Rare Cancer News » Trial - Neuroendocrine Cancers

Trial - Neuroendocrine Cancers (50 unread)

Pilot Trial of "Chemo-Switch" Regimen to Treat Advanced Melanoma

Posted: May 4th, 2008, 10:00am EDT

Condition: Melanoma
Interventions: Drug: Concurrent decrescendo biochemotherapy regimen; Drug: Low-dose Temozolomide plus Sorafenib
Sponsors: Duke University; Bayer
Active, not recruiting - verified May 2008
Answering Questions About Vitamin D Supplementation and Sun Exposure in Patients Who Have Undergone Surgery for Stage IB, Stage II, or Stage IIIA Melanoma

Posted: May 3rd, 2008, 10:00am EDT

Condition: Melanoma (Skin)
Interventions: Procedure: gene expression analysis; Procedure: laboratory biomarker analysis; Procedure: mutation analysis; Procedure: polymorphism analysis; Procedure: questionnaire administration
Sponsor: Leeds Cancer Centre at St. James's University Hospital
Recruiting - verified May 2008
A Pilot Study to Investigate MEN1 and SDHD Gene Mutation in Carcinoid

Posted: May 2nd, 2008, 10:00am EDT

Condition: Carcinoid Neuroendocrine Cancer
Intervention:
Sponsor: Rutgers University
Recruiting - verified May 2008
Cyclophosphamide and Fludarabine Followed By Laboratory-Treated Lymphocytes and High-Dose Aldesleukin in Treating Patients With Metastatic Cancer

Posted: May 1st, 2008, 10:00am EDT

Conditions: Kidney Cancer; Melanoma (Skin); Unspecified Adult Solid Tumor, Protocol Specific
Interventions: Drug: aldesleukin; Drug: cyclophosphamide; Drug: fludarabine phosphate; Drug: therapeutic autologous lymphocytes; Procedure: fluorescence activated cell sorting; Procedure: gene therapy; Procedure: genetically engineered lymphocyte therapy; Procedure: immunologic technique; Procedure: immunopotentiation therapy; Procedure: in vitro-treated peripheral blood lymphocyte therapy; Procedure: interleukin therapy; Procedure: parenteral chemotherapy; Procedure: polymerase chain reaction; Procedure: reverse transcriptase-polymerase chain reaction
Sponsor: National Cancer Institute (NCI)
Recruiting - verified April 2008
Pancreatic Stent to Prevent Leak After Distal Pancreatectomy

Posted: May 1st, 2008, 10:00am EDT

Conditions: Pancreatic Surgery; Pancreatic Duct Stenting; Pancreatic Cancer; Distal Pancreatectomy; Pancreatic Diseases; Pancreatic Cyst; Pancreatic Ducts
Intervention: Procedure: Pancreatic duct stenting
Sponsors: Massachusetts General Hospital; American Society for Gastrointestinal Endoscopy
Enrolling by invitation - verified May 2008
Phase 3 Breast and Melanoma Trial Using Lymphoseek

Posted: April 30th, 2008, 10:00am EDT

Conditions: Breast Cancer; Melanoma
Intervention: Drug: Lymphoseek
Sponsor: Neoprobe Corporation
Recruiting - verified May 2008
Trial of Melaxin Cancer Vaccine Plus Bacillus Calmette-Guerin (BCG) to Treat Malignant Melanoma

Posted: April 30th, 2008, 10:00am EDT

Condition: Melanoma
Intervention: Biological: Melaxin (autologous dendritoma vaccine) and BCG
Sponsors: Greenville Hospital System University Medical Center; Oncolix
Recruiting - verified April 2008
Adrenal Tumors - Pathogenesis and Therapy

Posted: April 28th, 2008, 10:00am EDT

Conditions: Adrenal Tumors; Adrenocortical Carcinoma; Cushing Syndrome; Conn Syndrome; Pheochromocytoma
Intervention:
Sponsors: University of Wuerzburg; Deutsche Krebshilfe e.V., Bonn (Germany); Bundesministerium für Bildung und Forschung (BMBF)
Recruiting - verified April 2008
AZD0530 in Treating Patients With Stage III or Stage IV Melanoma That Cannot Be Removed By Surgery

Posted: April 26th, 2008, 10:00am EDT

Condition: Melanoma (Skin)
Interventions: Drug: AZD0530; Procedure: immunoenzyme technique; Procedure: laboratory biomarker analysis; Procedure: protein tyrosine kinase inhibitor therapy; Procedure: western blotting
Sponsors: University of Chicago; National Cancer Institute (NCI)
Not yet recruiting - verified April 2008
Paclitaxel and Bortezomib in Treating Patients With Metastatic or Unresectable Malignant Solid Tumors

Posted: April 25th, 2008, 10:00am EDT

Conditions: Breast Cancer; Colorectal Cancer; Head and Neck Cancer; Lung Cancer; Melanoma (Skin); Ovarian Cancer; Pancreatic Cancer; Prostate Cancer; Unspecified Adult Solid Tumor, Protocol Specific
Interventions: Drug: bortezomib; Drug: paclitaxel; Procedure: enzyme inhibitor therapy; Procedure: high performance liquid chromatography; Procedure: immunohistochemistry staining method; Procedure: laboratory biomarker analysis; Procedure: parenteral chemotherapy; Procedure: pharmacological study; Procedure: protein expression analysis; Procedure: western blotting
Sponsors: Cancer Institute of New Jersey; National Cancer Institute (NCI)
Not yet recruiting - verified April 2008
Riluzole in Treating Patients With Stage III or Stage IV Melanoma That Can Be Removed By Surgery

Posted: April 25th, 2008, 10:00am EDT

Condition: Melanoma (Skin)
Interventions: Drug: riluzole; Procedure: immunohistochemistry staining method; Procedure: laboratory biomarker analysis; Procedure: neoadjuvant therapy; Procedure: pharmacological study; Procedure: protein expression analysis; Procedure: receptor antagonist therapy; Procedure: reverse transcriptase-polymerase chain reaction; Procedure: therapeutic conventional surgery; Procedure: western blotting
Sponsors: Cancer Institute of New Jersey; National Cancer Institute (NCI)
Not yet recruiting - verified April 2008
Intratumoral Injection Of Alpha-Gal Glycosphingolipids

Posted: April 25th, 2008, 10:00am EDT

Condition: Metastatic Melanoma
Intervention: Biological: Alpha-Gal Glycosphingolipids
Sponsor: University of Massachusetts
Recruiting - verified April 2008
Study of Temzolomide and Gleevec in Advanced Melanoma

Posted: April 24th, 2008, 10:00am EDT

Conditions: Melanoma; Advanced Melanoma
Intervention: Drug: Gleevec + Temozolomide
Sponsors: University of Pennsylvania; Novartis
Recruiting - verified April 2008
Laboratory-Treated Autologous Peripheral Blood Lymphocytes, Aldesleukin, Cyclophosphamide, and Fludarabine in Treating Patients With Metastatic Melanoma

Posted: April 23rd, 2008, 10:00am EDT

Condition: Melanoma (Skin)
Interventions: Drug: aldesleukin; Drug: cyclophosphamide; Drug: filgrastim; Drug: fludarabine phosphate; Drug: therapeutic autologous lymphocytes; Procedure: flow cytometry; Procedure: hematologic toxicity attenuation; Procedure: immunoenzyme technique; Procedure: in vitro-treated peripheral blood lymphocyte therapy; Procedure: interleukin therapy; Procedure: laboratory biomarker analysis; Procedure: parenteral chemotherapy; Procedure: polymerase chain reaction
Sponsor: National Cancer Institute (NCI)
Recruiting - verified April 2008
Proteasome Inhibitor NPI-0052 and Vorinostat in Patients With Non-Small Cell Lung Cancer, Pancreatic Cancer or Melanoma

Posted: April 22nd, 2008, 10:00am EDT

Conditions: Non-Small Cell Lung Cancer; Pancreatic Cancer; Melanoma
Intervention: Drug: NPI-0052 + vorinostat
Sponsor: Nereus Pharmaceuticals, Inc.
Recruiting - verified April 2008
Extension Study of the Safety and Efficacy of Atiprimod Treatment in Neuroendocrine Carcinoma

Posted: April 18th, 2008, 10:00am EDT

Condition: Neuroendocrine Carcinoma
Intervention: Drug: Atiprimod
Sponsor: Callisto Pharmaceuticals
Recruiting - verified April 2008
Buthionine Sulfoximine and an Isolated Limb Infusion of Melphalan in Treating Patients With Persistent or Recurrent Stage III Malignant Melanoma

Posted: April 17th, 2008, 10:00am EDT

Condition: Melanoma (Skin)
Interventions: Drug: buthionine sulfoximine; Drug: melphalan; Procedure: biopsy; Procedure: drug resistance inhibition treatment; Procedure: enzyme inhibitor therapy; Procedure: gene expression profiling; Procedure: high performance liquid chromatography; Procedure: isolated limb infusion; Procedure: laboratory biomarker analysis; Procedure: pharmacological study
Sponsors: Duke University; National Cancer Institute (NCI)
Recruiting - verified April 2008
An Investigation of Small Intestinal Carcinoid Carcinoma in Families

Posted: April 17th, 2008, 10:00am EDT

Condition: Carcinoid Carcinoma
Intervention:
Sponsor: Rutgers University
Recruiting - verified April 2008
Halt Growth of Liver Tumors From Uveal Melanoma With Closure of Liver Artery Following Injection of GM-CSF

Posted: April 16th, 2008, 10:00am EDT

Conditions: Uveal Melanoma; Liver Metastases
Interventions: Drug: GM-CSF; Procedure: Embolization; Procedure: Embolization
Sponsors: Thomas Jefferson University; National Institutes of Health (NIH)
Recruiting - verified April 2008
Monoclonal Antibody Therapy in Treating Patients With Stage IV Melanoma

Posted: April 12th, 2008, 10:00am EDT

Condition: Melanoma (Skin)
Interventions: Drug: B7-DC cross-linking antibody rHIgM12B7; Procedure: flow cytometry; Procedure: immunologic technique; Procedure: laboratory biomarker analysis; Procedure: monoclonal antibody therapy
Sponsors: Mayo Clinic; National Cancer Institute (NCI)
Recruiting - verified May 2008
Randomized Study Of Cisplatin-Etoposide Versus An Etoposide Regimen Without Cisplatin In Extensive Small-Cell Lung Cancer

Posted: April 11th, 2008, 10:00am EDT

Condition: Small Cell Lung Carcinoma, Extensive Disease
Interventions: Drug: Cisplatin + etoposide; Drug: Epirubicin + ifosfamide + etoposide
Sponsor: European Lung Cancer Working Party
Recruiting - verified April 2008
Phase3 Study of Amrubicin With Cisplatin Versus Etoposide-Cisplatin for Extensive Disease Small Cell Lung Cancer

Posted: April 10th, 2008, 10:00am EDT

Condition: Lung Cancer
Interventions: Drug: Amrubicin Hydrochloride; Drug: Etoposide-Cisplatin combined chemotherapy
Sponsor: Sumiyaku China Co., Ltd.
Recruiting - verified April 2008
Everolimus and Vatalanib in Treating Patients With Advanced Solid Tumors

Posted: April 9th, 2008, 10:00am EDT

Conditions: Gastrointestinal Carcinoid Tumor; Head and Neck Cancer; Islet Cell Tumor; Kidney Cancer; Lung Cancer; Melanoma (Skin); Neuroendocrine Carcinoma of the Skin; Pheochromocytoma; Unspecified Adult Solid Tumor, Protocol Specific
Interventions: Drug: everolimus; Drug: vatalanib; Procedure: antiangiogenesis therapy; Procedure: enzyme inhibitor therapy; Procedure: protein tyrosine kinase inhibitor therapy
Sponsors: Mayo Clinic; National Cancer Institute (NCI)
Recruiting - verified April 2008
Clinical and Pathologic Studies in Neuroendocrine Tumors

Posted: April 9th, 2008, 10:00am EDT

Condition: Carcinoid Tumor
Interventions: Procedure: blood sample draw; Procedure: urine sample
Sponsor: Stanford University
Not yet recruiting - verified May 2008
CY503 for the Treatment of Malignant Melanoma Stage IV After Failure of Prior Therapy

Posted: April 9th, 2008, 10:00am EDT

Condition: Melanoma
Intervention: Drug: CY-503
Sponsor: Cytavis Biopharma GmbH
Recruiting - verified December 2007
Irinotecan, Fluorouracil, and Leucovorin in Treating Patients With Advanced Gastrointestinal Cancer

Posted: April 4th, 2008, 10:00am EDT

Conditions: Anal Cancer; Carcinoma of the Appendix; Colorectal Cancer; Esophageal Cancer; Extrahepatic Bile Duct Cancer; Gallbladder Cancer; Gastric Cancer; Gastrointestinal Carcinoid Tumor; Gastrointestinal Stromal Tumor; Liver Cancer; Pancreatic Cancer; Small Intestine Cancer
Interventions: Drug: fluorouracil; Drug: irinotecan hydrochloride; Drug: leucovorin calcium; Procedure: parenteral chemotherapy; Procedure: pharmacogenomic studies; Procedure: pharmacological study
Sponsors: Mayo Clinic; National Cancer Institute (NCI)
Not yet recruiting - verified April 2008
Viral Therapy in Treating Patients With Metastatic Melanoma

Posted: April 1st, 2008, 10:00am EDT

Condition: Melanoma (Skin)
Interventions: Drug: wild-type reovirus; Procedure: electron microscopy; Procedure: immunoenzyme technique; Procedure: immunohistochemistry staining method; Procedure: laboratory biomarker analysis; Procedure: oncolytic virus therapy
Sponsors: Mayo Clinic; National Cancer Institute (NCI)
Recruiting - verified April 2008
Safety and Immunogenicity of a Melan-A VLP Vaccine With and Without Adjuvant in Advanced Stage Melanoma Patients

Posted: April 1st, 2008, 10:00am EDT

Condition: Malignant Melanoma
Interventions: Biological: CYT004-MelQbG10 + Montanide; Biological: CYT004-MelQbG10 + Montanide + Imiquimod; Biological: CYT004-MelQbG10 + Imiquimod; Biological: CYT004-MelQbG10 intra nodal injection
Sponsor: Cytos Biotechnology AG
Recruiting - verified April 2008
Natural History of Familial Carcinoid Tumor

Posted: March 26th, 2008, 10:00am EDT

Conditions: Carcinoid; Familial; PET; Gastrointestinal; Serotonin
Intervention:
Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Recruiting - verified March 2008
Clinical Evaluation of 18F-DOPA Positron Emission Tomography in Medullary Thyroid Cancer

Posted: March 26th, 2008, 10:00am EDT

Conditions: Thyroid Neoplasm; Thyroid Carcinoma; Medullary Carcinoma
Intervention: Other: 18F-L-DOPA PET
Sponsor: Assistance Publique - Hôpitaux de Paris
Recruiting - verified October 2007
Assessment of Cardiovascular Risk Markers in Growth Hormone Deficient Patients With Nonsecreting Pituitary Adenomas

Posted: March 25th, 2008, 10:00am EDT

Conditions: Growth Hormone Deficiency; Pituitary Tumor
Intervention:
Sponsors: Columbia University; EMD Serono; Genentech
Recruiting - verified March 2008
Phase II Trial of Consolidative Thoracic Radiotherapy for Extensive Stage Small Cell Lung Cancer

Posted: March 24th, 2008, 10:00am EDT

Condition: Extensive Stage Small Cel Lung Cancer
Intervention: Radiation: thoracic radiotherapy
Sponsor: Alberta Cancer Board
Recruiting - verified March 2008
Interferon Alfa-2b in Treating Patients Who Have Undergone Surgery for High-Risk or Metastatic Melanoma

Posted: March 11th, 2008, 10:00am EDT

Condition: Melanoma (Skin)
Interventions: Drug: recombinant interferon alfa-2b; Procedure: adjuvant therapy; Procedure: flow cytometry; Procedure: gene expression analysis; Procedure: gene expression profiling; Procedure: immunohistochemistry staining method; Procedure: immunopotentiation therapy; Procedure: interferon therapy; Procedure: laboratory biomarker analysis; Procedure: reverse transcriptase-polymerase chain reaction
Sponsors: Arthur G. James Cancer Hospital & Richard J. Solove Research Institute; National Cancer Institute (NCI)
Not yet recruiting - verified April 2008
N-AcetylCysteine vs. Placebo to Prevent Neurotoxicity Induced by Platinum Containing Chemotherapy

Posted: March 11th, 2008, 10:00am EDT

Conditions: Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell Lung; Mesothelioma
Interventions: Drug: N-Acetylcysteine; Drug: Placebo
Sponsor: Rijnstate Hospital
Not yet recruiting - verified March 2008
Three Different Radiation Therapy Regimens in Treating Patients With Limited-Stage Small Cell Lung Cancer Receiving Cisplatin and Etoposide

Posted: March 8th, 2008, 10:00am EST

Condition: Lung Cancer
Interventions: Drug: cisplatin; Drug: etoposide; Procedure: 3-dimensional conformal radiation therapy; Procedure: intensity-modulated radiation therapy; Procedure: systemic chemotherapy
Sponsors: Cancer and Leukemia Group B; National Cancer Institute (NCI); Radiation Therapy Oncology Group
Recruiting - verified May 2008
Coxsackie Virus A21 Administered IV for Solid Tumour Cancers

Posted: March 7th, 2008, 10:00am EST

Conditions: Melanoma; Breast Cancer; Prostate Cancer
Intervention: Drug: CVA21
Sponsor: Viralytics
Recruiting - verified April 2008
Efficacy Study of Ipilimumab Versus Placebo to Prevent Recurrence After Complete Resection of High Risk Stage III Melanoma

Posted: March 7th, 2008, 10:00am EST

Condition: High Risk Stage III Melanoma
Interventions: Drug: ipilimumab; Drug: Placebo
Sponsor: Bristol-Myers Squibb
Not yet recruiting - verified April 2008
Clinical Trial of Sutent to Treat Metastatic Melanoma

Posted: March 3rd, 2008, 10:00am EST

Condition: Metastatic Melanoma
Intervention: Drug: Sutent (sunitinib)
Sponsors: California Pacific Medical Center Research Institute; Pfizer; University of California, San Francisco
Recruiting - verified February 2008
Phase II Melanoma Epirubicin Sulindac Trial

Posted: February 29th, 2008, 10:00am EST

Condition: Malignant Melanoma
Intervention: Drug: Epirubicin and Sulindac
Sponsor: All Ireland Cooperative Oncology Research Group
Recruiting - verified February 2008
Bevacizumab and Temozolomide or Bevacizumab and Paclitaxel Albumin-Stabilized Nanoparticle Formulation and Carboplatin in Treating Patients With Stage IV Malignant Melanoma That Cannot Be Removed by Surgery

Posted: February 28th, 2008, 10:00am EST

Condition: Melanoma (Skin)
Interventions: Drug: bevacizumab; Drug: carboplatin; Drug: paclitaxel albumin-stabilized nanoparticle formulation; Drug: temozolomide; Procedure: antiangiogenesis therapy; Procedure: monoclonal antibody therapy; Procedure: systemic chemotherapy
Sponsors: North Central Cancer Treatment Group; National Cancer Institute (NCI)
Not yet recruiting - verified May 2008
In Vitro Expanded Autologous Invariant Natural Killer Cells in Cancer

Posted: February 28th, 2008, 10:00am EST

Condition: Malignant Melanoma
Interventions: Biological: in vitro expanded autologous invariant natural killer T cells; Drug: GM-CSF
Sponsors: Beth Israel Deaconess Medical Center; Dana-Farber Cancer Institute
Recruiting - verified February 2008
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BB-10901 in Treating Patients With Relapsed or Refractory Solid Tumors

Posted: February 26th, 2008, 10:00am EST

Conditions: Cervical Cancer; Gastrointestinal Carcinoid Tumor; Lung Cancer; Sarcoma; Unspecified Adult Solid Tumor, Protocol Specific
Interventions: Drug: BB-10901; Procedure: antibody-drug conjugate therapy; Procedure: monoclonal antibody therapy
Sponsor: ImmunoGen, Inc.
Suspended - verified October 2007
The Use of Dendritic Cell/Tumor Hybridomas as a Novel Tumor Vaccine in Patients With Advance Melanoma

Posted: February 21st, 2008, 10:00am EST

Condition: Metastatic Melanoma
Intervention: Biological: DC/tumor fusion vaccine
Sponsors: Beth Israel Deaconess Medical Center; Genzyme
Active, not recruiting - verified February 2008
A Study Evaluating the Safety and Antitumor Activity of IP-504, in Patients With Metastatic Melanoma

Posted: February 21st, 2008, 10:00am EST

Condition: Metastatic Melanoma
Intervention: Drug: IPI-504
Sponsor: MedImmune LLC
Recruiting - verified March 2008
Study of AS1409 in Patients With Either Metastatic Renal Cell Carcinoma or Metastatic Malignant Melanoma

Posted: February 20th, 2008, 10:00am EST

Conditions: Metastatic Renal Cell Carcinoma; Metastatic Malignant Melanoma
Intervention: Drug: AS1409
Sponsor: Antisoma Research
Recruiting - verified February 2008
Bevacizumab and Paclitaxel for Neuroendocrine Tumors of the Cervix

Posted: February 20th, 2008, 10:00am EST

Conditions: Cervical Cancer; Uterine Cancer
Interventions: Drug: Bevacizumab; Drug: Paclitaxel
Sponsors: M.D. Anderson Cancer Center; Genentech
Recruiting - verified February 2008
The Safety and Efficacy of CPTK787/ZK222584 in Patients With Metastatic Neuroendocrine Tumors

Posted: February 20th, 2008, 10:00am EST

Condition: Neuroendocrine Tumors
Intervention: Drug: PTK787/ZK222584
Sponsors: University of Iowa; Novartis
Recruiting - verified February 2008
Vaccine Therapy and Chemotherapy With or Without Tretinoin in Treating Patients With Extensive-Stage Small Cell Lung Cancer

Posted: February 19th, 2008, 10:00am EST

Condition: Lung Cancer
Interventions: Drug: autologous dendritic cell-adenovirus p53 vaccine; Drug: carboplatin; Drug: etoposide; Drug: paclitaxel; Drug: tretinoin; Procedure: adjuvant therapy; Procedure: chemotherapy; Procedure: differentiation therapy; Procedure: laboratory biomarker analysis; Procedure: recombinant viral vaccine therapy
Sponsors: H. Lee Moffitt Cancer Center and Research Institute; National Cancer Institute (NCI)
Recruiting - verified March 2008
Study of Ipilimumab to Treat Melanoma in Patients With Brain Metastases

Posted: February 19th, 2008, 10:00am EST

Condition: Melanoma
Intervention: Drug: Ipilimumab
Sponsors: Bristol-Myers Squibb; Medarex
Recruiting - verified April 2008
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Safety Study of Recombinant Vaccinia Virus to Treat Refractory Solid Tumors

Posted: February 19th, 2008, 10:00am EST

Conditions: Melanoma; Lung Cancer; Renal Cell Carcinoma; Squamous Cell Carcinoma of the Head and Neck
Intervention: Drug: Recombinant Vaccinia GM-CSF; RAC VAC GM-CSF (JX-594)
Sponsor: Jennerex Biotherapeutics
Not yet recruiting - verified February 2008

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Rare Cancer News » Trial - Neuroendocrine Cancers

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Trial - Neuroendocrine Cancers (50 unread)

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