Patients with pancreatic cancer often have elevated blood levels of CA19-9, a carbohydrate antigen present on many proteins. CA19-9 is thus commonly used ...
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The glycan CA19-9 promotes pancreatitis and pancreatic cancer in mice - Science Magazine
Posted: June 20th, 2019, 4:03pm GMT
The glycan CA19-9 promotes pancreatitis and pancreatic cancer in mice Science Magazine -
ARID1A spatially partitions interphase chromosomes - Science Advances
Posted: May 22nd, 2019, 5:00am GMT
ARID1A spatially partitions interphase chromosomes Science AdvancesARID1A, a subunit of the SWItch/Sucrose Non-Fermentable (SWI/SNF) chromatin-remodeling complex, localizes to both promoters and enhancers to influence ...
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ARID1A spatially partitions interphase chromosomes - Science Advances
Posted: May 22nd, 2019, 5:00am GMT
ARID1A spatially partitions interphase chromosomes Science AdvancesARID1A, a subunit of the SWItch/Sucrose Non-Fermentable (SWI/SNF) chromatin-remodeling complex, localizes to both promoters and enhancers to influence ...
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Protein that hinders advancement of prostate cancer identified - Medical Xpress
Posted: May 20th, 2019, 5:00am GMT
Protein that hinders advancement of prostate cancer identified Medical XpressResearchers at Boston University School of Medicine (BUSM) have discovered that blocking a specific protein, may be a promising strategy to prevent the ...
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Stage 4 pancreatic cancer survivor shares inspiring story - KTRK-TV
Posted: May 17th, 2019, 5:00am GMT
Stage 4 pancreatic cancer survivor shares inspiring story KTRK-TVAllison Kuban never expected to hear that she had pancreatic cancer after she suddenly began having stomach pains. But on her 31st birthday, her world was ...
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Kaplan USMLE Step 1 prep: Woman has excessive thirst, urination - American Medical Association
Posted: May 14th, 2019, 10:00am GMT
Kaplan USMLE Step 1 prep: Woman has excessive thirst, urination American Medical AssociationThe case: A 38-year-old woman has had excessive thirst and urination for four weeks. What cell is the pancreatic tumor from?
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New insights into treatment targets for men with advanced prostate cancers - Medical Xpress
Posted: May 13th, 2019, 5:00am GMT
New insights into treatment targets for men with advanced prostate cancers Medical XpressA study published recently in the Journal of Clinical Oncology Precision Oncology, an American Society of Clinical Oncology (ASCO) journal, outlines findings ...
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North York General study shows safest method for prostate cancer biopsies - Medical Xpress
Posted: May 9th, 2019, 5:00am GMT
North York General study shows safest method for prostate cancer biopsies Medical XpressThe Gale and Graham Wright Prostate Centre at North York General Hospital (NYGH) is advancing prostate cancer care with a new study that shows the benefits ...
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Men taking medications for enlarged prostate face delays in prostate cancer diagnosis - Medical Xpress
Posted: May 6th, 2019, 5:00am GMT
Men taking medications for enlarged prostate face delays in prostate cancer diagnosis Medical XpressMen treated with medications for symptoms of benign prostatic hyperplasia (BPH) experienced a two-year delay in diagnosis of their prostate cancer and were ...
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A new method to select the right treatment for advanced prostate cancer - Medical Xpress
Posted: May 3rd, 2019, 5:00am GMT
A new method to select the right treatment for advanced prostate cancer Medical XpressResearchers at Karolinska Institutet in Sweden have identified blood-based biomarkers that may determine which patients will benefit from continued hormonal ...
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Removal of gene prevents development of pancreatic cancer in mice - Medical Xpress
Posted: May 2nd, 2019, 5:00am GMT
Removal of gene prevents development of pancreatic cancer in mice Medical XpressThe action of a gene called ATDC is required for the development of pancreatic cancer, a new study finds.
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Deleting just one gene may 'completely prevent' pancreatic cancer - Medical News Today
Posted: May 2nd, 2019, 5:00am GMT
Deleting just one gene may 'completely prevent' pancreatic cancer Medical News TodayUsing a mouse model of pancreatic cancer, researchers have zoomed in on a single gene that stopped aggressive pancreatic cancer from developing when the ...
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Removal of gene completely prevents development of aggressive pancreatic cancer in mice - Science Daily
Posted: May 1st, 2019, 5:00am GMT
Removal of gene completely prevents development of aggressive pancreatic cancer in mice Science DailyThe action of a gene called ATDC is required for the development of pancreatic cancer, a new study finds.
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Single dose of targeted radiotherapy is safe and effective for prostate cancer - Medical Xpress
Posted: April 29th, 2019, 5:00am GMT
Single dose of targeted radiotherapy is safe and effective for prostate cancer Medical XpressA single high dose of radiation that can be delivered directly to the tumour within a few minutes is a safe and effective technique for treating men with low risk ...
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Feliciano Determines Which Patients Are Best Served by Either Immunotherapy or Targeted... - Targeted Oncology
Posted: April 25th, 2019, 11:18pm GMT
Feliciano Determines Which Patients Are Best Served by Either Immunotherapy or Targeted... Targeted OncologyDuring a Targeted Oncology live case-based peer perspectives presentation, Josephine Louella Feliciano, MD, explained the treatment considerations and ...
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Targeting LIF-mediated paracrine interaction for pancreatic cancer therapy and monitoring - Nature.com
Posted: April 17th, 2019, 3:03pm GMT
Targeting LIF-mediated paracrine interaction for pancreatic cancer therapy and monitoring Nature.comPancreatic ductal adenocarcinoma (PDAC) has a dismal prognosis largely owing to inefficient diagnosis and tenacious drug resistance. Activation of pancreatic ...
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Hydrogel microenvironments for cancer spheroid growth and drug screening - Science Advances
Posted: April 15th, 2019, 10:30pm GMT
Hydrogel microenvironments for cancer spheroid growth and drug screening Science AdvancesMulticellular cancer spheroids (MCSs) have emerged as a promising in vitro model that replicates many features of solid tumors in vivo. Biomimetic hydrogel ...
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New electron microscopy technique limits membrane destruction - Science Daily
Posted: April 10th, 2019, 5:00am GMT
New electron microscopy technique limits membrane destruction Science DailyResearchers have created an electron microscopy technique termed 'cryoAPEX' that accurately tracks membrane proteins in a well-preserved cell.
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Prostate cancer hormone therapy rejected on NHS in England - Medical Xpress
Posted: April 8th, 2019, 5:00am GMT
Prostate cancer hormone therapy rejected on NHS in England Medical XpressA prostate cancer drug won't be offered on the NHS any earlier in the treatment plans of patients living with the disease in England, after it failed to pass a ...
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Metastatic prostate cancer may have its own biomarker, research finds - Medical Xpress
Posted: April 2nd, 2019, 5:00am GMT
Metastatic prostate cancer may have its own biomarker, research finds Medical XpressProstate cancer can grow slowly and pose little threat to patients, or it can metastasize quickly, causing severe pain and death. But as of now, it's nearly ...
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Scientists identify compounds in coffee which may inhibit prostate cancer - Medical Xpress
Posted: March 18th, 2019, 5:00am GMT
Scientists identify compounds in coffee which may inhibit prostate cancer Medical XpressFor the first time, scientists have identified compounds found in coffee which may inhibit the growth of prostate cancer. This is a pilot study, carried out on ...
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Testosterone slows prostate cancer recurrence in low-risk patients - Medical Xpress
Posted: March 17th, 2019, 5:00am GMT
Testosterone slows prostate cancer recurrence in low-risk patients Medical XpressIn the largest such study so far undertaken, US researchers have shown that testosterone replacement slows the recurrence of prostate cancer in low-risk ...
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Scientists delineate pathway that helps us make antibodies - Science Daily
Posted: March 13th, 2019, 5:00am GMT
Scientists delineate pathway that helps us make antibodies Science DailyOur bodies are continuously concocting specific antibodies to thwart invaders like a virus or even pollen, and scientists have new information about how the ...
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Placental Findings and Effect of Prophylactic Hydrocortisone in Extremely Preterm Infants - AAP News
Posted: March 2nd, 2019, 11:01pm GMT
Placental Findings and Effect of Prophylactic Hydrocortisone in Extremely Preterm Infants AAP NewsOBJECTIVES: To investigate the relationship between histologic findings of the placenta and response to early postnatal hydrocortisone treatment used to ...
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How prostate cancer becomes treatment resistant - Medical Xpress
Posted: February 28th, 2019, 6:00am GMT
How prostate cancer becomes treatment resistant Medical XpressThe development of effective anti-androgen therapies for prostate cancer is a major scientific advance. However, some men who receive these targeted ...
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Phosphatidylinositol Biphosphate (PIP2) Signal Pathway - News-Medical.net
Posted: February 26th, 2019, 6:00am GMT
Phosphatidylinositol Biphosphate (PIP2) Signal Pathway News-Medical.netBy Jeyashree Sundaram, MBA. Phosphatidylinositol 4,5-bisphosphate (PIP2) is an essential lipid involved in metabolic processes. It is integral to the cell ...
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Immunotherapy combination generates responses against castration-resistant metastatic prostate cancer - Medical Xpress
Posted: February 15th, 2019, 6:00am GMT
Immunotherapy combination generates responses against castration-resistant metastatic prostate cancer Medical XpressSome patients with metastatic prostate cancer respond to a combination of immune checkpoint inhibitors after hormonal therapy and chemotherapy have failed, ...
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Shorter course of radiation therapy effective in treating men with prostate cancer - Medical Xpress
Posted: February 8th, 2019, 6:00am GMT
Shorter course of radiation therapy effective in treating men with prostate cancer Medical XpressA new UCLA-led study shows that men with low- or intermediate-risk prostate cancer can safely undergo higher doses of radiation over a significantly shorter ...
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Researchers develop prostate cancer prediction tool that has unmatched accuracy - Medical Xpress
Posted: February 7th, 2019, 6:00am GMT
Researchers develop prostate cancer prediction tool that has unmatched accuracy Medical XpressA team of researchers from the Icahn School of Medicine at Mount Sinai and Keck School of Medicine at the University of Southern California (USC) have ...
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Type 2 Diabetes GWAS Meta-Analysis in Japanese Population Identifies 28 Novel Risk Loci - GenomeWeb
Posted: February 4th, 2019, 6:00am GMT
Type 2 Diabetes GWAS Meta-Analysis in Japanese Population Identifies 28 Novel Risk Loci GenomeWebNEW YORK (GenomeWeb) – Researchers have uncovered more than two dozen new genetic loci that are linked to type 2 diabetes in the Japanese population.
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Inadequate support for sexual dysfunction in prostate cancer patients - Medical Xpress
Posted: February 4th, 2019, 6:00am GMT
Inadequate support for sexual dysfunction in prostate cancer patients Medical XpressMore than four in five men (81 percent) with prostate cancer struggle with poor sexual function following treatment for the disease, but over half (56 percent) fail ...
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Prostate cancer study shows promise for future treatment - Medical Xpress
Posted: February 4th, 2019, 6:00am GMT
Prostate cancer study shows promise for future treatment Medical XpressA new 'seek-and-destroy' gene therapeutic system could have the potential to treat prostate cancer in the future, after it halted the majority of tumours in ...
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Ibrutinib Combo Falls Short in Pancreatic Cancer - OncLive
Posted: January 22nd, 2019, 2:06pm GMT
Ibrutinib Combo Falls Short in Pancreatic Cancer OncLiveThe frontline combination of ibrutinib (Imbruvica) and nab-paclitaxel (Abraxane)/gemcitabine did not show a statistically significant benefit in progression-free or ...
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No Survival Improvement Seen With Ibrutinib Combination in Pancreatic Cancer - Targeted Oncology
Posted: January 22nd, 2019, 6:00am GMT
No Survival Improvement Seen With Ibrutinib Combination in Pancreatic Cancer Targeted OncologyFrontline treatment with ibrutinib plus nab-paclitaxel/gemcitabine did not have a statistically significant benefit in progression-free survival or overall survival ...
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Grantee Studies Cellular Changes to Stop Pancreatic Cancer Tumors - Pancreatic Cancer News & Stories
Posted: January 15th, 2019, 6:00am GMT
Grantee Studies Cellular Changes to Stop Pancreatic Cancer Tumors Pancreatic Cancer News & StoriesRecently published in Cancer Discovery, PanCAN grantee Kathryn Wellen, PhD, describes how blocking changes in cells' ability to break down nutrients could ...
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Scientists identify gene contributing to prostate cancer drug resistance - Medical Xpress
Posted: January 15th, 2019, 6:00am GMT
Scientists identify gene contributing to prostate cancer drug resistance Medical XpressResearchers have discovered how a gene involved in regulating hormone receptors may contribute to drug resistance in some prostate cancer patients.
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Surgery unnecessary for many prostate cancer patients - Medical Xpress
Posted: December 13th, 2018, 6:00am GMT
Surgery unnecessary for many prostate cancer patients Medical XpressOtherwise healthy men with advanced prostate cancer may benefit greatly from surgery, but many with this diagnosis have no need for it. These conclusions ...
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Researchers use computer model to predict prostate cancer progression - Medical Xpress
Posted: December 12th, 2018, 6:00am GMT
Researchers use computer model to predict prostate cancer progression Medical XpressAn international team of cancer researchers from Denmark and Germany have used cancer patient data to develop a computer model that can predict the ...
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Inflammatory bowel disease linked to prostate cancer - Medical Xpress
Posted: December 7th, 2018, 6:00am GMT
Inflammatory bowel disease linked to prostate cancer Medical XpressMen with inflammatory bowel disease have four to five times higher risk of being diagnosed with prostate cancer, reports a 20-year study from Northwestern ...
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Revolutionary technology pinpoints biopsies to detect prostate cancer - Medical Xpress
Posted: December 5th, 2018, 6:00am GMT
Revolutionary technology pinpoints biopsies to detect prostate cancer Medical XpressMedical software developed at UCL that overlays tumour information from MRI scans onto ultrasound images can help guide surgeons conducting biopsies and ...
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Pulling the genome apart: Chromosome segregation during mitosis explained - Phys.org
Posted: November 13th, 2018, 6:00am GMT
Pulling the genome apart: Chromosome segregation during mitosis explained Phys.orgWhen a cell divides—a process known as mitosis—its chromosomes need to be separated and evenly distributed into the newly created daughter cells.
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Dad-of-three given months to live after being struck down with an incurable form of cancer - WalesOnline
Posted: November 11th, 2018, 6:00am GMT
Dad-of-three given months to live after being struck down with an incurable form of cancer WalesOnlineMore than £30000 has been raised for Brian Farrell who wants to spend as much time as he can with his wife and children.
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Efficacy, effectiveness, and safety of herpes zoster vaccines in adults aged 50 and older: systematic review and network meta-analysis - The BMJ
Posted: October 25th, 2018, 5:00am GMT
Efficacy, effectiveness, and safety of herpes zoster vaccines in adults aged 50 and older: systematic review and network meta-analysis The BMJBMJ 2018; 363 doi: [https:] (Published 25 October 2018) Cite this as: BMJ 2018;363:k4029. Linked Editorial. Which shingles vaccine ...
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New kind of compound shows early promise against prostate cancer - Medical Xpress
Posted: October 23rd, 2018, 5:00am GMT
New kind of compound shows early promise against prostate cancer Medical XpressA new type of molecule blocks the action of genes that drive the growth of therapy-resistant prostate cancer, a new study finds.
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Cancer trial shows treating the prostate with radiotherapy improves survival - Medical Xpress
Posted: October 22nd, 2018, 5:00am GMT
Cancer trial shows treating the prostate with radiotherapy improves survival Medical XpressTreating the prostate with radiotherapy alongside standard treatment led to an 11 per cent increase in survival for some men with advanced prostate cancer, ...
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Rare Prostate Cancer Associated with Cushing’s Syndrome in Case Report - Cushing's Disease News
Posted: October 16th, 2018, 5:00am GMT
Rare Prostate Cancer Associated with Cushing’s Syndrome in Case Report Cushing's Disease NewsA patient with depression developed Cushing's syndrome (CS) because of a rare ACTH-secreting small cell cancer of the prostate, a case study reports.
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ALS drug may help treat prostate cancer - Medical Xpress
Posted: October 3rd, 2018, 5:00am GMT
ALS drug may help treat prostate cancer Medical XpressResearchers have discovered a new use for an old drug as a potential treatment for prostate cancer. The findings are published in the journal The Prostate.
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Early PSA testing could help predict prostate cancer among black men - Medical Xpress
Posted: October 2nd, 2018, 5:00am GMT
Early PSA testing could help predict prostate cancer among black men Medical XpressProstate cancer is the second most common cancer in American men. But black men bear a disproportionate burden of its effects. It's more common—and more ...
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Combo therapy of prostatectomy plus radiotherapy may improve survival in prostate cancer - Medical Xpress
Posted: September 25th, 2018, 5:00am GMT
Combo therapy of prostatectomy plus radiotherapy may improve survival in prostate cancer Medical XpressHigh-risk prostate cancer, that which has continued to grow but not yet metastasized, is commonly treated with combination therapies. Each method has pros ...
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Nanoparticle therapeutic restores function of tumor suppressor in prostate cancer - Medical Xpress
Posted: September 17th, 2018, 5:00am GMT
Nanoparticle therapeutic restores function of tumor suppressor in prostate cancer Medical XpressThink of it as a cancer therapy zag instead of a zig. While many groups are developing cancer therapies to target proteins and pathways that are highly active in ...
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Experts advise against routine testing for prostate cancer - Medical Xpress
Posted: September 5th, 2018, 5:00am GMT
Experts advise against routine testing for prostate cancer Medical XpressRoutine testing for prostate cancer is not recommended for most men because the benefit is small and uncertain and there are clear harms, say a panel of ...
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Immunotherapy could offer hope for some men with aggressive prostate cancers - Medical Xpress
Posted: September 5th, 2018, 5:00am GMT
Immunotherapy could offer hope for some men with aggressive prostate cancers Medical XpressA group of men with especially aggressive prostate cancer may respond unusually well to immunotherapy, a major new study reports.
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Inhibition of Histone Deacetylase Activity Aggravates Coxsackievirus B3-Induced Myocarditis by Promoting Viral Replication and Myocardial Apoptosis - Journal of Virology
Posted: August 28th, 2018, 11:00am GMT
Inhibition of Histone Deacetylase Activity Aggravates Coxsackievirus B3-Induced Myocarditis by Promoting Viral Replication and Myocardial Apoptosis Journal of VirologyViral myocarditis, which is most prevalently caused by coxsackievirus B3 (CVB3), is a serious clinical condition characterized by excessive myocardial ...
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Echovirus 7 Entry into Polarized Caco-2 Intestinal Epithelial Cells Involves Core Components of the Autophagy Machinery - Journal of Virology
Posted: August 23rd, 2018, 9:05pm GMT
Echovirus 7 Entry into Polarized Caco-2 Intestinal Epithelial Cells Involves Core Components of the Autophagy Machinery Journal of VirologyEchovirus 7 enters polarized Caco-2 intestinal epithelial cells by a clathrin-mediated endocytic process and then moves through the endosomal system before ...
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Phosphatidylinositol Biphosphate (PIP2) Signal Pathway - News-Medical.net
Posted: August 23rd, 2018, 5:00am GMT
Phosphatidylinositol Biphosphate (PIP2) Signal Pathway News-Medical.netBy Jeyashree Sundaram, MBA. Phosphatidylinositol 4,5-bisphosphate (PIP2) is an essential lipid involved in metabolic processes. It is integral to the cell ...
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Early-life alcohol intake may increase the odds of high-grade prostate cancer - Medical Xpress
Posted: August 23rd, 2018, 5:00am GMT
Early-life alcohol intake may increase the odds of high-grade prostate cancer Medical XpressCompared with non-drinkers, men who consumed at least seven drinks per week during adolescence (ages 15-19) had three times the odds of being diagnosed ...
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Microcalcifications in Breast Cancer - News-Medical.net
Posted: August 2nd, 2018, 1:21am GMT
Microcalcifications in Breast Cancer News-Medical.netCalcifications in the breast can be benign or malignant. They can appear as either macrocalcifications or microcalcifications on a mammogram (i.e. an X-ray of ...
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Microcalcifications in Breast Cancer - News-Medical.net
Posted: August 2nd, 2018, 1:21am GMT
Microcalcifications in Breast Cancer News-Medical.netCalcifications in the breast can be benign or malignant. They can appear as either macrocalcifications or microcalcifications on a mammogram (i.e. an X-ray of ...
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Discovering the mechanisms that underlie prostate cancer - Medical Xpress
Posted: July 12th, 2018, 5:00am GMT
Discovering the mechanisms that underlie prostate cancer Medical XpressNew research has uncovered insights into the mechanisms that underlie prostate cancer, providing potential targets for new cancer therapies.
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Deadly form of advanced prostate cancer is common, calls for distinct treatment - Medical Xpress
Posted: July 9th, 2018, 5:00am GMT
Deadly form of advanced prostate cancer is common, calls for distinct treatment Medical XpressA new study of prostate cancer in 202 men, whose cancers had spread and were resistant to standard treatment, found that a surprisingly large number of these ...
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EGFR+ NSCLC - Targeted Oncology
Posted: June 29th, 2018, 5:15pm GMT
EGFR+ NSCLC Targeted OncologyMark Socinski, MD, outlines the diagnosis and treatment of a 66-year-old Asian woman who presents with EGFR+ non-small cell lung cancer.
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Immunotherapy drug for skin disease could boost hormone treatment for prostate cancer - Medical Xpress
Posted: June 27th, 2018, 5:00am GMT
Immunotherapy drug for skin disease could boost hormone treatment for prostate cancer Medical XpressA new form of immunotherapy reactivates the response to hormone treatment in advanced prostate cancer, a study in mice and human prostate cancer cells has ...
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Acinic Cell Carcinoma - News-Medical.net
Posted: June 20th, 2018, 11:29pm GMT
Acinic Cell Carcinoma News-Medical.netAs salivary glands are made up of different cells, tumors could start in any one of such. Various salivary gland tumors, which may be benign or malignant, may ...
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Acinic Cell Carcinoma - News-Medical.net
Posted: June 20th, 2018, 11:29pm GMT
Acinic Cell Carcinoma News-Medical.netAs salivary glands are made up of different cells, tumors could start in any one of such. Various salivary gland tumors, which may be benign or malignant, may ...
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Fewer men are being screened, diagnosed, and treated for prostate cancer - Medical Xpress
Posted: May 21st, 2018, 5:00am GMT
Fewer men are being screened, diagnosed, and treated for prostate cancer Medical XpressA new study reveals declines in prostate cancer screening and diagnoses in the United States in recent years, as well as decreases in the use of definitive ...
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LI scientist paves the way for halting pancreatic cancer's spread - Newsday
Posted: May 17th, 2018, 5:00am GMT
LI scientist paves the way for halting pancreatic cancer's spread NewsdayOn Wednesday, Dr. Douglas Fearon, a scientist at Cold Spring Harbor Laboratory, discussed his discovery that dormant pancreatic cancer cells are lying in wait ...
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Bone scan software accurately calculates prognosis of advanced prostate cancer - Medical Xpress
Posted: May 17th, 2018, 5:00am GMT
Bone scan software accurately calculates prognosis of advanced prostate cancer Medical XpressA software tool to automatically calculate how extensively bones have been infiltrated by prostate cancer is both accurate and speedy, capturing key prognostic ...
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Initiation of ADT in a Man With Locally Advanced Prostate Cancer and Multiple Cardiovascular Risk Factors - Cancer Network
Posted: May 15th, 2018, 5:00am GMT
Initiation of ADT in a Man With Locally Advanced Prostate Cancer and Multiple Cardiovascular Risk Factors Cancer NetworkA 65-year-old man presented with locally advanced, high-risk prostate cancer. His medical history was remarkable for type 2 diabetes mellitus, and he was an ...
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Experts have new advice on prostate cancer screening. Here's why they put it back on the table - Medical Xpress
Posted: May 12th, 2018, 5:00am GMT
Experts have new advice on prostate cancer screening. Here's why they put it back on the table Medical XpressIn a shift that puts early detection of prostate cancer back on the agenda of middle-aged men and their doctors, a federal panel of experts is recommending that ...
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Scientists screen molecules for promise as new prostate cancer drugs - Medical Xpress
Posted: May 11th, 2018, 5:00am GMT
Scientists screen molecules for promise as new prostate cancer drugs Medical XpressCancer researchers at the University of Bath have measured systematically how efficient molecules are at suppressing the activity of a protein associated with ...
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Hydrogel microenvironments for cancer spheroid growth and drug screening - Science Advances
Posted: April 27th, 2018, 5:00am GMT
Hydrogel microenvironments for cancer spheroid growth and drug screening Science AdvancesMulticellular cancer spheroids (MCSs) have emerged as a promising in vitro model that replicates many features of solid tumors in vivo. Biomimetic hydrogel ...
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Hydrogel microenvironments for cancer spheroid growth and drug screening - Science Advances
Posted: April 27th, 2018, 5:00am GMT
Hydrogel microenvironments for cancer spheroid growth and drug screening Science AdvancesMulticellular cancer spheroids (MCSs) have emerged as a promising in vitro model that replicates many features of solid tumors in vivo. Biomimetic hydrogel ...
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Man-made antibodies show promise in attacking cancer cells in animal models - Medical Xpress
Posted: April 16th, 2018, 5:00am GMT
Man-made antibodies show promise in attacking cancer cells in animal models Medical XpressUsing chemotherapy along with aptamers—lab-made molecules that function like antibodies—Duke Health researchers showed that they can zero in on and kill ...
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EGFR+ Non-Small Cell Lung Cancer: Frontline Options - Targeted Oncology
Posted: April 13th, 2018, 5:00am GMT
EGFR+ Non-Small Cell Lung Cancer: Frontline Options Targeted OncologyMark Socinski, MD, shares insight on the frontline systemic therapy options available for EGFR-mutant NSCLC treatment and considers multidisciplinary care in ...
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EGFR+ NSCLC: Treatment Through Multiple Lines of Therapy - Targeted Oncology
Posted: April 13th, 2018, 5:00am GMT
EGFR+ NSCLC: Treatment Through Multiple Lines of Therapy Targeted OncologyMark Socinski, MD, discusses his recommendations if a patient with EGFR-mutant non-small cell lung cancer develops disease progression through multiple ...
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Approaching a Case of EGFR+ Non-Small Cell Lung Cancer - Targeted Oncology
Posted: April 13th, 2018, 5:00am GMT
Approaching a Case of EGFR+ Non-Small Cell Lung Cancer Targeted OncologyMark Socinski, MD, outlines the diagnosis and treatment of a 66-year-old Asian woman who presents with EGFR+ non-small cell lung cancer and reviews ...
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Injecting gene cocktail into mouse pancreas leads to humanlike tumors - Medical Xpress
Posted: April 5th, 2018, 5:00am GMT
Injecting gene cocktail into mouse pancreas leads to humanlike tumors Medical XpressNovel technology developed at UT Health San Antonio gives rise to mouse pancreatic tumors that have the same traits as human pancreatic cancer. A U.S. ...
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Metabolic profiling may determine aggressiveness, prognosis of prostate cancer - Medical Xpress
Posted: March 26th, 2018, 5:00am GMT
Metabolic profiling may determine aggressiveness, prognosis of prostate cancer Medical XpressA new approach to analyzing prostate gland tissue may help address a major challenge in treating prostate cancer - determining which tumors are unlikely to ...
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Researchers create a drug to extend the lives of men with prostate cancer - Medical Xpress
Posted: March 16th, 2018, 5:00am GMT
Researchers create a drug to extend the lives of men with prostate cancer Medical XpressFifteen years ago, Michael Jung was already an eminent scientist when his wife asked him a question that would change his career, and extend the lives of ...
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Higher doses of radiation don't improve survival in prostate cancer - Medical Xpress
Posted: March 15th, 2018, 5:00am GMT
Higher doses of radiation don't improve survival in prostate cancer Medical XpressA new study shows that higher doses of radiation do not improve survival for many patients with prostate cancer, compared with the standard radiation treatment.
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Skp2-dependent reactivation of AKT drives resistance to PI3K inhibitors - Science
Posted: March 13th, 2018, 5:00am GMT
Skp2-dependent reactivation of AKT drives resistance to PI3K inhibitors SciencePredicting how a tumor can adapt to a drug may help identify the patients most likely to respond as well as strategies to avoid resistance. Activation of the kinase ...
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TGF-β-induced EMT: mechanisms and implications for fibrotic lung disease - AJP-Lung Physiology (subscription)
Posted: March 13th, 2018, 1:52am GMT
TGF-β-induced EMT: mechanisms and implications for fibrotic lung disease AJP-Lung Physiology (subscription)Epithelial-mesenchymal transition (EMT), a process whereby fully differentiated epithelial cells undergo transition to a mesenchymal phenotype giving rise to ...
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Multiple-treatment approach improves survival rates in aggressive prostate cancer, study finds - Medical Xpress
Posted: March 7th, 2018, 6:00am GMT
Multiple-treatment approach improves survival rates in aggressive prostate cancer, study finds Medical XpressUCLA researchers have discovered that a combination of high doses of radiotherapy and hormonal therapy provides the best chance of decreasing the mortality ...
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One-off PSA screening for prostate cancer does not save lives - Medical Xpress
Posted: March 6th, 2018, 6:00am GMT
One-off PSA screening for prostate cancer does not save lives Medical XpressInviting men with no symptoms to a one-off PSA test for prostate cancer does not save lives according to results from the largest ever prostate cancer trial ...
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Could Cassava leaves and roots extract be the Magic cure for colon, prostate and bladder cancers? - Modern Ghana
Posted: March 2nd, 2018, 6:00am GMT
Could Cassava leaves and roots extract be the Magic cure for colon, prostate and bladder cancers? Modern GhanaGrowing up in my village called Suhum-Amanhia on the Koforidua road; I quite remembered we were told of the two main varieties of cassava: The one eatable ...
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Norwich man trying to raise £70,000 for rare cancer treatment | Health - Norfolk Eastern Daily Press
Posted: February 14th, 2018, 6:00am GMT
Norwich man trying to raise £70,000 for rare cancer treatment | Health Norfolk Eastern Daily PressDamion Burbank has been diagnosed with a rare form of cancer, the family are hoping to rasie money to pay for treatments abroad. Damion at home with his ...
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Negative Repeat Biopsy in PCa Active Surveillance a Positive Sign - Renal and Urology News
Posted: February 8th, 2018, 6:00am GMT
Negative Repeat Biopsy in PCa Active Surveillance a Positive Sign Renal and Urology NewsIn a study, a negative confirmatory prostate biopsy in prostate cancer patients on active surveillance predicts a lower risk of progressing to treatment.
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Could Cassava leaves and roots extract be the Magic cure for colon, prostate and bladder cancers? - Modern Ghana
Posted: February 3rd, 2018, 6:00am GMT
Could Cassava leaves and roots extract be the Magic cure for colon, prostate and bladder cancers? Modern GhanaGrowing up in my village called Suhum-Amanhia on the Koforidua road; I quite remembered we were told of the two main varieties of cassava: The one eatable ...
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New prostate cancer risk score could help guide screening decisions - Medical Xpress
Posted: January 10th, 2018, 6:00am GMT
New prostate cancer risk score could help guide screening decisions Medical XpressA new score for predicting a man's genetic risk of developing aggressive prostate cancer could help guide decisions about who to screen and when, say ...
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Recommendations for genetic counseling and genetic testing for hereditary prostate cancer - Medical Xpress
Posted: December 13th, 2017, 6:00am GMT
Recommendations for genetic counseling and genetic testing for hereditary prostate cancer Medical XpressTo date, there have been few recommendations to guide physicians about when to offer men genetic consultation for prostate cancer risk. Now, an international ...
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Cell-cell adhesion in lung endothelium - AJP-Lung Physiology (subscription)
Posted: December 9th, 2017, 1:18pm GMT
Cell-cell adhesion in lung endothelium AJP-Lung Physiology (subscription)Homotypic cell-cell adhesion is essential for tissue and organ development, remodeling, regeneration, and physiological function. Whereas a significant number ...
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Pancreatic cancer: specific protein promotes development of pancreatitis and tumours - Drug Target Review
Posted: December 6th, 2017, 6:00am GMT
Pancreatic cancer: specific protein promotes development of pancreatitis and tumours Drug Target ReviewA study has shown that disruption to cell autophagy is involved in the development of pancreatic cancer.
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Specific protein promotes development of pancreatitis and tumours - Medical Xpress
Posted: December 5th, 2017, 6:00am GMT
Specific protein promotes development of pancreatitis and tumours Medical XpressPancreatic cancer is one of the most aggressive forms of cancer and is currently very difficult to treat. However, the last few years have seen advances in the ...
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Cell death linked to tumor growth in prostate cancer patients - Medical Xpress
Posted: November 27th, 2017, 6:00am GMT
Cell death linked to tumor growth in prostate cancer patients Medical XpressThe goal of any cancer treatment is to kill tumor cells. Yet, one little understood paradox of certain cancers is that the body's natural process for removing dead ...
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Low testosterone levels linked to reduced risk of prostate cancer - Medical Xpress
Posted: November 6th, 2017, 6:00am GMT
Low testosterone levels linked to reduced risk of prostate cancer Medical XpressMen with unusually low amounts of testosterone in their blood are around 20% less likely to develop prostate cancer, according to new research presented at ...
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Fast Five Quiz: Prostate Cancer - Medscape
Posted: October 15th, 2017, 4:04am GMT
Fast Five Quiz: Prostate Cancer MedscapeProstate cancer is the most common noncutaneous cancer in men and is the second most common cause of cancer deaths. Do you know what to watch for and ...
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Targeted α-Therapy of Metastatic Castration-Resistant Prostate Cancer with 225Ac-PSMA-617: Dosimetry Estimate and Empiric Dose Finding - Journal of Nuclear Medicine
Posted: October 1st, 2017, 5:00am GMT
Targeted α-Therapy of Metastatic Castration-Resistant Prostate Cancer with 225Ac-PSMA-617: Dosimetry Estimate and Empiric Dose Finding Journal of Nuclear Medicine+ Author Affiliations. 1Department of Nuclear Medicine, University Hospital Heidelberg, Heidelberg, Germany. 2Directorate for Nuclear Safety and Security, ...
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A versatile 3D tissue matrix scaffold system for tumor modeling and drug screening - Science Advances
Posted: September 13th, 2017, 5:00am GMT
A versatile 3D tissue matrix scaffold system for tumor modeling and drug screening Science AdvancesMost of the anticancer drug candidates entering preclinical trials fail to be approved for clinical applications. The following are among the main causes of these ...
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Functional Optical Imaging of Primary Human Tumor Organoids: Development of a Personalized Drug Screen - Journal of Nuclear Medicine
Posted: September 1st, 2017, 5:00am GMT
Functional Optical Imaging of Primary Human Tumor Organoids: Development of a Personalized Drug Screen Journal of Nuclear Medicine+ Author Affiliations. 1Department of Biomedical Engineering, Vanderbilt University, Nashville, Tennessee. 2Department of Cancer Biology, Vanderbilt University ...
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Androgen deprivation therapy increases risk of heart failure in men with prostate cancer - Medical Xpress
Posted: August 24th, 2017, 5:00am GMT
Androgen deprivation therapy increases risk of heart failure in men with prostate cancer Medical XpressMen with localized prostate cancer who received androgen deprivation therapy, a hormone treatment, were at significantly higher risk of heart failure than men ...
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