Rare Cancer News & Clinical Trials » Trial

Reconstruction After Abdominoperineal Resection With Robot-assisted Harvest of VRAM Flap

Posted: January 19th, 2023, 3:00pm GMT

Conditions: Perineum; Wound; Postoperative Complications; Rectal Neoplasms; Rectus Abdominis Hernia; Prospective Studies; Wound Heal; Sexual Health
Intervention: Procedure: Reconstruction with robot-assisted rectus abdominis muscle flap
Sponsor: Oslo University Hospital
Recruiting

E7 TCR-T Cell Immunotherapy for Human Papillomavirus (HPV) Associated Cancers

Posted: January 16th, 2023, 3:00pm GMT

Conditions: Cervical Cancer; Throat Cancer; Oropharynx Cancer; Anal Cancer; Vulva Cancer; Vaginal Cancer; Penile Cancer; Metastatic Cancer; HPV-Related Malignancy; HPV-Related Carcinoma; HPV-Related Cervical Carcinoma; HPV-Related Squamous Cell Carcinoma; HPV-Related Adenocarcinoma; HPV Positive Oropharyngeal Squamous Cell Carcinoma; HPV-Associated Vaginal Adenocarcinoma; HPV-Related Adenosquamous Carcinoma; HPV-Related Endocervical Adenocarcinoma; HPV-Related Anal Squamous Cell Carcinoma; HPV-Related Penile Squamous Cell Carcinoma; HPV-Related Vulvar Squamous Cell Carcinoma; HPV Positive Rectal Squamous Cell Carcinoma
Intervention: Biological: E7 TCR-T cells
Sponsor: Christian Hinrichs
Not yet recruiting

GEMCAD-REVEAL STUDY - Circulating Tumor DNA as a Predictor of Relapse in Patients With Locally Advanced Rectal Cancer.

Posted: January 6th, 2023, 3:00pm GMT

Condition: Patients With Locally Advanced Rectal Cancer
Intervention: Drug: total neoadjuvant therapy
Sponsor: Grupo Espanol Multidisciplinario del Cancer Digestivo
Not yet recruiting

Effects of Different Treatment for Anorectal Function of Patients With Rectal Cancer

Posted: January 5th, 2023, 3:00pm GMT

Condition: Rectal Cancer
Intervention: Other: NCRT with surgery, or NCT with surgery, or surgery
Sponsors: Sixth Affiliated Hospital, Sun Yat-sen University; Nanfang Hospital of Southern Medical University
Not yet recruiting

A Phase III Trial of Anus-preservation in Low Rectal Adenocarcinoma Based on MMR/MSI Status

Posted: December 30th, 2022, 3:00pm GMT

Conditions: Toripalimab; Radiation
Interventions: Drug: Toripalimab; Radiation: CRT; Radiation: SCRT; Drug: XELIRI; Drug: FOLFRINOX
Sponsor: Zhejiang Cancer Hospital
Recruiting

The Application Value of da Vinci Linear Cutting Stapler SureForm in Robotic Anus Preserving Surgery for Rectal Cancer

Posted: December 28th, 2022, 3:00pm GMT

Conditions: Rectal Cancer; Robotic; Anastomotic Leak; Laparoscopic
Intervention: Device: Surform
Sponsor: Nanchang University
Not yet recruiting

Collecting Blood and Tissue Sample Donations for Research for HIV/AIDS-Related Cancers

Posted: December 23rd, 2022, 3:00pm GMT

Conditions: Anal Carcinoma; Hematopoietic and Lymphoid Cell Neoplasm; HIV Infection; Kaposi Sarcoma; Lymphoma; Malignant Solid Neoplasm; Multicentric Castleman Disease; Plasmablastic Lymphoma; Recurrent Kaposi Sarcoma; Recurrent Lymphoma; Recurrent Plasmablastic Lymphoma; Transplant-Related Kaposi Sarcoma
Intervention: Procedure: Biospecimen Collection
Sponsors: AIDS Malignancy Consortium; National Cancer Institute (NCI)
Not yet recruiting

Tiraglolumab Atezolizumab and Chemoradiotherapy in Localized Anal Carcinoma (TIRANUS)

Posted: December 22nd, 2022, 3:00pm GMT

Condition: Squamous Cell Carcinoma of the Anal Canal
Intervention: Drug: Atezolizumab plus Tiraglolumab
Sponsors: Grupo Espanol Multidisciplinario del Cancer Digestivo; Hoffmann-La Roche
Not yet recruiting

The Anatomical Localization of the Inferior Mesenteric Artery in Relation to the Left Colonic Artery

Posted: December 15th, 2022, 3:00pm GMT

Condition: Rectal Cancer
Intervention: Behavioral: measurement group
Sponsor: Tang-Du Hospital
Recruiting

E7 T-cell Receptor (TCR) -T Cell Induction Therapy for Locoregionally Advanced HPV-associated Cancers

Posted: December 7th, 2022, 3:00pm GMT

Conditions: HPV-Associated Cervical Carcinoma; HPV-Related Carcinoma; HPV-Related Malignancy; HPV Positive Oropharyngeal Squamous Cell Carcinoma; HPV-Related Adenocarcinoma; HPV-Related Adenosquamous Carcinoma; HPV-Related Squamous Cell Carcinoma; HPV-Related Anal Squamous Cell Carcinoma; HPV-Related Penile Squamous Cell Carcinoma; HPV-Related Vulvar Squamous Cell Carcinoma; HPV-Related Endocervical Adenocarcinoma; Cervical Cancer; Oropharynx Cancer; Anal Cancer; Vulvar Cancer; Penile Cancer; Vaginal Cancer
Intervention: Drug: Conditioning, E7 TCR-T cells, and aldesleukin
Sponsors: Christian Hinrichs; National Cancer Institute (NCI)
Not yet recruiting

Permalink for 'A Study to Assess the Reduction of Human Papillomavirus (HPV) Viral Infectivity and Transmission in HPV-Positive Women After Vaccination With 9vHPV (RIFT-HPV)'

A Study to Assess the Reduction of Human Papillomavirus (HPV) Viral Infectivity and Transmission in HPV-Positive Women After Vaccination With 9vHPV (RIFT-HPV)

Posted: April 19th, 2022, 2:00pm GMT

Conditions: Cervical Intraepithelial Neoplasia Grade I/ II/ III (CIN I/II/III); Human Papillomavirus (HPV) Infections; High-risk HPV; HPV-16/ 18
Intervention: Biological: Nonavalent HPV vaccine (9vHPV/Gardasil-9™).
Sponsors: Miquel Angel Pavon Ribas; Hospital del Mar; Catalan Institute of Health
Recruiting

Permalink for 'Screening Algorithms for Cervical and Anal High-Grade Squamous Intraepithelial Lesions in People With HIV in Mexico and Puerto Rico'

Screening Algorithms for Cervical and Anal High-Grade Squamous Intraepithelial Lesions in People With HIV in Mexico and Puerto Rico

Posted: October 12th, 2021, 2:00pm GMT

Conditions: AIDS-Related Anal Carcinoma; AIDS-Related Cervical Carcinoma; High Grade Anal Intraepithelial Neoplasia; High Grade Cervical Intraepithelial Neoplasia; HIV Infection
Interventions: Procedure: Biopsy; Procedure: Biospecimen Collection - Anal; Procedure: Biospecimen Collection - Cervical; Procedure: Colposcopy; Procedure: High Resolution Anoscopy; Procedure: Imaging Technique
Sponsors: University of California, San Francisco; National Cancer Institute (NCI); US-Latin American-Caribbean HIV/HPV-Cancer Prevention Clinical Trials Network (ULACNet)
Recruiting

Therapy Adapted for High Risk and Low Risk HIV-Associated Anal Cancer

Posted: June 18th, 2021, 2:00pm GMT

Conditions: AIDS-Related Anal Carcinoma; Anal Basaloid Carcinoma; Anal Canal Cloacogenic Carcinoma; Anal Margin Squamous Cell Carcinoma; Anal Squamous Cell Carcinoma; HIV Infection; Rectal Squamous Cell Carcinoma; Stage I Anal Cancer AJCC v8; Stage II Anal Cancer AJCC v8; Stage II Rectal Cancer AJCC v8; Stage IIA Anal Cancer AJCC v8; Stage IIA Rectal Cancer AJCC v8; Stage IIB Anal Cancer AJCC v8; Stage IIB Rectal Cancer AJCC v8; Stage IIC Rectal Cancer AJCC v8; Stage III Anal Cancer AJCC v8; Stage III Rectal Cancer AJCC v8; Stage IIIA Anal Cancer AJCC v8; Stage IIIA Rectal Cancer AJCC v8; Stage IIIB Anal Cancer AJCC v8; Stage IIIB Rectal Cancer AJCC v8; Stage IIIC Anal Cancer AJCC v8; Stage IIIC Rectal Cancer AJCC v8
Interventions: Drug: Capecitabine; Drug: Fluorouracil; Radiation: Intensity-Modulated Radiation Therapy; Drug: Mitomycin; Biological: Nivolumab
Sponsor: National Cancer Institute (NCI)
Recruiting

Pomalidomide and Nivolumab in People With Virus-Associated Malignancies With or Without HIV

Posted: May 26th, 2021, 2:00pm GMT

Conditions: Viral Associated Malignancies; Kaposi Sarcoma; EBV/KSHV-associated Lymphomas
Interventions: Drug: Pomalidomide; Drug: Nivolumab
Sponsor: National Cancer Institute (NCI)
Recruiting

Permalink for 'Oral Cryotherapy Plus Acupressure and Acupuncture Versus Oral Cryotherapy for Decreasing Chemotherapy-Induced Peripheral Neuropathy From Oxaliplatin-Based Chemotherapy in Patients With Gastrointestinal Cancer'

Oral Cryotherapy Plus Acupressure and Acupuncture Versus Oral Cryotherapy for Decreasing Chemotherapy-Induced Peripheral Neuropathy From Oxaliplatin-Based Chemotherapy in Patients With Gastrointestinal Cancer

Posted: August 10th, 2020, 2:00pm GMT

Conditions: Appendix Carcinoma; Colon Carcinoma; Esophageal Carcinoma; Gastric Carcinoma; Liver and Intrahepatic Bile Duct Carcinoma; Malignant Digestive System Neoplasm; Pancreatic Carcinoma; Rectal Carcinoma; Small Intestinal Carcinoma; Anal Carcinoma; Digestive System Carcinoma; Digestive System Neuroendocrine Tumor; Pancreatic Neuroendocrine Tumor
Interventions: Procedure: Acupuncture Therapy; Procedure: Acupressure Therapy; Procedure: Oral Cryotherapy; Other: Questionnaire Administration; Other: Quality-of-Life Assessment
Sponsors: University of Washington; National Cancer Institute (NCI); The Safeway Foundation
Recruiting

Prebiotics and Probiotics During Definitive Treatment With Chemotherapy-radiotherapy SCC of the Anal Canal (BISQUIT)

Posted: March 12th, 2019, 2:00pm GMT

Condition: Anal Cancer Squamous Cell
Intervention: Dietary Supplement: prebiotics in combination with probiotics
Sponsor: AC Camargo Cancer Center
Recruiting

Safety Study of BMX-001 (Radio-protector) in Patients With Newly Diagnosed Anal Cancer

Posted: December 29th, 2017, 3:00pm GMT

Conditions: Anal Cancer, Squamous Cell Carcinoma; Radiation Exposure
Intervention: Drug: BMX-001
Sponsors: Chi Lin, MD, PhD; BioMimetix JV, LLC; University of Nebraska
Recruiting

Study of Pembrolizumab (MK-3475) in Participants With Advanced Solid Tumors (MK-3475-158/KEYNOTE-158)

Posted: December 11th, 2015, 3:00pm GMT

Conditions: Advanced Cancer; Anal Carcinoma; Anal Cancer; Biliary Cancer; Cholangiocarcinoma; Bile Duct Cancer; Neuroendocrine Tumor; Carcinoid Tumor; Endometrial Carcinoma; Endometrial Cancer; Cervical Carcinoma; Cervical Cancer; Vulvar Carcinoma; Vulvar Cancer; Small Cell Lung Carcinoma; Small Cell Lung Cancer (SCLC); Mesothelioma; Thyroid Carcinoma; Thyroid Cancer; Salivary Gland Carcinoma; Salivary Gland Cancer; Salivary Cancer; Parotid Gland Cancer; Advanced Solid Tumors; Colorectal Carcinoma
Intervention: Biological: pembrolizumab
Sponsor: Merck Sharp & Dohme LLC
Recruiting

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Trial - Anal Cancers (18 unread)