in Togo.'

Prevalence and Longitudinal Follow-up of Anal Lesions, HPV Infection and Associated Sexually Transmitted Infections Among Men Who Have Sex With Men in Togo.

Posted: June 2nd, 2021, 2:00pm GMT

Conditions: Papillomavirus Infections; HIV Infections
Intervention: Other: STIs screening and care
Sponsors: ANRS, Emerging Infectious Diseases; Université de Lomé, Département de Santé Publique, Lomé, Togo; Bichat Hospital; Espoir Vie-Togo - ONG; Centre Africain de Recherche en Epidémiologie et en Santé Publique, Lomé, Togo; Programme PAC-CI, Site ANRS-MIE de Côte d'Ivoire; Laboratoire de Biologie Moléculaire et d'Immunologie, Lomé, Togo; Saint-Louis Hospital, Paris, France; University Hospital, Bordeaux
Not yet recruiting

Permalink for 'Impact of Specific Monitoring of Intraoperative Analgesia Under General Anesthesia on Chronic Pain After Ovarian Cancer Surgery'

Impact of Specific Monitoring of Intraoperative Analgesia Under General Anesthesia on Chronic Pain After Ovarian Cancer Surgery

Posted: May 28th, 2021, 2:00pm GMT

Condition: Ovarian Neoplasm
Interventions: Other: Arm A : intraoperative ANI monitoring of nociception; Other: Arm B : no specific monitoring of nociception
Sponsor: Institut Bergonié
Not yet recruiting

Pomalidomide and Nivolumab in People With Virus-Associated Malignancies With or Without HIV

Posted: May 26th, 2021, 2:00pm GMT

Conditions: Viral Associated Malignancies; Kaposi Sarcoma; EBV/KSHV-associated Lymphomas
Interventions: Drug: Pomalidomide; Drug: Nivolumab
Sponsor: National Cancer Institute (NCI)
Not yet recruiting

Multi-site HPV Screening by High-throughput Sequencing in Patients With Chronic HPV-HR Infection Followed by Gynecology

Posted: May 25th, 2021, 2:00pm GMT

Condition: Human Papillomavirus
Intervention: Procedure: Smear
Sponsor: University Hospital, Toulouse
Not yet recruiting

Combination of Spartalizumab, mDCF and Radiotherapy in Patients With Metastatic Squamous Cell Anal Carcinoma

Posted: May 20th, 2021, 2:00pm GMT

Conditions: Squamous Cell Anal Carcinoma; Metastatic Squamous Cell Carcinoma
Intervention: Biological: Sample collection
Sponsors: Centre Hospitalier Universitaire de Besancon; National Cancer Institute, France; Novartis
Not yet recruiting

Study of SQZ-AAC-HPV in Patients With HPV16+ Recurrent, Locally Advanced or Metastatic Solid Tumors

Posted: May 19th, 2021, 2:00pm GMT

Condition: Adult Solid Tumor
Interventions: Biological: SQZ-AAC-HPV; Drug: Ipilimumab; Drug: Nivolumab
Sponsor: SQZ Biotechnologies
Not yet recruiting

Hyperthermia Enhanced Re-irradiation of Loco-regional Recurrent Tumors

Posted: May 17th, 2021, 2:00pm GMT

Conditions: Recurrent Cancer; Prostate Cancer; Cervical Cancer; Anal Cancer; Sarcoma; Rectal Cancer; Neuroendocrine Tumors; Esophageal Cancer; Pancreas Cancer; Squamous Cell Carcinoma
Intervention: Device: loco-regional hyperthermia
Sponsor: Charite University, Berlin, Germany
Recruiting

Detecting HPV DNA in Anal and Cervical Cancers

Posted: April 23rd, 2021, 2:00pm GMT

Conditions: Cervical Cancer; Anal Cancer; HPV-Related Anal Squamous Cell Carcinoma; HPV-Related Cervical Carcinoma; HPV-Related Carcinoma; Uterine Cervical Cancer
Interventions: Radiation: Radiation Treatment With or Without Chemotherapy; Other: Blood Sample Collection; Diagnostic Test: HPV Genotyping (HPV DNA Test); Diagnostic Test: Testing Archival Tumor Tissue; Other: Physical Exam; Diagnostic Test: Positron Emission Tomography Scan (PET Scan)/ Computed Tomography Scan (CT Scan)
Sponsor: University of Chicago
Recruiting

An Online Intervention Promoting HPV Vaccination Among Chinese MSM

Posted: March 25th, 2021, 2:00pm GMT

Condition: Vaccine Refusal
Intervention: Behavioral: Intervention
Sponsor: Chinese University of Hong Kong
Recruiting

Role of Neoadjuvent Radiotherapy in Locally Advanced Cancer Rectum

Posted: March 24th, 2021, 2:00pm GMT

Condition: Rectal Adenocarcinoma
Intervention: Radiation: Neoadjuvent radiotherapy either short or long course chemoradiation in treatment of locally advanced cancer rectum
Sponsor: Amany sayed Abass
Not yet recruiting

Efficacy of Spartalizumab Across Multiple Cancer-types in Patients With PD1-high mRNA Expressing Tumors

Posted: March 17th, 2021, 2:00pm GMT

Conditions: MSI-H Colorectal Cancer; Melanoma; Anal Carcinoma; Mesothelioma; Triple Negative Breast Cancer; Lung Adenocarcinoma; Cholangiocarcinoma; Cervical Carcinoma; Kidney Clear Cell Carcinoma; Stomach Adenocarcinoma; Esophageal Adenocarcinoma; Uterine Endometrial Carcinoma; Head and Neck Squamous Cell Carcinoma; Sarcoma; Lung Squamous Cell Carcinoma; Bladder Carcinoma; Thyroid Carcinoma; Hepatocellular Carcinoma; Uveal Melanoma; HER2-positive Breast Cancer; Pancreatic Adenocarcinoma; Squamous Esophageal Carcinoma; Ovarian Serous Cystadenocarcinoma; Uterine Carcinosarcoma; Small Cell Lung Cancer; Hormone Receptor Positive / HER2-negative Breast Cancer; Lung Adenocarcinoma EGFR-mutated/ ALK Traslocation; Colorectal Adenocarcinoma; Prostate Adenocarcinoma; Carcinoma of Unknown Primary; Other Histology
Intervention: Drug: Spartalizumab
Sponsors: SOLTI Breast Cancer Research Group; Novartis
Recruiting

ANCA II - Quality of Life and Functional Outcome in Patients With Anal Cancer

Posted: March 11th, 2021, 3:00pm GMT

Condition: Anal Cancer
Intervention: Other: Questionnaires
Sponsor: Sahlgrenska University Hospital, Sweden
Not yet recruiting

Diverting Ileostomy and Anal Functional Outcomes After Anus Preservation Surgery

Posted: March 1st, 2021, 3:00pm GMT

Conditions: Diverting Ileostomy; Middle and Low Rectal Cancer; Functional Outcome; Stoma Complications
Intervention: Procedure: Diverting ileostomy
Sponsor: The First Hospital of Jilin University
Not yet recruiting

Anal Dilatation Plus Probiotics Before Ileostomy Reduction for Low Anterior Resection Syndrome

Posted: December 29th, 2020, 3:00pm GMT

Condition: Low Anterior Resection Syndrome
Interventions: Other: Anal dilatation per anus; Drug: administration of probiotics (Clostridium butyricum TO-A; Bacillus mesentericus TO-A; Streptococcus faecalisT-110) per anus
Sponsor: Sixth Affiliated Hospital, Sun Yat-sen University
Recruiting

RTX-321 Monotherapy in Patients With HPV 16+ Tumors

Posted: December 17th, 2020, 3:00pm GMT

Conditions: Cervical Cancer; Head and Neck Cancer; Anal Cancer
Intervention: Drug: RTX-321
Sponsor: Rubius Therapeutics
Recruiting

Watch and Wait in PD-1 Monoclonal Antibody Treated dMMR/MSI-H Distal Rectal Cancer

Posted: November 24th, 2020, 3:00pm GMT

Condition: Rectal Cancer
Intervention: Behavioral: watch and wait
Sponsor: Sixth Affiliated Hospital, Sun Yat-sen University
Recruiting

Permalink for 'Carboplatin-paclitaxel With Retifanlimab or Placebo in Participants With Locally Advanced or Metastatic Squamous Cell Anal Carcinoma (POD1UM-303/InterAACT 2).'

Carboplatin-paclitaxel With Retifanlimab or Placebo in Participants With Locally Advanced or Metastatic Squamous Cell Anal Carcinoma (POD1UM-303/InterAACT 2).

Posted: July 15th, 2020, 2:00pm GMT

Condition: Squamous Cell Carcinoma of the Anal Canal
Interventions: Drug: carboplatin; Drug: paclitaxel; Drug: retifanlimab
Sponsor: Incyte Corporation
Recruiting

Provider-Focused Intervention for Maximizing HPV Vaccine Uptake in Young Cancer Survivors

Posted: July 14th, 2020, 2:00pm GMT

Condition: Papillomavirus Vaccines
Intervention: Behavioral: HPV-PROTECT
Sponsors: University of Alabama at Birmingham; National Cancer Institute (NCI)
Recruiting

Proton Versus Photon Therapy in Anal Squamous Cell Carcinoma

Posted: July 8th, 2020, 2:00pm GMT

Condition: Anal Cancer Squamous Cell
Interventions: Radiation: Proton radiotherapy; Radiation: Photon radiotherapy
Sponsors: Umeå University; Västerbotten County Council
Recruiting

Efficacy of Immunotherapy Plus a Drug in Patients With Progressive Advanced Mucosal Cancer of Different Locations

Posted: April 22nd, 2020, 2:00pm GMT

Conditions: Squamous Cell Lung Cancer; Vulvar Cancer; Penile Cancer; Cervix Cancer; Head and Neck Squamous Cell Carcinoma; Anal Cancer
Intervention: Drug: pembrolizumab; vorinostat
Sponsors: UNICANCER; Merck Sharp & Dohme Corp.; Fondation ARC; ERA-NET
Recruiting

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INCB099318 in Participants With Advanced Solid Tumors

Posted: February 17th, 2020, 3:00pm GMT

Conditions: Advanced Solid Tumors; MSI-H/dMMR Tumors; Cutaneous Squamous Cell Carcinoma; Urothelial Carcinoma, HCC; Cervical Cancer; Esophageal Squamous Cell Carcinoma; Merkel Cell Carcinoma; Small-cell Lung Cancer; Mesothelioma; PD-L1 Amplified Tumor (9p24.1); Nasopharyngeal Carcinoma; Cyclin-dependent Kinase 12 Mutated Tumors; Basal Cell Carcinoma (Unresectable or Metastatic); Sarcomatoid Renal Cell Carcinoma; Clear Cell Ovarian or Endometrial Carcinoma; Anal Carcinoma; Squamous Cell Penile Carcinoma; DNA Polymerase Epsilon Mutated Tumors (P286R and V411L)
Intervention: Drug: INCB099318
Sponsor: Incyte Corporation
Recruiting

Study of SO-C101 and SO-C101 in Combination With Pembro in Adult Patients With Advanced/Metastatic Solid Tumors

Posted: January 21st, 2020, 3:00pm GMT

Conditions: Thyroid; Renal Cell Carcinoma; Non Small Cell Lung Cancer; Small-cell Lung Cancer; Bladder Cancer; Melanoma; Merkel Cell Carcinoma; Skin Squamous Cell Carcinoma; Microsatellite Instability High; Triple Negative Breast Cancer; Mesothelioma; Thymic Cancer; Cervical Cancer; Biliary Tract Cancer; Hepatocellular Carcinoma; Ovarian Cancer; Gastric Cancer; Head and Neck Squamous Cell Carcinoma; Anal Cancer
Interventions: Drug: SO-C101; Drug: pembrolizumab
Sponsor: Sotio a.s.
Recruiting

Permalink for 'Radiochemotherapy +/- Durvalumab for Locally-advanced Anal Carcinoma. A Multicenter, Randomized, Phase II Trial of the German Anal Cancer Study Group'

Radiochemotherapy +/- Durvalumab for Locally-advanced Anal Carcinoma. A Multicenter, Randomized, Phase II Trial of the German Anal Cancer Study Group

Posted: January 18th, 2020, 3:00pm GMT

Conditions: Anal Cancer; Anal Carcinoma; Anal Cancer Stage III; Anal Cancer Stage II
Interventions: Drug: Chemotherapy; Radiation: Radiation; Drug: Durvalumab
Sponsor: Goethe University
Recruiting

Incidence of HPV Infection and HPV-Associated Disease in Screening Indian Men Who Have Sex With HIV-Positive Men

Posted: October 29th, 2019, 2:00pm GMT

Conditions: HIV Infection; Human Papillomavirus Infection; Human Papillomavirus-Related Carcinoma
Interventions: Other: Cytology Specimen Collection Procedure; Procedure: High Resolution Anoscopy with Biopsy; Other: Laboratory Biomarker Analysis; Procedure: Medical Examination; Procedure: Physical Examination; Other: Questionnaire Administration
Sponsors: AIDS Malignancy Consortium; National Cancer Institute (NCI)
Not yet recruiting

The Prevent Anal Cancer Palpation Study

Posted: September 16th, 2019, 2:00pm GMT

Condition: Anal Cancer
Interventions: Behavioral: Practice Self-/Companion Exams; Behavioral: Control Arm
Sponsors: Medical College of Wisconsin; University of Chicago; M.D. Anderson Cancer Center; The University of Texas Health Science Center, Houston; Gordon Crofoot MD PA
Recruiting

Study of SQZ-PBMC-HPV in Patients With HPV16+ Recurrent, Locally Advanced or Metastatic Solid Tumors

Posted: September 10th, 2019, 2:00pm GMT

Condition: Adult Solid Tumor
Interventions: Biological: SQZ-PBMC-HPV; Drug: Atezolizumab; Drug: Ipilimumab; Drug: Nivolumab
Sponsor: SQZ Biotechnologies
Recruiting

Phase 1b/II Trial of Pembrolizumab Plus IMRT in Stage III/IV Carcinoma of Anus

Posted: August 6th, 2019, 2:00pm GMT

Conditions: Anal Cancer Stage III A; Anal Cancer Stage III B
Intervention: Drug: Pembrolizumab
Sponsor: Cardiff University
Recruiting

The Registry of Oncology Outcomes Associated With Testing and Treatment

Posted: July 22nd, 2019, 2:00pm GMT

Conditions: Adenocarcinoma; Adenocystic Carcinoma; Anal Cancer; Appendix Cancer; Brain Tumor; Glioblastoma; Astrocytoma; Bile Duct Cancer; Cholangiocarcinoma; Bladder Cancer; Bone Cancer; Synovial Sarcoma; Chondrosarcoma; Liposarcoma; Sarcoma, Kaposi; Sarcoma,Soft Tissue; Sarcoma; Osteosarcoma; CNS Cancer; Brain Stem Neoplasms; Breast Cancer; Cervical Cancer; Colorectal Cancer; Rectal Cancer; Colon Cancer; Esophageal Cancer; Esophagus Cancer; Cancer of Colon; Pancreatic Cancer; Cancer of Pancreas; Testis Cancer; Testicular Cancer; Ureter Cancer; Renal Cell Carcinoma; Kidney Cancer; Gestational Trophoblastic Tumor; Head and Neck Neoplasms; Parotid Tumor; Larynx Cancer; Tongue Cancer; Pharynx Cancer; Salivary Gland Cancer; Acute Myeloid Leukemia; Chronic Myeloid Leukemia; Acute Lymphoblastic Leukemia; Multiple Myeloma; Non Hodgkin Lymphoma; Carcinoid Tumor; Lung Cancer; Neuroendocrine Tumors; Mesothelioma; Thyroid Cancer; Parathyroid Neoplasms; Adrenal Cancer; Small Bowel Cancer; Stomach Cancer; Liver Cancer; Hepatic Cancer; Melanoma; Skin Cancer; Unknown Primary Tumors; Uterine Cancer; Fallopian Tube Cancer; Ovarian Cancer; Prostate Cancer; Vaginal Cancer; Penile Cancer; Vulvar Cancer; Waldenstrom Macroglobulinemia; Cancer, Advanced; Thymus Cancer; Nasopharyngeal Carcinoma; Multiple Endocrine Neoplasia; Pheochromocytoma; Small Cell Carcinoma; Pulmonary Carcinoma
Interventions: Diagnostic Test: Biomarker Testing (L); Drug: Systemic Treatment (T); Other: Patient Reported Outcomes (P)
Sponsor: Taproot Health
Not yet recruiting

Adoptive Transfer of Tumor Infiltrating Lymphocytes for Advanced Solid Cancers

Posted: May 2nd, 2019, 2:00pm GMT

Conditions: Gastric Cancer; Colorectal Cancer; Pancreatic Cancer; Sarcoma; Mesothelioma; Neuroendocrine Tumors; Squamous Cell Cancer; Merkel Cell Carcinoma; Mismatch Repair Deficiency; Microsatellite Instability
Interventions: Biological: Tumor Infiltrating Lymphocytes (TIL); Drug: Fludarabine + Cyclophosphamide combination
Sponsor: Udai Kammula
Recruiting

Rectal Surgery Evaluation Trial (RESET)

Posted: July 2nd, 2018, 2:00pm GMT

Condition: Rectal Cancer
Intervention: Procedure: TME with LAR
Sponsors: Institut du Cancer de Montpellier - Val d'Aurelle; Intuitive Surgical
Recruiting

A Study of XmAb®20717 in Subjects With Selected Advanced Solid Tumors

Posted: May 7th, 2018, 2:00pm GMT

Conditions: Melanoma; Breast Carcinoma; Hepatocellular Carcinoma; Urothelial Carcinoma; Squamous Cell Carcinoma of the Head and Neck; Renal Cell Carcinoma; Colorectal Carcinoma; Non-small Cell Lung Carcinoma; Gastric or Gastroesophageal Junction Adenocarcinoma; Endometrial Carcinoma; Mesothelioma; Neuroendocrine Carcinoma; Cervical Cancer; Small Cell Lung Carcinoma; Squamous Cell Carcinoma of the Anus; Castration-Resistant Prostate Carcinoma; Nasopharyngeal Carcinoma; Cholangiocarcinoma; Basal Cell Carcinoma; Ovarian Carcinoma; Fallopian Tube Carcinoma; Thymoma; Thymic Carcinoma; Squamous Cell Carcinoma of the Penis; Vulvar Carcinoma; Solid Tumors With Published Evidence of Anti-tumor Activity With Anti-PD1/PDL1 and/or Anti-CTLA4-directed Therapy; Malignant Adnexal Neoplasms; Non-squamous Cell Salivary Gland Carcinoma
Intervention: Biological: XmAb20717
Sponsors: Xencor, Inc.; ICON plc
Recruiting

The Prevent Anal Cancer Self-Swab Study

Posted: April 5th, 2018, 2:00pm GMT

Condition: Anal Cancer
Interventions: Behavioral: Home-based human papillomavirus (HPV) DNA screening; Behavioral: Clinic-based human papillomavirus (HPV) DNA screening
Sponsors: Medical College of Wisconsin; National Cancer Institute (NCI); The University of Texas Health Science Center, Houston; M.D. Anderson Cancer Center
Recruiting

Safety Study of BMX-001 (Radio-protector) in Patients With Newly Diagnosed Anal Cancer

Posted: December 29th, 2017, 3:00pm GMT

Conditions: Anal Cancer, Squamous Cell Carcinoma; Radiation Exposure
Intervention: Drug: BMX-001
Sponsors: Chi Lin, MD, PhD; BioMimetix JV, LLC; University of Nebraska
Recruiting

Transanal Total Mesorectal Excision for Rectal Cancer on Anal Physiology + Fecal Incontinence

Posted: September 14th, 2017, 2:00pm GMT

Condition: Rectal Cancer
Interventions: Procedure: TaTME; Procedure: TME
Sponsor: Case Comprehensive Cancer Center
Recruiting

PEN-866 in Patients With Advanced Solid Malignancies

Posted: July 18th, 2017, 2:00pm GMT

Conditions: Carcinoma; Endometrial Adenocarcinoma; Neoplasms; Squamous Cell Carcinoma of the Anus; Adenocarcinoma of the Pancreas; Advanced Cancer; Solid Tumor; Solid Carcinoma; Squamous Cell Carcinoma of the Cervix; Squamous Cell Carcinoma; Squamous Cell Carcinoma of the Vulva; Squamous Cell Carcinoma of the Penis; Gastric Cancer; Gastric Adenocarcinoma; Gastroesophageal Junction Adenocarcinoma; Small-cell Lung Cancer; Small Cell Lung Carcinoma; Pancreatic Ductal Adenocarcinoma; Pancreatic Adenocarcinoma
Interventions: Drug: PEN-866 Sodium; Drug: fluorouracil; Drug: Folinic acid; Drug: Niraparib
Sponsor: Tarveda Therapeutics
Recruiting

Screening for Anal Cancer in Women With High-grade Vulvar Dysplasia or Vulvar Cancer.

Posted: February 23rd, 2017, 3:00pm GMT

Conditions: Vulvar Cancer; Cervical Cancer; Vulvar Dysplasia; Cervical Dysplasia; Anal Cancer; Anal Dysplasia; HPV-Related Anal Squamous Cell Carcinoma
Interventions: Procedure: Screening anal Pap smear - No high-resolution anoscopy; Procedure: Screening anal Pap smear - High-resolution anoscopy
Sponsor: Dr. Danielle Vicus
Recruiting

Proton Therapy in Reducing Toxicity in Anal Cancer

Posted: January 12th, 2017, 3:00pm GMT

Condition: Anus Neoplasms
Interventions: Radiation: Proton therapy; Drug: Chemotherapy
Sponsor: Jordan Kharofa
Recruiting

Pembrolizumab in Metastatic Anal Cancer

Posted: September 30th, 2016, 2:00pm GMT

Condition: Anal Cancer
Intervention: Drug: Pembrolizumab
Sponsors: Dana-Farber Cancer Institute; Merck Sharp & Dohme Corp.
Recruiting

Shared Decision Making With Anal Cancer Patients on Radiation Dose

Posted: May 27th, 2016, 2:00pm GMT

Condition: Anal Cancer
Interventions: Radiation: 2.15 gray and 1.8 gray. Max. 6 weeks.; Radiation: 2.15 gray and 1.8 gray. Max. 5 weeks.
Sponsor: Vejle Hospital
Recruiting

Permalink for 'Study of SIB-IMRT in Combination With 5-FU and Mitomycin-C Among Patients With Locally Advanced Anal Canal Cancer: Efficacy, Safety and Quality of Life'

Study of SIB-IMRT in Combination With 5-FU and Mitomycin-C Among Patients With Locally Advanced Anal Canal Cancer: Efficacy, Safety and Quality of Life

Posted: March 8th, 2016, 3:00pm GMT

Condition: Locally Advanced Anal Canal Cancer
Interventions: Drug: 5Fluorouracile and Mitomycin-C; Radiation: Simultaneously integrated boost of intensity modulated radiation therapy (SIB-IMRT) by tomotherapy
Sponsors: Centre Francois Baclesse; Accuray Incorporated
Recruiting

Surgery in Treating Patients With Early Stage Anal Canal or Perianal Cancer and HIV Infection

Posted: May 8th, 2015, 2:00pm GMT

Conditions: Anal Squamous Cell Carcinoma; HIV Infection; Stage 0 Anal Canal Cancer; Stage I Anal Canal Cancer
Intervention: Procedure: Therapeutic Conventional Surgery
Sponsors: AIDS Malignancy Consortium; National Cancer Institute (NCI); The Emmes Company, LLC; AIDS and Cancer Specimen Resource; University of Arkansas
Recruiting

$Permalink for 'Nivolumab and Ipilimumab in Treating Patients With HIV Associated Relapsed or Refractory Classical Hodgkin Lymphoma or Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery'$

Nivolumab and Ipilimumab in Treating Patients With HIV Associated Relapsed or Refractory Classical Hodgkin Lymphoma or Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery

Posted: April 6th, 2015, 2:00pm GMT

Conditions: Advanced Malignant Solid Neoplasm; Anal Carcinoma; HIV Infection; Kaposi Sarcoma; Lung Carcinoma; Metastatic Malignant Solid Neoplasm; Recurrent Classic Hodgkin Lymphoma; Refractory Classic Hodgkin Lymphoma; Unresectable Solid Neoplasm
Interventions: Biological: Ipilimumab; Biological: Nivolumab
Sponsor: National Cancer Institute (NCI)
Recruiting

Permalink for 'Dose Escalation Trial of Endoluminal High-Dose-Rate Brachytherapy With Concurrent Chemotherapy for Rectal or Anal Cancer in Patients With Recurrent Disease or Undergoing Non-Operative Management'

Dose Escalation Trial of Endoluminal High-Dose-Rate Brachytherapy With Concurrent Chemotherapy for Rectal or Anal Cancer in Patients With Recurrent Disease or Undergoing Non-Operative Management

Posted: July 24th, 2014, 2:00pm GMT

Condition: Rectal or Anal Cancer
Interventions: Radiation: endorectal brachytherapy; Drug: concurrent capecitabine or 5-FU; Behavioral: Questionnaires
Sponsor: Memorial Sloan Kettering Cancer Center
Recruiting

Permalink for 'Tissue Procurement for Gastric Cancer, Gastrointestinal Stromal Tumors (GIST), Esophageal Cancer, Pancreas Cancer, Hepatocellular Cancer, Biliary Cancer, Neuroendocrine, Peritoneal Mesothelioma, Anal Cancer and Colorectal Cancer in Patients Undergoing Su'

Tissue Procurement for Gastric Cancer, Gastrointestinal Stromal Tumors (GIST), Esophageal Cancer, Pancreas Cancer, Hepatocellular Cancer, Biliary Cancer, Neuroendocrine, Peritoneal Mesothelioma, Anal Cancer and Colorectal Cancer in Patients Undergoing Su

Posted: August 15th, 2011, 2:00pm GMT

Condition: Gastric Cancers
Intervention:
Sponsor: University of Chicago
Recruiting

Specimen Collections From Patients With HIV Infection, KSHV Infection, Viral-Related Pre-malignant Lesions and Cancer

Posted: November 23rd, 2000, 3:00pm GMT

Conditions: HIV; Kaposi's Sarcoma; Lymphomas; Multicentric Castleman's Disease; Primary Effusion Lymphoma
Intervention:
Sponsor: National Cancer Institute (NCI)
Recruiting

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Trial - Anal Cancers (47 unread)