Condition: Post-thoracotomy Pain Syndrome
Intervention: Procedure: Thoracic epidural analgesia , superficial serratus plane block and deep serratus plane block
Sponsor: National Cancer Institute, Egypt
Recruiting
Feeds
54593 items (54593 unread) in 74 feeds
Acinar Cell Carcinoma
(336 unread)
Acinic Cell Carcinoma
(249 unread)
Adenoid Cystic Carcinoma
(1041 unread)
Adrenal Gland Cancer
(4874 unread)
Ampulla Of Vater
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Anal Cancer
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Angiosarcoma
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Appendix Cancer
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Bile Duct Cancer
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Brain and CNS
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Carcinoid
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Endocrine/Neuroendocrine
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Gall Bladder Cancer
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Hemangioendothelioma
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Hepatoblastoma
(761 unread)
Pancreas
(751 unread)
Phyllodes
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PMP and Mucinous Tumors
(472 unread)
Rhabdomyosarcoma
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Sarcoma
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Trial - Adrenal Cancer (81 unread)
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The Effect of Ultrasound Guided Superficial, Deep Serratus Plane Blocks and Thoracic Epidural in Thoracotomy
Posted: December 6th, 2019, 3:00pm GMT
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A Novel Therapeutic Vaccine (EO2401) in Metastatic Adrenocortical Carcinoma, or Malignant Pheochromocytoma/Paraganglioma
Posted: December 5th, 2019, 3:00pm GMT
Conditions: Adrenocortical Carcinoma; Pheochromocytoma; Paraganglioma
Intervention: Biological: EO2401
Sponsor: Enterome
Not yet recruiting -
Effects of Pre-emptive Scalp Infiltration With Ketorolac and Ropivacaine for Post-craniotomy Pain
Posted: October 28th, 2019, 2:00pm GMT
Conditions: Pain; Supratentorial Brain Tumor
Interventions: Drug: Ketorolac; Drug: Ropivacaine; Drug: Epinephrine
Sponsor: Beijing Tiantan Hospital
Not yet recruiting -
Impact of Adrenal IncidenTalomas and Possible Autonomous Cortisol Secretion on Cardiovascular and Metabolic Alterations
Posted: October 15th, 2019, 2:00pm GMT
Conditions: Adrenal Incidentaloma; Hypercortisolism; Adrenal Tumor
Intervention: Procedure: Adrenalectomy
Sponsor: University of Roma La Sapienza
Recruiting -
Radioactive Drug (177Lu-DOTATATE) for the Treatment of Locally Advanced, Metastatic, or Unresectable Rare Endocrine Cancers
Posted: September 27th, 2019, 2:00pm GMT
Conditions: Locally Advanced Adrenal Gland Pheochromocytoma; Locally Advanced Paraganglioma; Metastatic Adrenal Gland Pheochromocytoma; Metastatic Paraganglioma; Metastatic Parathyroid Gland Carcinoma; Pituitary Gland Carcinoma; Somatostatin Receptor Positive; Stage III Thyroid Gland Medullary Carcinoma AJCC v8; Stage IV Thyroid Gland Medullary Carcinoma AJCC v8; Stage IVA Thyroid Gland Medullary Carcinoma AJCC v8; Stage IVB Thyroid Gland Medullary Carcinoma AJCC v8; Stage IVC Thyroid Gland Medullary Carcinoma AJCC v8; Unresectable Adrenal Gland Pheochromocytoma; Unresectable Paraganglioma
Intervention: Drug: Lutetium Lu 177 Dotatate
Sponsors: M.D. Anderson Cancer Center; National Cancer Institute (NCI)
Not yet recruiting -
Study of ASP1948, Targeting an Immune Modulatory Receptor, in Japanese Patients With Advanced Solid Tumors
Posted: September 19th, 2019, 2:00pm GMT
Condition: Locally Advanced (Unresectable) or Metastatic Solid Tumor Malignancies
Intervention: Drug: ASP1948
Sponsor: Astellas Pharma Inc
Recruiting -
Exparel Injection Effect on Postoperative Opioid Usage
Posted: September 11th, 2019, 2:00pm GMT
Conditions: Thyroid; Parathyroid Adenoma
Interventions: Drug: Lidocaine Epinephrine; Drug: Bupivacaine Hydrochloride-EPINEPHrine; Drug: Lidocaine Epinephrine, Bupivacaine Hydrochloride-EPINEPHrine
Sponsor: University of Missouri-Columbia
Not yet recruiting -
ESP Block for Laparoscopic Nephrectomy Surgeries
Posted: September 11th, 2019, 2:00pm GMT
Conditions: Nephrectomy, Anesthesia, Regional, Patient-controlled, Analgesia; Kidney Diseases
Interventions: Drug: Ropivacaine injection; Other: Sham
Sponsors: McMaster University; St. Joseph's Healthcare Hamilton
Not yet recruiting -
Biological Response to Brief Psychological Challenge
Posted: September 4th, 2019, 2:00pm GMT
Condition: Acute Inflammatory Response to Psychological Stress
Interventions: Behavioral: Socio-evaluative speech task, then Control; Behavioral: Control, then Socio-evaluative speech task
Sponsors: University of Pittsburgh; National Institute of Mental Health (NIMH)
Not yet recruiting -
Dose-Escalation and Efficacy Study of LAE001/Prednisone Plus Afuresertib Patients With m-CRPC
Posted: August 19th, 2019, 2:00pm GMT
Condition: Metastatic Castration-resistant Prostate Cancer
Intervention: Drug: Phase I and Phase II: LAE001/prednisone + afuresertib
Sponsor: Laekna Limited
Recruiting -
Acute Effect of modeRate-intensity aerOBIc Exercise on Colon Cancer Cell Growth
Posted: August 15th, 2019, 2:00pm GMT
Conditions: Colon Adenocarcinoma; Colon Cancer
Intervention: Other: Exercise assessment
Sponsors: Northumbria University; York St John University; Newcastle University
Recruiting -
Analgesic Effect of Adding Thoracic Paravertebral Nerve Blocks to Modified PEC Block in Breast Cancer Surgery
Posted: August 14th, 2019, 2:00pm GMT
Conditions: Breast Cancer Female; Pain, Postoperative
Interventions: Procedure: Thoracic paravertebral block under ultrasound guidance; Procedure: Intraoperative modified PEC block; Procedure: GA with ETT
Sponsor: Mahidol University
Recruiting -
RCT of Gastric ESD With or Without Epineprhine Added Solution
Posted: July 25th, 2019, 2:00pm GMT
Conditions: Gastric Neoplasm; Early Gastric Cancer
Interventions: Procedure: Endoscopic submucosal dissection; Drug: Epinephrine
Sponsors: Chinese University of Hong Kong; Osaka International Cancer Institute; Shizuoka Cancer Center; Fukuoka University; Changi General Hospital; Kyoto 2nd Red Cross Hospital; Ishikawa Prefectural Central Hospital; Kosin University Gospel Hospital
Recruiting -
The Master Registry of Oncology Outcomes Associated With Testing and Treatment
Posted: July 22nd, 2019, 2:00pm GMT
Conditions: Adenocarcinoma; Adenocystic Carcinoma; Anal Cancer; Appendix Cancer; Brain Tumor; Glioblastoma; Astrocytoma; Bile Duct Cancer; Cholangiocarcinoma; Bladder Cancer; Bone Cancer; Synovial Sarcoma; Chondrosarcoma; Liposarcoma; Sarcoma, Kaposi; Sarcoma,Soft Tissue; Sarcoma; Osteosarcoma; CNS Cancer; Brain Stem Neoplasms; Breast Cancer; Cervical Cancer; Colorectal Cancer; Rectal Cancer; Colon Cancer; Esophageal Cancer; Esophagus Cancer; Cancer of Colon; Pancreatic Cancer; Cancer of Pancreas; Testis Cancer; Testicular Cancer; Ureter Cancer; Renal Cell Carcinoma; Kidney Cancer; Gestational Trophoblastic Tumor; Head and Neck Neoplasms; Parotid Tumor; Larynx Cancer; Tongue Cancer; Pharynx Cancer; Salivary Gland Cancer; Acute Myeloid Leukemia; Chronic Myeloid Leukemia; Acute Lymphoblastic Leukemia; Multiple Myeloma; Non Hodgkin Lymphoma; Carcinoid Tumor; Lung Cancer; Neuroendocrine Tumors; Mesothelioma; Thyroid Cancer; Parathyroid Neoplasms; Adrenal Cancer; Small Bowel Cancer; Stomach Cancer; Liver Cancer; Hepatic Cancer; Melanoma; Skin Cancer; Unknown Primary Tumors; Uterine Cancer; Fallopian Tube Cancer; Ovarian Cancer; Prostate Cancer; Vaginal Cancer; Penile Cancer; Vulvar Cancer; Waldenstrom Macroglobulinemia; Cancer, Advanced; Thymus Cancer; Nasopharyngeal Carcinoma; Multiple Endocrine Neoplasia; Pheochromocytoma; Small Cell Carcinoma; Pulmonary Carcinoma
Interventions: Diagnostic Test: Testing: Genome; Diagnostic Test: Testing: Transcriptome; Diagnostic Test: Testing: Proteome; Drug: Treatment: CAR-T
Sponsor: Taproot Health
Not yet recruiting -
Paravertebral Block Versus Thoracic Epidural Analgesia
Posted: July 19th, 2019, 2:00pm GMT
Conditions: Lung Cancer; Postoperative Pain
Interventions: Drug: Thoracic epidural; Drug: Paravertebral block
Sponsor: St. Olavs Hospital
Recruiting -
Preoperative Pectoral Nerve Block for Acute and Chronic Post-Operative Pain Following Mastectomy
Posted: July 15th, 2019, 2:00pm GMT
Conditions: Breast Cancer; Mastectomy; Anesthesia, Local; Narcotic Use
Interventions: Drug: PECs block with local anesthesia of bupivacaine with steroid; Other: Placebo PECs block with normal saline
Sponsor: University of Alabama at Birmingham
Not yet recruiting -
Primary Aldosteronism and Surgically Curable Forms in Hypertension Patients Using 11C-Metomidate
Posted: June 19th, 2019, 2:00pm GMT
Conditions: Primary Aldosteronism; Primary Aldosteronism Due to Aldosterone Producing Adenoma
Intervention: Combination Product: 11C-Metomidate PET/CT Scan
Sponsors: Changi General Hospital; National University Health System, Singapore; Clinical Imaging Research Centre; Singapore General Hospital; Tan Tock Seng Hospital; Khoo Teck Puat Hospital; Ng Teng Fong General Hospital
Recruiting -
Cryoablation of Bone Metastases From Endocrine Tumors
Posted: June 14th, 2019, 2:00pm GMT
Conditions: Neoplasm Metastasis; Thyroid Neoplasm; Pheochromocytoma; Adrenal Neoplasm; Neuroendocrine Tumors; Bone Metastases
Intervention: Device: cryoablation
Sponsors: Instituto do Cancer do Estado de São Paulo; University of Sao Paulo General Hospital
Recruiting -
AKT Inhibitor, Ipatasertib, With Endocrine and CDK 4/6 Inhibitor for Patients With Metastatic Breast Cancer (TAKTIC)
Posted: May 22nd, 2019, 2:00pm GMT
Condition: Breast Cancer
Interventions: Drug: Ipatasertib; Drug: Fulvestrant; Drug: Aromatase Inhibitor; Drug: Palbociclib
Sponsors: Massachusetts General Hospital; Genentech, Inc.
Recruiting -
Colorectal Metastasis Prevention International Trial 2
Posted: April 18th, 2019, 2:00pm GMT
Condition: Colorectal Neoplasms
Interventions: Drug: Propranolol and etodolac; Other: Placebo
Sponsors: Assaf-Harofeh Medical Center; Sheba Medical Center; Rabin Medical Center; Tel-Aviv Sourasky Medical Center; Rambam Health Care Campus; HaEmek Medical Center, Israel
Recruiting -
Erector Spinae Plane Block Versus Intercostal for VATS
Posted: April 4th, 2019, 2:00pm GMT
Conditions: Lung Cancer; Lung Diseases
Interventions: Procedure: ESP block; Procedure: Intercostal block; Procedure: Sham ESP block; Procedure: Sham Intercostal block; Drug: Bupivacaine-epinephrine; Drug: Dexamethasone injection; Drug: Normal saline
Sponsor: McGill University Health Center
Recruiting -
The PIONEER Initiative: Precision Insights On N-of-1 Ex Vivo Effectiveness Research Based on Individual Tumor Ownership (Precision Oncology)
Posted: April 1st, 2019, 2:00pm GMT
Conditions: Cancer, All Types; Cancer of Liver; Cancer of Stomach; Cancer of Head and Neck; Cancer of Rectum; Cancer of Kidney; Cancer of Esophagus; Cancer of Colon; Cancer Skin; Cancer of Cervix; Cancer, Metastatic; Cancer of Larynx; Cancer of Neck; Cancer of Lung; Cancer of Brain and Nervous System; Cancer of Vulva, Disseminated; Cancer of Pancreas; Sarcoma; GIST; Small-cell Lung Cancer; Adenocarcinoma Lung; Cancer of Prostate; Cancer, Advanced; Adrenal Cancer; Testicular Cancer; Uterine Cancer; Bronchoalveolar Cell Lung Cancer; Cancer Unknown Primary; Glioblastoma Multiforme; Oligodendroglioma; Breast Cancer; Renal Cell Carcinoma; Hepatocellular Carcinoma; Cholangiocarcinoma; Squamous Cell Carcinoma; Transitional Cell Carcinoma; Cancer, Other; Cancer, Anal; Melanoma; Cancer, Bile Duct; Cancer, Bladder; Cancer Cords Vocal; Cancers Cell Neuroendocrine; Cancer Differentiated Poorly; Cancer, Anaplastic Thyroid
Intervention:
Sponsors: SpeciCare; Dana-Farber Cancer Institute; Kalispell Regional Medical Center; Georgia Institute of Technology; Ontario Institute for Cancer Research; SEngine Precision Medicine; Helomics
Recruiting -
Comparing the Efficacy of Local Anesthetics in Mohs Surgery
Posted: March 12th, 2019, 2:00pm GMT
Conditions: Lidocaine; Bupivacaine; Mohs Surgery; Anesthetic
Interventions: Drug: Lidocaine; Drug: Bupivacaine; Drug: Lidocaine and Bupivacaine
Sponsors: Ottawa Hospital Research Institute; Richard J. MacKay Endowment Fund; Benefactor Life Members’ Research Grant; The Ottawa Hospital Division of Dermatology
Not yet recruiting -
Stereotactic Ablative Radiotherapy for Comprehensive Treatment of Oligometastatic (1-3 Metastases) Cancer
Posted: March 5th, 2019, 3:00pm GMT
Condition: Metastatic Tumors
Interventions: Radiation: palliative radiotherapy; Radiation: Stereotactic ablative radiotherapy
Sponsors: British Columbia Cancer Agency; London Regional Cancer Program, Canada; Beatson Institute for Cancer Research, Scotland; The Alfred; Beacon Hospital, Ireland
Recruiting -
Perioperative Intervention to Reduce Metastatic Processes in Pancreatic Cancer Patients Undergoing Curative Surgery
Posted: February 12th, 2019, 3:00pm GMT
Condition: Pancreatic Neoplasms
Interventions: Drug: Propranolol and etodolac; Other: Placebo
Sponsors: Assaf-Harofeh Medical Center; Sheba Medical Center
Recruiting -
Analgesia of Erector Spinae Plane Block Versus Quadratus Lumborum Block
Posted: January 14th, 2019, 3:00pm GMT
Condition: Colorectal Cancer
Interventions: Other: Erector spinae plane block; Other: Quadratus lumborum block; Drug: Propofol; Drug: Fentanyl NCS; Drug: Atracurium Injectable Product; Other: Endotracheal intubation; Drug: Anesthesia Maintenance; Drug: Muscle Relaxation
Sponsor: Mansoura University
Not yet recruiting -
A Study of ASP1951 in Subjects With Advanced Solid Tumors
Posted: January 10th, 2019, 3:00pm GMT
Condition: Advanced Solid Tumors
Interventions: Drug: ASP1951; Drug: pembrolizumab
Sponsor: Astellas Pharma Global Development, Inc.
Recruiting -
Conventional ADT w/ or w/Out Abiraterone Acetate + Prednisone and Apalutamide Following a Detectable PSA After Radiation and ADT
Posted: December 18th, 2018, 3:00pm GMT
Condition: Prostate Cancer
Interventions: Drug: Prednisone; Drug: Apalutamide; Drug: Abiraterone Acetate; Drug: LHRH Agonist or Antagonist
Sponsors: Dana-Farber Cancer Institute; Janssen Scientific Affairs, LLC
Recruiting -
Adjuvant Endocrine Therapy in Early Stage Breast Cancer: Adherence and Clinical Outcome
Posted: December 3rd, 2018, 3:00pm GMT
Condition: Breast Neoplasm
Intervention:
Sponsors: St. Olavs Hospital; Norwegian University of Science and Technology
Recruiting -
SABR for Renal Tumors
Posted: November 20th, 2018, 3:00pm GMT
Condition: Renal Tumor
Intervention: Radiation: Stereotactic Ablative Radiotherapy
Sponsor: University Health Network, Toronto
Recruiting -
Prospective Trial of Digital Breast Tomosynthesis (DBT) in Breast Cancer Screening.
Posted: November 7th, 2018, 3:00pm GMT
Condition: Breast Cancer
Interventions: Diagnostic Test: digital breast tomosynthesis; Diagnostic Test: standard two dimension digital mammogram
Sponsor: King's College Hospital NHS Trust
Recruiting -
Mid-point Transverse Process to Pleura Block for Breast Cancer Surgery: A Randomized Controlled Trial
Posted: October 19th, 2018, 2:00pm GMT
Conditions: Breast Cancer; Acute Pain; Anesthesia
Interventions: Procedure: PVB group; Procedure: MTP block group; Procedure: Control Group
Sponsor: Ottawa Hospital Research Institute
Not yet recruiting -
Functional MRI Study Reconstructed Breasts
Posted: October 11th, 2018, 2:00pm GMT
Condition: Breast Cancer
Intervention: Device: MRI scan
Sponsor: Maastricht University Medical Center
Recruiting -
The Effect of Exercise on Tumor Hypoxia in Men With Localized Prostate Cancer Undergoing Radical Prostatectomy.
Posted: September 18th, 2018, 2:00pm GMT
Condition: Prostate Cancer
Intervention: Behavioral: High Intensity Interval Training bout
Sponsor: Rigshospitalet, Denmark
Recruiting -
Cabozantinib in Advanced Adrenocortical Carcinoma
Posted: August 2nd, 2018, 2:00pm GMT
Condition: Adrenocortical Carcinoma
Intervention: Drug: Cabozantinib-s-malate
Sponsor: Wuerzburg University Hospital
Recruiting -
Mitotane With or Without Cisplatin and Etoposide After Surgery in Treating Participants With Stage I-III Adrenocortical Cancer With High Risk of Recurrence (ADIUVO-2)
Posted: July 11th, 2018, 2:00pm GMT
Conditions: ENSAT Stage I Adrenal Cortex Carcinoma; ENSAT Stage II Adrenal Cortex Carcinoma; ENSAT Stage III Adrenal Cortex Carcinoma
Interventions: Drug: Cisplatin; Drug: Etoposide; Drug: Mitotane; Procedure: Quality-of-Life Assessment
Sponsors: M.D. Anderson Cancer Center; Amercian Australian Asian Adrenal Alliance (A5); European Network for the Study of Adrenal Tumors (ENS@T)
Recruiting -
Neoantigen DNA Vaccine in Combination With Nivolumab/Ipilimumab and PROSTVAC in Metastatic Hormone-Sensitive Prostate Cancer
Posted: May 22nd, 2018, 2:00pm GMT
Condition: Metastatic Hormone-Sensitive Prostate Cancer
Interventions: Biological: PROSTVAC-V; Biological: PROSTVAC-F; Drug: Nivolumab; Drug: Ipilimumab; Biological: Neoantigen DNA vaccine; Device: TriGrid Delivery System; Procedure: Tumor biopsy; Procedure: Peripheral blood; Procedure: Fecal samples; Procedure: Leukapheresis
Sponsors: Washington University School of Medicine; Bristol-Myers Squibb; Prostate Cancer Foundation; BJH Foundation
Recruiting -
Neoplastic Barrett Esophagus: Endoscopic Piecemeal vs. En Bloc Resection
Posted: February 9th, 2018, 3:00pm GMT
Conditions: Barrett Esophagus; Barrett Adenocarcinoma; Esophagus Neoplasm
Interventions: Procedure: Endoscopic mucosal resection; Procedure: Endoscopic submucosal dissection
Sponsor: Universitätsklinikum Hamburg-Eppendorf
Recruiting -
Registry of Endocrine Tumors (Thyroid, Parathyroid, Adrenal, Endocrine Pancreas, Endocrine Digestive Tube)
Posted: January 25th, 2018, 3:00pm GMT
Condition: Endocrine Tumor
Intervention:
Sponsor: Central Hospital, Nancy, France
Recruiting -
Breast Cancer Screening: Digital Breast Tomosynthesis Versus Digital 2D Mammography
Posted: December 19th, 2017, 3:00pm GMT
Condition: Breast Cancer Screening
Interventions: Diagnostic Test: DBT+s2D; Diagnostic Test: 2D-FFDM
Sponsors: University Hospital Muenster; German Research Foundation
Recruiting -
Clinical and Molecular Characteristics of Primary Aldosteronism in Blacks
Posted: December 15th, 2017, 3:00pm GMT
Conditions: Adrenal Gland Neoplasm; Hypertension; Bone Diseases, Metabolic; Cardiovascular Disease; Hyperinsulinemia
Intervention:
Sponsors: National Human Genome Research Institute (NHGRI); Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Recruiting -
Cabozantinib in Treating Patients With Locally Advanced or Metastatic Unresectable Adrenocortical Carcinoma
Posted: December 12th, 2017, 3:00pm GMT
Conditions: Metastatic Carcinoma in the Adrenal Cortex; Stage III Adrenal Cortex Carcinoma AJCC v8; Stage IV Adrenal Cortex Carcinoma AJCC v8; Unresectable Adrenal Cortex Carcinoma
Interventions: Drug: Cabozantinib; Other: Pharmacogenomic Study; Other: Pharmacokinetic Study
Sponsors: M.D. Anderson Cancer Center; National Cancer Institute (NCI)
Recruiting -
Evaluation of Effects of Estetrol on Testosterone Suppression and Quality of Life in Prostate Cancer Patients Treated With an LHRH Agonist.
Posted: December 5th, 2017, 3:00pm GMT
Condition: Prostatic Neoplasm
Interventions: Drug: Estetrol; Drug: Placebo Oral Tablet
Sponsor: Pantarhei Oncology B.V.
Recruiting -
Fecal Microbiota Transplantation in Depression
Posted: September 13th, 2017, 2:00pm GMT
Condition: Major Depressive Disorder
Interventions: Drug: Fecal microbiota capsules; Drug: Placebo oral capsule
Sponsor: Psychiatric Hospital of the University of Basel
Recruiting -
Over-the-scope Clips and Standard Treatments in Endoscopic Control of Acute Bleeding From Non-variceal Upper GI Causes
Posted: July 13th, 2017, 2:00pm GMT
Conditions: Acute Upper Gastrointestinal Bleeding; Tumor Bleeding
Interventions: Device: Over-the-scope Clips; Device: Hemo-clipping; Device: thermo-coagulation; Drug: Epinephrine
Sponsors: Chinese University of Hong Kong; Queen Mary Hospital, Hong Kong; The First Affiliated Hospital of Soochow University; Beijing Friendship Hospital; Zhejiang University; Ningbo No. 1 Hospital
Recruiting -
Lu-177-DOTATATE (Lutathera) in Therapy of Inoperable Pheochromocytoma/ Paraganglioma
Posted: July 2nd, 2017, 2:00pm GMT
Conditions: Pheochromocytoma; Paraganglioma; Neuroendocrine Tumors; Neuroendocrine Neoplasms
Interventions: Drug: Lu-177-DOTATATE; Drug: Ga-68-DOTATATE; Drug: F-18-FDG; Drug: Amino Acid solution
Sponsor: National Cancer Institute (NCI)
Recruiting -
Preoperative Alpha Blockade for Pheochromocytoma
Posted: June 5th, 2017, 2:00pm GMT
Conditions: Pheochromocytoma; Paraganglioma
Interventions: Drug: Phenoxybenzamine; Drug: Doxazosin
Sponsor: University of California, Los Angeles
Recruiting -
A Phase II Trial of the DNA Methyl Transferase Inhibitor, Guadecitabine (SGI-110), in Children and Adults With Wild Type GIST,Pheochromocytoma and Paraganglioma Associated With Succinate Dehydrogenase Deficiency and HLRCC-associated Kidney Cancer
Posted: May 24th, 2017, 2:00pm GMT
Conditions: Paraganglioma; Gastrointestinal Stromal Tumors; Carcinoma, Renal Cell; Renal Neoplasms; Pheochromocytoma
Intervention: Drug: SGI-110 (guadecitabine)
Sponsor: National Cancer Institute (NCI)
Recruiting -
Propranolol Hydrochloride in Treating Patients With Prostate Cancer Undergoing Surgery
Posted: May 15th, 2017, 2:00pm GMT
Condition: Prostate Carcinoma
Interventions: Other: Laboratory Biomarker Analysis; Drug: Propranolol Hydrochloride; Other: Questionnaire Administration; Other: Survey Administration
Sponsors: Wake Forest University Health Sciences; National Cancer Institute (NCI)
Recruiting -
Surgery and Heated Intraperitoneal Chemotherapy for Adrenocortical Carcinoma
Posted: April 25th, 2017, 2:00pm GMT
Conditions: Adrenocortical Carcinoma; Peritoneal Carcinomatosis
Interventions: Drug: Cisplatin; Drug: Sodium thiosulfate; Procedure: Cytoreductive surgery
Sponsor: Columbia University
Recruiting -
Collection of Serum Samples in Studying Emotional Stress in Patients With Prostate Cancer
Posted: April 21st, 2017, 2:00pm GMT
Conditions: Hormone-Resistant Prostate Cancer; Recurrent Prostate Carcinoma; Stage I Prostate Cancer; Stage II Prostate Cancer; Stage IIA Prostate Cancer; Stage IIB Prostate Cancer
Interventions: Procedure: Biospecimen Collection; Other: Laboratory Biomarker Analysis; Other: Questionnaire Administration
Sponsors: Wake Forest University Health Sciences; National Cancer Institute (NCI)
Recruiting -
Nivolumab in Treating Patients With Localized Kidney Cancer Undergoing Nephrectomy
Posted: February 16th, 2017, 3:00pm GMT
Conditions: Metastatic Malignant Neoplasm in Lymph Node; Metastatic Malignant Neoplasm in the Adrenal Gland; Metastatic Malignant Neoplasm in the Lung; Metastatic Malignant Neoplasm in the Pancreas; Metastatic Malignant Neoplasm in the Skin; Metastatic Malignant Neoplasm in the Soft Tissues; Metastatic Renal Cell Carcinoma; Sarcomatoid Renal Cell Carcinoma; Stage II Renal Cell Cancer AJCC v7; Stage III Renal Cell Cancer AJCC v7; Unclassified Renal Cell Carcinoma
Interventions: Procedure: Conventional Surgery; Biological: Nivolumab; Other: Patient Observation; Other: Quality-of-Life Assessment; Other: Questionnaire Administration
Sponsors: National Cancer Institute (NCI); Canadian Cancer Trials Group
Recruiting -
Functional Magnetic Resonance Imaging in Assessing Affect Reactivity and Regulation in Patients With Stage 0-III Breast Cancer
Posted: February 13th, 2017, 3:00pm GMT
Conditions: Healthy Subject; Stage 0 Breast Cancer; Stage IA Breast Cancer; Stage IB Breast Cancer; Stage IIA Breast Cancer; Stage IIB Breast Cancer; Stage IIIA Breast Cancer; Stage IIIB Breast Cancer; Stage IIIC Breast Cancer
Interventions: Procedure: Biospecimen Collection; Procedure: Functional Magnetic Resonance Imaging; Other: Questionnaire Administration
Sponsors: Stanford University; National Cancer Institute (NCI)
Recruiting -
Comprehensive Data Collection and Follow-Up for Patients With Thyroid, Parathyroid and Adrenal Disease
Posted: February 13th, 2017, 3:00pm GMT
Condition: Endocrine Disease
Interventions: Other: Data Collection; Behavioral: Follow Up
Sponsor: M.D. Anderson Cancer Center
Recruiting -
Familial Investigations of Childhood Cancer Predisposition
Posted: February 10th, 2017, 3:00pm GMT
Conditions: Acute Leukemia; Adenomatous Polyposis; Adrenocortical Carcinoma; AML; BAP1 Tumor Predisposition Syndrome; Carney Complex; Choroid Plexus Carcinoma; Constitutional Mismatch Repair Deficiency Syndrome; Diamond-Blackfan Anemia; DICER1 Syndrome; Dyskeratosis Congenita; Emberger Syndrome; Familial Acute Myeloid Leukemia; Familial Adenomatous Polyposis; Fanconi Anemia; Familial Cancer; Familial Wilms Tumor; Familial Neuroblastoma; GIST; Hereditary Breast and Ovarian Cancer; Hereditary Paraganglioma-Pheochromocytoma Syndrome; Hodgkin Lymphoma; Juvenile Polyposis; Li-Fraumeni Syndrome; Lynch Syndrome; MDS; Melanoma Syndrome; Multiple Endocrine Neoplasia Type 1; Multiple Endocrine Neoplasia Type 2; Neuroblastoma; Neurofibromatosis Type 1; Neurofibromatosis Type II; Nevoid Basal Cell Carcinoma Syndrome; Non Hodgkin Lymphoma; Noonan Syndrome and Other Rasopathy; Overgrowth Syndromes; Pancreatic Cancer; Peutz-Jeghers Syndrome; Pheochromocytoma/Paraganglioma; PTEN Hamartoma Tumor Syndrome; Retinoblastoma; Rhabdoid Tumor Predisposition Syndrome; Rhabdomyosarcoma; Rothmund-Thomson Syndrome; Tuberous Sclerosis; Von Hippel-Lindau Disease
Intervention:
Sponsor: St. Jude Children's Research Hospital
Recruiting -
Study of Biomarker-Based Treatment of Acute Myeloid Leukemia
Posted: January 9th, 2017, 3:00pm GMT
Condition: Previously Untreated Acute Myeloid Leukemia
Interventions: Biological: Samalizumab (BAML-16-001-S1); Biological: BI 836858 (BAML-16-001-S2); Other: Laboratory Biomarker Analysis; Drug: Daunorubicin (BAML-16-001-S1); Drug: Cytarabine (BAML-16-001-S1); Drug: Azacitidine (BAML-16-001-S2); Drug: AG-221 (BAML-16-001-S3); Drug: Azacitidine (BAML-16-001-S3); Drug: Entospletinib (BAML-16-001-S4); Drug: Azacitidine (BAML-16-001-S4); Drug: Entospletinib (BAML-16-001-S5); Drug: Decitabine (BAML-16-001-S5); Drug: Entospletinib (BAML-16-001-S6); Drug: Azacitidine (BAML-16-001-S6); Drug: Daunorubicin (BAML-16-001-S6); Drug: Cytarabine (BAML-16-001-S6); Drug: Pevonedistat (BAML-16-001-S9); Drug: Azacitidine (BAML-16-001-S9); Drug: AG-120 (BAML-16-001-S16); Drug: Azacitidine (BAML-16-001-S16); Drug: Gilteritinib (BAML-16-001-S8); Drug: Decitabine (BAML-16-001-S8)
Sponsor: Beat AML, LLC
Recruiting -
Lenvatinib in Treating Patients With Metastatic or Advanced Pheochromocytoma or Paraganglioma That Cannot Be Removed by Surgery
Posted: January 2nd, 2017, 3:00pm GMT
Conditions: Malignant Adrenal Gland Pheochromocytoma; Malignant Paraganglioma; Metastatic Adrenal Gland Pheochromocytoma
Interventions: Other: Laboratory Biomarker Analysis; Drug: Lenvatinib; Other: Quality-of-Life Assessment
Sponsors: Mayo Clinic; National Cancer Institute (NCI)
Recruiting -
Cryobiopsy Versus Forceps Biopsy for Pulmonary Lesions
Posted: December 6th, 2016, 3:00pm GMT
Conditions: Solitary Pulmonary Nodule; Multiple Pulmonary Nodules
Intervention: Procedure: transbronchial biopsy
Sponsors: University of Pennsylvania; Andrew Haas; Anil Vachani; Anthony Lanfranco; Kevin Ma; Jeffrey Thompson; Edmund Moon
Recruiting -
PROstaTe Cancer - Exercise-STudy (PRO-TEST)
Posted: November 3rd, 2016, 2:00pm GMT
Condition: Prostate Cancer
Interventions: Behavioral: High Intensity Interval Training; Behavioral: Usual Care Observational Control
Sponsor: Rigshospitalet, Denmark
Recruiting -
The MATCH Study: Mindfulness And Tai Chi for Cancer Health
Posted: June 15th, 2016, 2:00pm GMT
Condition: Cancer
Interventions: Behavioral: Mindfulness Based Cancer Recovery (MBCR); Behavioral: Tai Chi/Qigong (TCQ) for Cancer Patients
Sponsors: Linda E. Carlson; University of Calgary; Alberta Health Services; Tom Baker Cancer Centre; Princess Margaret Hospital, Canada
Recruiting -
Evaluate Use of Caudal Nerve Blocks in Adult Penile Prosthesis
Posted: April 15th, 2016, 2:00pm GMT
Condition: Malignant Neoplasms of Male Genital Organs
Interventions: Procedure: Caudal Nerve Block (CNB); Drug: Ropivacaine; Drug: Epinephrine; Drug: Decadron; Drug: Clonidine; Drug: Propofol; Behavioral: Phone Call
Sponsors: M.D. Anderson Cancer Center; Merck Sharp & Dohme Corp.
Recruiting -
Pembrolizumab in Treating Patients With Rare Tumors That Cannot Be Removed by Surgery or Are Metastatic
Posted: March 29th, 2016, 2:00pm GMT
Conditions: Carcinoma of Unknown Primary Origin; Kidney Medullary Carcinoma; Malignant Germ Cell Tumor; Metastatic Adrenal Gland Pheochromocytoma; Metastatic Malignant Solid Neoplasm; Metastatic Paraganglioma; Metastatic Penile Carcinoma; Paraganglioma; Skin Squamous Cell Carcinoma; Small Cell Carcinoma; Stage IV Adrenal Cortex Carcinoma AJCC v7; Stage IV Penile Cancer AJCC v7; Stage IV Renal Cell Cancer AJCC v7; Unresectable Solid Neoplasm; Vascular Neoplasm
Interventions: Other: Laboratory Biomarker Analysis; Biological: Pembrolizumab; Other: Questionnaire Administration
Sponsors: M.D. Anderson Cancer Center; National Cancer Institute (NCI)
Recruiting -
Single Agent Pembrolizumab in Subjects With Advanced Adrenocortical Carcinoma
Posted: February 3rd, 2016, 3:00pm GMT
Condition: Adrenocortical Carcinoma
Intervention: Drug: Pembrolizumab
Sponsors: Memorial Sloan Kettering Cancer Center; Merck Sharp & Dohme Corp.
Recruiting -
A Dose-Escalation Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of IPI-549
Posted: December 22nd, 2015, 3:00pm GMT
Conditions: Advanced Solid Tumors (Part A/B/C/D); Non-small Cell Lung Cancer (Part E); Melanoma (Part E); Squamous Cell Cancer of the Head and Neck (Part E); Triple Negative Breast Cancer (Part F); Adrenocortical Carcinoma (Part G); Mesothelioma (Part G); High-circulating Myeloid-derived Suppressor Cells (Part H)
Interventions: Drug: IPI-549; Drug: Nivolumab
Sponsor: Infinity Pharmaceuticals, Inc.
Recruiting -
Exercise Intervention for LGBT Cancer Survivors
Posted: June 2nd, 2015, 2:00pm GMT
Condition: Neoplasms
Intervention: Behavioral: Exercise for Cancer Patients
Sponsor: University of Rochester
Recruiting -
The Effect of the Serratus Block on Pain Control After Breast Surgery
Posted: May 25th, 2015, 2:00pm GMT
Condition: Anesthesia
Interventions: Procedure: Serratus Block; Procedure: Placebo Block; Drug: ropivacaine; Drug: epinephrine; Other: sterile saline
Sponsor: Women's College Hospital
Recruiting -
USDA Western Human Nutrition Research Center (WHNRC) Cross-Sectional Nutritional Phenotyping Study
Posted: February 20th, 2015, 3:00pm GMT
Conditions: Obesity; Inflammation
Intervention:
Sponsor: USDA, Western Human Nutrition Research Center
Recruiting -
Structured Evaluation of adRENal Tumors Discovered Incidentally - Prospectively Investigating the Testing Yield
Posted: December 24th, 2014, 3:00pm GMT
Conditions: Adrenal Incidentaloma; Adrenocortical Carcinoma
Intervention:
Sponsors: University Medical Center Groningen; Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA); VU University Medical Center; Radboud University; Leiden University Medical Center; Maastricht University Medical Center; UMC Utrecht; Erasmus Medical Center; Martini Hospital Groningen; Canisius-Wilhelmina Hospital; Diakonessenhuis, Utrecht; Isala; Haga Hospital; St. Antonius Hospital; Kennemer Gasthuis; Maxima Medical Center; Medical Center Alkmaar; Medical Centre Leeuwarden; Meander Medical Center; Medisch Spectrum Twente; Onze Lieve Vrouwe Gasthuis; Rijnstate Hospital; Elisabeth-TweeSteden Ziekenhuis; Tergooi Hospital; Vlietland Ziekenhuis; Scheper Hospital; Flevo Hospital
Recruiting -
Study to Evaluate the Effects of Cabozantinib in Patients With Unresectable Metastatic Pheochromocytomas and Paragangliomas
Posted: November 27th, 2014, 3:00pm GMT
Conditions: Locally Advanced Paraganglioma; Metastatic Adrenal Gland Pheochromocytoma; Metastatic Paraganglioma; Regional Adrenal Gland Pheochromocytoma; Unresectable Adrenal Gland Pheochromocytoma; Unresectable Paraganglioma
Interventions: Drug: Cabozantinib S-malate; Other: Laboratory Biomarker Analysis; Other: Questionnaire Administration
Sponsors: M.D. Anderson Cancer Center; National Cancer Institute (NCI)
Recruiting -
Phase I/II Study of MEK162 for Children With Ras/Raf Pathway Activated Tumors
Posted: November 7th, 2014, 3:00pm GMT
Conditions: Low-Grade Gliomas; Malignant Neoplasms, Brain; Soft Tissue Neoplasms
Intervention: Drug: MEK162
Sponsors: Children's Hospital Los Angeles; Dana-Farber Cancer Institute
Recruiting -
Phase II Study of Proton Radiation Therapy for Neuroblastoma
Posted: April 14th, 2014, 2:00pm GMT
Conditions: Neuroblastoma; Ganglioneuroblastoma
Intervention: Radiation: Proton Beam Radiation Therapy
Sponsors: Massachusetts General Hospital; National Cancer Institute (NCI)
Recruiting -
Effect of Chronic Catecholamine Overproduction on Brown Adipose Tissue
Posted: September 24th, 2013, 2:00pm GMT
Conditions: Pheochromocytoma; Adrenal Incidentaloma
Intervention: Procedure: Removal of adrenal tumor
Sponsor: University of Aarhus
Recruiting -
A Phase IV Post Approval Clinical Study of ExAblate Treatment of Metastatic Bone Tumors for the Palliation of Pain
Posted: April 17th, 2013, 2:00pm GMT
Condition: Bone Metastasis
Intervention: Device: ExAblate MRgFUS
Sponsor: InSightec
Recruiting -
European Low and Intermediate Risk Neuroblastoma Protocol
Posted: November 16th, 2012, 3:00pm GMT
Condition: LOW AND INTERMEDIATE PAEDIATRIC NEUROBLASTOMA AND NEONATAL SUPRARENAL MASSES
Intervention: Drug: chemotherapy
Sponsor: Instituto de Investigacion Sanitaria La Fe
Recruiting -
Long-term Beneficial Metabolic Effects of Adrenalectomy in Subclinical Cushing's Syndrome of Adrenal Incidentaloma
Posted: June 27th, 2011, 2:00pm GMT
Condition: Cushing Syndrome
Intervention: Procedure: surgery
Sponsors: Samsung Medical Center; Asan Medical Center; Severance Hospital; Konkuk University Medical Center
Recruiting -
Androgen-Deprivation Therapy and Radiation Therapy in Treating Patients With Prostate Cancer
Posted: June 8th, 2011, 2:00pm GMT
Condition: Prostate Cancer
Interventions: Radiation: radiation therapy; Radiation: Whole-pelvic radiotherapy (WPRT)
Sponsors: Radiation Therapy Oncology Group; National Cancer Institute (NCI); NRG Oncology
Recruiting -
Adrenalectomy Versus Follow-up in Patients With Subclinical Cushings Syndrome
Posted: November 23rd, 2010, 3:00pm GMT
Condition: Adrenal Tumour With Mild Hypercortisolism
Intervention: Procedure: Adrenalectomy
Sponsor: Region Skane
Recruiting -
Prospective Comprehensive Molecular Analysis of Endocrine Neoplasms
Posted: November 2nd, 2009, 3:00pm GMT
Conditions: Endocrine Tumors; Thyroid Neoplasms; Parathyroid Neoplasms; Adrenal Neoplasm; Neuroblastoma
Intervention:
Sponsor: National Cancer Institute (NCI)
Recruiting -
International Pediatric Adrenocortical Tumor Registry
Posted: June 18th, 2008, 2:00pm GMT
Condition: Adrenocortical Tumor
Intervention:
Sponsor: St. Jude Children's Research Hospital
Recruiting -
Molecular Characterization of Neuroblastic Tumor: Correlation With Clinical Outcome
Posted: January 8th, 2008, 3:00pm GMT
Condition: Neuroblastoma
Intervention: Other: Tumor and Marrow Markers
Sponsors: Memorial Sloan Kettering Cancer Center; Southern Illinois University; Spanish National Cancer Center; St. Jude Children's Research Hospital; Washington University School of Medicine; University of Texas; Weill Medical College of Cornell University
Recruiting -
Study of Adrenal Gland Tumors
Posted: June 29th, 2000, 2:00pm GMT
Condition: Adrenal Gland Neoplasm
Intervention:
Sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Recruiting