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Appendix Cancer (21 unread)

PubMed - Appendix Cancer

Appendectomy in retrograde order for complete removal of endometriosis.

Fetched: June 30th, 2009, 9:00pm EDT

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Appendectomy in retrograde order for complete removal of endometriosis.

Gynecol Endocrinol. 2009 Jun 26;:1-4

Authors: Lim MC, Song YJ, Lee DO, Jung DC, Yoo CW, Park SY

Endometriosis frequently involves the intestines. Appendectomy would be often required as part of complete removal of endometriosis. We present a patient with endometriosis who required very difficult appendectomy. For complete removal of endometriosis, hysterectomy, bilateral salpingooophorectomy, low anterior resection and accompanying pelvic peritonectomy were performed through a mid-line incision. Unexpectedly, the appendiceal tip was attached to peri-hepatic tissue with the appendix adhered to the surrounding peritoneum and bowel. Completion of the appendectomy was possible in retrograde order after extension of the surgical incision above the umbilicus. Our findings suggest that preoperative image evaluation for location or position of the appendix might be helpful in patients with suspected endometriosis to offer correct counselling, obtaining adequate consent, determining the optimal surgical approach and scheduling opportune intraoperative consultation by a colorectal surgeon.

PMID: 19562602 [PubMed - as supplied by publisher]
Squamous cell carcinoma arising in ovarian mature cystic teratoma with isolated metastasis to the appendix.

Fetched: June 30th, 2009, 9:00pm EDT

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Squamous cell carcinoma arising in ovarian mature cystic teratoma with isolated metastasis to the appendix.

J Obstet Gynaecol. 2009 Jan;29(1):71-3

Authors: Piura B, Rabinovich A, Shaco-Levy R

PMID: 19280511 [PubMed - indexed for MEDLINE]
Epithelial Appendiceal Neoplasms.

Fetched: June 27th, 2009, 9:00pm EDT

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Epithelial Appendiceal Neoplasms.

Cancer J. 2009 May/June;15(3):225-235

Authors: Sugarbaker PH

The appendiceal malignancies usually arise within a mucocele. The tumor within this structure can be minimally aggressive or of an invasive character. If a low-grade appendiceal malignancy is removed intact, recurrence does not occur. If rupture of the wall of the mucocele occurs with either low-grade or high-grade disease, the epithelial cells within will disseminate to the peritoneal surfaces. Sometimes a second-look surgery must be performed to determine if intraperitoneal spread of mucus and cancer cells has occurred. If the diagnosis of peritoneal dissemination of an appendiceal malignancy has been established, a new treatment with curative intent is indicated. Cytoreductive surgery is combined with perioperative intraperitoneal chemotherapy as a comprehensive management plan. In approximately 900 patients treated at the Washington Cancer Institute, the quantitative prognostic indicators for appendiceal cancer with peritoneal dissemination have been determined. Patients with a complete cytoreduction and low-grade tumor have an 80% survival at 20 years; with high-grade tumors, the survival drops to approximately 45%. The extent of malignancy present within the abdomen by the peritoneal cancer index has a significant impact on survival for both high-grade and low-grade disease. The most important indicator is the completeness of cytoreduction; for both high-grade and low-grade disease, all patients with an incomplete cytoreduction have died by 10 years. The presence versus absence of lymph nodal metastases on survival have minimal significance (P = 0.0495). These results of treatment can be achieved with a 19% incidence of severe complications and a 2% mortality.

PMID: 19556909 [PubMed - as supplied by publisher]
[Appendiceal mucoceles, pseudomyxoma peritonei and appendiceal mucinous neoplasms: Update on the contribution of imaging to choice of the surgical approach.]

Fetched: June 26th, 2009, 9:00pm EDT

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[Appendiceal mucoceles, pseudomyxoma peritonei and appendiceal mucinous neoplasms: Update on the contribution of imaging to choice of the surgical approach.]

J Chir (Paris). 2009 Jun 22;

Authors: Gillion JF, Franco D, Chapuis O, Serpeau D, Convard JP, Jullès MC, Balaton A, Karkouche B, Capelle P, Parmentier T, Chollet JM, Thillois JM, Berthelot G

INTRODUCTION: The treatment of pseudomyxoma peritonei (PMPs) and appendiceal mucocele (AM) has changed radically. To assess the contribution of preoperative imaging to the treatment strategy and choice of approach, a surgeon and a radiologist different from the initial radiologist examined the files of all patients treated for PMP or AM in four facilities in one district from January1, 1996, through December31, 2008. PATIENTS AND METHODS: The study included 27 patients (20 men and seven women, mean age: 63+/-13 years). Eleven patients had an intact AM, seven synchronous PMP (malignant appendiceal lesion in two of seven), six metachronous PMP (five with peritoneal mucinous carcinomatosis and one with diffuse peritoneal adenomucinosis) and three a ruptured AM but not PMP. The incidence of mucin-secreting tumors observed (27 cases in 12 years in a region of 500 000 inhabitants) corresponds to a prevalence of approximately five cases per year per million inhabitants. Acute clinical pictures (7/27) were significantly more frequent for the malignant forms (5/7) (p<0,02). RESULTS AND DISCUSSION: The overall sensitivity of computed tomography (CT) for all the criteria studied was 93%. The predictive value for AM rupture of visualization of thick calcifications was 100%. On the other hand, rupture never occurred when the CT showed an AM under pressure, with thin walls and septa. The predictive value for PMP of "scalloping" was 100%. The diagnostic accuracy of the initial reading was 25/27 for the imaging overall and 25/25 for the CT. Preoperative visualization of the exact size of the intact AM or of diagnostic information about ruptured AM and PMP helped to select an appropriate approach in 25 of 27 cases.

PMID: 19552906 [PubMed - as supplied by publisher]
[Guest comment on the article: Appendiceal mucoceles, pseudomyxoma peritonei, and appendiceal mucinous neoplasms. Update on the contribution of imaging to choice of the surgical approach, J.F. Gillion et al.]

Fetched: June 23rd, 2009, 9:00pm EDT

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[Guest comment on the article: Appendiceal mucoceles, pseudomyxoma peritonei, and appendiceal mucinous neoplasms. Update on the contribution of imaging to choice of the surgical approach, J.F. Gillion et al.]

J Chir (Paris). 2009 Jun 18;

Authors: Goere D

PMID: 19540495 [PubMed - as supplied by publisher]
Missed appendiceal adenocarcinoma diagnosed preoperatively by endoscopy with an attached transparent hood.

Fetched: June 23rd, 2009, 9:00pm EDT

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Missed appendiceal adenocarcinoma diagnosed preoperatively by endoscopy with an attached transparent hood.

Gastrointest Endosc. 2009 Mar;69(3 Suppl):761-2; discussion 762

Authors: Shinji A, Mukawa K, Nokubi M, Ohta H, Mochizuki T, Okiyama W, Yamamura N, Oguchi H, Nakamura T, Hamano H

PMID: 19251025 [PubMed - indexed for MEDLINE]
Appendiceal inversion: a diagnostic and therapeutic dilemma.

Fetched: June 18th, 2009, 9:00pm EDT

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Appendiceal inversion: a diagnostic and therapeutic dilemma.

JSLS. 2009 Jan-Mar;13(1):92-5

Authors: Johnson EK, Arcila ME, Steele SR

Appendiceal inversion is an uncommon entity that presents a diagnostic dilemma for the gastroenterologist or surgeon. We present 2 cases that illustrate scenarios that may be encountered during colonoscopy. A discussion of the literature on this subject is also presented. An improved awareness of this condition will assist the endoscopist in the identification of this finding and direct the appropriate expectant management.

PMID: 19366551 [PubMed - indexed for MEDLINE]
Appendiceal intussusception due to a fecalith mimicking a submucosal tumor.

Fetched: June 16th, 2009, 9:00pm EDT

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Appendiceal intussusception due to a fecalith mimicking a submucosal tumor.

Endoscopy. 2009;41 Suppl 2:E25-6

Authors: Lee CK, Lee SH, Park JY, Lee TH, Chung IK, Park SH, Kim HS, Kim SJ

PMID: 19219765 [PubMed - indexed for MEDLINE]
Giant appendiceal mucocele mimicking gastrointestinal stromal tumor of the cecum.

Fetched: June 16th, 2009, 9:00pm EDT

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Giant appendiceal mucocele mimicking gastrointestinal stromal tumor of the cecum.

Endoscopy. 2009;41 Suppl 2:E17-8

Authors: Akaraviputh T, Trakarnsanga A, Pongprasobchai S, Boonnuch W

PMID: 19219762 [PubMed - indexed for MEDLINE]
A single-port technique for laparoscopic extended stapled appendectomy.

Fetched: June 13th, 2009, 9:00pm EDT

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A single-port technique for laparoscopic extended stapled appendectomy.

Surg Innov. 2009 Mar;16(1):78-81

Authors: Nguyen NT, Reavis KM, Hinojosa MW, Smith BR, Stamos MJ

SUMMARY BACKGROUND DATA: Natural orifice translumenal endoscopic surgery (NOTES) has become an exciting area of surgical development. Significant limitations to this surgical concept include lack of surgical expertise and appropriate flexible instrumentation. An alternative and competing technology to NOTES is single-incision laparoscopic surgery. METHODS: This study describes a patient in whom a laparoscopic surgical technique for appendectomy used incisions that were all placed within the umbilicus. RESULTS: The operative time was 40 minutes. There were no intraoperative complications. The patient did well postoperatively and was discharged on postoperative day 1. There were no perioperative complications at 1-month follow-up. CONCLUSION: Appendectomy performed through laparoscopic incisions placed within the umbilicus was technically feasible and safe. Development of advanced flexible instrumentation and visualization platform may facilitate this new operative approach.

PMID: 19141492 [PubMed - indexed for MEDLINE]
[Appendiceal mucocele misdiagnosed with infected urachal cyst: a differential diagnosis to keep in mind]

Fetched: June 6th, 2009, 9:00pm EDT

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[Appendiceal mucocele misdiagnosed with infected urachal cyst: a differential diagnosis to keep in mind]

Actas Urol Esp. 2009 Feb;33(2):205-8

Authors: Pérez Fentes DA, Cortegoso González M, Puñal Pereira A, Cimadevila García A, Novás Castro S, Blanco Parra M

OBJECTIVE: To report one case of appendiceal mucocele misdiagnosed with an infected urachal cyst and to review their differential diagnosis, treatment and prognosis. PATIENT: We report the case of a 74-year-old-male with abdominal pain, fever and dysuria. Hypogastric abscess image in ultrasonography and CT. Percutaneous drainage and antibiotic therapy. Opaque enema, colonoscopy and cystoscopy were normal. RESULTS: Exploratory laparotomy and resection of a large cecum-fixed mass, independent to the bladder. Appendectomy and cecectomy. Pathology showed an appendiceal mucinous cystoadenoma (mucocele). CONCLUSIONS: Appendiceal mucoceles and urachal cysts are uncommon, mostly asymptomatic. Cystoadenoma or cystoadenocarcinoma mucoceles are large and can reach the midline, confounding with urachal cysts. Diagnosis by ultrasonography and/or CT. Surgical treatment in both, keeping the mucocele intact during operation to avoid the risk of pseudomyxoma peritonei.

PMID: 19418848 [PubMed - indexed for MEDLINE]
Synchronous primary tumors: appendiceal and ovarian cancer--case report.

Fetched: June 2nd, 2009, 9:00pm EDT

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Synchronous primary tumors: appendiceal and ovarian cancer--case report.

Eur J Gynaecol Oncol. 2009;30(2):237-8

Authors: Bozanović T, Ljubić A, Momcilov P, Mostić T, Vojvodić L, Vidaković S

A 64-year-old women was operated on for acute abdomen and both appendiceal and ovarian tumors were found. Histology revealed synchronous adenocarcinoma of the appendix and serous pappillary carcinoma of the right ovary. The patient was given adjuvant chemotherapy and received six cycles of cisplatinum. Regular follow-up showed no recurrence of the two synchronous primary tumors. A rare case of synchronous primary tumors of appendiceal and ovarian origin is reported. The tumors proved to be difficult to treat requiring several combined medical therapies, including surgery, chemo- and radiotherapy.

PMID: 19480268 [PubMed - in process]
Prospective Examination of Patients Suspected of Having Appendicitis Using New Computed Tomography Criteria Including "Maximum Depth of Intraluminal Appendiceal Fluid Greater Than 2.6 mm".

Fetched: May 31st, 2009, 9:00pm EDT

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Prospective Examination of Patients Suspected of Having Appendicitis Using New Computed Tomography Criteria Including "Maximum Depth of Intraluminal Appendiceal Fluid Greater Than 2.6 mm".

J Comput Assist Tomogr. 2009 May-Jun;33(3):383-9

Authors: Moteki T, Ohya N, Horikoshi H

OBJECTIVE:: The objective of this study was to perform prospective computed tomography (CT) examination of patients suspected of having appendicitis to determine whether our criteria (which include the new criterion "maximum depth of intraluminal appendiceal fluid greater than 2.6 mm") are useful for improving sensitivity and/or specificity in comparison with conventional major criteria. METHODS:: Two hundred eighty consecutive patients older than 15 years old and suspected of having appendicitis were examined using CT. We prospectively diagnosed appendicitis when a patient satisfied the following criteria (our criteria): (A) maximum appendiceal diameter greater than 6 mm in the presence or the absence of periappendiceal inflammation, (B) maximum depth of intraluminal appendiceal fluid greater than 2.6 mm, and (C) absence of an alternative lesion explaining the clinical manifestations. These patients were also prospectively examined using conventional major criteria (excluded criterion B from our criteria). Computed tomography findings were compared with the findings at surgery, pathology, and clinical follow-up. RESULTS:: Use of our criteria yielded a sensitivity of 97.3% (109/112), a specificity of 100% (168/168), and an accuracy of 98.9% (277/280) for the diagnosis of appendicitis. Using conventional major criteria, these values were 66.1% (74/112), 100% (168/168), and 86.4% (242/280), respectively, and sensitivity was lower than the value obtained using our criteria (P < 0.001 by the MacNemer test), although there is no significant difference in specificity between these criteria (P = 1 by the MacNemer test). CONCLUSIONS:: Our criteria can improve sensitivity in comparison with conventional major criteria because our criteria enabled us to differentiate appendicitis without periappendiceal inflammation from a normal appendix.

PMID: 19478631 [PubMed - in process]
Pathologic Classification and Clinical Behavior of the Spectrum of Goblet Cell Carcinoid Tumors of the Appendix.

Fetched: May 28th, 2009, 9:00pm EDT

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Pathologic Classification and Clinical Behavior of the Spectrum of Goblet Cell Carcinoid Tumors of the Appendix.

Am J Surg Pathol. 2009 May 22;

Authors: Albores-Saavedra J, Henson DE, Batich K

PMID: 19471156 [PubMed - as supplied by publisher]
Goblet Cell Carcinoid Tumors of the Appendix: Carcinoid or Adenocarcinoma.

Fetched: May 28th, 2009, 9:00pm EDT

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Goblet Cell Carcinoid Tumors of the Appendix: Carcinoid or Adenocarcinoma.

Am J Surg Pathol. 2009 May 22;

Authors: Tang LH, Klimstra DS

PMID: 19471155 [PubMed - as supplied by publisher]

Rare cancer therapy in spotlight at St. Agnes
Explore Howard County
While the procedure is often used to target appendix cancer, Esquivel said, "we think the real future for this type of procedure is colon cancer. ...

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Rare cancer therapy in spotlight at St. Agnes - Explore Baltimore County

Posted: June 17th, 2009, 10:04am EDT

Explore Baltimore County

Rare cancer therapy in spotlight at St. Agnes
Explore Baltimore County, MD
While the procedure is often used to target appendix cancer, Esquivel said, "we think the real future for this type of procedure is colon cancer." About 3000 people are diagnosed with appendix cancer nationally each year, compared with some 150000 ...

Amazing Organs: The Appendix - HealthNews

Posted: June 15th, 2009, 3:06pm EDT

HealthNews

Amazing Organs: The Appendix
HealthNews
Appendix cancer accounts for about 1 in 200 of all gastrointestinal malignancies. Appendicitis, also known as epityphlitis, is characterized by inflammation ...

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Students return with Relay for Life team in memory of area swim coach - News-Herald.com

Posted: June 12th, 2009, 11:33pm EDT

Students return with Relay for Life team in memory of area swim coach
News-Herald.com
He learned he had appendix cancer in October 2005, though he'd likely had it three years before his diagnosis, and died in May 2006 at the age of 26. ...

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Trial - Appendix Cancer

The Effectiveness of Alemtuzumab Given in Combination With CHOP and ESHAP in Patients Newly Diagnosed With Peripheral T-Cell Lymphoma (PTCL)

Posted: June 29th, 2009, 10:00am EDT

Condition: Peripheral T-Cell Lymphoma
Interventions: Drug: CHOP regimen alternate with ESHAP regimen; Drug: Alemtuzumab
Sponsors: King Chulalongkorn Memorial Hospital; Bayer
Active, not recruiting - verified June 2009
Xeloda (Capecitabine) and External Beam Radiation

Posted: June 5th, 2009, 10:00am EDT

Condition: Breast Cancer
Interventions: Radiation: Radiation Therapy; Drug: Capecitabine
Sponsor: M.D. Anderson Cancer Center
Recruiting - verified June 2009

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Appendix Cancer (21 unread)

Fetched: June 30th, 2009, 9:00pm EDT

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