Rare Cancer News & Clinical Trials » Trial

Pharmacokinetics of Oral Antiplatelet Agents After Distal Gastrectomy

Posted: September 16th, 2022, 2:00pm GMT

Conditions: Stomach Neoplasm; Cardiovascular Diseases; Cerebrovascular Disease
Intervention: Diagnostic Test: Platelet function testing
Sponsor: Kyungpook National University Chilgok Hospital
Recruiting

Safety of Navoximod and NLG802 With Stereotactic Body Radiotherapy (SBRT) Treatment of Advanced Solid Tumors

Posted: July 21st, 2022, 2:00pm GMT

Condition: Advanced Solid Tumors
Interventions: Radiation: Stereotactic Body Radiotherapy (SBRT); Drug: navoximod; Drug: NLG802 (indoximod Prodrug)
Sponsors: Luke, Jason, MD; Lumos Pharma
Not yet recruiting

Permalink for 'An Open-label, Phase 2trial of Sotorasib in KRAS G12C-mutant Non-small-cell Lung Cancer(NSCLC) Patients and a Translational Study to Find Acquired Resistance Mechanism to Sotorasib'

An Open-label, Phase 2trial of Sotorasib in KRAS G12C-mutant Non-small-cell Lung Cancer(NSCLC) Patients and a Translational Study to Find Acquired Resistance Mechanism to Sotorasib

Posted: July 11th, 2022, 2:00pm GMT

Condition: Non Small Cell Lung Cancer
Intervention: Drug: sotorasib
Sponsor: Yonsei University
Not yet recruiting

Postmortem Evaluation of Adrenal and Other Endocrine Tumors in Patients With Sudden Death

Posted: July 7th, 2022, 2:00pm GMT

Conditions: Primary Aldosteronism; Adrenal Cushing Syndrome; Pheochromocytoma; Endocrine Neoplasia
Interventions: Diagnostic Test: Adrenal aldosterone synthase (CYP11B2) staining; Diagnostic Test: Adrenal cortisol synthase (CYP11B1) staining; Diagnostic Test: Histopathological analysis
Sponsors: Helsinki University Central Hospital; Finnish Institute for Health and Welfare; University of Helsinki; Tampere University Hospital; Tampere University
Recruiting

SPI-62 as a Treatment for Hypercortisolism Related to a Benign Adrenal Tumor

Posted: June 29th, 2022, 2:00pm GMT

Conditions: Autonomous Cortisol Secretion (ACS); ACTH-Independent Cushing Syndrome; ACTH-Independent Adrenal Cushing Syndrome, Somatic
Interventions: Drug: SPI-62 dose1; Drug: SPI-62 dose 2; Drug: SPI-62 dose 3; Drug: SPI-62 dose 4; Drug: Placebo
Sponsor: Sparrow Pharmaceuticals
Recruiting

Endoscopic Ultrasound-guided Radiofrequency Ablation in Primary Aldosteronism

Posted: May 10th, 2022, 2:00pm GMT

Conditions: Primary Aldosteronism; Aldosterone-Producing Adenoma
Interventions: Procedure: EUS-RFA of left adrenal gland; Procedure: adrenalectomy
Sponsor: Haukeland University Hospital
Recruiting

International REgistry of COnservative or Radical Treatment of Localized Kidney Tumors

Posted: May 6th, 2022, 2:00pm GMT

Condition: Kidney Cancer
Interventions: Procedure: Partial Nephrectomy (PN); Procedure: Radical Nephrectomy (RN); Procedure: Ablation therapy (AT); Diagnostic Test: Active Surveillance (AS)
Sponsors: Azienda Ospedaliero-Universitaria Careggi; Società Italiana di Urologia (SIU); Italian Group for Advanced Laparo-Endoscopic and Robotic Urologic Surgery (AGILE)
Recruiting

"The Efficacy of Exparel Versus a Multidrug Cocktail in Soft Tissue Tumors"

Posted: May 2nd, 2022, 2:00pm GMT

Conditions: Musculoskeletal Diseases; Soft Tissue Mass
Interventions: Drug: Exparel Injectable Product; Drug: Multi-Drug Cocktail (Ropivicaine, Epinephrine, Ketolorac, Clonidine)
Sponsor: Morristown Medical Center
Recruiting

Tranexamic Acid During Colonic Endoscopic Resection Procedures

Posted: April 26th, 2022, 2:00pm GMT

Condition: Colon Neoplasm
Interventions: Drug: Tranexamic acid; Drug: Standard
Sponsor: Assaf-Harofeh Medical Center
Recruiting

Survivorship Plan HEalth REcord (SPHERE) Implementation Trial

Posted: April 26th, 2022, 2:00pm GMT

Condition: Cancer
Intervention: Behavioral: Survivorship Care Plan-Personal Health Record (SCP-PHR)
Sponsors: Indiana University; National Cancer Institute (NCI)
Not yet recruiting

Transgender Observational Performance

Posted: April 20th, 2022, 2:00pm GMT

Condition: Transgender Persons
Intervention: Other: Aerobic exercise test.
Sponsor: Instituto Brasileiro de Controle do Cancer
Not yet recruiting

Complication in Laparoscopic Renal and Adrenal Surgery (CLARAS)

Posted: April 11th, 2022, 2:00pm GMT

Conditions: Adrenal Disease; Renal Cancer; Surgery--Complications
Intervention: Procedure: laparoscopic surgery for renal and adrenal diseases
Sponsors: University of Palermo; Fundacio Puigvert
Recruiting

TAP vs QL for Postoperative Analgesia After DIEP Free Flap Breast Reconstruction

Posted: March 29th, 2022, 2:00pm GMT

Condition: Breast Cancer
Interventions: Procedure: TAP block; Procedure: QL Block
Sponsor: Ottawa Hospital Research Institute
Not yet recruiting

Bacteriostatic Saline as a Local Anesthetic in Minor Eyelid Procedures

Posted: March 24th, 2022, 2:00pm GMT

Conditions: Eyelid Tumor; Eyelid Bump; Eyelid Deformity; Eyelid Abscess; Eyelid Boil; Eyelid Papilloma; Anesthesia, Local; Ophthalmology
Interventions: Drug: 0.9% Bacteriostatic Local Anesthetic Injection; Drug: 1% Lidocaine with 1:100,000 epinephrine Local Anesthetic Injection; Procedure: Eyelid Lesion Removal
Sponsor: University of California, San Francisco
Not yet recruiting

A Multilevel Approach for Improvement in Screening of Colorectal Cancer in Rural Communities, The Screen to Save Trial

Posted: March 23rd, 2022, 2:00pm GMT

Condition: Colorectal Carcinoma
Interventions: Other: Educational Intervention; Other: Fecal Immunochemical Test; Other: Questionnaire Administration
Sponsor: Fred Hutchinson Cancer Center
Not yet recruiting

Lazertinib for Patients With NSCLC Harboring Uncommon EGFR Mutations

Posted: March 14th, 2022, 2:00pm GMT

Condition: NSCLC
Intervention: Drug: Lazertinib
Sponsor: Yonsei University
Not yet recruiting

Learning Curve for Gastric Endoscopic Submucosal Dissection

Posted: March 3rd, 2022, 3:00pm GMT

Conditions: Endoscopic Submucosal Dissection; Gastric Neoplasm
Intervention: Procedure: Endoscopic submucosal dissection
Sponsor: Soonchunhyang University Hospital
Recruiting

Efficacy of Ipsilateral High Thoracic Ultrasound-guided Erector Spinae Plane Block in Thoracic Cancer Surgeries

Posted: February 14th, 2022, 3:00pm GMT

Conditions: Thoracotomy; Erector Spinae Plane Block; Thoracic Cancer; Shoulder Pain
Interventions: Procedure: Thoracic Epidural Analgesia (TEA) group; Procedure: Thoracic Epidural Analgesia and Erector Spinae Plane Block (ESPB) group
Sponsor: Cairo University
Not yet recruiting

Permalink for 'A Study Evaluating the Safety and Efficacy of ENV-101 (Taladegib) in Patients With Advanced Solid Tumors Harboring PTCH1 Loss of Function Mutations'

A Study Evaluating the Safety and Efficacy of ENV-101 (Taladegib) in Patients With Advanced Solid Tumors Harboring PTCH1 Loss of Function Mutations

Posted: January 20th, 2022, 3:00pm GMT

Condition: Solid Tumors With PTCH1 Loss-of-function Mutations
Intervention: Drug: ENV-101 (taladegib)
Sponsor: Endeavor Biomedicines, Inc.
Recruiting

Stereotactic Ablative Radiotherapy for Oligometastatic Hepatocellular Carcinoma

Posted: December 30th, 2021, 3:00pm GMT

Condition: Oligometastasis Hepatocellular Carcinoma
Intervention: Radiation: Radiation: Stereotactic body radiotherapy (SBRT)
Sponsor: Yonsei University
Recruiting

Real-time Ultrasound Guidance for Thoracic Epidural Blocks

Posted: December 21st, 2021, 3:00pm GMT

Conditions: Analgesia; Thoracic Tumors; Abdomen Tumors; Rib Fractures
Intervention: Procedure: Real-time ultrasound guidance for thoracic epidural catheter placement.
Sponsor: University of Chile
Not yet recruiting

Permalink for 'Comparison of Chronocort Versus Standard Hydrocortisone Replacement Therapy in Participants Aged 16 Years and Over With Congenital Adrenal Hyperplasia'

Comparison of Chronocort Versus Standard Hydrocortisone Replacement Therapy in Participants Aged 16 Years and Over With Congenital Adrenal Hyperplasia

Posted: October 1st, 2021, 2:00pm GMT

Condition: Congenital Adrenal Hyperplasia
Interventions: Drug: Chronocort; Drug: Cortef
Sponsor: Diurnal Limited
Recruiting

Feasibility of 2 Interventions to Reduce Fatigue in Patients With Chemotherapy for Metastatic Colorectal Cancer

Posted: August 10th, 2021, 2:00pm GMT

Condition: Colorectal Cancer Metastatic
Interventions: Behavioral: Hypnosis; Behavioral: CBT
Sponsor: Institut du Cancer de Montpellier - Val d'Aurelle
Recruiting

Stereotactic MRI-guided Adaptive Radiation Therapy (SMART) in One Fraction

Posted: June 25th, 2021, 2:00pm GMT

Condition: Metastatic Carcinoma
Intervention: Radiation: Stereotactic ablative body radiation therapy
Sponsors: Baptist Health South Florida; Viewray Inc.
Recruiting

B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR)

Posted: May 21st, 2021, 2:00pm GMT

Conditions: Pediatric Solid Tumor; Osteosarcoma; Rhabdomyosarcoma; Neuroblastoma; Ewing Sarcoma; Wilms Tumor; Adrenocortical Cancer; Desmoplastic Small Round Cell Tumor; Germ Cell Cancer; Rhabdoid Tumor; Clear Cell Sarcoma; Hepatoblastoma; Melanoma; Carcinoma; Malignant Peripheral Nerve Sheath Tumors; Soft Tissue Sarcoma
Interventions: Drug: Fludarabine; Drug: Cyclophosphamide; Drug: MESNA; Drug: B7-H3 CAR T cells
Sponsor: St. Jude Children's Research Hospital
Recruiting

Adrenomedullin in Context With Pulmonary Embolism

Posted: May 6th, 2021, 2:00pm GMT

Condition: Pulmonary Embolism
Intervention: Diagnostic Test: blood samples
Sponsor: University of Pecs
Recruiting

The Efficacy and Safety of Anlotinib in Patients With Metastatic Pheochromocytoma or Paraganglioma

Posted: April 27th, 2021, 2:00pm GMT

Conditions: Malignant Adrenal Gland Pheochromocytoma; Malignant Paraganglioma; Pheochromocytoma, Metastatic; Paraganglioma, Malignant; Paraganglioma, Extra-Adrenal
Intervention: Drug: anlotinib hydrochloride
Sponsor: Peking Union Medical College Hospital
Recruiting

Evaluation of New Diagnostic Indicator of Subclinical Hypercortisolism

Posted: April 6th, 2021, 2:00pm GMT

Conditions: Adrenal Incidentaloma; Subclinical Hypercortisolism
Intervention: Diagnostic Test: experimental group
Sponsor: The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Recruiting

Permalink for 'Anti-CTLA4-NF mAb (BMS986218), Nivolumab, and Stereotactic Body Radiation Therapy for the Treatment of Metastatic Solid Malignancies'

Anti-CTLA4-NF mAb (BMS986218), Nivolumab, and Stereotactic Body Radiation Therapy for the Treatment of Metastatic Solid Malignancies

Posted: March 5th, 2021, 3:00pm GMT

Conditions: Advanced Lung Carcinoma; Advanced Malignant Solid Neoplasm; Malignant Adrenal Gland Neoplasm; Metastatic Liver Carcinoma; Metastatic Lung Carcinoma; Metastatic Malignant Solid Neoplasm; Stage III Liver Cancer; Stage III Lung Cancer AJCC v8; Stage IIIA Lung Cancer AJCC v8; Stage IIIB Lung Cancer AJCC v8; Stage IIIC Lung Cancer AJCC v8; Stage IV Liver Cancer; Stage IV Lung Cancer AJCC v8; Stage IVA Liver Cancer; Stage IVA Lung Cancer AJCC v8; Stage IVB Liver Cancer; Stage IVB Lung Cancer AJCC v8
Interventions: Biological: Anti-CTLA4 Monoclonal Antibody BMS-986218; Biological: Nivolumab; Radiation: Stereotactic Body Radiation Therapy
Sponsor: M.D. Anderson Cancer Center
Recruiting

Permalink for 'Iberdomide Alone or in Combination With Dexamethasone for the Treatment of Intermediate- or High-Risk Smoldering Multiple Myeloma'

Iberdomide Alone or in Combination With Dexamethasone for the Treatment of Intermediate- or High-Risk Smoldering Multiple Myeloma

Posted: March 1st, 2021, 3:00pm GMT

Condition: Smoldering Plasma Cell Myeloma
Interventions: Drug: Dexamethasone; Drug: Iberdomide Hydrochloride; Other: Quality-of-Life Assessment
Sponsors: Emory University; Bristol-Myers Squibb; National Cancer Institute (NCI)
Recruiting

Developing a Virtual Stress Management Intervention for Spousal/Partnered Caregivers of Solid Tumor Cancer Patients.

Posted: February 5th, 2021, 3:00pm GMT

Conditions: Breast Cancer; Lung Cancer; Colon Cancer; Solid Tumor, Adult
Interventions: Behavioral: PEPRR; Behavioral: Pep-Pal
Sponsors: University of Colorado, Denver; National Cancer Institute (NCI)
Recruiting

Intraoperative Norepinephrine Versus Fresh Frozen Plasma in Patients Undergoing HIPEC to Reduce Renal Insult

Posted: December 24th, 2020, 3:00pm GMT

Condition: Anesthesia
Interventions: Drug: Norepinephrine; Biological: Fresh frozen plasma
Sponsor: National Cancer Institute, Egypt
Recruiting

RCT Comparing ESPB Solutions in Breast Surgery

Posted: October 27th, 2020, 2:00pm GMT

Condition: Breast Cancer
Interventions: Drug: Liposomal bupivacaine; Drug: Bupivacaine, epinephrine, dexamethasone, and clonidine
Sponsor: Tufts Medical Center
Recruiting

Endoscopic Mucosal Resection Versus Endoscopic Submucosal Dissection for Colorectal Laterally Spreading Lesions.

Posted: October 20th, 2020, 2:00pm GMT

Condition: Neoplasms, Colorectal
Interventions: Procedure: Endoscopic mucosal resection (EMR); Procedure: Endoscopic submucosal dissection (ESD)
Sponsors: José Carlos Marín Gabriel; Spanish Society of Digestive Endoscopy
Recruiting

Prospective Exploratory Study of FAPi PET/CT With Histopathology Validation in Patients With Various Cancers

Posted: July 7th, 2020, 2:00pm GMT

Conditions: Bladder Carcinoma; Cervical Carcinoma; Cholangiocarcinoma; Hematopoietic and Lymphoid Cell Neoplasm; Hepatocellular Carcinoma; Malignant Adrenal Gland Neoplasm; Malignant Brain Neoplasm; Malignant Pleural Neoplasm; Malignant Skin Neoplasm; Malignant Solid Neoplasm; Malignant Testicular Neoplasm; Malignant Thymus Neoplasm; Neuroendocrine Neoplasm; Thyroid Gland Carcinoma; Urothelial Carcinoma
Interventions: Procedure: Computed Tomography; Drug: Gallium Ga 68 FAPi-46; Procedure: Positron Emission Tomography
Sponsor: Jonsson Comprehensive Cancer Center
Recruiting

SpotCheck: Comparison of Enhanced Telemedicine Versus In-person Evaluation for the Diagnosis of Skin Cancer

Posted: June 2nd, 2020, 2:00pm GMT

Condition: Skin Cancer
Interventions: Device: Nevisense 3.0; Device: Dermlite Cam; Procedure: Skin biopsy
Sponsor: NYU Langone Health
Recruiting

Stereotactic Magnetic Resonance Guided Radiation Therapy

Posted: October 3rd, 2019, 2:00pm GMT

Conditions: Pancreas Cancer; Lung Cancer; Renal Cancer; Adrenal Metastases; Prostate Cancer; Liver Metastases; Oligoprogressive Nodal Metastases; Metachronous Nodal Metastases; Synchronous Nodal Metastases; Mesothelioma; Spine Metastases; Brain Metastases; Borderline Resectable Pancreatic Carcinoma
Intervention: Radiation: MR-guided Linac
Sponsor: Dana-Farber Cancer Institute
Recruiting

Dose-Escalation and Efficacy Study of LAE001/Prednisone Plus Afuresertib Patients With m-CRPC

Posted: August 19th, 2019, 2:00pm GMT

Condition: Metastatic Castration-resistant Prostate Cancer
Intervention: Drug: Phase I and Phase II: LAE001/prednisone + afuresertib
Sponsor: Laekna Limited
Recruiting

RCT of Gastric ESD With or Without Epineprhine Added Solution

Posted: July 25th, 2019, 2:00pm GMT

Conditions: Gastric Neoplasm; Early Gastric Cancer
Interventions: Procedure: Endoscopic submucosal dissection; Drug: Epinephrine
Sponsors: Chinese University of Hong Kong; Osaka International Cancer Institute; Shizuoka Cancer Center; Fukuoka University; Changi General Hospital; Kyoto 2nd Red Cross Hospital; Ishikawa Prefectural Central Hospital; Kosin University Gospel Hospital; Machida General Hospital; Nara City Hospital; Wakayama Red Cross Hospital; JCHO Osaka Hospital; Sapporo Kinentou hospital; Japan Community Healthcare Organization Osaka Hospital
Recruiting

Paravertebral Block Versus Thoracic Epidural Analgesia

Posted: July 19th, 2019, 2:00pm GMT

Conditions: Lung Cancer; Postoperative Pain
Interventions: Drug: Thoracic epidural; Drug: Paravertebral block
Sponsor: St. Olavs Hospital
Recruiting

Cryoablation of Bone Metastases From Endocrine Tumors

Posted: June 14th, 2019, 2:00pm GMT

Conditions: Neoplasm Metastasis; Thyroid Neoplasm; Pheochromocytoma; Adrenal Neoplasm; Neuroendocrine Tumors; Bone Metastases
Intervention: Device: cryoablation
Sponsors: Instituto do Cancer do Estado de São Paulo; University of Sao Paulo General Hospital
Recruiting

Stereotactic Ablative Radiotherapy for Comprehensive Treatment of Oligometastatic (1-3 Metastases) Cancer

Posted: March 5th, 2019, 3:00pm GMT

Condition: Metastatic Tumors
Interventions: Radiation: palliative radiotherapy; Radiation: Stereotactic ablative radiotherapy
Sponsors: British Columbia Cancer Agency; London Regional Cancer Program, Canada; The Alfred; Beacon Hospital, Ireland; Cancer Trials Ireland
Recruiting

Long-Term Follow-Up of Survivors of Pediatric Cushing Disease

Posted: February 6th, 2019, 3:00pm GMT

Condition: Cushing Disease
Intervention:
Sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Recruiting

Conventional ADT w/ or w/Out Abiraterone Acetate + Prednisone and Apalutamide Following a Detectable PSA After Radiation and ADT

Posted: December 19th, 2018, 3:00pm GMT

Condition: Prostate Cancer
Interventions: Drug: Prednisone; Drug: Apalutamide; Drug: Abiraterone Acetate; Drug: LHRH Agonist or Antagonist
Sponsors: Dana-Farber Cancer Institute; Janssen Scientific Affairs, LLC
Recruiting

Cabozantinib in Advanced Adrenocortical Carcinoma

Posted: August 2nd, 2018, 2:00pm GMT

Condition: Adrenocortical Carcinoma
Intervention: Drug: Cabozantinib-s-malate
Sponsor: Wuerzburg University Hospital
Recruiting

Permalink for 'Mitotane With or Without Cisplatin and Etoposide After Surgery in Treating Patients With Stage I-III Adrenocortical Cancer With High Risk of Recurrence'

Mitotane With or Without Cisplatin and Etoposide After Surgery in Treating Patients With Stage I-III Adrenocortical Cancer With High Risk of Recurrence

Posted: July 11th, 2018, 2:00pm GMT

Conditions: ENSAT Stage I Adrenal Cortex Carcinoma; ENSAT Stage II Adrenal Cortex Carcinoma; ENSAT Stage III Adrenal Cortex Carcinoma
Interventions: Drug: Cisplatin; Drug: Etoposide; Drug: Mitotane; Other: Quality-of-Life Assessment
Sponsors: M.D. Anderson Cancer Center; National Cancer Institute (NCI)
Recruiting

Neoplastic Barrett Esophagus: Endoscopic Piecemeal vs. En Bloc Resection

Posted: February 9th, 2018, 3:00pm GMT

Conditions: Barrett Esophagus; Barrett Adenocarcinoma; Esophagus Neoplasm
Interventions: Procedure: Endoscopic mucosal resection; Procedure: Endoscopic submucosal dissection
Sponsor: Universitätsklinikum Hamburg-Eppendorf
Recruiting

Nivolumab Combined With Ipilimumab for Patients With Advanced Rare Genitourinary Tumors

Posted: November 7th, 2017, 3:00pm GMT

Conditions: Genitourinary Cancer; Adrenocortical Carcinoma; Non-urothelial Bladder; Non-urothelial Upper Tract; Penile Cancer; Non-adenocarcinoma Prostate Cancer; Refractory Germ-cell; High Grade Neuroendocrine Carcinoma/Small Cell Carcinoma
Interventions: Drug: Ipilimumab; Drug: Nivolumab
Sponsors: Dana-Farber Cancer Institute; Bristol-Myers Squibb
Recruiting

Feasibility and Safety of IMP321 for Advanced Stage Solid Tumors

Posted: August 17th, 2017, 2:00pm GMT

Conditions: Solid Tumors; Peritoneal Carcinomatosis
Interventions: Drug: IMP321; Drug: Avelumab
Sponsor: Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest
Recruiting

Familial Investigations of Childhood Cancer Predisposition

Posted: February 10th, 2017, 3:00pm GMT

Conditions: Acute Leukemia; Adenomatous Polyposis; Adrenocortical Carcinoma; AML; BAP1 Tumor Predisposition Syndrome; Carney Complex; Choroid Plexus Carcinoma; Constitutional Mismatch Repair Deficiency Syndrome; Diamond-Blackfan Anemia; DICER1 Syndrome; Dyskeratosis Congenita; Emberger Syndrome; Familial Acute Myeloid Leukemia; Familial Adenomatous Polyposis; Fanconi Anemia; Familial Cancer; Familial Wilms Tumor; Familial Neuroblastoma; GIST; Hereditary Breast and Ovarian Cancer; Hereditary Paraganglioma-Pheochromocytoma Syndrome; Hodgkin Lymphoma; Juvenile Polyposis; Li-Fraumeni Syndrome; Lynch Syndrome; MDS; Melanoma Syndrome; Multiple Endocrine Neoplasia Type 1; Multiple Endocrine Neoplasia Type 2; Neuroblastoma; Neurofibromatosis Type 1; Neurofibromatosis Type II; Nevoid Basal Cell Carcinoma Syndrome; Non Hodgkin Lymphoma; Noonan Syndrome and Other Rasopathy; Overgrowth Syndromes; Pancreatic Cancer; Peutz-Jeghers Syndrome; Pheochromocytoma/Paraganglioma; PTEN Hamartoma Tumor Syndrome; Retinoblastoma; Rhabdoid Tumor Predisposition Syndrome; Rhabdomyosarcoma; Rothmund-Thomson Syndrome; Tuberous Sclerosis; Von Hippel-Lindau Disease
Intervention:
Sponsor: St. Jude Children's Research Hospital
Recruiting

Study of Biomarker-Based Treatment of Acute Myeloid Leukemia

Posted: January 9th, 2017, 3:00pm GMT

Condition: Previously Untreated Acute Myeloid Leukemia
Interventions: Biological: Samalizumab (BAML-16-001-S1); Biological: BI 836858 (BAML-16-001-S2); Other: Laboratory Biomarker Analysis; Drug: Daunorubicin (BAML-16-001-S1); Drug: Cytarabine (BAML-16-001-S1); Drug: Azacitidine (BAML-16-001-S2); Drug: AG-221 (BAML-16-001-S3); Drug: Azacitidine (BAML-16-001-S3); Drug: Entospletinib (BAML-16-001-S4); Drug: Azacitidine (BAML-16-001-S4); Drug: Entospletinib (BAML-16-001-S5); Drug: Decitabine (BAML-16-001-S5); Drug: Entospletinib (BAML-16-001-S6); Drug: Daunorubicin (BAML-16-001-S6); Drug: Cytarabine (BAML-16-001-S6); Drug: Pevonedistat (BAML-16-001-S9); Drug: Azacitidine (BAML-16-001-S9); Drug: AG-120 (BAML-16-001-S16); Drug: Azacitidine (BAML-16-001-S16); Drug: Gilteritinib (BAML-16-001-S8 Group 1); Drug: Decitabine (BAML-16-001-S8 Group 1); Drug: AZD5153 (BAML-16-001-S10); Drug: Venetoclax (BAML-16-001-S10); Drug: TP-0903 (BAML-16-001-S14); Drug: Decitabine (BAML-16-001-S14); Drug: Decitabine (BAML-16-001-S8 Group 2); Drug: Venetoclax (BAML-16-001-S8 Group 2); Drug: AZD5991 (BAML-16-001-S18); Drug: Azacitidine (BAML-16-001-S18); Drug: SNDX-5613 (BAML-16-001-S17); Drug: Azacitidine (BAML-16-001-S17); Drug: Venetoclax (BAML-16-001-S17)
Sponsor: Beat AML, LLC
Recruiting

A Clinical and Molecular Risk-Directed Therapy for Newly Diagnosed Medulloblastoma

Posted: June 17th, 2013, 2:00pm GMT

Condition: Medulloblastoma
Interventions: Radiation: Craniospinal Irradiation with boost to the primary tumor site; Drug: Cyclophosphamide; Drug: Cisplatin; Drug: Vincristine; Drug: Vismodegib; Drug: Pemetrexed; Drug: Gemcitabine; Other: Aerobic Training; Other: Neurocognitive Remediation
Sponsors: St. Jude Children's Research Hospital; Genentech, Inc.; National Cancer Institute (NCI)
Recruiting

International Pediatric Adrenocortical Tumor Registry

Posted: June 18th, 2008, 2:00pm GMT

Condition: Adrenocortical Tumor
Intervention:
Sponsor: St. Jude Children's Research Hospital
Recruiting

Molecular Characterization of Neuroblastic Tumor: Correlation With Clinical Outcome

Posted: January 8th, 2008, 3:00pm GMT

Condition: Neuroblastoma
Intervention: Other: Tumor and Marrow Markers
Sponsors: Memorial Sloan Kettering Cancer Center; Southern Illinois University; Spanish National Cancer Center; St. Jude Children's Research Hospital; Washington University School of Medicine; University of Texas; Weill Medical College of Cornell University
Recruiting

Evaluation of Side Effects of Mitotane

Posted: December 5th, 2007, 3:00pm GMT

Condition: Adrenocortical Carcinoma
Intervention:
Sponsor: University of Wuerzburg
Recruiting

Rare Cancer News & Clinical Trials » Trial - Adrenal Cancer

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