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Trial - CNS Tumor (100 unread)

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Risk-Adapted Chemotherapy in Younger Patients With Newly Diagnosed Standard-Risk Acute Lymphoblastic Leukemia

Posted: August 27th, 2010, 9:00am CDT

Condition: Leukemia
Interventions: Drug: cyclophosphamide; Drug: cytarabine; Drug: dexamethasone; Drug: doxorubicin hydrochloride; Drug: leucovorin calcium; Drug: mercaptopurine; Drug: methotrexate; Drug: pegaspargase; Drug: thioguanine; Drug: vincristine sulfate
Sponsors: Children's Oncology Group; National Cancer Institute (NCI)
Not yet recruiting - verified August 2010
Ofatumumab and High-dose Methylprednisolone in Patients With Chronic Lymphocytic Leukemia (CLL)

Posted: August 26th, 2010, 9:00am CDT

Condition: CLL
Intervention: Drug: Ofatumumab/HDMP
Sponsors: Chronic Lymphocytic Leukemia Research Consortium; GlaxoSmithKline
Recruiting - verified August 2010
Vorinostat and Radiation Therapy Followed By Maintenance Therapy With Vorinostat in Treating Younger Patients With Newly Diagnosed Pontine Glioma

Posted: August 25th, 2010, 9:00am CDT

Condition: Brain and Central Nervous System Tumors
Interventions: Drug: vorinostat; Radiation: 3-dimensional conformal radiation therapy; Radiation: intensity-modulated radiation therapy
Sponsors: Children's Oncology Group; National Cancer Institute (NCI)
Not yet recruiting - verified August 2010
R04929097 and Bevacizumab in Treating Patients With Progressive or Recurrent Malignant Glioma

Posted: August 25th, 2010, 9:00am CDT

Condition: Brain and Central Nervous System Tumors
Interventions: Biological: bevacizumab; Drug: gamma-secretase inhibitor RO4929097
Sponsor: National Cancer Institute (NCI)
Not yet recruiting - verified August 2010
A Phase II Trial of Poly-ICLC in the Management of Recurrent Pediatric Low Grade Gliomas

Posted: August 23rd, 2010, 9:00am CDT

Conditions: Juvenile Pilcytic Astrocytoma (JPA); Pleomorphic JPA; Diffuse Astrocytoma (Fibrillary, Gemistocytic, Giant Cell, or Pleomorphic Xanthoastrocytoma); Low Grade Oligoastrocytoma; Low Grade Oligodendroglioma; Low Grade Glioma NOS
Intervention: Drug: Poly ICLC
Sponsors: Emory University; University of California, San Diego
Recruiting - verified August 2010
Low-dose (12 Gy) TSEBT+Vorinostat Versus Low-dose TSEBT Monotherapy in Mycosis Fungoides

Posted: August 20th, 2010, 9:00am CDT

Conditions: Lymphomas: Non-Hodgkin Cutaneous Lymphoma; Lymphomas: Non-Hodgkin
Interventions: Procedure: 12Gy total skin electron beam therapy; Drug: Vorinostat
Sponsor: Stanford University
Not yet recruiting - verified August 2010
Combined Immunochemotherapy in Patients With T-Prolymphocytic Leukemia (T-PLL)

Posted: August 20th, 2010, 9:00am CDT

Condition: T-cell-prolymphocytic Leukemia
Intervention: Drug: Fludarabine, Mitoxantrone, Cyclophosphamide and Alemtuzumab
Sponsors: German CLL Study Group; Genzyme; University of Cologne
Recruiting - verified August 2010
EZN-3042 Administered With Re-induction Chemotherapy in Children With Relapsed Acute Lymphoblastic Leukemia (ALL)

Posted: August 19th, 2010, 9:00am CDT

Conditions: Lymphoblastic Leukemia, Acute; Lymphoblastic Leukemia, Acute, Childhood; Leukemia, Lymphoblastic, Acute, T Cell; Leukemia, Lymphoblastic, Acute
Interventions: Drug: EZN-3042; Drug: Cytarabine; Drug: Doxorubicin; Drug: Prednisone; Drug: Vincristine; Drug: Pegaspargase; Drug: Methotrexate
Sponsors: Therapeutic Advances in Childhood Leukemia Consortium; Enzon Pharmaceuticals, Inc.
Recruiting - verified August 2010
The Clinical Evaluation Implantable Pump System For Safety And Delivery Accuracy In Patients Requiring Intrathecal Administration Of Morphine Sulfate For Chronic Pain

Posted: August 18th, 2010, 9:00am CDT

Conditions: Cancers; Chronic Pain
Intervention: Device: Implantation of Morphine Sulfate delivring programmable pump
Sponsor: The Alfred E. Mann Foundation for Scientific Research
Not yet recruiting - verified August 2010
Pilot Trial of Sirolimus/MEC in High Risk Acute Myelogenous Leukemia (AML)

Posted: August 17th, 2010, 9:00am CDT

Condition: AML
Intervention: Drug: Sirolimus
Sponsors: Thomas Jefferson University; University of Pennsylvania
Recruiting - verified August 2010
$Permalink for 'A Phase I Study of IMC-A12 in Combination With Temsirolimus in Pediatric Patients With Recurrent or Refractory Solid Tumors'$
A Phase I Study of IMC-A12 in Combination With Temsirolimus in Pediatric Patients With Recurrent or Refractory Solid Tumors

Posted: August 14th, 2010, 9:00am CDT

Conditions: Brain Stem Neoplasms; Glioma; Pinealoma
Interventions: Drug: IMC-A12; Drug: Temsirolimus
Sponsor: National Cancer Institute (NCI)
Recruiting - verified July 2010
A Pase II Trial of Valproic Acid in Patients With Advanced Thyroid Cancers of Follicular Cell Origin

Posted: August 13th, 2010, 9:00am CDT

Condition: Thyroid Neoplasm
Intervention: Drug: Valproic Acid
Sponsor: National Cancer Institute (NCI)
Recruiting - verified December 2009
$Permalink for 'Penostatin, Rituximab and Ontak and Allogeneic Natural Killer (NK) Cells for Refractory Lymphoid Malignancies'$
Penostatin, Rituximab and Ontak and Allogeneic Natural Killer (NK) Cells for Refractory Lymphoid Malignancies

Posted: August 12th, 2010, 9:00am CDT

Conditions: Relapsed Lymphoma; B Cell Non-Hodgkin Lymphoma; Refractory Lymphoma; High Risk Chronic Lymphocytic Leukemia
Interventions: Drug: Pentostatin; Drug: Rituximab; Drug: Denileukin Diftitox; Biological: Interleukin-2; Biological: Natural killer cells
Sponsor: Masonic Cancer Center, University of Minnesota
Recruiting - verified August 2010
Sequential Myeloablative Autologous Stem Cell Transplantation Followed by Allogeneic Non-Myeloablative Stem Cell Transplantation for Patients With Poor Risk Lymphomas

Posted: August 12th, 2010, 9:00am CDT

Conditions: Diffuse, Large B-Cell, Lymphoma; Lymphoma, Low-Grade; T-Cell Lymphoma; Mantle-Cell Lymphoma; Hodgkin's Lymphoma; Chronic Lymphocytic Leukemia; Lymphoma, Small Lymphocytic
Interventions: Drug: Busulfan; Drug: Etoposide; Drug: Cyclophosphamide; Drug: Mesna; Drug: Phenytoin; Drug: Ursodiol; Other: Infusion of autologous peripheral blood stem cells; Drug: Neupogen; Drug: Fludarabine; Drug: Busulfan; Other: Peripheral blood stem cell transplant; Drug: Tacrolimus; Drug: Sirolimus; Drug: Methotrexate
Sponsors: Massachusetts General Hospital; Dana-Farber Cancer Institute
Recruiting - verified August 2010
Trial Of Super-Selective Intraarterial Cerebral Infusion Of Temozolomide (TEMODAR) For Treatment Of Newly Diagnosed Glioblastoma Multiforme And Anaplastic Astrocytoma

Posted: August 10th, 2010, 9:00am CDT

Conditions: Glioblastoma Multiforme; Anaplastic Astrocytoma
Intervention: Drug: Super-Selective Intraarterial Intracranial Infusion of Temozolomide
Sponsor: Weill Medical College of Cornell University
Recruiting - verified August 2010
The Effect of Adding Intraoperative Regional Anesthesia on Cancer Recurrence in Patients Undergoing Lung Cancer Resection

Posted: August 10th, 2010, 9:00am CDT

Condition: Lung Cancer
Interventions: Other: General-epidural anesthesia and analgesia; Other: Balanced general anesthesia and postoperative opioids
Sponsor: Outcomes Research Consortium
Recruiting - verified August 2010
New Treatment for Alcohol and Nicotine Dependence

Posted: August 10th, 2010, 9:00am CDT

Conditions: Alcohol Dependence; Nicotine Dependence
Interventions: Drug: Topiramate with brief behavioral enhancement therapy; Drug: Placebo plus brief behavioral enhancement therapy
Sponsors: University of Virginia; National Institute on Alcohol Abuse and Alcoholism (NIAAA); University of Houston; University of Cincinnati; M.D. Anderson Cancer Center
Not yet recruiting - verified August 2010
Vorinostat in Treating Patients With Locally Advanced, Recurrent, or Metastatic Adenoid Cystic Carcinoma

Posted: August 4th, 2010, 9:00am CDT

Condition: Head and Neck Cancer
Interventions: Drug: vorinostat; Other: laboratory biomarker analysis
Sponsors: Barbara Ann Karmanos Cancer Institute; National Cancer Institute (NCI)
Not yet recruiting - verified August 2010
Aprepitant and Granisetron for the Prophylaxis of Radiation Induced Nausea and Vomiting - A Pilot Study

Posted: August 4th, 2010, 9:00am CDT

Conditions: Nausea; Vomiting
Intervention: Drug: Aprepitant
Sponsors: Sunnybrook Health Sciences Centre; Merck Frosst Canada Ltd.
Not yet recruiting - verified August 2010
A Clinical Trial of COX and EGFR Inhibition in Familial Polyposis Patients

Posted: August 3rd, 2010, 9:00am CDT

Condition: Adenomatous Polyposis Coli
Interventions: Drug: Erlotinib; Drug: Sulindac; Drug: Placebo A; Drug: Placebo B
Sponsors: University of Utah; National Cancer Institute (NCI)
Recruiting - verified August 2010
$Permalink for 'Bortezomib and Midostaurin With or Without Combination Chemotherapy in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia'$
Bortezomib and Midostaurin With or Without Combination Chemotherapy in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia

Posted: August 2nd, 2010, 9:00am CDT

Conditions: Acute Myeloid Leukemia; Acute Myeloid Leukemia With Multilineage Dysplasia Following; Myelodysplastic Syndrome; Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities; Adult Acute Myeloid Leukemia With Del(5q); Adult Acute Myeloid Leukemia With Inv(16)(p13;q22); Adult Acute Myeloid Leukemia With T(15;17)(q22;q12); Adult Acute Myeloid Leukemia With T(16;16)(p13;q22); Adult Acute Myeloid Leukemia With T(8;21)(q22;q22); Recurrent Adult Acute Myeloid Leukemia; Secondary Acute Myeloid Leukemia
Interventions: Drug: midostaurin, bortezomib,; Drug: mitoxantrone hydrochloride, etoposide, cytarabine, midostaurin, bortezomib
Sponsor: Ohio State University Comprehensive Cancer Center
Not yet recruiting - verified August 2010
Efficacy Study of SyB L-0501 for Patients With Multiple Myeloma

Posted: August 2nd, 2010, 9:00am CDT

Condition: Multiple Myeloma
Interventions: Drug: SyB L-0501; Drug: prednisolone
Sponsor: SymBio Pharmaceuticals
Recruiting - verified August 2010
Maintenance Treatment for Ovarian Carcinoma in Remission by an Antiangiogenic Treatment Strategy

Posted: August 1st, 2010, 9:00am CDT

Condition: Ovarian Carcinoma
Intervention: Drug: Cytophosphan, Celecoxib, Methotrexate
Sponsor: HaEmek Medical Center, Israel
Recruiting - verified August 2010
Temsirolimus and Vorinostat in Treating Patients With Metastatic Prostate Cancer

Posted: July 30th, 2010, 9:00am CDT

Conditions: Prostate Cancer; Adenocarcinoma of the Prostate; Hormone-resistant Prostate Cancer; Recurrent Prostate Cancer; Stage IV Prostate Cancer
Interventions: Drug: vorinostat; Drug: temsirolimus; Other: laboratory biomarker analysis; Procedure: positron emission tomography/computed tomography
Sponsor: Roswell Park Cancer Institute
Not yet recruiting - verified July 2010
High-Dose Chemotherapy and Stem Cell Transplant in Treating Patients With Metastatic Germ Cell Tumors That Have Not Responded to First-Line Therapy

Posted: July 29th, 2010, 9:00am CDT

Conditions: Brain and Central Nervous System Tumors; Extragonadal Germ Cell Tumor; Testicular Germ Cell Tumor
Interventions: Biological: filgrastim; Biological: pegfilgrastim; Drug: carboplatin; Drug: cisplatin; Drug: dexamethasone; Drug: etoposide; Drug: ifosfamide; Other: high-dose chemotherapy with autologous stem cell rescue; Other: laboratory biomarker analysis; Procedure: autologous hematopoietic stem cell transplantation; Procedure: peripheral blood stem cell transplantation
Sponsor: Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Not yet recruiting - verified July 2010
A Study Evaluating INIPARIB in Combination With Chemotherapy to Treat Triple Negative Breast Cancer Brain Metastasis

Posted: July 28th, 2010, 9:00am CDT

Conditions: Estrogen Receptor Negative (ER-Negative) Breast Cancer; Progesterone Receptor Negative (PR-Negative) Breast Cancer; Human Epidermal Growth Factor Receptor 2 Negative (HER2-Negative) Breast Cancer; Brain Metastases
Intervention: Drug: INIPARIB + irinotecan
Sponsors: BiPar Sciences; UNC Lineberger Comprehensive Cancer Center
Recruiting - verified July 2010
Genetically-modified Neural Stem Cells (NSCs) and 5-Fluorocytosine in Treating Patients Undergoing Surgery For Recurrent High Grade Gliomas

Posted: July 28th, 2010, 9:00am CDT

Conditions: Adult Anaplastic Astrocytoma; Recurrent Grade III Glioma; Recurrent Grade IV Glioma; Adult Anaplastic Oligodendroglioma; Adult Brain Tumor; Adult Giant Cell Glioblastoma; Adult Glioblastoma; Adult Gliosarcoma; Adult Mixed Glioma; Recurrent Adult Brain Tumor; Adult Anaplastic Oligoastrocytoma; Recurrent High Grade Glioma
Interventions: Drug: flucytosine; Other: polymerase chain reaction; Other: immunohistochemistry staining method; Biological: gene therapy; Other: pharmacological study; Other: 3-Tesla magnetic resonance imaging; Other: laboratory biomarker analysis; Procedure: therapeutic conventional surgery; Biological: E. coli CD-expressing genetically modified neural stem cells
Sponsor: City of Hope Medical Center
Recruiting - verified August 2010
Vaccination With Dendritic Cells Loaded With Brain Tumor Stem Cells for Progressive Malignant Brain Tumor

Posted: July 27th, 2010, 9:00am CDT

Conditions: Brain Tumor; Glioblastoma; Medulloblastoma; Ependymoma
Interventions: Biological: Dendritic Cells; Drug: Imiquimod
Sponsor: Masonic Cancer Center, University of Minnesota
Not yet recruiting - verified July 2010
Timely End-of-Life Communication to Parents of Children With Brain Tumors

Posted: July 26th, 2010, 9:00am CDT

Conditions: Palliative Care; Communication
Intervention:
Sponsors: Barnes-Jewish Hospital Foundation; National Institute of Nursing Research (NINR)
Recruiting - verified July 2010
Study of PEGPH20 With Initial Dexamethasone Premedication Given Intravenously to Patients With Advanced Solid Tumors

Posted: July 26th, 2010, 9:00am CDT

Condition: Solid Tumor
Intervention: Drug: PEGPH20
Sponsor: Halozyme Therapeutics
Recruiting - verified July 2010
Nuvigil in Treatment of Cancer-Related Fatigue in Chronic Myeloid Leukemia Patients

Posted: July 23rd, 2010, 9:00am CDT

Condition: Chronic Myeloid Leukemia
Interventions: Other: Placebo; Drug: Armodafinil
Sponsor: M.D. Anderson Cancer Center
Not yet recruiting - verified July 2010
$Permalink for 'Exclusive Hypofractionated Stereotactic Radiotherapy in Non-resectable Single Brain Metastasis'$
Exclusive Hypofractionated Stereotactic Radiotherapy in Non-resectable Single Brain Metastasis

Posted: July 22nd, 2010, 9:00am CDT

Conditions: Cancer; Metastasis
Intervention: Radiation: hypofractionated stereotactic radiotherapy
Sponsor: Barretos Cancer Hospital
Recruiting - verified July 2010
A Phase I Study of Ridaforolimus and Vorinostat in Patients With Advanced Renal Cell Carcinoma (RCC)

Posted: July 22nd, 2010, 9:00am CDT

Condition: Advanced Renal Cell Carcinoma
Interventions: Drug: Vorinostat; Drug: Ridaforolimus
Sponsors: Fox Chase Cancer Center; Merck
Not yet recruiting - verified July 2010
$Permalink for 'Bendamustine Plus Bortezomib Plus Dexamethasone in Relapsed or Refractory Multiple Myeloma'$
Bendamustine Plus Bortezomib Plus Dexamethasone in Relapsed or Refractory Multiple Myeloma

Posted: July 22nd, 2010, 9:00am CDT

Conditions: Multiple Myeloma; Bendamustine; Bortezomib; Dexamethasone
Intervention: Drug: bendamustine plus bortezomib plus dexamethasone
Sponsor: Austrian Forum Against Cancer
Recruiting - verified August 2010
Carbon Ion Radiotherapy for Atypical Meningiomas

Posted: July 20th, 2010, 9:00am CDT

Condition: Meningioma
Intervention: Radiation: Carbon Ion Radiotherapy
Sponsor: University Hospital Heidelberg
Not yet recruiting - verified July 2010
Temozolomide With or Without Bevacizumab in Treating Patients With Recurrent Glioma

Posted: July 15th, 2010, 9:00am CDT

Condition: Brain and Central Nervous System Tumors
Interventions: Biological: bevacizumab; Drug: temozolomide; Other: laboratory biomarker analysis
Sponsor: European Organization for Research and Treatment of Cancer
Not yet recruiting - verified July 2010
A Safety and Efficacy Study of JNS024 Extended Release (ER) in Japanese and Korean Patients With Chronic Malignant Tumor-Related Cancer Pain

Posted: July 15th, 2010, 9:00am CDT

Condition: Pain
Interventions: Drug: Oxycodone CR; Drug: R331333 (referred to as JNS024 ER or CG5503)
Sponsor: Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Not yet recruiting - verified August 2010
Trial of Ascertaining Individual Preferences for Loved One's Role in End-of-Life

Posted: July 9th, 2010, 9:00am CDT

Conditions: Amyotrophic Lateral Sclerosis; GI Cancer; Pancreatic Cancer
Interventions: Other: TAILORED Patient Family Decision Making; Other: standard of care
Sponsors: Johns Hopkins University; University of Chicago
Recruiting - verified July 2010
Curcumin Biomarker Trial in Head and Neck Cancer

Posted: July 8th, 2010, 9:00am CDT

Condition: Head and Neck Cancer
Intervention: Dietary Supplement: Microgranular Curcumin C3 Complex®
Sponsors: Louisiana State University - Shreveport; Feist-Weiller Cancer Center at Louisiana State University Health Sciences; National Cancer Institute (NCI)
Recruiting - verified November 2009
$Permalink for 'PTC299 in Treating Young Patients With Refractory or Recurrent Primary Central Nervous System Tumors'$
PTC299 in Treating Young Patients With Refractory or Recurrent Primary Central Nervous System Tumors

Posted: July 7th, 2010, 9:00am CDT

Conditions: Brain and Central Nervous System Tumors; Childhood Germ Cell Tumor; Lymphoma; Sarcoma
Interventions: Drug: VEGF inhibitor PTC299; Other: enzyme-linked immunosorbent assay; Other: laboratory biomarker analysis; Other: pharmacological study
Sponsors: Pediatric Brain Tumor Consortium; National Cancer Institute (NCI); PTC Therapeutics Incorporated
Not yet recruiting - verified July 2010
$Permalink for 'RO4929097 and Capecitabine in Treating Patients With Refractory Solid Tumors'$
RO4929097 and Capecitabine in Treating Patients With Refractory Solid Tumors

Posted: July 7th, 2010, 9:00am CDT

Conditions: Brain and Central Nervous System Tumors; Breast Cancer; Colorectal Cancer; Lymphoma; Lymphoproliferative Disorder; Small Intestine Cancer; Unspecified Adult Solid Tumor, Protocol Specific
Interventions: Drug: capecitabine; Drug: gamma-secretase inhibitor RO4929097; Other: laboratory biomarker analysis; Other: pharmacogenomic studies; Other: pharmacological study
Sponsors: University of Wisconsin, Madison; National Cancer Institute (NCI)
Recruiting - verified July 2010
A Study of the Effectiveness of Armodafinil to Treat Cancer-Related Fatigue in Patients With Multiple Myeloma

Posted: July 7th, 2010, 9:00am CDT

Conditions: Fatigue; Multiple Myeloma
Interventions: Drug: armodafinil; Drug: Placebo
Sponsors: Oncotherapeutics; Cephalon
Recruiting - verified July 2010
$Permalink for 'A Study of Pegylated Liposomal Doxorubicin (PLD), Bortezomib, Dexamethasone and Lenalidomide for Patients With Relapsed/Refractory Multiple Myeloma'$
A Study of Pegylated Liposomal Doxorubicin (PLD), Bortezomib, Dexamethasone and Lenalidomide for Patients With Relapsed/Refractory Multiple Myeloma

Posted: July 7th, 2010, 9:00am CDT

Condition: Relapsed/Refractory Multiple Myeloma
Intervention: Drug: DVD-R
Sponsors: Oncotherapeutics; Celgene Corporation
Recruiting - verified July 2010
Celecoxib and Recombinant Interferon Alfa-2b in Treating Patients With Metastatic Kidney Cancer Who Have Undergone Surgery

Posted: July 6th, 2010, 9:00am CDT

Conditions: Renal Cell Cancer; Stage IV Renal Cell Cancer
Interventions: Drug: celecoxib; Biological: recombinant interferon alfa-2b; Other: polymerase chain reaction; Other: laboratory biomarker analysis; Other: reverse transcriptase-polymerase chain reaction; Other: immunologic technique; Other: immunohistochemistry staining method; Other: flow cytometry
Sponsor: Case Comprehensive Cancer Center
Recruiting - verified July 2010
Methylphenidate for Cancer-Related Fatigue

Posted: July 6th, 2010, 9:00am CDT

Condition: Cancer
Intervention: Drug: methylphenidate
Sponsors: Dana-Farber Cancer Institute; Children's Hospital Boston
Not yet recruiting - verified July 2010
Efficacy of Bispectral Index Monitoring for Midazolam and Meperidine Induced Sedation During Endoscopic Submucosal Dissection

Posted: July 5th, 2010, 9:00am CDT

Conditions: Gastric Adenoma; Gastric Cancer
Intervention: Device: bispectral index monitoring
Sponsor: Samsung Medical Center
Recruiting - verified July 2010
Combination Chemotherapy in Treating Young Adult Patients With Acute Lymphoblastic Leukemia

Posted: July 2nd, 2010, 9:00am CDT

Condition: Leukemia
Interventions: Drug: asparaginase; Drug: cyclophosphamide; Drug: cytarabine; Drug: daunorubicin hydrochloride; Drug: dexamethasone; Drug: doxorubicin hydrochloride; Drug: ifosfamide; Drug: mercaptopurine; Drug: methotrexate; Drug: methylprednisolone; Drug: prednisone; Drug: thioguanine; Drug: vincristine sulfate; Drug: vindesine
Sponsor: Gruppo Italiano Malattie EMatologiche dell'Adulto
Recruiting - verified July 2010
Doxepin Hydrochloride in Treating Oral Mucositis Pain in Patients With Head and Neck Cancer Undergoing Radiation Therapy With or Without Chemotherapy

Posted: July 1st, 2010, 9:00am CDT

Conditions: Head and Neck Cancer; Mucositis; Oral Complications of Radiation Therapy; Pain
Interventions: Drug: doxepin hydrochloride; Other: placebo
Sponsors: North Central Cancer Treatment Group; National Cancer Institute (NCI)
Not yet recruiting - verified June 2010
$Permalink for 'Low-Dose Azacitidine, Lenalidomide, and Low-Dose Dexamethasone in Treating Patients With Relapsed or Refractory Multiple Myeloma'$
Low-Dose Azacitidine, Lenalidomide, and Low-Dose Dexamethasone in Treating Patients With Relapsed or Refractory Multiple Myeloma

Posted: June 30th, 2010, 9:00am CDT

Condition: Refractory Multiple Myeloma
Interventions: Drug: azacitidine; Drug: lenalidomide; Drug: dexamethasone; Other: DNA methylation analysis; Other: gene expression analysis; Other: bone marrow aspiration; Other: immunohistochemistry staining method; Other: reverse transcriptase-polymerase chain reaction; Other: flow cytometry
Sponsors: Case Comprehensive Cancer Center; National Cancer Institute (NCI)
Recruiting - verified June 2010
Everolimus and Mitoxantrone Hydrochloride, Cytarabine, Etoposide, and Idarubicin in Treating Older Patients With Newly Diagnosed Acute Myeloid Leukemia

Posted: June 29th, 2010, 9:00am CDT

Condition: Leukemia
Interventions: Drug: cytarabine; Drug: etoposide; Drug: everolimus; Drug: idarubicin; Drug: mitoxantrone hydrochloride
Sponsor: Gruppo Italiano Malattie EMatologiche dell'Adulto
Recruiting - verified July 2010
Theca Cell Function in Adolescents With Polycystic Ovary Syndrome (PCOS)

Posted: June 29th, 2010, 9:00am CDT

Condition: PCOS
Intervention: Drug: Dexamethasone and recombinant hCG
Sponsors: University of California, San Diego; University of Virginia
Recruiting - verified January 2010
Effects of Steroid Tapering on Functional Capacity and Neurocognition

Posted: June 25th, 2010, 9:00am CDT

Condition: Glioblastoma Multiforme
Interventions: Drug: Dexamethasone acetate; Drug: Dexamethasone
Sponsor: Duke University
Not yet recruiting - verified July 2010
Clinical Trial to Assess the Immunogenicity and Safety of the Vero Cell-derived JE Vaccine in Korea

Posted: June 24th, 2010, 9:00am CDT

Condition: Japanese Encephalitis
Intervention: Biological: JE vaccine
Sponsors: Boryung Pharmaceutical Co., Ltd; Seoul National University Hospital; Gachon University Gil Medical Center; Inha University Hospital; Inje University; Korea Cancer Center Hospital; Samsung Medical Center; The Catholic University of Korea; Ewha Womans University
Not yet recruiting - verified June 2010
Oxaliplatin, Leucovorin Calcium, and Fluorouracil With or Without Celecoxib in Treating Patients With Stage III Colon Cancer Previously Treated With Surgery

Posted: June 23rd, 2010, 9:00am CDT

Condition: Colorectal Cancer
Interventions: Drug: celecoxib; Drug: fluorouracil; Drug: leucovorin calcium; Drug: oxaliplatin; Other: placebo
Sponsors: Cancer and Leukemia Group B; National Cancer Institute (NCI)
Recruiting - verified August 2010
Vorinostat in Treating Patients With Stage IV Breast Cancer Receiving Aromatase Inhibitor Therapy

Posted: June 22nd, 2010, 9:00am CDT

Conditions: Male Breast Cancer; Recurrent Breast Cancer; Stage IV Breast Cancer
Interventions: Drug: vorinostat; Other: laboratory biomarker analysis; Procedure: biopsy; Radiation: F-18 16 alpha-fluoroestradiol; Procedure: positron emission tomography; Drug: anastrozole; Drug: letrozole; Drug: exemestane; Genetic: gene expression analysis
Sponsor: Fred Hutchinson Cancer Research Center
Not yet recruiting - verified August 2010
Aminolevulinic Acid During Surgery in Treating Patients With Malignant Brain Tumors

Posted: June 21st, 2010, 9:00am CDT

Conditions: Adult Anaplastic Astrocytoma; Adult Anaplastic Oligodendroglioma; Adult Giant Cell Glioblastoma; Adult Glioblastoma; Adult Gliosarcoma; Adult Mixed Glioma; Recurrent Adult Brain Tumor
Interventions: Drug: aminolevulinic acid; Other: laboratory biomarker analysis; Procedure: therapeutic conventional surgery
Sponsor: Fred Hutchinson Cancer Research Center
Not yet recruiting - verified July 2010
High-dose Chemotherapy and Stem Cell Transplantation for Central Nervous System (CNS) Relapse of Aggressive Lymphomas

Posted: June 21st, 2010, 9:00am CDT

Condition: Lymphoma, Non-Hodgkin
Intervention: Drug: Combined systemic and intrathecal chemotherapy followed by HD-ASCT
Sponsor: Charite University, Berlin, Germany
Recruiting - verified November 2007
$Permalink for 'Study of Decadron, Biaxin, and Pomalidomide in Relapsed/Refractory Myeloma'$
Study of Decadron, Biaxin, and Pomalidomide in Relapsed/Refractory Myeloma

Posted: June 16th, 2010, 9:00am CDT

Condition: Multiple Myeloma
Interventions: Drug: dexamethasone; Drug: clarithromycin; Drug: Pomalidomide
Sponsors: Weill Medical College of Cornell University; Celgene Corporation
Recruiting - verified August 2010
A Study of MabThera (Rituximab) Addition to Regularly Prescribed Chemotherapy in Patients With Untreated Mantle Cell Lymphoma

Posted: June 14th, 2010, 9:00am CDT

Condition: Lymphoma, B-Cell
Interventions: Drug: rituximab [Mabthera/Rituxan]; Drug: fludarabine; Drug: cyclophosphamide; Drug: mitoxantrone
Sponsor: Hoffmann-La Roche
Not yet recruiting - verified August 2010
Nimotuzumab and Radiotherapy in Pediatric Patients With Glioma

Posted: June 14th, 2010, 9:00am CDT

Condition: Diffuse Intrinsic Brainstem Gliomas
Interventions: Radiation: Radiotherapy; Biological: Nimotuzumab
Sponsors: Eurofarma Laboratorios Ltda; CIM; CENCEC
Not yet recruiting - verified June 2010
Pilot Study of Allogeneic Tumor Cell Vaccine With Metronomic Oral Cyclophosphamide and Celecoxib in Patients Undergoing Resection of Lung and Esophageal Cancers, Thymic Neoplasms, and Malignant Pleural Mesotheliomas

Posted: June 11th, 2010, 9:00am CDT

Conditions: Lung Cancer; Esophageal Cancer; Malignant Pleural Mesothelioma; Thymoma; Thymic Carcinoma
Interventions: Biological: Allogeneic Tumor Cell Vaccine (K562); Drug: Celecoxib; Drug: cyclophosphamide
Sponsor: National Cancer Institute (NCI)
Recruiting - verified May 2010
$Permalink for 'A Phase I Study of Vorinostat and Bortezomib in Children With Refractory of Recurrent Solid Tumors, Including CNS Tumors and Lymphomas'$
A Phase I Study of Vorinostat and Bortezomib in Children With Refractory of Recurrent Solid Tumors, Including CNS Tumors and Lymphomas

Posted: May 27th, 2010, 9:00am CDT

Conditions: Lymphoma; Sarcoma; WilmsTumor; Neuroblastoma
Interventions: Drug: Vorinostat (SAHA); Drug: Velcade (PS-341, Bortezomib)
Sponsor: National Cancer Institute (NCI)
Recruiting - verified April 2010
Gamma-Secretase Inhibitor RO4929097 and Cediranib Maleate in Treating Patients With Advanced Solid Tumors

Posted: May 25th, 2010, 9:00am CDT

Conditions: Brain and Central Nervous System Tumors; Breast Cancer; Colorectal Cancer; Kidney Cancer; Lung Cancer; Melanoma (Skin); Ovarian Cancer; Pancreatic Cancer; Unspecified Adult Solid Tumor, Protocol Specific
Interventions: Drug: cediranib maleate; Drug: gamma-secretase inhibitor RO4929097; Other: laboratory biomarker analysis; Other: pharmacological study
Sponsors: Princess Margaret Hospital, Canada; National Cancer Institute (NCI)
Recruiting - verified August 2010
$Permalink for 'Decitabine, Vorinostat, and Cytarabine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia'$
Decitabine, Vorinostat, and Cytarabine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia

Posted: May 25th, 2010, 9:00am CDT

Condition: Leukemia
Interventions: Drug: cytarabine; Drug: decitabine; Drug: vorinostat; Genetic: gene expression analysis; Genetic: protein expression analysis; Other: laboratory biomarker analysis; Other: pharmacological study
Sponsors: Arthur G. James Cancer Hospital & Richard J. Solove Research Institute; National Cancer Institute (NCI)
Not yet recruiting - verified May 2010
$Permalink for 'A Phase I Study of Pazopanib as a Single Agent for Children With Refractory Solid Tumors'$
A Phase I Study of Pazopanib as a Single Agent for Children With Refractory Solid Tumors

Posted: May 25th, 2010, 9:00am CDT

Conditions: Sarcoma; Neuroblastoma; Wilms Tumor; Osteosarcoma; Brain Tumor
Intervention: Drug: Pazopanib (GW786034)
Sponsor: National Cancer Institute (NCI)
Recruiting - verified April 2010
$Permalink for 'Bortezomib, Mitoxantrone, Etoposide, and Cytarabine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia'$
Bortezomib, Mitoxantrone, Etoposide, and Cytarabine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia

Posted: May 19th, 2010, 9:00am CDT

Conditions: Adult Acute Megakaryoblastic Leukemia (M7); Adult Acute Minimally Differentiated Myeloid Leukemia (M0); Adult Acute Monoblastic Leukemia (M5a); Adult Acute Monocytic Leukemia (M5b); Adult Acute Myeloblastic Leukemia With Maturation (M2); Adult Acute Myeloblastic Leukemia Without Maturation (M1); Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities; Adult Acute Myeloid Leukemia With Del(5q); Adult Acute Myeloid Leukemia With Inv(16)(p13;q22); Adult Acute Myeloid Leukemia With T(16;16)(p13;q22); Adult Acute Myeloid Leukemia With T(8;21)(q22;q22); Adult Acute Myelomonocytic Leukemia (M4); Adult Erythroleukemia (M6a); Adult Pure Erythroid Leukemia (M6b); Recurrent Adult Acute Myeloid Leukemia
Interventions: Drug: bortezomib; Drug: mitoxantrone hydrochloride; Drug: etoposide; Drug: cytarabine; Other: flow cytometry
Sponsor: Case Comprehensive Cancer Center
Recruiting - verified July 2010
A Study of the Specificity and Sensitivity of 5- Aminolevulinic Acid (ALA) Fluorescence in Malignant Brain Tumors

Posted: May 13th, 2010, 9:00am CDT

Condition: Brain Neoplasms
Intervention: Drug: 5-aminolevulinic acid
Sponsors: Southern Illinois University; Memorial Medical Center; DUSA Pharmaceuticals, Inc.
Not yet recruiting - verified August 2010
131I-L19SIP Radioimmunotherapy (RIT) in Combination With External Beam Radiation in Patients With Multiple Brain Metastases From Solid Tumors

Posted: May 12th, 2010, 9:00am CDT

Condition: Brain Metastases From Solid Tumors
Intervention: Radiation: 131I-L19SIP Radioimmunotherapy (RIT) in Combination With Whole Brain Radiation Therapy (WBRT)
Sponsor: Philogen S.p.A.
Recruiting - verified July 2010
RO4929097 in Treating Patients With Recurrent or Progressive Glioblastoma

Posted: May 11th, 2010, 9:00am CDT

Condition: Brain and Central Nervous System Tumors
Interventions: Drug: gamma-secretase inhibitor RO4929097; Other: laboratory biomarker analysis; Other: pharmacological study; Procedure: adjuvant therapy; Procedure: neoadjuvant therapy; Procedure: therapeutic conventional surgery
Sponsor: National Cancer Institute (NCI)
Not yet recruiting - verified August 2010
Prospective Randomized Comparative Study of Cell Transfer Therapy Using CD8+-Enriched Short-Term Cultured Anti-Tumor Autologous Lymphocytes Following a Non-Myeloablative Lymphocyte Depleting Chemotherapy Regimen Compared to High-Dose Aldesleukin in M...

Posted: May 5th, 2010, 9:00am CDT

Conditions: Skin Cancer; Melanoma; Metastatic Melanoma
Interventions: Biological: Aldesleukin; Biological: CD8 enriched Young TIL
Sponsor: National Cancer Institute (NCI)
Recruiting - verified April 2010
Safety Study of Aminolevulinic Acid (ALA) to Enhance Visualization and Resection of Malignant Tumors of the Brain

Posted: May 3rd, 2010, 9:00am CDT

Condition: Glioma
Intervention: Drug: 5-Aminolevuline Acid
Sponsor: University of California, San Francisco
Recruiting - verified August 2010
Long-Term Study of Hydrocodone Bitartrate Controlled-release Capsules in Subjects With Chronic Pain

Posted: April 30th, 2010, 9:00am CDT

Condition: Chronic Pain
Intervention: Drug: Hydrocodone bitartrate
Sponsor: Zogenix, Inc.
Recruiting - verified August 2010
High Dose Chemotherapy and Stem Cell Transplant for Non-Hodgkin's Lymphoma or Central Nervous System (CNS) Lymphoma

Posted: April 30th, 2010, 9:00am CDT

Conditions: Non-Hodgkin's Lymphoma; CNS Lymphoma
Intervention: Procedure: High-dose chemotherapy with autologous stem cell transplant
Sponsors: Massachusetts General Hospital; Genentech; Otsuka America Pharmaceutical; Dana-Farber Cancer Institute
Recruiting - verified August 2010
AMG 102 and Avastin for Recurrent Malignant Glioma

Posted: April 28th, 2010, 9:00am CDT

Conditions: Grade IV Malignant Glioma; Glioblastoma Multiforme; Gliosarcoma
Intervention: Drug: AMG 102 plus Avastin (bevacizumab)
Sponsors: Duke University; Amgen
Recruiting - verified August 2010
TPI 287 in Patients With Recurrent Glioblastoma Multiforme

Posted: April 27th, 2010, 9:00am CDT

Condition: Brain Cancer
Intervention: Drug: TPI 287
Sponsors: M.D. Anderson Cancer Center; Archer Biosciences, Inc.
Recruiting - verified August 2010
Vorinostat, Erlotinib and Carboplatin for Recurrent Glioblastoma Multiforme

Posted: April 22nd, 2010, 9:00am CDT

Conditions: Brain Cancer; Glioblastoma Multiforme
Interventions: Drug: Vorinostat; Drug: Erlotinib; Drug: Carboplatin
Sponsors: M.D. Anderson Cancer Center; Merck
Not yet recruiting - verified August 2010
Comprehensive Omics Analysis of Pediatric Solid Tumors and Establishment of a Repository for Related Biological Studies

Posted: April 22nd, 2010, 9:00am CDT

Conditions: Sarcoma; Endocrine Tumors; Neuroblastoma; Retinoblastoma; Renal Cancer
Intervention:
Sponsor: National Cancer Institute (NCI)
Recruiting - verified March 2010
$Permalink for 'Haploidentical Natural Killer Cells to Treat Refractory or Relapsed Acute Myelogenous Leukemia (AML)'$
Haploidentical Natural Killer Cells to Treat Refractory or Relapsed Acute Myelogenous Leukemia (AML)

Posted: April 19th, 2010, 9:00am CDT

Condition: Leukemia, Myelogenous, Acute
Interventions: Biological: Natural Killer Cells; Drug: Fludarabine; Drug: Cyclophosphamide; Drug: Denileukin diftitox; Procedure: Donor lymphapheresis; Drug: IL-2
Sponsor: Masonic Cancer Center, University of Minnesota
Recruiting - verified July 2010
Study Comparing Conventional Dose Combination RVD to High-Dose Treatment With ASCT in the Initial Myeloma up to 65 Years

Posted: April 16th, 2010, 9:00am CDT

Conditions: Patients Newly Diagnosed With Symptomatic Multiple Myeloma; Patients Aged up to 65 Years; Progression Free Survival Prolongation; Time to Progression; Overall Survival
Interventions: Drug: Lenalidomide, Bortézomib; Drug: Lenalidomide, Bortézomib
Sponsors: University Hospital, Toulouse; Dana-Farber Cancer Institute; Celgene Corporation; Janssen-Cilag Ltd.
Not yet recruiting - verified August 2010
Allogeneic Natural Killer (NK) Cells for Ovarian, Fallopian Tube, Peritoneal and Metastatic Breast Cancer

Posted: April 14th, 2010, 9:00am CDT

Conditions: Ovarian Cancer; Fallopian Tube Cancer; Primary Peritoneal Cancer; Breast Cancer
Interventions: Drug: Fludarabine; Drug: Cyclophosphamide; Drug: Cyclosporine; Biological: Natural killer cells; Drug: IL-2
Sponsor: Masonic Cancer Center, University of Minnesota
Recruiting - verified July 2010
Study of Administration of CMV-specific Cytotoxic T Lymphocytes Expressing CAR Targeting HER2 in Patients With GBM

Posted: April 13th, 2010, 9:00am CDT

Condition: Brain Cancer
Intervention: Drug: HER.CAR CMV-specific CTL
Sponsors: Baylor College of Medicine; The Methodist Hospital System; Center for Cell and Gene Therapy, Baylor College of Medicine
Not yet recruiting - verified July 2010
Granulocyte-macrophage Colony-stimulating Factor, Interferon and Interleukin-2 as Adjuvant Treatment for Renal Cancer

Posted: April 13th, 2010, 9:00am CDT

Condition: Renal Cell Carcinoma
Intervention: Drug: GM-CSF, IFN alpha and IL-2
Sponsor: Kidney Cancer Research Bureau
Recruiting - verified August 2010
Study Evaluating the Safety and Effectiveness of Etanercept for the Treatment of Pediatric Psoriasis

Posted: April 6th, 2010, 9:00am CDT

Condition: Psoriasis
Intervention: Drug: Etanercept
Sponsor: Wyeth
Recruiting - verified July 2010
$Permalink for 'Aplidin - Dexamethasone in Relapsed/Refractory Myeloma'$
Aplidin - Dexamethasone in Relapsed/Refractory Myeloma

Posted: March 31st, 2010, 9:00am CDT

Condition: Relapsed/Refractory Multiple Myeloma
Interventions: Drug: plitidepsin + dexamethasone; Drug: dexamethasone
Sponsor: PharmaMar
Recruiting - verified August 2010
Maintenance Chemotherapy or Observation Following Induction Chemotherapy and Radiation Therapy in Treating Younger Patients With Newly Diagnosed Ependymoma

Posted: March 30th, 2010, 9:00am CDT

Condition: Brain and Central Nervous System Tumors
Interventions: Drug: cisplatin; Drug: cyclophosphamide; Drug: etoposide; Drug: vincristine sulfate; Other: clinical observation; Radiation: 3-dimensional conformal radiation therapy
Sponsors: Children's Oncology Group; National Cancer Institute (NCI)
Recruiting - verified August 2010
Rituximab, Combination Chemotherapy, Filgrastim (G-CSF), and Plerixafor in Treating Patients With Non-Hodgkin Lymphoma Undergoing Mobilization of Autologous Peripheral Blood Stem Cells

Posted: March 30th, 2010, 9:00am CDT

Conditions: Adult Non-Hodgkin Lymphoma; Adult Grade III Lymphomatoid Granulomatosis; Contiguous Stage II Adult Burkitt Lymphoma; Contiguous Stage II Adult Diffuse Large Cell Lymphoma; Contiguous Stage II Adult Diffuse Mixed Cell Lymphoma; Contiguous Stage II Adult Diffuse Small Cleaved Cell Lymphoma; Contiguous Stage II Adult Immunoblastic Large Cell Lymphoma; Contiguous Stage II Adult Lymphoblastic Lymphoma; Contiguous Stage II Grade 1 Follicular Lymphoma; Contiguous Stage II Grade 2 Follicular Lymphoma; Contiguous Stage II Grade 3 Follicular Lymphoma; Contiguous Stage II Mantle Cell Lymphoma; Contiguous Stage II Marginal Zone Lymphoma; Contiguous Stage II Small Lymphocytic Lymphoma; Cutaneous B-cell Non-Hodgkin Lymphoma; Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue; Intraocular Lymphoma; Nodal Marginal Zone B-cell Lymphoma; Noncontiguous Stage II Adult Burkitt Lymphoma; Noncontiguous Stage II Adult Diffuse Large Cell Lymphoma; Noncontiguous Stage II Adult Diffuse Mixed Cell Lymphoma; Noncontiguous Stage II Adult Diffuse Small Cleaved Cell Lymphoma; Noncontiguous Stage II Adult Immunoblastic Large Cell Lymphoma; Noncontiguous Stage II Adult Lymphoblastic Lymphoma; Noncontiguous Stage II Grade 1 Follicular Lymphoma; Noncontiguous Stage II Grade 2 Follicular Lymphoma; Noncontiguous Stage II Grade 3 Follicular Lymphoma; Noncontiguous Stage II Mantle Cell Lymphoma; Noncontiguous Stage II Marginal Zone Lymphoma; Noncontiguous Stage II Small Lymphocytic Lymphoma; Primary Central Nervous System Non-Hodgkin Lymphoma; Recurrent Adult Burkitt Lymphoma; Recurrent Adult Diffuse Large Cell Lymphoma; Recurrent Adult Diffuse Mixed Cell Lymphoma; Recurrent Adult Diffuse Small Cleaved Cell Lymphoma; Recurrent Adult Grade III Lymphomatoid Granulomatosis; Recurrent Adult Immunoblastic Large Cell Lymphoma; Recurrent Adult Lymphoblastic Lymphoma; Recurrent Grade 1 Follicular Lymphoma; Recurrent Grade 2 Follicular Lymphoma; Recurrent Grade 3 Follicular Lymphoma; Recurrent Mantle Cell Lymphoma; Recurrent Marginal Zone Lymphoma; Recurrent Small Lymphocytic Lymphoma; Splenic Marginal Zone Lymphoma; Stage I Adult Burkitt Lymphoma; Stage I Adult Diffuse Large Cell Lymphoma; Stage I Adult Diffuse Mixed Cell Lymphoma; Stage I Adult Diffuse Small Cleaved Cell Lymphoma; Stage I Adult Immunoblastic Large Cell Lymphoma; Stage I Adult Lymphoblastic Lymphoma; Stage I Grade 1 Follicular Lymphoma; Stage I Grade 2 Follicular Lymphoma; Stage I Grade 3 Follicular Lymphoma; Stage I Mantle Cell Lymphoma; Stage I Marginal Zone Lymphoma; Stage I Small Lymphocytic Lymphoma; Stage III Adult Burkitt Lymphoma; Stage III Adult Diffuse Large Cell Lymphoma; Stage III Adult Diffuse Mixed Cell Lymphoma; Stage III Adult Diffuse Small Cleaved Cell Lymphoma; Stage III Adult Immunoblastic Large Cell Lymphoma; Stage III Adult Lymphoblastic Lymphoma; Stage III Grade 1 Follicular Lymphoma; Stage III Grade 2 Follicular Lymphoma; Stage III Grade 3 Follicular Lymphoma; Stage III Mantle Cell Lymphoma; Stage III Marginal Zone Lymphoma; Stage III Small Lymphocytic Lymphoma; Stage IV Adult Burkitt Lymphoma; Stage IV Adult Diffuse Large Cell Lymphoma; Stage IV Adult Diffuse Mixed Cell Lymphoma; Stage IV Adult Diffuse Small Cleaved Cell Lymphoma; Stage IV Adult Immunoblastic Large Cell Lymphoma; Stage IV Adult Lymphoblastic Lymphoma; Stage IV Grade 1 Follicular Lymphoma; Stage IV Grade 2 Follicular Lymphoma; Stage IV Grade 3 Follicular Lymphoma; Stage IV Mantle Cell Lymphoma; Stage IV Marginal Zone Lymphoma; Stage IV Small Lymphocytic Lymphoma; Waldenstrom Macroglobulinemia
Interventions: Biological: filgrastim; Drug: plerixafor; Biological: rituximab; Drug: ifosfamide; Drug: carboplatin; Drug: etoposide; Procedure: leukapheresis
Sponsor: Fred Hutchinson Cancer Research Center
Recruiting - verified August 2010
Polyethylene Glycol (PEG) Versus Sennosides Study in Opioid-Induced Constipation in Cancer Patients

Posted: March 17th, 2010, 9:00am CDT

Conditions: Constipation; Cancer
Interventions: Drug: PEG then Senna; Drug: Senna then PEG
Sponsor: British Columbia Cancer Agency
Recruiting - verified August 2010
$Permalink for 'Gamma-Secretase Inhibitor RO4929097 in Treating Young Patients With Relapsed or Refractory Solid Tumors, CNS Tumors, Lymphoma, or T-Cell Leukemia'$
Gamma-Secretase Inhibitor RO4929097 in Treating Young Patients With Relapsed or Refractory Solid Tumors, CNS Tumors, Lymphoma, or T-Cell Leukemia

Posted: March 16th, 2010, 9:00am CDT

Conditions: Brain and Central Nervous System Tumors; Leukemia; Lymphoma; Unspecified Childhood Solid Tumor, Protocol Specific
Interventions: Drug: dexamethasone; Drug: gamma-secretase inhibitor RO4929097; Other: laboratory biomarker analysis; Other: pharmacological study
Sponsors: Children's Oncology Group; National Cancer Institute (NCI)
Recruiting - verified August 2010
Adenosine 2A Agonist Lexiscan in Children and Adults With Sickle Cell Disease

Posted: March 10th, 2010, 9:00am CST

Condition: Sickle Cell Disease
Intervention: Drug: Lexiscan
Sponsors: Dana-Farber Cancer Institute; Brigham and Women's Hospital; Children's Hospital Boston; Washington University School of Medicine; LaJolla Institute for Allergy and Immunology; National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified July 2010
Study of Induction Treatment With Velcade and Dexamethasone for Previously Untreated Patients With Multiple Myeloma and Renal Failure

Posted: March 7th, 2010, 9:00am CST

Condition: Multiple Myeloma
Intervention: Drug: velcade
Sponsor: PETHEMA Foundation
Recruiting - verified July 2010
Phase 3 Study Comparing Carfilzomib, Lenalidomide, and Dexamethasone (CRd) vs Lenalidomide and Dexamethasone (Rd) in Subjects With Relapsed Multiple Myeloma

Posted: March 2nd, 2010, 9:00am CST

Condition: Relapsed Multiple Myeloma
Interventions: Drug: Dexamethasone; Drug: Lenalidomide; Drug: Carfilzomib
Sponsor: Onyx Therapeutics, Inc.
Recruiting - verified July 2010
$Permalink for 'Vorinostat and Temozolomide in Treating Young Patients With Relapsed or Refractory Primary Brain Tumors or Spinal Cord Tumors'$
Vorinostat and Temozolomide in Treating Young Patients With Relapsed or Refractory Primary Brain Tumors or Spinal Cord Tumors

Posted: February 25th, 2010, 9:00am CST

Conditions: Brain and Central Nervous System Tumors; Malignant Paraganglioma
Interventions: Drug: temozolomide; Drug: vorinostat; Genetic: DNA methylation analysis; Genetic: western blotting; Other: laboratory biomarker analysis; Other: pharmacological study
Sponsors: Children's Oncology Group; National Cancer Institute (NCI)
Recruiting - verified August 2010
Efficacy of Two Antiemetic Regimens in Patients Receiving Radiotherapy and Concomitant Weekly Cisplatin

Posted: February 23rd, 2010, 9:00am CST

Conditions: Nausea; Vomiting; Genital Neoplasms, Female
Intervention: Drug: Fosaprepitant dimeglumine
Sponsors: Odense University Hospital; Helsinn Healthcare SA
Recruiting - verified August 2010
Corticosteroids With Placebo Versus Corticosteroids With Propranolol Treatment of Infantile Hemangiomas (IH)

Posted: February 22nd, 2010, 9:00am CST

Condition: Hemangioma
Interventions: Drug: Prednisolone (Corticosteroid); Drug: Propanolol; Drug: Placebo
Sponsor: Seattle Children's Hospital
Recruiting - verified August 2010
Bortezomib, Cyclophosphamide, and Dexamethasone in Treating Patients With Primary Systemic Light Chain Amyloidosis

Posted: February 17th, 2010, 9:00am CST

Condition: Primary Systemic Amyloidosis
Interventions: Drug: bortezomib; Drug: cyclophosphamide; Drug: dexamethasone
Sponsor: Mayo Clinic
Recruiting - verified August 2010
Effect of Ridaforolimus on the Pharmacokinetics of Midazolam (8669-044)

Posted: February 17th, 2010, 9:00am CST

Condition: Advanced Cancer
Interventions: Drug: ridaforolimus; Drug: midazolam
Sponsors: Merck; Ariad Pharmaceuticals
Recruiting - verified August 2010
Standard Dose Bevacizumab Versus Low Dose Bevacizumab Plus Lomustine (CCNU) for Recurrent Glioblastoma Multiforme (GBM)

Posted: February 10th, 2010, 9:00am CST

Conditions: Brain Cancer; Glioblastoma
Interventions: Drug: Standard Dose Bevacizumab; Drug: Low Dose Bevacizumab; Drug: Lomustine
Sponsor: M.D. Anderson Cancer Center
Recruiting - verified August 2010
Temozolomide and Radiation Therapy With or Without Cediranib Maleate in Treating Patients With Newly Diagnosed Glioblastoma

Posted: February 3rd, 2010, 9:00am CST

Condition: Brain and Central Nervous System Tumors
Interventions: Drug: cediranib maleate; Drug: temozolomide; Other: placebo; Radiation: 3-dimensional conformal radiation therapy; Radiation: intensity-modulated radiation therapy
Sponsors: Radiation Therapy Oncology Group; National Cancer Institute (NCI)
Recruiting - verified August 2010
A Study of Xeloda (Capecitabine) in Breast Cancer Patients With Central Nervous System (CNS) Progression

Posted: January 15th, 2010, 9:00am CST

Condition: Breast Cancer
Intervention: Drug: capecitabine [Xeloda]
Sponsor: Hoffmann-La Roche
Recruiting - verified August 2010
Cilengitide and Sunitinib Malate in Treating Patients With Advanced Solid Tumors or Glioblastoma Multiforme

Posted: January 12th, 2010, 9:00am CST

Conditions: Brain and Central Nervous System Tumors; Unspecified Adult Solid Tumor, Protocol Specific
Interventions: Drug: cilengitide; Other: clinical observation
Sponsors: University of Chicago; National Cancer Institute (NCI)
Recruiting - verified August 2010

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Rare Cancer News & Clinical Trials » Trial - CNS Tumor

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