Conditions: Cholangiocarcinoma; Gallbladder Cancer
Intervention: Drug: Gemcitabine + Carboplatin
Sponsor: Washington University School of Medicine
Completed - verified May 2008
By Cancer
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Bile Duct Cancer
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(279)
ClinicalTrials.gov (183 unread)
Trial - Cholangiocarcinoma
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A Phase II Study of Gemcitabine and Carboplatin in the Treatment of Metastatic or Recurrent Cholangiocarcinoma/Gallbladder Cancer
Posted: April 11th, 2008, 10:00am EDT
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A Feasibility Phase II Study in the Treatment of Resected Cholangiocarcinoma, Gallbladder, Pancreatic and Ampullary Cancers
Posted: April 11th, 2008, 10:00am EDT
Conditions: Cholangiocarcinoma Cancer; Gallbladder Cancer; Pancreatic Cancer; Ampullary Cancer
Interventions: Drug: Gemcitabine and Docetaxel (Chemotherapy); Radiation: XRT at 5040 or 5400 cGy and 5FU (Radiation and Chemotherapy); Drug: Gemcitabine and Docetaxel (Chemotherapy)
Sponsor: Washington University School of Medicine
Recruiting - verified April 2008 -
Unilateral Versus Bilateral Stents for Bismuth Type II and III Malignant Hilar Strictures
Posted: April 2nd, 2008, 10:00am EDT
Condition: Cholangiocarcinoma
Intervention: Procedure: Endoscopic Retrograde Cholangiopancreatography (ERCP)
Sponsor: Changhai Hospital
Not yet recruiting - verified March 2008 -
Cyberknife Radiosurgery Boost for Hilar Cholangiocarcinoma (Klatskin Tumor)
Posted: February 28th, 2008, 10:00am EST
Conditions: Cholangiocarcinoma; Klatskin Tumor; Biliary Tract Cancer
Intervention: Radiation: External beam radiation and Cyberknife radiosurgery boost and capecitabine
Sponsor: University of California, San Francisco
Recruiting - verified February 2008
Trial - Bile Duct Cancer
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Gemcitabine With or Without Capecitabine in Treating Patients With Locally Advanced, Unresectable, or Metastatic Biliary Cancer
Posted: April 12th, 2008, 10:00am EDT
Conditions: Extrahepatic Bile Duct Cancer; Gallbladder Cancer; Liver Cancer
Interventions: Drug: capecitabine; Drug: gemcitabine hydrochloride; Procedure: oral chemotherapy; Procedure: parenteral chemotherapy; Procedure: quality-of-life assessment
Sponsors: National Cancer Institute of Canada; National Cancer Institute (NCI)
Not yet recruiting - verified April 2008 -
CBT-1 and Paclitaxel in Treating Patients With Refractory, Recurrent, or Advanced Metastatic Solid Tumors
Posted: April 12th, 2008, 10:00am EDT
Condition: Cancer
Interventions: Drug: MDR modulator CBT-1; Drug: paclitaxel; Drug: technetium 99m sestamibi; Procedure: chemosensitization/potentiation therapy; Procedure: drug resistance inhibition treatment; Procedure: parenteral chemotherapy; Procedure: radionuclide imaging
Sponsor: National Cancer Institute (NCI)
Recruiting - verified April 2008 -
Irinotecan, Fluorouracil, and Leucovorin in Treating Patients With Advanced Gastrointestinal Cancer
Posted: April 4th, 2008, 10:00am EDT
Conditions: Anal Cancer; Carcinoma of the Appendix; Colorectal Cancer; Esophageal Cancer; Extrahepatic Bile Duct Cancer; Gallbladder Cancer; Gastric Cancer; Gastrointestinal Carcinoid Tumor; Gastrointestinal Stromal Tumor; Liver Cancer; Pancreatic Cancer; Small Intestine Cancer
Interventions: Drug: fluorouracil; Drug: irinotecan hydrochloride; Drug: leucovorin calcium; Procedure: parenteral chemotherapy; Procedure: pharmacogenomic studies; Procedure: pharmacological study
Sponsors: Mayo Clinic; National Cancer Institute (NCI)
Not yet recruiting - verified April 2008 -
Randomized Controlled Trial on the Evaluation of Pylorus-Ring in Pancreaticoduodenectomy
Posted: March 14th, 2008, 10:00am EDT
Conditions: Pancreatic Cancer; Bile Duct Cancer; Ampullary Cancer; Duodenal Cancer; Pancreatitis
Interventions: Procedure: pylorus-preserving pancreaticoduodenectomy; Procedure: pylorus-resecting pancreaticoduodenectomy
Sponsor: Wakayama Medical University
Recruiting - verified March 2008 -
CO07204-Phase I/II of Oxaliplatin, Capecitabine & Sorafenib for Advanced Pancreatic & Biliary Carcinoma
Posted: March 5th, 2008, 10:00am EST
Conditions: Pancreatic Neoplasms; Bile Duct Neoplasms
Interventions: Drug: Oxaliplatin; Drug: Capecitabine; Drug: Sorafenib
Sponsors: University of Wisconsin, Madison; Bayer Health Care Pharmaceuticals; Sanofi-Aventis
Recruiting - verified March 2008 -
Gemcitabine With Peptide Vaccine Therapy in Treating Patients With Bile Duct Cancer
Posted: February 19th, 2008, 10:00am EST
Condition: Bile Duct Cancer
Intervention: Biological: Peptide vaccine for URLC10 and gemcitabine
Sponsors: Akita University Hospital; Human Genome Center, Institute of Medical Science, University of Tokyo
Recruiting - verified February 2008
Trial - Ampullary Carcinoma
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A Feasibility Phase II Study in the Treatment of Resected Cholangiocarcinoma, Gallbladder, Pancreatic and Ampullary Cancers
Posted: April 11th, 2008, 10:00am EDT
Conditions: Cholangiocarcinoma Cancer; Gallbladder Cancer; Pancreatic Cancer; Ampullary Cancer
Interventions: Drug: Gemcitabine and Docetaxel (Chemotherapy); Radiation: XRT at 5040 or 5400 cGy and 5FU (Radiation and Chemotherapy); Drug: Gemcitabine and Docetaxel (Chemotherapy)
Sponsor: Washington University School of Medicine
Recruiting - verified April 2008
Trial - Anal Cancers
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Pilot Study to Determine the Safety and Efficacy of Gardasil Against the Human Papilloma Virus (HPV) in HIV-Infected Men
Posted: April 22nd, 2008, 10:00am EDT
Conditions: Anal Cancer; HIV Infections
Intervention: Biological: Gardasil
Sponsors: Southern California Institute for Research and Education; Merck
Not yet recruiting - verified April 2008 -
CBT-1 and Paclitaxel in Treating Patients With Refractory, Recurrent, or Advanced Metastatic Solid Tumors
Posted: April 12th, 2008, 10:00am EDT
Condition: Cancer
Interventions: Drug: MDR modulator CBT-1; Drug: paclitaxel; Drug: technetium 99m sestamibi; Procedure: chemosensitization/potentiation therapy; Procedure: drug resistance inhibition treatment; Procedure: parenteral chemotherapy; Procedure: radionuclide imaging
Sponsor: National Cancer Institute (NCI)
Recruiting - verified April 2008 -
Irinotecan, Fluorouracil, and Leucovorin in Treating Patients With Advanced Gastrointestinal Cancer
Posted: April 4th, 2008, 10:00am EDT
Conditions: Anal Cancer; Carcinoma of the Appendix; Colorectal Cancer; Esophageal Cancer; Extrahepatic Bile Duct Cancer; Gallbladder Cancer; Gastric Cancer; Gastrointestinal Carcinoid Tumor; Gastrointestinal Stromal Tumor; Liver Cancer; Pancreatic Cancer; Small Intestine Cancer
Interventions: Drug: fluorouracil; Drug: irinotecan hydrochloride; Drug: leucovorin calcium; Procedure: parenteral chemotherapy; Procedure: pharmacogenomic studies; Procedure: pharmacological study
Sponsors: Mayo Clinic; National Cancer Institute (NCI)
Not yet recruiting - verified April 2008 -
Improving Bowel Preparation for Colonoscopy With a Simple Educational Card
Posted: March 20th, 2008, 10:00am EDT
Conditions: Colonic Polyps; Colonic Neoplasms
Intervention: Other: Educational card
Sponsor: Boston Medical Center
Recruiting - verified March 2008 -
External-Beam Radiation Therapy With or Without Indinavir and Ritonavir in Treating Patients With Brain Metastases
Posted: March 14th, 2008, 10:00am EDT
Condition: Cancer
Interventions: Drug: indinavir sulfate; Drug: ritonavir; Procedure: antiangiogenesis therapy; Procedure: drug modulation therapy; Procedure: enzyme inhibitor therapy; Procedure: radiation therapy; Procedure: radiosensitization
Sponsor: Oncology Institute of Southern Switzerland - Lugano
Recruiting - verified March 2008 -
Early Reversal of Defunctioning Stoma Trial
Posted: March 10th, 2008, 10:00am EDT
Condition: Rectal Cancer
Intervention: Procedure: Reversal of defunctioning stoma
Sponsor: Rectal Cancer Trial on Defunctioning Stoma Study Group
Recruiting - verified March 2008 -
Phase II Trial to Evaluate Laparoscopic Surgery for Stage 0/I Rectal Carcinoma
Posted: March 6th, 2008, 10:00am EST
Condition: Rectal Cancer
Intervention: Procedure: laparoscopic surgery for rectal carcinoma
Sponsor: Japan Society of Laparoscopic Colorectal Surgery
Recruiting - verified March 2008
Trial - Rhabdomyosarcoma
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Evaluating Dactinomycin and Vincristine in Young Patients With Cancer
Posted: May 6th, 2008, 10:00am EDT
Conditions: Kidney Cancer; Leukemia; Sarcoma; Unspecified Childhood Solid Tumor, Protocol Specific
Interventions: Drug: dactinomycin; Drug: vincristine; Procedure: chemotherapy; Procedure: diagnostic procedure; Procedure: liquid chromatography; Procedure: mass spectrometry; Procedure: pharmacological study; Procedure: polymerase chain reaction; Procedure: polymorphism analysis
Sponsors: Children's Oncology Group; National Cancer Institute (NCI)
Recruiting - verified April 2008 -
A Five-Tier, Phase 2 Open-Label Study of IMC-A12 Administered as a Single Agent
Posted: April 25th, 2008, 10:00am EDT
Conditions: Ewing's Sarcoma / Peripheral Neuroectodermal Tumor (PNET); Rhabdomyosarcoma; Leiomyosarcoma; Adipocytic Sarcoma; Synovial Sarcoma
Intervention: Biological: IMC-A12
Sponsor: ImClone Systems
Recruiting - verified April 2008 -
Combination Chemotherapy in Treating Patients With Sarcoma
Posted: April 18th, 2008, 10:00am EDT
Conditions: Ovarian Cancer; Sarcoma
Interventions: Drug: cyclophosphamide; Drug: doxorubicin hydrochloride; Drug: etoposide; Drug: ifosfamide; Drug: vincristine; Procedure: adjuvant therapy; Procedure: brachytherapy; Procedure: intraoperative radiation therapy; Procedure: neoadjuvant therapy; Procedure: parenteral chemotherapy; Procedure: radiation therapy; Procedure: therapeutic conventional surgery
Sponsors: Mayo Clinic; National Cancer Institute (NCI)
Active, not recruiting - verified April 2008 -
AZD0530 in Treating Patients With Recurrent Locally Advanced or Metastatic Soft Tissue Sarcoma
Posted: April 15th, 2008, 10:00am EDT
Condition: Sarcoma
Interventions: Drug: AZD0530; Procedure: protein tyrosine kinase inhibitor therapy
Sponsors: Princess Margaret Hospital, Canada; National Cancer Institute (NCI)
Recruiting - verified April 2008 -
Montelukast in Treating Patients With Bronchiolitis Obliterans After Donor Stem Cell Transplant
Posted: April 9th, 2008, 10:00am EDT
Condition: Cancer
Interventions: Drug: montelukast sodium; Procedure: flow cytometry; Procedure: laboratory biomarker analysis; Procedure: management of therapy complications; Procedure: pulmonary complications management; Procedure: quality-of-life assessment
Sponsor: National Cancer Institute (NCI)
Recruiting - verified May 2008 -
A Study of Avastin (Bevacizumab) in Combination With Standard Chemotherapy in Children and Adolescents With Sarcoma.
Posted: March 20th, 2008, 10:00am EDT
Condition: Sarcoma
Interventions: Drug: bevacizumab [Avastin]; Drug: Standard chemotherapy
Sponsor: Hoffmann-La Roche
Not yet recruiting - verified April 2008 -
A Study of R1507 in Patients With Recurrent or Refractory Sarcoma.
Posted: March 19th, 2008, 10:00am EDT
Condition: Sarcoma
Intervention: Drug: R1507
Sponsors: Hoffmann-La Roche; Sarcoma Alliance for Research through Collaboration
Recruiting - verified April 2008 -
Busulfan, Melphalan, Topotecan, and a Stem Cell Transplant in Treating Patients With Newly Diagnosed or Relapsed Solid Tumor
Posted: March 18th, 2008, 10:00am EDT
Conditions: Brain and Central Nervous System Tumors; Childhood Germ Cell Tumor; Extragonadal Germ Cell Tumor; Kidney Cancer; Neuroblastoma; Ovarian Cancer; Sarcoma; Testicular Germ Cell Tumor; Unspecified Adult Solid Tumor, Protocol Specific; Unspecified Childhood Solid Tumor, Protocol Specific
Interventions: Drug: busulfan; Drug: filgrastim; Drug: melphalan; Drug: topotecan hydrochloride; Procedure: autologous bone marrow transplantation; Procedure: autologous hematopoietic stem cell transplantation; Procedure: hematopoietic stem cell mobilization; Procedure: high-dose chemotherapy; Procedure: pharmacological study
Sponsors: Beckman Research Institute; National Cancer Institute (NCI)
Recruiting - verified March 2008 -
Rituximab in Treating Acute Graft-Versus-Host Disease in Patients Who Have Undergone a Donor Stem Cell Transplant
Posted: February 27th, 2008, 10:00am EST
Condition: Cancer
Interventions: Drug: cyclosporine; Drug: methylprednisolone; Drug: prednisone; Drug: rituximab; Drug: tacrolimus; Procedure: graft versus host disease prophylaxis/therapy; Procedure: monoclonal antibody therapy; Procedure: steroid therapy
Sponsor: Baylor College of Medicine
Recruiting - verified April 2008 -
Bone Marrow Radiation Therapy Followed by Busulfan, Melphalan, Thiotepa, and an Autologous Stem Cell Transplant in Treating Patients With High-Risk or Relapsed Solid Tumors
Posted: February 22nd, 2008, 10:00am EST
Conditions: Brain and Central Nervous System Tumors; Kidney Cancer; Liver Cancer; Retinoblastoma; Sarcoma; Unspecified Adult Solid Tumor, Protocol Specific; Unspecified Childhood Solid Tumor, Protocol Specific
Interventions: Drug: busulfan; Drug: etoposide; Drug: filgrastim; Drug: ifosfamide; Drug: melphalan; Drug: sargramostim; Drug: thiotepa; Procedure: autologous bone marrow transplantation; Procedure: autologous hematopoietic stem cell transplantation; Procedure: colony-stimulating factor therapy; Procedure: hematologic toxicity attenuation; Procedure: high-dose chemotherapy; Procedure: intensity-modulated radiation therapy; Procedure: peripheral blood stem cell transplantation; Procedure: pharmacological study; Procedure: positron emission tomography; Procedure: systemic chemotherapy; Procedure: tomotherapy; Procedure: total marrow irradiation
Sponsors: Masonic Cancer Center at University of Minnesota; National Cancer Institute (NCI)
Recruiting - verified February 2008
Trial - Adrenocortical Carcinoma
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Adrenal Tumors - Pathogenesis and Therapy
Posted: April 28th, 2008, 10:00am EDT
Conditions: Adrenal Tumors; Adrenocortical Carcinoma; Cushing Syndrome; Conn Syndrome; Pheochromocytoma
Intervention:
Sponsors: University of Wuerzburg; Deutsche Krebshilfe e.V., Bonn (Germany); Bundesministerium für Bildung und Forschung (BMBF)
Recruiting - verified April 2008 -
External-Beam Radiation Therapy With or Without Indinavir and Ritonavir in Treating Patients With Brain Metastases
Posted: March 14th, 2008, 10:00am EDT
Condition: Cancer
Interventions: Drug: indinavir sulfate; Drug: ritonavir; Procedure: antiangiogenesis therapy; Procedure: drug modulation therapy; Procedure: enzyme inhibitor therapy; Procedure: radiation therapy; Procedure: radiosensitization
Sponsor: Oncology Institute of Southern Switzerland - Lugano
Recruiting - verified March 2008
Trial - Adrenal Cancer
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Adrenal Tumors - Pathogenesis and Therapy
Posted: April 28th, 2008, 10:00am EDT
Conditions: Adrenal Tumors; Adrenocortical Carcinoma; Cushing Syndrome; Conn Syndrome; Pheochromocytoma
Intervention:
Sponsors: University of Wuerzburg; Deutsche Krebshilfe e.V., Bonn (Germany); Bundesministerium für Bildung und Forschung (BMBF)
Recruiting - verified April 2008 -
Metabolic Effect of Metformin in Obese Insulin Resistant Adolescents With Normal Glucose Tolerance
Posted: April 24th, 2008, 10:00am EDT
Conditions: Pediatric Obesity; Insulin Resistance; Hyperinsulinemia
Interventions: Drug: Metformin; Drug: Placebo
Sponsors: Yale University; National Institutes of Health (NIH)
Active, not recruiting - verified April 2008 -
Measuring Stress in Women With Newly Diagnosed Stage I, Stage II, or Stage III Breast Cancer or Ductal Carcinoma In Situ of the Breast
Posted: April 23rd, 2008, 10:00am EDT
Conditions: Anxiety Disorder; Breast Cancer; Depression; Psychosocial Effects/Treatment
Interventions: Procedure: assessment of therapy complications; Procedure: laboratory biomarker analysis; Procedure: psychosocial assessment and care; Procedure: questionnaire administration; Procedure: study of socioeconomic and demographic variables; Procedure: therapeutic conventional surgery
Sponsors: Wake Forest University; National Cancer Institute (NCI)
Recruiting - verified May 2008 -
Comparison of Paravertebral Block With General Anesthesia in Patients Undergoing Breast Cancer Surgery
Posted: March 19th, 2008, 10:00am EDT
Condition: Breast Cancer
Interventions: Procedure: Paravertebral Block; Procedure: General Anesthesia
Sponsor: Weill Medical College of Cornell University
Recruiting - verified April 2008
Trial - Adenoid Cystic Carcinoma
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CBT-1 and Paclitaxel in Treating Patients With Refractory, Recurrent, or Advanced Metastatic Solid Tumors
Posted: April 12th, 2008, 10:00am EDT
Condition: Cancer
Interventions: Drug: MDR modulator CBT-1; Drug: paclitaxel; Drug: technetium 99m sestamibi; Procedure: chemosensitization/potentiation therapy; Procedure: drug resistance inhibition treatment; Procedure: parenteral chemotherapy; Procedure: radionuclide imaging
Sponsor: National Cancer Institute (NCI)
Recruiting - verified April 2008 -
External-Beam Radiation Therapy With or Without Indinavir and Ritonavir in Treating Patients With Brain Metastases
Posted: March 14th, 2008, 10:00am EDT
Condition: Cancer
Interventions: Drug: indinavir sulfate; Drug: ritonavir; Procedure: antiangiogenesis therapy; Procedure: drug modulation therapy; Procedure: enzyme inhibitor therapy; Procedure: radiation therapy; Procedure: radiosensitization
Sponsor: Oncology Institute of Southern Switzerland - Lugano
Recruiting - verified March 2008 -
Bortezomib and Cetuximab in Treating Patients With Advanced Solid Tumors
Posted: February 22nd, 2008, 10:00am EST
Conditions: Breast Cancer; Colorectal Cancer; Head and Neck Cancer; Kidney Cancer; Lung Cancer; Pancreatic Cancer; Sarcoma; Unspecified Adult Solid Tumor, Protocol Specific
Interventions: Drug: bortezomib; Drug: cetuximab; Procedure: enzyme inhibitor therapy; Procedure: monoclonal antibody therapy
Sponsors: Masonic Cancer Center at University of Minnesota; National Cancer Institute (NCI)
Active, not recruiting - verified March 2008 -
Bortezomib and Gemcitabine in Treating Older Patients With Advanced Solid Tumors
Posted: February 20th, 2008, 10:00am EST
Conditions: Breast Cancer; Colorectal Cancer; Head and Neck Cancer; Kidney Cancer; Lung Cancer; Ovarian Cancer; Pancreatic Cancer; Prostate Cancer; Sarcoma; Small Intestine Cancer; Unspecified Adult Solid Tumor, Protocol Specific
Interventions: Drug: bortezomib; Drug: gemcitabine hydrochloride; Procedure: antiangiogenesis therapy; Procedure: chemotherapy; Procedure: enzyme inhibitor therapy; Procedure: pharmacological study
Sponsors: Masonic Cancer Center at University of Minnesota; National Cancer Institute (NCI)
Recruiting - verified March 2008
Trial - Sarcoma
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Evaluating Dactinomycin and Vincristine in Young Patients With Cancer
Posted: May 6th, 2008, 10:00am EDT
Conditions: Kidney Cancer; Leukemia; Sarcoma; Unspecified Childhood Solid Tumor, Protocol Specific
Interventions: Drug: dactinomycin; Drug: vincristine; Procedure: chemotherapy; Procedure: diagnostic procedure; Procedure: liquid chromatography; Procedure: mass spectrometry; Procedure: pharmacological study; Procedure: polymerase chain reaction; Procedure: polymorphism analysis
Sponsors: Children's Oncology Group; National Cancer Institute (NCI)
Recruiting - verified April 2008 -
Doxorubicin With Cisplatin, High-Dose Methotrexate, and Additional Risk-Adapted Outpatient Chemotherapy
Posted: May 6th, 2008, 10:00am EDT
Condition: Osteosarcoma
Interventions: Drug: Doxorubicin; Drug: Cisplatin; Drug: Methotrexate; Drug: Leucovorin; Drug: Dexrazoxane; Drug: Ifosfamide; Behavioral: Questionnaire; Drug: Gemcitabine; Drug: Sargramostim
Sponsor: M.D. Anderson Cancer Center
Recruiting - verified May 2008 -
A Five-Tier, Phase 2 Open-Label Study of IMC-A12 Administered as a Single Agent
Posted: April 25th, 2008, 10:00am EDT
Conditions: Ewing's Sarcoma / Peripheral Neuroectodermal Tumor (PNET); Rhabdomyosarcoma; Leiomyosarcoma; Adipocytic Sarcoma; Synovial Sarcoma
Intervention: Biological: IMC-A12
Sponsor: ImClone Systems
Recruiting - verified April 2008 -
A Study of Bevacizumab in Combination With Chemotherapy for Treatment of Osteosarcoma
Posted: April 24th, 2008, 10:00am EDT
Conditions: Osteosarcoma; Malignant Fibrous Histiocytoma (MFH) of Bone
Interventions: Biological: Bevacizumab; Drug: Chemotherapy (Cisplatin, Doxorubicin, Methotrexate); Drug: Chemotherapy (Cisplatin, Doxorubicin, Methotrexate, Ifosfamide, Etoposide)
Sponsors: St. Jude Children's Research Hospital; Genentech; National Institutes of Health (NIH)
Not yet recruiting - verified May 2008 -
AG014699 in Treating Patients With Locally Advanced or Metastatic Breast Cancer or Advanced Ovarian Cancer
Posted: April 22nd, 2008, 10:00am EDT
Conditions: Breast Cancer; Ovarian Cancer
Interventions: Drug: PARP-1 inhibitor AG014699; Procedure: enzyme inhibitor therapy; Procedure: immunohistochemistry staining method; Procedure: liquid chromatography; Procedure: mass spectrometry; Procedure: pharmacological study; Procedure: protein expression analysis; Procedure: western blotting
Sponsor: Cancer Research UK
Recruiting - verified April 2008 -
Combination Chemotherapy in Treating Patients With Sarcoma
Posted: April 18th, 2008, 10:00am EDT
Conditions: Ovarian Cancer; Sarcoma
Interventions: Drug: cyclophosphamide; Drug: doxorubicin hydrochloride; Drug: etoposide; Drug: ifosfamide; Drug: vincristine; Procedure: adjuvant therapy; Procedure: brachytherapy; Procedure: intraoperative radiation therapy; Procedure: neoadjuvant therapy; Procedure: parenteral chemotherapy; Procedure: radiation therapy; Procedure: therapeutic conventional surgery
Sponsors: Mayo Clinic; National Cancer Institute (NCI)
Active, not recruiting - verified April 2008 -
AZD0530 in Treating Patients With Recurrent Locally Advanced or Metastatic Soft Tissue Sarcoma
Posted: April 15th, 2008, 10:00am EDT
Condition: Sarcoma
Interventions: Drug: AZD0530; Procedure: protein tyrosine kinase inhibitor therapy
Sponsors: Princess Margaret Hospital, Canada; National Cancer Institute (NCI)
Recruiting - verified April 2008 -
Combination Chemotherapy, Radiation Therapy, and Sargramostim Before and After Surgery in Treating Patients With Soft Tissue Sarcoma That Can Be Removed By Surgery
Posted: April 3rd, 2008, 10:00am EDT
Conditions: Metastatic Cancer; Sarcoma
Interventions: Drug: aerosol sargramostim; Drug: cisplatin; Drug: doxorubicin hydrochloride; Drug: ifosfamide; Drug: mitomycin C; Drug: sargramostim; Procedure: adjuvant therapy; Procedure: chemoprevention; Procedure: chemosensitization/potentiation therapy; Procedure: flow cytometry; Procedure: immunological diagnostic method; Procedure: intraoperative radiation therapy; Procedure: laboratory biomarker analysis; Procedure: multimodality therapy; Procedure: neoadjuvant therapy; Procedure: parenteral chemotherapy; Procedure: selective external radiation therapy; Procedure: therapeutic conventional surgery
Sponsors: Mayo Clinic; National Cancer Institute (NCI)
Active, not recruiting - verified April 2008 -
Combination Chemotherapy in Treating Patients Undergoing Surgery for Newly Diagnosed High-Grade Osteosarcoma
Posted: March 26th, 2008, 10:00am EDT
Condition: Sarcoma
Interventions: Drug: cisplatin; Drug: doxorubicin hydrochloride; Drug: ifosfamide; Drug: methotrexate; Procedure: adjuvant therapy; Procedure: high-dose chemotherapy; Procedure: neoadjuvant therapy; Procedure: parenteral chemotherapy; Procedure: therapeutic conventional surgery
Sponsors: Mayo Clinic; National Cancer Institute (NCI)
Active, not recruiting - verified March 2008 -
A Study of Avastin (Bevacizumab) in Combination With Standard Chemotherapy in Children and Adolescents With Sarcoma.
Posted: March 20th, 2008, 10:00am EDT
Condition: Sarcoma
Interventions: Drug: bevacizumab [Avastin]; Drug: Standard chemotherapy
Sponsor: Hoffmann-La Roche
Not yet recruiting - verified April 2008 -
A Study of R1507 in Patients With Recurrent or Refractory Sarcoma.
Posted: March 19th, 2008, 10:00am EDT
Condition: Sarcoma
Intervention: Drug: R1507
Sponsors: Hoffmann-La Roche; Sarcoma Alliance for Research through Collaboration
Recruiting - verified April 2008 -
Busulfan, Melphalan, Topotecan, and a Stem Cell Transplant in Treating Patients With Newly Diagnosed or Relapsed Solid Tumor
Posted: March 18th, 2008, 10:00am EDT
Conditions: Brain and Central Nervous System Tumors; Childhood Germ Cell Tumor; Extragonadal Germ Cell Tumor; Kidney Cancer; Neuroblastoma; Ovarian Cancer; Sarcoma; Testicular Germ Cell Tumor; Unspecified Adult Solid Tumor, Protocol Specific; Unspecified Childhood Solid Tumor, Protocol Specific
Interventions: Drug: busulfan; Drug: filgrastim; Drug: melphalan; Drug: topotecan hydrochloride; Procedure: autologous bone marrow transplantation; Procedure: autologous hematopoietic stem cell transplantation; Procedure: hematopoietic stem cell mobilization; Procedure: high-dose chemotherapy; Procedure: pharmacological study
Sponsors: Beckman Research Institute; National Cancer Institute (NCI)
Recruiting - verified March 2008 -
High Dose Methotrexate With Leucovorin Rescue With or Without Glucarpidase in Osteosarcoma
Posted: March 6th, 2008, 10:00am EST
Condition: Osteosarcoma
Interventions: Drug: glucarpidase; Drug: leucovorin
Sponsors: Protherics; M.D. Anderson Cancer Center
Not yet recruiting - verified March 2008 -
Open-Label Leucovorin Pharmacokinetic Study in Patients Receiving High Dose Methotrexate With or Without Voraxaze
Posted: March 6th, 2008, 10:00am EST
Conditions: Osteosarcoma; Leukemia; Lymphoma
Interventions: Drug: Voraxaze (glucarpidase); Drug: leucovorin
Sponsor: Protherics
Not yet recruiting - verified March 2008 -
Phase II Study of Brivanib (BMS-582664) to Treat Multiple Tumor Types
Posted: March 5th, 2008, 10:00am EST
Conditions: Advanced Non-Small Cell Lung Cancer; Transitional Cell Carcinoma; Soft Tissue Sarcoma; Gastric/Esophageal Adenocarcinoma; Pancreatic Cancer Including Ampulla of Vater
Interventions: Drug: brivanib; Drug: Placebo
Sponsor: Bristol-Myers Squibb
Not yet recruiting - verified March 2008 -
Brostallicin Clinical Trial for Myxoid Liposarcoma
Posted: March 3rd, 2008, 10:00am EST
Condition: Myxoid Liposarcoma
Intervention: Drug: Brostallicin
Sponsor: Systems Medicine LLC
Recruiting - verified March 2008 -
L-MTP-PE Compassion Access for High-Risk Osteosarcoma
Posted: February 29th, 2008, 10:00am EST
Condition: Osteosarcoma
Intervention: Drug: L-MTP-PE
Sponsor: M.D. Anderson Cancer Center
Recruiting - verified February 2008 -
Tube Feedings in Younger Patients Receiving Chemotherapy for Newly Diagnosed Acute Myeloid Leukemia, Myelodysplastic Syndrome, or High-Risk Solid Tumors
Posted: February 27th, 2008, 10:00am EST
Conditions: Brain and Central Nervous System Tumors; Kidney Cancer; Leukemia; Liver Cancer; Neuroblastoma; Sarcoma; Unspecified Childhood Solid Tumor, Protocol Specific
Interventions: Procedure: nutritional intervention; Procedure: therapeutic nutritional supplementation
Sponsors: Vanderbilt-Ingram Cancer Center; National Cancer Institute (NCI)
Completed - verified April 2008 -
BB-10901 in Treating Patients With Relapsed or Refractory Solid Tumors
Posted: February 26th, 2008, 10:00am EST
Conditions: Cervical Cancer; Gastrointestinal Carcinoid Tumor; Lung Cancer; Sarcoma; Unspecified Adult Solid Tumor, Protocol Specific
Interventions: Drug: BB-10901; Procedure: antibody-drug conjugate therapy; Procedure: monoclonal antibody therapy
Sponsor: ImmunoGen, Inc.
Suspended - verified October 2007 -
Phase I Dose-Escalation Study Of Azacitidine In Combination With Temozolomide
Posted: February 26th, 2008, 10:00am EST
Conditions: Soft Tissue Sarcoma; Mesothelioma
Intervention: Drug: Azacitidine In Combination With Temozolomide
Sponsors: Columbia University; Schering-Plough; Pharmion
Recruiting - verified February 2008 -
Bone Marrow Radiation Therapy Followed by Busulfan, Melphalan, Thiotepa, and an Autologous Stem Cell Transplant in Treating Patients With High-Risk or Relapsed Solid Tumors
Posted: February 22nd, 2008, 10:00am EST
Conditions: Brain and Central Nervous System Tumors; Kidney Cancer; Liver Cancer; Retinoblastoma; Sarcoma; Unspecified Adult Solid Tumor, Protocol Specific; Unspecified Childhood Solid Tumor, Protocol Specific
Interventions: Drug: busulfan; Drug: etoposide; Drug: filgrastim; Drug: ifosfamide; Drug: melphalan; Drug: sargramostim; Drug: thiotepa; Procedure: autologous bone marrow transplantation; Procedure: autologous hematopoietic stem cell transplantation; Procedure: colony-stimulating factor therapy; Procedure: hematologic toxicity attenuation; Procedure: high-dose chemotherapy; Procedure: intensity-modulated radiation therapy; Procedure: peripheral blood stem cell transplantation; Procedure: pharmacological study; Procedure: positron emission tomography; Procedure: systemic chemotherapy; Procedure: tomotherapy; Procedure: total marrow irradiation
Sponsors: Masonic Cancer Center at University of Minnesota; National Cancer Institute (NCI)
Recruiting - verified February 2008 -
Bortezomib and Cetuximab in Treating Patients With Advanced Solid Tumors
Posted: February 22nd, 2008, 10:00am EST
Conditions: Breast Cancer; Colorectal Cancer; Head and Neck Cancer; Kidney Cancer; Lung Cancer; Pancreatic Cancer; Sarcoma; Unspecified Adult Solid Tumor, Protocol Specific
Interventions: Drug: bortezomib; Drug: cetuximab; Procedure: enzyme inhibitor therapy; Procedure: monoclonal antibody therapy
Sponsors: Masonic Cancer Center at University of Minnesota; National Cancer Institute (NCI)
Active, not recruiting - verified March 2008 -
Bortezomib and Gemcitabine in Treating Older Patients With Advanced Solid Tumors
Posted: February 20th, 2008, 10:00am EST
Conditions: Breast Cancer; Colorectal Cancer; Head and Neck Cancer; Kidney Cancer; Lung Cancer; Ovarian Cancer; Pancreatic Cancer; Prostate Cancer; Sarcoma; Small Intestine Cancer; Unspecified Adult Solid Tumor, Protocol Specific
Interventions: Drug: bortezomib; Drug: gemcitabine hydrochloride; Procedure: antiangiogenesis therapy; Procedure: chemotherapy; Procedure: enzyme inhibitor therapy; Procedure: pharmacological study
Sponsors: Masonic Cancer Center at University of Minnesota; National Cancer Institute (NCI)
Recruiting - verified March 2008 -
Two Regimens of Combination Chemotherapy in Treating Younger Patients With Newly Diagnosed Localized Ewing Sarcoma Family of Tumors
Posted: February 19th, 2008, 10:00am EST
Condition: Sarcoma
Interventions: Drug: cyclophosphamide; Drug: doxorubicin hydrochloride; Drug: etoposide; Drug: ifosfamide; Drug: topotecan hydrochloride; Drug: vincristine; Procedure: chemotherapy; Procedure: radiation therapy; Procedure: therapeutic conventional surgery
Sponsors: Children's Oncology Group; National Cancer Institute (NCI)
Recruiting - verified May 2008
Trial - Acinic Cell Carcinoma
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CBT-1 and Paclitaxel in Treating Patients With Refractory, Recurrent, or Advanced Metastatic Solid Tumors
Posted: April 12th, 2008, 10:00am EDT
Condition: Cancer
Interventions: Drug: MDR modulator CBT-1; Drug: paclitaxel; Drug: technetium 99m sestamibi; Procedure: chemosensitization/potentiation therapy; Procedure: drug resistance inhibition treatment; Procedure: parenteral chemotherapy; Procedure: radionuclide imaging
Sponsor: National Cancer Institute (NCI)
Recruiting - verified April 2008 -
Bortezomib and Gemcitabine in Treating Older Patients With Advanced Solid Tumors
Posted: February 20th, 2008, 10:00am EST
Conditions: Breast Cancer; Colorectal Cancer; Head and Neck Cancer; Kidney Cancer; Lung Cancer; Ovarian Cancer; Pancreatic Cancer; Prostate Cancer; Sarcoma; Small Intestine Cancer; Unspecified Adult Solid Tumor, Protocol Specific
Interventions: Drug: bortezomib; Drug: gemcitabine hydrochloride; Procedure: antiangiogenesis therapy; Procedure: chemotherapy; Procedure: enzyme inhibitor therapy; Procedure: pharmacological study
Sponsors: Masonic Cancer Center at University of Minnesota; National Cancer Institute (NCI)
Recruiting