Rare Cancer News & Clinical Trials » Trial

Dose-Escalation and Efficacy Study of LAE001/Prednisone Plus Afuresertib Patients With m-CRPC

Posted: August 19th, 2019, 2:00pm GMT

Condition: Metastatic Castration-resistant Prostate Cancer
Intervention: Drug: Phase I and Phase II: LAE001/prednisone + afuresertib
Sponsor: Laekna Limited
Not yet recruiting

Acute Effect of modeRate-intensity aerOBIc Exercise on Colon Cancer Cell Growth

Posted: August 15th, 2019, 2:00pm GMT

Conditions: Colon Adenocarcinoma; Colon Cancer
Intervention: Other: Exercise assessment
Sponsors: Northumbria University; York St John University; Newcastle University
Not yet recruiting

Analgesic Effect of Adding Thoracic Paravertebral Nerve Blocks to Modified PEC Block in Breast Cancer Surgery

Posted: August 14th, 2019, 2:00pm GMT

Conditions: Breast Cancer Female; Pain, Postoperative
Interventions: Procedure: Thoracic paravertebral block under ultrasound guidance; Procedure: Intraoperative modified PEC block; Procedure: GA with ETT
Sponsor: Mahidol University
Recruiting

RCT of Gastric ESD With or Without Epineprhine Added Solution

Posted: July 25th, 2019, 2:00pm GMT

Conditions: Gastric Neoplasm; Early Gastric Cancer
Interventions: Procedure: Endoscopic submucosal dissection; Drug: Epinephrine
Sponsors: Chinese University of Hong Kong; Osaka International Cancer Institute; Shizuoka Cancer Center; Fukuoka University; Changi General Hospital; Kyoto 2nd Red Cross Hospital; Ishikawa Prefectural Central Hospital
Not yet recruiting

The Master Registry of Oncology Outcomes Associated With Testing and Treatment

Posted: July 22nd, 2019, 2:00pm GMT

Conditions: Adenocarcinoma; Adenocystic Carcinoma; Anal Cancer; Appendix Cancer; Brain Tumor; Glioblastoma; Astrocytoma; Bile Duct Cancer; Cholangiocarcinoma; Bladder Cancer; Bone Cancer; Synovial Sarcoma; Chondrosarcoma; Liposarcoma; Sarcoma, Kaposi; Sarcoma,Soft Tissue; Sarcoma; Osteosarcoma; CNS Cancer; Brain Stem Neoplasms; Breast Cancer; Cervical Cancer; Colorectal Cancer; Rectal Cancer; Colon Cancer; Esophageal Cancer; Esophagus Cancer; Cancer of Colon; Pancreatic Cancer; Cancer of Pancreas; Testis Cancer; Testicular Cancer; Ureter Cancer; Renal Cell Carcinoma; Kidney Cancer; Gestational Trophoblastic Tumor; Head and Neck Neoplasms; Parotid Tumor; Larynx Cancer; Tongue Cancer; Pharynx Cancer; Salivary Gland Cancer; Acute Myeloid Leukemia; Chronic Myeloid Leukemia; Acute Lymphoblastic Leukemia; Multiple Myeloma; Non Hodgkin Lymphoma; Carcinoid Tumor; Lung Cancer; Pulmonary Candidiasis; Neuroendocrine Tumors; Mesothelioma; Thyroid Cancer; Parathyroid Neoplasms; Adrenal Cancer; Small Bowel Cancer; Stomach Cancer; Liver Cancer; Hepatic Cancer; Melanoma; Skin Cancer; Unknown Primary Tumors; Uterine Cancer; Fallopian Tube Cancer; Ovarian Cancer; Prostate Cancer; Vaginal Cancer; Penile Cancer; Vulvar Cancer; Waldenstrom Macroglobulinemia; Cancer, Advanced; Thymus Cancer; Nasopharyngeal Carcinoma; Multiple Endocrine Neoplasia; Pheochromocytoma; Small Cell Carcinoma
Interventions: Diagnostic Test: Testing: Genome; Diagnostic Test: Testing: Transcriptome; Diagnostic Test: Testing: Proteome; Drug: Treatment: CAR-T
Sponsor: Taproot Health
Not yet recruiting

Paravertebral Block Versus Thoracic Epidural Analgesia

Posted: July 19th, 2019, 2:00pm GMT

Conditions: Lung Cancer; Postoperative Pain
Interventions: Drug: Thoracic epidural; Drug: Paravertebral block
Sponsor: St. Olavs Hospital
Recruiting

Preoperative Pectoral Nerve Block for Acute and Chronic Post-Operative Pain Following Mastectomy

Posted: July 15th, 2019, 2:00pm GMT

Conditions: Breast Cancer; Mastectomy; Anesthesia, Local; Narcotic Use
Interventions: Drug: PECs block with local anesthesia of bupivacaine with steroid; Other: Placebo PECs block with normal saline
Sponsor: University of Alabama at Birmingham
Not yet recruiting

Primary Aldosteronism and Surgically Curable Forms in Hypertension Patients Using 11C-Metomidate

Posted: June 19th, 2019, 2:00pm GMT

Conditions: Primary Aldosteronism; Primary Aldosteronism Due to Aldosterone Producing Adenoma
Intervention: Combination Product: 11C-Metomidate PET/CT Scan
Sponsors: Changi General Hospital; National University Health System, Singapore; Clinical Imaging Research Centre; Singapore General Hospital; Tan Tock Seng Hospital; Khoo Teck Puat Hospital; Ng Teng Fong General Hospital
Recruiting

Cryoablation of Bone Metastases From Endocrine Tumors

Posted: June 14th, 2019, 2:00pm GMT

Conditions: Neoplasm Metastasis; Thyroid Neoplasm; Pheochromocytoma; Adrenal Neoplasm; Neuroendocrine Tumors; Bone Metastases
Intervention: Device: cryoablation
Sponsors: Instituto do Cancer do Estado de São Paulo; University of Sao Paulo General Hospital
Recruiting

AKT Inhibitor, Ipatasertib, With Endocrine and CDK 4/6 Inhibitor for Patients With Metastatic Breast Cancer (TAKTIC)

Posted: May 22nd, 2019, 2:00pm GMT

Condition: Breast Cancer
Interventions: Drug: Ipatasertib; Drug: Fulvestrant; Drug: Aromatase Inhibitor; Drug: Palbociclib
Sponsors: Massachusetts General Hospital; Genentech, Inc.
Recruiting

Colorectal Metastasis Prevention International Trial 2

Posted: April 18th, 2019, 2:00pm GMT

Condition: Colorectal Neoplasms
Interventions: Drug: Propranolol and etodolac; Other: Placebo
Sponsors: Assaf-Harofeh Medical Center; Sheba Medical Center; Rabin Medical Center; Tel-Aviv Sourasky Medical Center; Rambam Health Care Campus; HaEmek Medical Center, Israel
Recruiting

Erector Spinae Plane Block Versus Intercostal for VATS

Posted: April 4th, 2019, 2:00pm GMT

Conditions: Lung Cancer; Lung Diseases
Interventions: Procedure: ESP block; Procedure: Intercostal block; Procedure: Sham ESP block; Procedure: Sham Intercostal block; Drug: Bupivacaine-epinephrine; Drug: Dexamethasone injection; Drug: Normal saline
Sponsor: McGill University Health Center
Recruiting

Permalink for 'The PIONEER Initiative: Precision Insights On N-of-1 Ex Vivo Effectiveness Research Based on Individual Tumor Ownership (Precision Oncology)'

The PIONEER Initiative: Precision Insights On N-of-1 Ex Vivo Effectiveness Research Based on Individual Tumor Ownership (Precision Oncology)

Posted: April 1st, 2019, 2:00pm GMT

Conditions: Cancer, All Types; Cancer of Liver; Cancer of Stomach; Cancer of Head and Neck; Cancer of Rectum; Cancer of Kidney; Cancer of Esophagus; Cancer of Colon; Cancer Skin; Cancer of Cervix; Cancer, Metastatic; Cancer of Larynx; Cancer of Neck; Cancer of Lung; Cancer of Brain and Nervous System; Cancer of Vulva, Disseminated; Cancer of Pancreas; Sarcoma; GIST; Small-cell Lung Cancer; Adenocarcinoma Lung; Cancer of Prostate; Cancer, Advanced; Adrenal Cancer; Testicular Cancer; Uterine Cancer; Bronchoalveolar Cell Lung Cancer; Cancer Unknown Primary; Glioblastoma Multiforme; Oligodendroglioma; Breast Cancer; Renal Cell Carcinoma; Hepatocellular Carcinoma; Cholangiocarcinoma; Squamous Cell Carcinoma; Transitional Cell Carcinoma; Cancer, Other; Cancer, Anal; Melanoma; Cancer, Bile Duct; Cancer, Bladder; Cancer Cords Vocal; Cancers Cell Neuroendocrine; Cancer Differentiated Poorly; Cancer, Anaplastic Thyroid
Intervention:
Sponsors: SpeciCare; Dana-Farber Cancer Institute; Kalispell Regional Medical Center; Georgia Institute of Technology; Ontario Institute for Cancer Research; SEngine Precision Medicine; Helomics
Recruiting

Comparing the Efficacy of Local Anesthetics in Mohs Surgery

Posted: March 12th, 2019, 2:00pm GMT

Conditions: Lidocaine; Bupivacaine; Mohs Surgery; Anesthetic
Interventions: Drug: Lidocaine; Drug: Bupivacaine; Drug: Lidocaine and Bupivacaine
Sponsors: Ottawa Hospital Research Institute; Richard J. MacKay Endowment Fund; Benefactor Life Members’ Research Grant; The Ottawa Hospital Division of Dermatology
Not yet recruiting

Stereotactic Ablative Radiotherapy for Comprehensive Treatment of Oligometastatic (1-3 Metastases) Cancer

Posted: March 5th, 2019, 3:00pm GMT

Condition: Metastatic Tumors
Interventions: Radiation: palliative radiotherapy; Radiation: Stereotactic ablative radiotherapy
Sponsors: British Columbia Cancer Agency; London Regional Cancer Program, Canada; Beatson Institute for Cancer Research, Scotland; The Alfred; Beacon Hospital, Ireland
Not yet recruiting

Perioperative Intervention to Reduce Metastatic Processes in Pancreatic Cancer Patients Undergoing Curative Surgery

Posted: February 12th, 2019, 3:00pm GMT

Condition: Pancreatic Neoplasms
Interventions: Drug: Propranolol and etodolac; Other: Placebo
Sponsors: Assaf-Harofeh Medical Center; Sheba Medical Center
Not yet recruiting

Analgesia of Erector Spinae Plane Block Versus Quadratus Lumborum Block

Posted: January 14th, 2019, 3:00pm GMT

Condition: Colorectal Cancer
Interventions: Other: Erector spinae plane block; Other: Quadratus lumborum block; Drug: Propofol; Drug: Fentanyl NCS; Drug: Atracurium Injectable Product; Other: Endotracheal intubation; Drug: Anesthesia Maintenance; Drug: Muscle Relaxation
Sponsor: Mansoura University
Not yet recruiting

A Study of ASP1951 in Subjects With Advanced Solid Tumors

Posted: January 10th, 2019, 3:00pm GMT

Condition: Advanced Solid Tumors
Intervention: Drug: ASP1951
Sponsor: Astellas Pharma Global Development, Inc.
Recruiting

Conventional ADT w/ or w/Out Abiraterone Acetate + Prednisone and Apalutamide Following a Detectable PSA After Radiation and ADT

Posted: December 18th, 2018, 3:00pm GMT

Condition: Prostate Cancer
Interventions: Drug: Prednisone; Drug: Apalutamide; Drug: Abiraterone Acetate; Drug: LHRH Agonist or Antagonist
Sponsors: Dana-Farber Cancer Institute; Janssen Scientific Affairs, LLC
Not yet recruiting

Adjuvant Endocrine Therapy in Early Stage Breast Cancer: Adherence and Clinical Outcome

Posted: December 3rd, 2018, 3:00pm GMT

Condition: Breast Neoplasm
Intervention:
Sponsors: St. Olavs Hospital; Norwegian University of Science and Technology
Not yet recruiting

Mid-point Transverse Process to Pleura Block for Breast Cancer Surgery: A Randomized Controlled Trial

Posted: October 19th, 2018, 2:00pm GMT

Conditions: Breast Cancer; Acute Pain; Anesthesia
Interventions: Procedure: PVB group; Procedure: MTP block group; Procedure: Control Group
Sponsor: Ottawa Hospital Research Institute
Not yet recruiting

Functional MRI Study Reconstructed Breasts

Posted: October 11th, 2018, 2:00pm GMT

Condition: Breast Cancer
Intervention: Device: MRI scan
Sponsor: Maastricht University Medical Center
Recruiting

The Effect of Exercise on Tumor Hypoxia in Men With Localized Prostate Cancer Undergoing Radical Prostatectomy.

Posted: September 18th, 2018, 2:00pm GMT

Condition: Prostate Cancer
Intervention: Behavioral: High Intensity Interval Training bout
Sponsor: Rigshospitalet, Denmark
Recruiting

Cabozantinib in Advanced Adrenocortical Carcinoma

Posted: August 2nd, 2018, 2:00pm GMT

Condition: Adrenocortical Carcinoma
Intervention: Drug: Cabozantinib-s-malate
Sponsor: Wuerzburg University Hospital
Recruiting

Permalink for 'Neoantigen DNA Vaccine in Combination With Nivolumab/Ipilimumab and PROSTVAC in Metastatic Hormone-Sensitive Prostate Cancer'

Neoantigen DNA Vaccine in Combination With Nivolumab/Ipilimumab and PROSTVAC in Metastatic Hormone-Sensitive Prostate Cancer

Posted: May 22nd, 2018, 2:00pm GMT

Condition: Metastatic Hormone-Sensitive Prostate Cancer
Interventions: Biological: PROSTVAC-V; Biological: PROSTVAC-F; Drug: Nivolumab; Drug: Ipilimumab; Biological: Neoantigen DNA vaccine; Device: TriGrid Delivery System; Procedure: Tumor biopsy; Procedure: Peripheral blood; Procedure: Fecal samples
Sponsors: Washington University School of Medicine; Bristol-Myers Squibb; Prostate Cancer Foundation
Recruiting

Neoplastic Barrett Esophagus: Endoscopic Piecemeal vs. En Bloc Resection

Posted: February 9th, 2018, 3:00pm GMT

Conditions: Barrett Esophagus; Barrett Adenocarcinoma; Esophagus Neoplasm
Interventions: Procedure: Endoscopic mucosal resection; Procedure: Endoscopic submucosal dissection
Sponsor: Universitätsklinikum Hamburg-Eppendorf
Recruiting

Registry of Endocrine Tumors (Thyroid, Parathyroid, Adrenal, Endocrine Pancreas, Endocrine Digestive Tube)

Posted: January 25th, 2018, 3:00pm GMT

Condition: Endocrine Tumor
Intervention:
Sponsor: Central Hospital, Nancy, France
Recruiting

Breast Cancer Screening: Digital Breast Tomosynthesis Versus Digital 2D Mammography

Posted: December 19th, 2017, 3:00pm GMT

Condition: Breast Cancer Screening
Interventions: Diagnostic Test: DBT+s2D; Diagnostic Test: 2D-FFDM
Sponsors: University Hospital Muenster; German Research Foundation
Recruiting

Clinical and Molecular Characteristics of Primary Aldosteronism in Blacks

Posted: December 15th, 2017, 3:00pm GMT

Conditions: Adrenal Gland Neoplasm; Hypertension; Bone Diseases, Metabolic; Cardiovascular Disease; Hyperinsulinemia
Intervention:
Sponsors: National Human Genome Research Institute (NHGRI); Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Recruiting

Cabozantinib in Treating Patients With Locally Advanced or Metastatic Unresectable Adrenocortical Carcinoma

Posted: December 12th, 2017, 3:00pm GMT

Conditions: Metastatic Carcinoma in the Adrenal Cortex; Stage III Adrenal Cortex Carcinoma AJCC v8; Stage IV Adrenal Cortex Carcinoma AJCC v8; Unresectable Adrenal Cortex Carcinoma
Interventions: Drug: Cabozantinib; Other: Pharmacogenomic Study; Other: Pharmacokinetic Study
Sponsors: M.D. Anderson Cancer Center; National Cancer Institute (NCI)
Recruiting

Fecal Microbiota Transplantation in Depression

Posted: September 13th, 2017, 2:00pm GMT

Condition: Major Depressive Disorder
Interventions: Drug: Fecal microbiota capsules; Drug: Placebo oral capsule
Sponsor: Psychiatric Hospital of the University of Basel
Recruiting

Over-the-scope Clips and Standard Treatments in Endoscopic Control of Acute Bleeding From Non-variceal Upper GI Causes

Posted: July 13th, 2017, 2:00pm GMT

Conditions: Acute Upper Gastrointestinal Bleeding; Tumor Bleeding
Interventions: Device: Over-the-scope Clips; Device: Hemo-clipping; Device: thermo-coagulation; Drug: Epinephrine
Sponsors: Chinese University of Hong Kong; Queen Mary Hospital, Hong Kong; The First Affiliated Hospital of Soochow University; Beijing Friendship Hospital; Zhejiang University; Ningbo No. 1 Hospital
Recruiting

Lu-177-DOTATATE (Lutathera) in Therapy of Inoperable Pheochromocytoma/ Paraganglioma

Posted: July 2nd, 2017, 2:00pm GMT

Conditions: Pheochromocytoma; Paraganglioma; Neuroendocrine Tumors; Neuroendocrine Neoplasms
Interventions: Drug: Lu-177-DOTATATE; Drug: Ga-68-DOTATATE; Drug: F-18-FDG; Drug: Amino Acid solution
Sponsor: National Cancer Institute (NCI)
Recruiting

Permalink for 'A Phase II Trial of the DNA Methyl Transferase Inhibitor, Guadecitabine (SGI-110), in Children and Adults With Wild Type GIST,Pheochromocytoma and Paraganglioma Associated With Succinate Dehydrogenase Deficiency and HLRCC-associated Kidney Cancer'

A Phase II Trial of the DNA Methyl Transferase Inhibitor, Guadecitabine (SGI-110), in Children and Adults With Wild Type GIST,Pheochromocytoma and Paraganglioma Associated With Succinate Dehydrogenase Deficiency and HLRCC-associated Kidney Cancer

Posted: May 24th, 2017, 2:00pm GMT

Conditions: Paraganglioma; Gastrointestinal Stromal Tumors; Carcinoma, Renal Cell; Renal Neoplasms; Pheochromocytoma
Intervention: Drug: SGI-110 (guadecitabine)
Sponsor: National Cancer Institute (NCI)
Recruiting

Propranolol Hydrochloride in Treating Patients With Prostate Cancer Undergoing Surgery

Posted: May 15th, 2017, 2:00pm GMT

Condition: Prostate Carcinoma
Interventions: Other: Laboratory Biomarker Analysis; Drug: Propranolol Hydrochloride; Other: Questionnaire Administration; Other: Survey Administration
Sponsors: Wake Forest University Health Sciences; National Cancer Institute (NCI)
Recruiting

Surgery and Heated Intraperitoneal Chemotherapy for Adrenocortical Carcinoma

Posted: April 25th, 2017, 2:00pm GMT

Conditions: Adrenocortical Carcinoma; Peritoneal Carcinomatosis
Interventions: Drug: Cisplatin; Drug: Sodium thiosulfate; Procedure: Cytoreductive surgery
Sponsor: Columbia University
Recruiting

Collection of Serum Samples in Studying Emotional Stress in Patients With Prostate Cancer

Posted: April 21st, 2017, 2:00pm GMT

Conditions: Hormone-Resistant Prostate Cancer; Recurrent Prostate Carcinoma; Stage I Prostate Cancer; Stage II Prostate Cancer; Stage IIA Prostate Cancer; Stage IIB Prostate Cancer
Interventions: Procedure: Biospecimen Collection; Other: Laboratory Biomarker Analysis; Other: Questionnaire Administration
Sponsors: Wake Forest University Health Sciences; National Cancer Institute (NCI)
Recruiting

Nivolumab in Treating Patients With Localized Kidney Cancer Undergoing Nephrectomy

Posted: February 16th, 2017, 3:00pm GMT

Conditions: Metastatic Malignant Neoplasm in Lymph Node; Metastatic Malignant Neoplasm in the Adrenal Gland; Metastatic Malignant Neoplasm in the Lung; Metastatic Malignant Neoplasm in the Pancreas; Metastatic Malignant Neoplasm in the Skin; Metastatic Malignant Neoplasm in the Soft Tissues; Metastatic Renal Cell Carcinoma; Oligometastasis; Sarcomatoid Renal Cell Carcinoma; Stage II Renal Cell Cancer AJCC v7; Stage III Renal Cell Cancer AJCC v7; Unclassified Renal Cell Carcinoma
Interventions: Procedure: Conventional Surgery; Biological: Nivolumab; Other: Patient Observation; Other: Quality-of-Life Assessment; Other: Questionnaire Administration
Sponsors: National Cancer Institute (NCI); Canadian Cancer Trials Group
Recruiting

Permalink for 'Functional Magnetic Resonance Imaging in Assessing Affect Reactivity and Regulation in Patients With Stage 0-III Breast Cancer'

Functional Magnetic Resonance Imaging in Assessing Affect Reactivity and Regulation in Patients With Stage 0-III Breast Cancer

Posted: February 13th, 2017, 3:00pm GMT

Conditions: Healthy Subject; Stage 0 Breast Cancer; Stage IA Breast Cancer; Stage IB Breast Cancer; Stage IIA Breast Cancer; Stage IIB Breast Cancer; Stage IIIA Breast Cancer; Stage IIIB Breast Cancer; Stage IIIC Breast Cancer
Interventions: Procedure: Biospecimen Collection; Procedure: Functional Magnetic Resonance Imaging; Other: Questionnaire Administration
Sponsors: Stanford University; National Cancer Institute (NCI)
Recruiting

Familial Investigations of Childhood Cancer Predisposition

Posted: February 10th, 2017, 3:00pm GMT

Conditions: Acute Leukemia; Adenomatous Polyposis; Adrenocortical Carcinoma; AML; BAP1 Tumor Predisposition Syndrome; Carney Complex; Choroid Plexus Carcinoma; Constitutional Mismatch Repair Deficiency Syndrome; Diamond-Blackfan Anemia; DICER1 Syndrome; Dyskeratosis Congenita; Emberger Syndrome; Familial Acute Myeloid Leukemia; Familial Adenomatous Polyposis; Fanconi Anemia; Familial Cancer; Familial Wilms Tumor; Familial Neuroblastoma; GIST; Hereditary Breast and Ovarian Cancer; Hereditary Paraganglioma-Pheochromocytoma Syndrome; Hodgkin Lymphoma; Juvenile Polyposis; Li-Fraumeni Syndrome; Lynch Syndrome; MDS; Melanoma Syndrome; Multiple Endocrine Neoplasia Type 1; Multiple Endocrine Neoplasia Type 2; Neuroblastoma; Neurofibromatosis Type 1; Neurofibromatosis Type II; Nevoid Basal Cell Carcinoma Syndrome; Non Hodgkin Lymphoma; Noonan Syndrome and Other Rasopathy; Overgrowth Syndromes; Pancreatic Cancer; Peutz-Jeghers Syndrome; Pheochromocytoma/Paraganglioma; PTEN Hamartoma Tumor Syndrome; Retinoblastoma; Rhabdoid Tumor Predisposition Syndrome; Rhabdomyosarcoma; Rothmund-Thomson Syndrome; Tuberous Sclerosis; Von Hippel-Lindau Disease
Intervention:
Sponsor: St. Jude Children's Research Hospital
Recruiting

Study of Biomarker-Based Treatment of Acute Myeloid Leukemia

Posted: January 9th, 2017, 3:00pm GMT

Condition: Previously Untreated Acute Myeloid Leukemia
Interventions: Biological: Samalizumab (BAML-16-001-S1); Biological: BI 836858 (BAML-16-001-S2); Other: Laboratory Biomarker Analysis; Drug: Daunorubicin (BAML-16-001-S1); Drug: Cytarabine (BAML-16-001-S1); Drug: Azacitidine (BAML-16-001-S2); Drug: AG-221 (BAML-16-001-S3); Drug: Azacitidine (BAML-16-001-S3); Drug: Entospletinib (BAML-16-001-S4); Drug: Azacitidine (BAML-16-001-S4); Drug: Entospletinib (BAML-16-001-S5); Drug: Decitabine (BAML-16-001-S5); Drug: Entospletinib (BAML-16-001-S6); Drug: Azacitidine (BAML-16-001-S6); Drug: Daunorubicin (BAML-16-001-S6); Drug: Cytarabine (BAML-16-001-S6); Drug: Pevonedistat (BAML-16-001-S9); Drug: Azacitidine (BAML-16-001-S9); Drug: AG-120 (BAML-16-001-S16); Drug: Azacitidine (BAML-16-001-S16); Drug: Gilteritinib (BAML-16-001-S8); Drug: Decitabine (BAML-16-001-S8)
Sponsor: Beat AML, LLC
Recruiting

Permalink for 'Lenvatinib in Treating Patients With Metastatic or Advanced Pheochromocytoma or Paraganglioma That Cannot Be Removed by Surgery'

Lenvatinib in Treating Patients With Metastatic or Advanced Pheochromocytoma or Paraganglioma That Cannot Be Removed by Surgery

Posted: January 2nd, 2017, 3:00pm GMT

Conditions: Malignant Adrenal Gland Pheochromocytoma; Malignant Paraganglioma; Metastatic Adrenal Gland Pheochromocytoma
Interventions: Other: Laboratory Biomarker Analysis; Drug: Lenvatinib; Other: Quality-of-Life Assessment
Sponsors: Mayo Clinic; National Cancer Institute (NCI)
Recruiting

Cryobiopsy Versus Forceps Biopsy for Pulmonary Lesions

Posted: December 6th, 2016, 3:00pm GMT

Conditions: Solitary Pulmonary Nodule; Multiple Pulmonary Nodules
Intervention: Procedure: transbronchial biopsy
Sponsors: University of Pennsylvania; Andrew Haas; Anil Vachani; Anthony Lanfranco; Kevin Ma; Jeffrey Thompson; Edmund Moon
Recruiting

The MATCH Study: Mindfulness And Tai Chi for Cancer Health

Posted: June 15th, 2016, 2:00pm GMT

Condition: Cancer
Interventions: Behavioral: Mindfulness Based Cancer Recovery (MBCR); Behavioral: Tai Chi/Qigong (TCQ) for Cancer Patients
Sponsors: Linda E. Carlson; University of Calgary; Alberta Health Services; Tom Baker Cancer Centre; Princess Margaret Hospital, Canada
Recruiting

Evaluate Use of Caudal Nerve Blocks in Adult Penile Prosthesis

Posted: April 15th, 2016, 2:00pm GMT

Condition: Malignant Neoplasms of Male Genital Organs
Interventions: Procedure: Caudal Nerve Block (CNB); Drug: Ropivacaine; Drug: Epinephrine; Drug: Decadron; Drug: Clonidine; Drug: Propofol; Behavioral: Phone Call
Sponsors: M.D. Anderson Cancer Center; Merck Sharp & Dohme Corp.
Recruiting

Pembrolizumab in Treating Patients With Rare Tumors That Cannot Be Removed by Surgery or Are Metastatic

Posted: March 29th, 2016, 2:00pm GMT

Conditions: Carcinoma of Unknown Primary Origin; Kidney Medullary Carcinoma; Malignant Germ Cell Tumor; Metastatic Adrenal Gland Pheochromocytoma; Metastatic Malignant Solid Neoplasm; Metastatic Paraganglioma; Metastatic Penile Carcinoma; Paraganglioma; Skin Squamous Cell Carcinoma; Small Cell Carcinoma; Stage IV Adrenal Cortex Carcinoma AJCC v7; Stage IV Penile Cancer AJCC v7; Stage IV Renal Cell Cancer AJCC v7; Unresectable Solid Neoplasm; Vascular Neoplasm
Interventions: Other: Laboratory Biomarker Analysis; Biological: Pembrolizumab; Other: Questionnaire Administration
Sponsors: M.D. Anderson Cancer Center; National Cancer Institute (NCI)
Recruiting

Single Agent Pembrolizumab in Subjects With Advanced Adrenocortical Carcinoma

Posted: February 3rd, 2016, 3:00pm GMT

Condition: Adrenocortical Carcinoma
Intervention: Drug: Pembrolizumab
Sponsors: Memorial Sloan Kettering Cancer Center; Merck Sharp & Dohme Corp.
Recruiting

A Dose-Escalation Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of IPI-549

Posted: December 22nd, 2015, 3:00pm GMT

Conditions: Advanced Solid Tumors (Part A/B/C/D); Non-small Cell Lung Cancer (Part E); Melanoma (Part E); Squamous Cell Cancer of the Head and Neck (Part E); Triple Negative Breast Cancer (Part F); Adrenocortical Carcinoma (Part G); Mesothelioma (Part G); High-circulating Myeloid-derived Suppressor Cells (Part H)
Interventions: Drug: IPI-549; Drug: Nivolumab
Sponsor: Infinity Pharmaceuticals, Inc.
Recruiting

Exercise Intervention for LGBT Cancer Survivors

Posted: June 2nd, 2015, 2:00pm GMT

Condition: Neoplasms
Intervention: Behavioral: Exercise for Cancer Patients
Sponsor: University of Rochester
Recruiting

The Effect of the Serratus Block on Pain Control After Breast Surgery

Posted: May 25th, 2015, 2:00pm GMT

Condition: Anesthesia
Interventions: Procedure: Serratus Block; Procedure: Placebo Block; Drug: ropivacaine; Drug: epinephrine; Other: sterile saline
Sponsor: Women's College Hospital
Recruiting

USDA Western Human Nutrition Research Center (WHNRC) Cross-Sectional Nutritional Phenotyping Study

Posted: February 20th, 2015, 3:00pm GMT

Conditions: Obesity; Inflammation
Intervention:
Sponsor: USDA, Western Human Nutrition Research Center
Recruiting

Structured Evaluation of adRENal Tumors Discovered Incidentally - Prospectively Investigating the Testing Yield

Posted: December 24th, 2014, 3:00pm GMT

Conditions: Adrenal Incidentaloma; Adrenocortical Carcinoma
Intervention:
Sponsors: University Medical Center Groningen; Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA); VU University Medical Center; Radboud University; Leiden University Medical Center; Maastricht University Medical Center; UMC Utrecht; Erasmus Medical Center; Martini Hospital Groningen; Canisius-Wilhelmina Hospital; Diakonessenhuis, Utrecht; Isala; Haga Hospital; St. Antonius Hospital; Kennemer Gasthuis; Maxima Medical Center; Medical Center Alkmaar; Medical Centre Leeuwarden; Meander Medical Center; Medisch Spectrum Twente; Onze Lieve Vrouwe Gasthuis; Rijnstate Hospital; Elisabeth-TweeSteden Ziekenhuis; Tergooi Hospital; Vlietland Ziekenhuis; Scheper Hospital; Flevo Hospital
Recruiting

Permalink for 'Study to Evaluate the Effects of Cabozantinib in Patients With Unresectable Metastatic Pheochromocytomas and Paragangliomas'

Study to Evaluate the Effects of Cabozantinib in Patients With Unresectable Metastatic Pheochromocytomas and Paragangliomas

Posted: November 27th, 2014, 3:00pm GMT

Conditions: Locally Advanced Paraganglioma; Metastatic Adrenal Gland Pheochromocytoma; Metastatic Paraganglioma; Regional Adrenal Gland Pheochromocytoma; Unresectable Adrenal Gland Pheochromocytoma; Unresectable Paraganglioma
Interventions: Drug: Cabozantinib S-malate; Other: Laboratory Biomarker Analysis; Other: Questionnaire Administration
Sponsors: M.D. Anderson Cancer Center; National Cancer Institute (NCI)
Recruiting

Phase I/II Study of MEK162 for Children With Ras/Raf Pathway Activated Tumors

Posted: November 7th, 2014, 3:00pm GMT

Conditions: Low-Grade Gliomas; Malignant Neoplasms, Brain; Soft Tissue Neoplasms
Intervention: Drug: MEK162
Sponsors: Children's Hospital Los Angeles; Dana-Farber Cancer Institute
Recruiting

Phase II Study of Proton Radiation Therapy for Neuroblastoma

Posted: April 14th, 2014, 2:00pm GMT

Conditions: Neuroblastoma; Ganglioneuroblastoma
Intervention: Radiation: Proton Beam Radiation Therapy
Sponsors: Massachusetts General Hospital; National Cancer Institute (NCI)
Recruiting

Effect of Chronic Catecholamine Overproduction on Brown Adipose Tissue

Posted: September 24th, 2013, 2:00pm GMT

Conditions: Pheochromocytoma; Adrenal Incidentaloma
Intervention: Procedure: Removal of adrenal tumor
Sponsor: University of Aarhus
Recruiting

A Phase IV Post Approval Clinical Study of ExAblate Treatment of Metastatic Bone Tumors for the Palliation of Pain

Posted: April 17th, 2013, 2:00pm GMT

Condition: Bone Metastasis
Intervention: Device: ExAblate MRgFUS
Sponsor: InSightec
Recruiting

Long-term Beneficial Metabolic Effects of Adrenalectomy in Subclinical Cushing's Syndrome of Adrenal Incidentaloma

Posted: June 27th, 2011, 2:00pm GMT

Condition: Cushing Syndrome
Intervention: Procedure: surgery
Sponsors: Samsung Medical Center; Asan Medical Center; Severance Hospital; Konkuk University Medical Center
Recruiting

Androgen-Deprivation Therapy and Radiation Therapy in Treating Patients With Prostate Cancer

Posted: June 8th, 2011, 2:00pm GMT

Condition: Prostate Cancer
Interventions: Radiation: radiation therapy; Radiation: Whole-pelvic radiotherapy (WPRT)
Sponsors: Radiation Therapy Oncology Group; National Cancer Institute (NCI); NRG Oncology
Recruiting

Adrenalectomy Versus Follow-up in Patients With Subclinical Cushings Syndrome

Posted: November 23rd, 2010, 3:00pm GMT

Condition: Adrenal Tumour With Mild Hypercortisolism
Intervention: Procedure: Adrenalectomy
Sponsor: Region Skane
Recruiting

Prospective Comprehensive Molecular Analysis of Endocrine Neoplasms

Posted: November 2nd, 2009, 3:00pm GMT

Conditions: Endocrine Tumors; Thyroid Neoplasms; Parathyroid Neoplasms; Adrenal Neoplasm; Neuroblastoma
Intervention:
Sponsor: National Cancer Institute (NCI)
Recruiting

Molecular Characterization of Neuroblastic Tumor: Correlation With Clinical Outcome

Posted: January 8th, 2008, 3:00pm GMT

Condition: Neuroblastoma
Intervention: Other: Tumor and Marrow Markers
Sponsors: Memorial Sloan Kettering Cancer Center; Southern Illinois University; Spanish National Cancer Center; St. Jude Children's Research Hospital; Washington University School of Medicine; University of Texas; Weill Medical College of Cornell University
Recruiting

Study of Adrenal Gland Tumors

Posted: June 29th, 2000, 2:00pm GMT

Condition: Adrenal Gland Neoplasm
Intervention:
Sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Recruiting

Rare Cancer News & Clinical Trials » Trial - Adrenal Cancer

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Trial - Adrenal Cancer (63 unread)